Abstract: Disclosed are a class of compounds having a new structure as an ATR inhibitor, and a stereoisomer, an optical isomer, a pharmaceutical salt, a prodrug and a solvate thereof. An in-vitro enzyme inhibitory activity study shows that the compounds have a strong inhibitory effect on an ATR enzyme, and can be used as prospecting compounds for treating ATR-mediated diseases.

Abstract: Disclosed are combination therapies comprising administration of a CD73 inhibitor and an adenosine A2A or A2B receptor inhibitor. The disclosed combination therapies are useful in the treatment of diseases related to the activity of adenosine receptors and/or CD73 including, for example, cancer, inflammatory diseases, cardiovascular diseases, and neurodegenerative diseases. Anti-CD73 antibodies and A2A/A2B inhibitors are also disclosed.

Abstract: In some examples, a touch and force sensitive device includes integrated circuitry configured to attenuate noise in a first period of operation, and sense force of an object contacting the device in a second period of operation. In some examples, a touch and force sensitive device includes integrated circuitry formed from a same material layer, the material layer configured to detect a force of an object contacting the device in first one or more regions of the material layer, and configured to couple touch detection circuitry in second one or more regions of the material layer.

Abstract: A lens, a vehicle lamp, and a corresponding vehicle, the lens including a lens portion with a touch area and an antenna portion including a flange portion, the antenna portion being electrically conductive and at least partially opposite to the touch area. When the touch area of the lens provided with the antenna portion is touched, the capacitance of a capacitor formed by the antenna portion will change.

Abstract: A circuit for controlling failure of a vehicle MCU includes: a failure state detector, configured to monitor the state of a MCU circuit in real time; a maintaining voltage signal generator, configured to: when the MCU circuit is detected to be in a failure state, convert a voltage from an ignition coil of a vehicle to form a failure maintaining voltage signal; and a driving maintainer, configured to output the failure maintaining voltage signal to a driving controller of each load in the vehicle so as to maintain the normal work of the driving controller.

Abstract: A screw compressor slide valve with gas pulsation attenuation function includes valve walls and internal through holes. A screw compressor includes the screw compressor slide valve. A part of exhausted gas of the screw compressor is directly discharged from an exhaust port to an exhaust chamber to form a main exhaust flow channel; another part of the exhausted gas is discharged from the exhaust port into the exhaust chamber after being delayed by the internal through holes, which forms a branched exhaust flow channel. Since the branched exhaust flow channel is longer than the main exhaust flow channel, when the gas pulsation in the branched exhaust flow channel lags behind that in the main exhaust flow channel by 180-degree in phase, two gas pulsations in the two flow channels are offset due to opposite gas pulsation phases, which attenuates the gas pulsation, thereby suppressing induced vibration and noise.

Abstract: A communications server apparatus for managing a request for transport-related services, which is configured to, in response to receiving user request data, generate a data record having a plurality of transit point data fields having data for a corresponding plurality of transit points from an origin to a destination, including a variable transit point data field having data that is determined based on data associated with at least one transportation network-related parameter, and having a plurality of trip section data fields for a corresponding plurality of trip sections defining navigation directions from the origin to the destination, and, for each trip section data field, to associate the trip section data field with a respective transit point data field, and, based on the data of the associated transit point data field, to determine a respective transportation mode and to generate transit data in respect of the respective transportation mode.

Abstract: A lens, a vehicle lamp, and a corresponding vehicle, the lens including a lens portion with a touch area and an antenna portion including a flange portion, the antenna portion being electrically conductive and at least partially opposite to the touch area. When the touch area of the lens provided with the antenna portion is touched, the capacitance of a capacitor formed by the antenna portion will change.

Abstract: The present invention relates to a method for securely connecting a vehicle and a Bluetooth key, a vehicle Bluetooth module and a Bluetooth key.

Abstract: The present application provides a pipeline adapter including a first connection block, a second connection block, a fastener and a seal ring. The first connection block is provided with a first channel and a first annular positioning groove disposed around the first channel. The second connection block is provided with a second channel communicating with the first channel and a second annular positioning platform fitting inside the first annular positioning groove. The second annular positioning platform is disposed around the second channel. The fastener connects the first connection block to the second connection block. The seal ring fits between the first annular positioning groove and the second annular positioning platform. The pipeline adapter is convenient to use, has a favorable sealing effect, and facilitates pipeline connection of a refrigeration system.

Abstract: A method of solving closed form exact solution for the field generated by a finite-length harmonic linear current source in a whole space. The vector magnetic potential formula of the finite-length harmonic linear current source containing a source point position vector is listed, the uniform current is subjected to cosine processing, and the current in the vector magnetic potential formula of the harmonic linear current source is expressed by a cosine function. The vector magnetic potential formula can be subjected to quadrature by an elementary function to obtain the closed form exact solution for the field generated by the finite-length harmonic linear current source in whole space. The cosine expression of the linear current source can better reflect the fundamental attributes of the electric dipole and harmonic current of linear current source in the conductive whole space. The obtained closed form exact solution is applicable in the all zone.

