Patents by Inventor Wen-Liang Chang

Wen-Liang Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10221152
    Abstract: The present invention relates to a use of mycophenolate mofetil or a pharmaceutically acceptable salt thereof in the manufacture of a medicament against influenza virus. The present invention also relates to a use of mycophenolate mofetil or a pharmaceutically acceptable salt thereof in the manufacture of a medicament against drug-resistant influenza virus strains. The present invention is further related to a method for treating influenza in a subject, comprising administering to said subject an effective amount of mycophenolate mofetil or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: March 5, 2019
    Assignee: GIANT FORCE TECHNOLOGY CORPORATION
    Inventors: An-Rong Lee, Chi-Hong Chu, Wen-Liang Chang, Chen-Wen Yao, Wen-Hsin Huang, Li-Heng Pao
  • Patent number: 10139303
    Abstract: A calibrating device, for measuring and calibrating a center of gravity of a remote control aircraft or an airfoil thereof, includes a crossbar, a first support, a second support and a control unit. The crossbar is arranged along a longitudinal axis, and includes a longitudinal rail and a slider. The slider is movably engaged with the longitudinal rail. The crossbar includes a drive member coupled with the longitudinal rail or the slider. The slider includes a pointer. The first support includes a seat and two receiving portions which are arranged on the seat and are movable along a transverse axis. The receiving portions are aligned with each other. Each receiving portion includes a load cell. The second support includes a base and a supporting portion, and the supporting portion includes a load cell. The control unit is coupled with the drive member and the three load cells.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: November 27, 2018
    Assignee: Fong Bong Enterprise Co., Ltd.
    Inventor: Wen-Liang Chang
  • Publication number: 20170322101
    Abstract: A calibrating device for measuring and calibrating a center of gravity of a remote control aircraft or an airfoil thereof is provided. The calibrating device includes a crossbar, a first support, a second support and a control unit. The crossbar is arranged along a longitudinal axis, and includes a longitudinal rail and a slider. The slider is movably engaged with the longitudinal rail. The crossbar includes a drive member coupled with the longitudinal rail or the slider. The slider includes a pointer. The first support includes a seat and two receiving portions which are arranged on the seat and are movable along a transverse axis. The receiving portions are aligned with each other. Each receiving portion includes a load cell. The second support includes a base and a supporting portion, and the supporting portion includes a load cell. The control unit is coupled with the drive member and the three load cells.
    Type: Application
    Filed: May 9, 2016
    Publication date: November 9, 2017
    Inventor: Wen-Liang Chang
  • Patent number: 9757392
    Abstract: The present invention discloses a novel use of a lanostane having the following formula (I) in enhancing uptake of nutrients: wherein R1 is either H or CH3; R2 is OCOCH3, ?O or OH; R3 is H or OH; R4 is —C(?CH2)—C(CH3)2Ra, in which Ra is H or OH, or —CH?C(CH3)—Rb, in which Rb is CH3 or CH2OH; R5 is H or OH; and R6 is CH3 or CH2OH.
    Type: Grant
    Filed: March 31, 2009
    Date of Patent: September 12, 2017
    Assignee: Sinphar Pharmaceutical Co., Ltd.
    Inventors: Hang-Ching Lin, Tsu-Chung Chang, Wen-Liang Chang, Yi-Yang Song
  • Publication number: 20160052905
    Abstract: The present invention relates to a use of mycophenolate mofetil or a pharmaceutically acceptable salt thereof in the manufacture of a medicament against influenza virus. The present invention also relates to a use of mycophenolate mofetil or a pharmaceutically acceptable salt thereof in the manufacture of a medicament against drug-resistant influenza virus strains. The present invention is further related to a method for treating influenza in a subject, comprising administering to said subject an effective amount of mycophenolate mofetil or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 22, 2013
    Publication date: February 25, 2016
    Inventors: An-Rong LEE, Chi-Hong CHU, Wen-Liang CHANG, Chen-Wen YAO, Wen-Hsin HUANG, Li-Heng PAO
  • Patent number: 9084798
    Abstract: A pharmaceutical composition for treating diabetes is provided in this invention. The composition contains a lanostane compound as a potent component. A suitable source of the lanostane compound is a Poria extract from metabolite, sclerotium, or fermentation product of Poria cocos (Schw) Wolf. The Poria extract contains 1-60% of the lanostane compounds by weight of the extract, and is devoid of secolanostane.
    Type: Grant
    Filed: August 10, 2010
    Date of Patent: July 21, 2015
    Assignee: Sinphar Tian-Li Pharmaceutical Co., Ltd (Hangzhou)
    Inventors: Hang-Ching Lin, Yu-Chuan Huang, Tsu-Chung Chang, Wen-Liang Chang
  • Patent number: 9056067
    Abstract: A pharmaceutical composition is used to enhance immunity of the human body. The composition contains potent components of lanostane compounds. A method is devised to obtain an extract from metabolite, sclerotium, or fermentation product of Poria cocas (Schw) Wolf. The extract contains 5-60% of the lanostane compounds by weight of the extract. The extract is devoid of secolanostane capable of inhibiting immunity development.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: June 16, 2015
    Assignee: Sinphar Pharmaceutical Co., Ltd.
