Abstract: Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem cells into cardiomyocytes that overcome variability between different stem cell clones and different batch of culture medium are provided.

Abstract: Methods are provided, in some aspects, for differentiating pluripotent cells into midbrain dopaminergic (DA) neurons using a mono-SMAD inhibition or inhibition of SMAD signaling with only one SMAD inhibitor. In some embodiments, mono-SMAD inhibition utilizes a single inhibitor of bone morphogenic protein (BMP) for differentiating pluripotent cells into midbrain DA neurons.

Abstract: Methods are provided for efficient production of midbrain dopaminergic (DA) neurons. In some aspects, methods involve differentiation and selection of DA neurons for a transgenic pluripotent cell population (e.g., cells comprising a selectable marker gene). Cell populations produced by the instant methods and methods of their use are likewise provided.

Abstract: A method of manufacturing a semiconductor device includes providing a silicon substrate with multiple layers formed on a front side and a backside, wherein at least a dielectric layer is formed on the backside of the silicon substrate; defining isolation regions and active regions at the front side of the silicon substrate, wherein the active regions are separated by the isolation regions; treating the multiple layers formed at the front side and the backside of the silicon substrate, so as to remain the dielectric layer as an outermost layer exposed at the backside of the silicon substrate; and depositing a polysilicon layer on the isolation regions and the active regions at the front side of the silicon substrate.

Abstract: Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem cells into cardiomyocytes that overcome variability between different stem cell clones and different batch of culture medium are provided.

Abstract: An intelligent control faucet includes a faucet that includes a manual operation valve, an intelligent control module, a water egress tube, a cold water ingress tube, a hot water ingress tube, and a magnetic reed detection device. The water egress tube, the cold water ingress tube, and the hot water ingress tube are connected to the manual operation valve. The intelligent control module is connected, in a series manner, to the water egress tube. The magnetic reed detection device is mounted to the water egress tube and is connected through a feeding cable or directly to the intelligent control module. Water flow can be established or cut off through pulling the water egress tube so that the use is made easy.

Abstract: Methods are provided for efficient production of midbrain dopaminergic (DA) neurons. In some aspects, methods involve differentiation and selection of DA neurons for a transgenic pluripotent cell population (e.g., cells comprising a selectable marker gene). Cell populations produced by the instant methods and methods of their use are likewise provided.

Abstract: A pipeline-based processor and method. The method includes partitioning a particular pipeline into one or more base pipeline stages and a plurality of enhanced pipeline stages, each enhanced pipeline stage configured to be either a shutdown enhanced pipeline stage or an activated enhanced pipeline stage. Each enhanced pipeline stage has an enhanced stage priority level. The method also includes configuring each enhanced pipeline stage to be activated or shut down based at least on the enhanced stage priority level. The method additionally includes partitioning a particular pipeline stage into at least one base module and a plurality of enhanced modules, each enhanced pipeline stage configured to be either a shutdown enhanced pipeline stage or an activated enhanced pipeline stage. Each enhanced module has a particular priority level. The method further includes configuring each enhanced module to be activated or shut down based at least on the particular priority level.

Abstract: An intelligent control faucet includes a faucet that includes a manual operation valve, an intelligent control module, a water egress tube, a cold water ingress tube, a hot water ingress tube, and a magnetic reed detection device. The water egress tube, the cold water ingress tube, and the hot water ingress tube are connected to the manual operation valve. The intelligent control module is connected, in a series manner, to the water egress tube. The magnetic reed detection device is mounted to the water egress tube and is connected through a feeding cable or directly to the intelligent control module. Water flow can be established or cut off through pulling the water egress tube so that the use is made easy.

Abstract: An intelligent control faucet includes a faucet that includes a manual operation valve, an intelligent control module, a water egress tube, a cold water ingress tube, a hot water ingress tube, and a magnetic reed detection device. The water egress tube, the cold water ingress tube, and the hot water ingress tube are connected to the manual operation valve. The intelligent control module is connected, in a series manner, to the water egress tube. The magnetic reed detection device is mounted to the water egress tube and is connected through a feeding cable or directly to the intelligent control module. Water flow can be established or cut off through pulling the water egress tube so that the use is made easy.