Abstract: Communications server apparatus (102) for managing payloads (202, 204) for transport by a vehicle (408), and methods for the operation thereof. The communications server apparatus is configured to, for a plurality of payloads of respective different payload categories (202, 204), each payload category being associated with unique vehicle capability requirements, determine (206), for a first payload of a first payload category, a value of a first payload attribute parameter indicative of a first vehicle capability requirement. For a second payload of a second payload category, a value of a second payload attribute parameter indicative of a second vehicle capability requirement is determined (208). The values for the first and second payload attribute parameters are compared (210) with payload capability data associated with the vehicle, and a comparison result is used (212) to determine a capability of the vehicle to transport both the first and second payloads.

Abstract: A screw compressor slide valve with gas pulsation attenuation function includes valve walls and internal through holes. A screw compressor includes the screw compressor slide valve. A part of exhausted gas of the screw compressor is directly discharged from an exhaust port to an exhaust chamber to form a main exhaust flow channel; another part of the exhausted gas is discharged from the exhaust port into the exhaust chamber after being delayed by the internal through holes, which forms a branched exhaust flow channel. Since the branched exhaust flow channel is longer than the main exhaust flow channel, when the gas pulsation in the branched exhaust flow channel lags behind that in the main exhaust flow channel by 180-degree in phase, two gas pulsations in the two flow channels are offset due to opposite gas pulsation phases, which attenuates the gas pulsation, thereby suppressing induced vibration and noise.

Abstract: A communications server apparatus for managing a request for transport-related services, which is configured to, in response to receiving user request data, generate a data record having a plurality of transit point data fields having data for a corresponding plurality of transit points from an origin to a destination, including a variable transit point data field having data that is determined based on data associated with at least one transportation network-related parameter, and having a plurality of trip section data fields for a corresponding plurality of trip sections defining navigation directions from the origin to the destination, and, for each trip section data field, to associate the trip section data field with a respective transit point data field, and, based on the data of the associated transit point data field, to determine a respective transportation mode and to generate transit data in respect of the respective transportation mode.

Abstract: A method of solving closed form exact solution for the field generated by a finite-length harmonic linear current source in a whole space. The vector magnetic potential formula of the finite-length harmonic linear current source containing a source point position vector is listed, the uniform current is subjected to cosine processing, and the current in the vector magnetic potential formula of the harmonic linear current source is expressed by a cosine function. The vector magnetic potential formula can be subjected to quadrature by an elementary function to obtain the closed form exact solution for the field generated by the finite-length harmonic linear current source in whole space. The cosine expression of the linear current source can better reflect the fundamental attributes of the electric dipole and harmonic current of linear current source in the conductive whole space. The obtained closed form exact solution is applicable in the all zone.

Abstract: The present application provides a pipeline adapter including a first connection block, a second connection block, a fastener and a seal ring. The first connection block is provided with a first channel and a first annular positioning groove disposed around the first channel. The second connection block is provided with a second channel communicating with the first channel and a second annular positioning platform fitting inside the first annular positioning groove. The second annular positioning platform is disposed around the second channel. The fastener connects the first connection block to the second connection block. The seal ring fits between the first annular positioning groove and the second annular positioning platform. The pipeline adapter is convenient to use, has a favorable sealing effect, and facilitates pipeline connection of a refrigeration system.

Abstract: Disclosed is an oil separation barrel, which includes a barrel body and an oil separation and filtration structure provided in the barrel body, the barrel body provided with an oil separation cavity and an output port. An output gas flow is filtered by the oil separation and filtration structure, then enters the oil separation cavity, and finally is output from the output port. At least part of a barrel wall of the barrel body forming the oil separation cavity includes two or more layers of circumferential walls. The output gas flow flows in the oil separation cavity in such a manner that it changes the advance direction multiple times, which can make the flow field uniform and reduce noise and vibration; and the output gas flow impacts the circumferential wall surfaces in the oil separation barrel multiple times, which can further improve the efficiency of oil separation.

Abstract: A screw compressor and a compressor body thereof, in which the compressor body includes a housing provided with a suction inlet and a discharge end face, the housing is internally provided with a rotor chamber and a spool chamber, the housing is provided with a cooling chamber around the rotor chamber, the cooling chamber communicates with the suction inlet, and the cooling chamber is provided with an air inlet communicating with the rotor chamber.

Abstract: Disclosed is an oil separation barrel, which includes a barrel body and an oil separation and filtration structure provided in the barrel body, the barrel body provided with an oil separation cavity and an output port. An output gas flow is filtered by the oil separation and filtration structure, then enters the oil separation cavity, and finally is output from the output port. At least part of a barrel wall of the barrel body forming the oil separation cavity includes two or more layers of circumferential walls. The output gas flow flows in the oil separation cavity in such a manner that it changes the advance direction multiple times, which can make the flow field uniform and reduce noise and vibration; and the output gas flow impacts the circumferential wall surfaces in the oil separation barrel multiple times, which can further improve the efficiency of oil separation.