    Inventors: Hang-Chin Lin, Jerming Tseng, Hsiou-Yu Ding, Wen-Liang Chang, Chien-Lian Chao, Hsin-Wen Huang
  • Patent number: 8993637
    Abstract: The present invention relates to a new use of citral for manufacturing a medicament for treating focal segmental glomerulosclerosis (FSGS). Particularly, the present invention discloses that citral is effective in alleviating symptoms of FSGS, including reducing glomerular epithelial hyperplasia lesions (EPHLs), peri-glomerular inflammation or glomerular hyalinosis or sclerosis, and also reducing proteinuria or hematuria or lowering serum urea nitrogen level or serum creatinine level in the subject.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: March 31, 2015
    Assignee: National Defense Medical Center
    Inventors: Ann Chen, Kuo-Feng Hua, Shuk-Man Ka, Kuo-Ping Chao, Wen-Liang Chang, Kuo-Yuan Hwa
  • Publication number: 20140343167
    Abstract: The present invention relates to a new use of citral for manufacturing a medicament for treating focal segmental glomerulosclerosis (FSGS). Particularly, the present invention discloses that citral is effective in alleviating symptoms of FSGS, including reducing glomerular epithelial hyperplasia lesions (EPHLs), peri-glomerular inflammation or glomerular hyalinosis or sclerosis, and also reducing proteinuria or hematuria or lowering serum urea nitrogen level or serum creatinine level in the subject.
    Type: Application
    Filed: April 11, 2014
    Publication date: November 20, 2014
    Applicant: National Defense Medical Center
    Inventors: Ann CHEN, Kuo-Feng HUA, Shuk-Man KA, Kuo-Ping CHAO, Wen-Liang CHANG, Kuo-Yuan HWA
  • Publication number: 20140065174
    Abstract: A pharmaceutical composition is used to enhance immunity of the human body. The composition contains potent components of lanostane compounds. A method is devised to obtain an extract from metabolite, sclerotium, or fermentation product of Poria cocos (Schw) Wolf. The extract contains 5-60% of the lanostane compounds by weight of the extract. The extract is devoid of secolanostane capable of inhibiting immunity development.
    Type: Application
    Filed: November 1, 2013
    Publication date: March 6, 2014
    Applicant: Sinphar Pharmaceutical Co., Ltd.
    Inventors: Hang-Ching Lin, Jerming Tseng, Hsiou-Yu Ding, Wen-Liang Chang, Chien-Lian Chao, Hsin-Wen Huang
  • Patent number: 8414938
    Abstract: Disclosed are an Schisandrae fructus extract for inhibition or prevention of influenza and its application, wherein the Schisandrae fructus extract is obtained by water, methanol, or ethanol extraction process and the extract comprises compounds such as schisandrone, benzoylgomisin P, wulignan A1, epigomisin O, epiwulignan A1, and tigloylgomisin P. The extracts and purified compounds of Schisandrae fructus has anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities, therefore the extracts and the purified compounds of Schisandrae fructus can be applied as an inhitibory agent of a pharmaceutical composition for treatment or prevention agent for influenza infection.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: April 9, 2013
    Assignee: National Defense Medical Center
    Inventors: Wen-Liang Chang, Chen-Wen Yao, Chi-Hong Chu, An-Rong Lee, Ann Chen, Wen-Hsin Huang, Kuo-Yuan Hwa, Chiao-Ying Chien, Chien-Yi Pai
  • Publication number: 20120196817
    Abstract: The present application relates to a method for enhancing absorption of a nutrient in a subject in need thereof with an effective amount of an isolated astragaloside compound.
    Type: Application
    Filed: April 11, 2012
    Publication date: August 2, 2012
    Applicant: NuLiv Holding Inc.
    Inventors: Hang-Ching Lin, Wen-Liang Chang, Tsu-Chung Chang, Hsiou-Yu Ding, Tian Shung Wu
  • Publication number: 20120196816
    Abstract: The present application relates to a method for enhancing absorption of a nutrient in a subject in need thereof with an effective amount of an isolated astragaloside compound.
    Type: Application
    Filed: April 11, 2012
    Publication date: August 2, 2012
    Applicant: NuLiv Holding Inc.