Abstract: The present invention discloses a pipeline-based central processing unit, wherein the pipeline is partitioned into base pipeline stages and enhanced pipeline stages according to functions, the base pipeline stages being activated all the while, and the enhanced pipeline stages being activated or shutdown according to requirements for performance of a workload. The present invention further discloses a pipeline-based central processing unit, wherein the pipeline is partitioned into base pipeline stages and enhanced pipeline stages according to functions, each pipeline stage being partitioned into a base module and at least one enhanced module, the base module being activated all the while, and the enhanced module being activated or shutdown according to requirements for performance of a workload.

Abstract: A method for controlling a pipeline-based processor. The method includes determining a change in a workload. The method also includes activating or shutting down, by at least one controller circuit, one or more of the plurality of enhanced pipeline stages based on at least one corresponding enhanced stage priority level of the one or more of the plurality of enhanced pipeline stages and requirements for performance of the workload. The method additionally includes activating or shutting down, by the at least one controller circuit, one or more of the plurality of enhanced modules of the particular pipeline stage based on at least one corresponding priority level of the one or more of the plurality of enhanced modules of the particular pipeline stage and the requirements for the performance of the workload.

Abstract: A method of making a patterned article includes: forming a shielding layer on a substrate; patterning the shielding layer and the substrate to form a cavity that extends through the shielding layer into the substrate so as to form a recess in the substrate, the recess being defined by a recess-defining surface of the substrate; forming a color layer on the recess-defining surface of the substrate so that the color layer is defined with an indentation; and removing the shielding layer after forming the color layer.

Abstract: Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem cells into cardiomyocytes that overcome variability between different stem cell clones and different batch of culture medium are provided.

Abstract: A pipeline-based processor and method. The method includes partitioning a particular pipeline into one or more base pipeline stages and a plurality of enhanced pipeline stages, each enhanced pipeline stage configured to be either a shutdown enhanced pipeline stage or an activated enhanced pipeline stage. Each enhanced pipeline stage has an enhanced stage priority level. The method also includes configuring each enhanced pipeline stage to be activated or shut down based at least on the enhanced stage priority level. The method additionally includes partitioning a particular pipeline stage into at least one base module and a plurality of enhanced modules, each enhanced pipeline stage configured to be either a shutdown enhanced pipeline stage or an activated enhanced pipeline stage. Each enhanced module has a particular priority level. The method further includes configuring each enhanced module to be activated or shut down based at least on the particular priority level.

Abstract: The present invention discloses a method of processing instructions in a pipeline-based central processing unit, wherein the pipeline is partitioned into base pipeline stages and enhanced pipeline stages according to functions, the base pipeline stages being activated all the while, and the enhanced pipeline stages being activated or shutdown according to requirements for performance of a workload. The present invention further discloses a method of processing instructions in a pipeline-based central processing unit, wherein the pipeline is partitioned into base pipeline stages and enhanced pipeline stages according to functions, each pipeline stage being partitioned into a base module and at least one enhanced module, the base module being activated all the while, and the enhanced module being activated or shutdown according to requirements for performance of a workload.

Abstract: The present invention provides a method and an apparatus for lowering I/O power of a computer system and a computer system. According to an aspect of the present invention, there is provided a method for lowering I/O power of a computer system, comprising: buffering a plurality of ways of data to be sent to a bus; encoding each of the plurality of ways of data buffered from n bits to n+m bits based on an encoding rule, wherein n and m are both an integer larger than or equal to 1, the encoding rule is used to lower code switching frequency; and sending the plurality of ways of data encoded to the bus.

Abstract: An intelligent control faucet includes a faucet that includes a manual operation valve, an intelligent control module, a water egress tube, a cold water ingress tube, a hot water ingress tube, and a magnetic reed detection device. The water egress tube, the cold water ingress tube, and the hot water ingress tube are connected to the manual operation valve. The intelligent control module is connected, in a series manner, to the water egress tube. The magnetic reed detection device is mounted to the water egress tube and is connected through a feeding cable or directly to the intelligent control module. Water flow can be established or cut off through pulling the water egress tube so that the use is made easy.

Abstract: Methods and composition for differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including screening of optimal differentiation conditions for a selected stem cell clone in a selected batch of culture medium and use of the determined optimal condition for differentiation into a specific cell lineage.

Abstract: Methods are provided for efficient production of midbrain dopaminergic (DA) neurons. In some aspects, methods involve differentiation and selection of DA neurons for a transgenic pluripotent cell population (e.g., cells comprising a selectable marker gene). Cell populations produced by the instant methods and methods of their use are likewise provided.