Patents by Inventor Wen-Shen Chu

Wen-Shen Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioconversion of cephalosporin C to glutaryl-7-aminocephalosporanic acid
    Patent number: 5597704
    Abstract: A method of converting cephalosporin C to glutaryl-7-aminocephalosporanic acid. The method including obtaining a cell preparation from a microorganism which produces D-amino acid oxidase, the preparation being a cell-free extract or a suspension of permeated cells; adding a D-.alpha.-amino acid to the preparation; after the adding step, heating the preparation at 50.degree.-75.degree. C. for 5-60 minutes; and incubating cephalosporin C in the preparation. Also disclosed are a method of converting cephalosporin C to glutaryl-7-aminocephalosporanic acid in the absence of exogenous H.sub.2 O.sub.2, and a method of screening for a D-amino acid oxidase-producing microorganism.
    Type: Grant
    Filed: May 1, 1995
    Date of Patent: January 28, 1997
    Assignee: Food Industry Research and Development Institute
    Inventors: Yun-Huey Lee, Wen-Shen Chu, Wen-Hwei Hsu