    Inventors: Hang-Ching Lin, Wen-Liang Chang, Tsu-Chung Chang, Hsiou-Yu Ding, Tian Shung Wu
  • Publication number: 20120189719
    Abstract: Disclosed are an Schisandrae fructus extract for inhibition or prevention of influenza and its application, wherein the Schisandrae fructus extract is obtained by water, methanol, or ethanol extraction process and the extract comprises compounds such as schisandrone, benzoylgomisin P, wulignan A1, epigomisin O, epiwulignan A1, and tigloylgomisin P. The extracts and purified compounds of Schisandrae fructus has anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities, therefore the extracts and the purified compounds of Schisandrae fructus can be applied as an inhitibory agent of a pharmaceutical composition for treatment or prevention agent for influenza infection.
    Type: Application
    Filed: November 17, 2011
    Publication date: July 26, 2012
    Applicant: NATIONAL DEFENSE MEDICAL CENTER
    Inventors: WEN-LIANG CHANG, CHEN-WEN YAO, CHI-HONG CHU, AN-RONG LEE, ANN CHEN, WEN-HSIN HUANG, KUO-YUAN HWA, CHIAO-YING CHIEN, CHIEN-YI PAI
  • Patent number: 8197860
    Abstract: The present application relates to a method for enhancing absorption of a nutrient in a subject in need thereof with an effective amount of an isolated astragaloside compound.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: June 12, 2012
    Assignee: Nuliv Holding Inc.
    Inventors: Hang-Ching Lin, Wen-Liang Chang, Tsu-Chung Chang, Hsiou-Yu Ding, Tian Shung Wu
  • Patent number: 8168596
    Abstract: A method of treating a disease associated with cartilage defect in a subject in need thereof by administering to the subject an effectively amount of a cycloartane compound of Formula (I).
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: May 1, 2012
    Assignee: NuLiv Holding Inc.
    Inventors: Wen-Liang Chang, Tsu-Chung Chang, Hang-Ching Lin, Yuan Yang, Shu-Fen Huang
  • Publication number: 20120101157
    Abstract: Disclosed are 4,5-diamino-3-halo-2-hydroxybenzoic acid derivatives and manufactures thereof. The 4,5-diamino-3-halo-2-hydroxybenzoic acid derivatives are presented by formula (I): wherein R1 group is H, CH3, or C2H5; R2 group is H, or Br; R3 group is CH3, or C3H7; and R4 group is H, or C(?NH)—NH2. 4,5-diamino-3-halo-2-hydroxybenzoic acid derivatives provided here were non-toxic to MDCK cells, particularly compounds 6a, 6b, 6c, 6e, 6f, 7a, 7b and 8 had better anti-H1N1 activity. In the future, these compounds can be used to focus on viral neuraminidases as targets to develop effective anti-influenza drugs.
    Type: Application
    Filed: October 24, 2011
    Publication date: April 26, 2012
    Applicant: NATIONAL DEFENSE MEDICAL CENTER
    Inventors: AN-RONG LEE, WEN-HSIN HUANG, CHI-HONG CHU, WEN-LIANG CHANG, CHEN-WEN YAO, I-LING CHEN
  • Patent number: 7959952
    Abstract: A method for skin care includes administering the water insoluble fraction of Astragalus membranaceus, or astragaloside compounds thereof to a subject in need thereof at an effective amount for improving skin texture, reducing wrinkles, UV protection, and/or providing an anti-aging effect.
    Type: Grant
    Filed: September 1, 2006
    Date of Patent: June 14, 2011
    Assignee: Nuliv Holding Inc.
    Inventors: Wen-Liang Chang, Tsu-Chung Chang, Hang-Ching Lin, Yuan Yang
  • Publication number: 20110053899
    Abstract: A pharmaceutical composition for treating diabetes is provided in this invention. The composition contains a lanostane compound as a potent component. A suitable source of the lanostane compound is a Poria extract from metabolite, sclerotium, or fermentation product of Poria cocos (Schw) Wolf. The Poria extract contains 1-60% of the lanostane compounds by weight of the extract, and is devoid of secolanostane.
    Type: Application
    Filed: August 10, 2010
    Publication date: March 3, 2011
    Applicant: SINPHAR TIAN-LI PHARMACEUTICAL CO., LTD (HANGZHOU)
    Inventors: Hang-Ching Lin, Yu-Chuan Huang, Tsu-Chung Chang, Wen-Liang Chang
  • Publication number: 20100298283
    Abstract: A pharmaceutical composition is used to enhance immunity of the human body. The composition contains potent components of lanostane compounds. A method is devised to obtain an extract from metabolite, sclerotium, or fermentation product of Poria cocos (Schw) Wolf. The extract contains 5-60% of the lanostane compounds by weight of the extract. The extract is devoid of secolanostane capable of inhibiting immunity development.
    Type: Application
    Filed: July 19, 2010
    Publication date: November 25, 2010
    Applicant: Sinphar Pharmaceutical Co., Ltd.
    Inventors: Hang-Ching Lin, Jerming Tseng, Hsiou-Yu Ding, Wen-Liang Chang, Chien-Lian Chao, Hsin-Wen Huang