Patents by Inventor Wenchao Wang
Wenchao Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200010471Abstract: The present invention provides a novel inhibitor of FLT3 kinase, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, ester, acid, metabolite or prodrug thereof. The present invention also provides a pharmaceutical composition comprising the compound of formula (I), as well as the use and method for preventing or treating FLT3-related conditions, especially conditions related to mutant FLT3 kinase (particularly, FLT3/ITD mutant kinase).Type: ApplicationFiled: June 5, 2017Publication date: January 9, 2020Applicant: PRECEDO PHARMACEUTICALS CO., LTDInventors: Qingsong LIU, Jing LIU, Xixiang LI, Aoli WANG, Ziping QI, Hong WU, Jiaxin WU, Wenchao WANG, Chen HU, Cheng CHEN, Li WANG, Beilei WANG
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Publication number: 20190330707Abstract: Provided is a method for the high expression of a recombinant human serum albumin, characterized in comprising the step of co-expressing: (a) a human serum albumin gene, and (b) one or more rHSA expression promoting factor genes in a yeast host cell.Type: ApplicationFiled: May 4, 2017Publication date: October 31, 2019Applicant: Shenzhen Protgen Ltd.Inventors: Guodong Chang, Xin Dou, Xiaobo Xiong, Wenchao Wang
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Publication number: 20190238327Abstract: The present disclosure provides a cross-blockchain data access method, apparatus and system, and a computer readable medium. The method comprises: sending an authorizing blockchain apparatus a block data request carrying a requesting blockchain apparatus identifier and authorization information, so that the authorizing blockchain apparatus verifies whether the authorization information corresponding to locally-stored requesting blockchain apparatus identifier is matched with the authorization information in the block data request; receiving block data sent by the authorizing blockchain apparatus and corresponding to the block data request, the block data being sent after the authorizing blockchain apparatus verifies that the authorization information corresponding to locally-stored requesting blockchain apparatus identifier is matched with the authorization information in the block data request.Type: ApplicationFiled: November 15, 2018Publication date: August 1, 2019Applicant: BAIDU ONLINE NETWORK TECHNOLOGY (BEIJING) CO., LTD.Inventors: Feng LI, Wei Xiao, Yunpeng Wang, Zhiyuan Yu, Wenchao Wang, Shihui Zhou, Xianghui Zhao
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Patent number: 10350210Abstract: The present application provides a compound of formula I, which is a EGFR and ALK dual inhibitor and can be used alone or in combination with other therapeutic agents to treat diseases such as non-small cell lung cancer. The compounds of the present application are useful in the treatment of diseases carrying the EGFR wild-type gene, or carrying the EGFR T790M mutant gene and/or the EGFR L858R mutant gene and/or the EGFR delE746_A750 mutant gene, or in the treatment of diseases carrying the ALK wild-type gene, ALK F1174L mutant gene and/or ALK F1196M gene and/or EML4-ALK mutant gene and/or NPM-ALK mutant gene, and can be used in the first-line treatment of anaplastic lymphoma kinase (ALK) positive late-stage non-small cell Lung cancer.Type: GrantFiled: December 15, 2016Date of Patent: July 16, 2019Assignee: PRECEDO PHARMACEUTICALS CO., LTDInventors: Jing Liu, Qingsong Liu, Taoshan Jiang, Aoli Wang, Jiaxin Wu, Hong Wu, Ziping Qi, Yongfei Chen, Fengming Zou, Wenchao Wang, Zheng Zhao, Li Wang, Beilei Wang
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Publication number: 20190182223Abstract: Establishing a connection is disclosed including acquiring an authentication code, sending data including the authentication code to a management server, receiving parameter information sent back by the management server after the management server performed a successful authentication using the data including the authentication code, and establishing, using the parameter information, a channel to a connection server.Type: ApplicationFiled: December 11, 2018Publication date: June 13, 2019Inventors: Wenchao Wang, Chunhui Zhang, Yanming Cai, Ji Zhao
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Publication number: 20190182070Abstract: Event processing associated with a smart device is disclosed, including: receiving an indication of an event detected by a function module associated with a smart device; determining, based at least in part on event registration information, that an event message is to be sent to a cloud device; and sending the event message to the cloud device. Event processing associated with a smart device also includes: receiving an indication of an event detected by a first function module associated with a smart device; determining, based at least in part on event registration information, that a control message is to be sent to a second function module associated with the smart device; and sending the control message to the second function module associated with the smart device.Type: ApplicationFiled: December 10, 2018Publication date: June 13, 2019Inventors: Jiangbo Yang, Chunhui Zhang, Yanming Cai, Ji Zhao, Wenchao Wang, Nan Zhang, Hujia Liu
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Publication number: 20190182332Abstract: Action processing associated with a cloud device is disclosed, including: in response to a trigger comprising receiving a forwarding instruction from a control device or receiving an event message from a first smart device, sending an action message to a second smart device, wherein the action message comprises at least an action identifier, wherein the action identifier corresponds to a control instruction to be executed at the second smart device; and receiving an action response message from the second smart device, wherein the action response message comprises the action identifier and an action status identifier, wherein the action status identifier is associated with an execution status of the control instruction at the second smart device.Type: ApplicationFiled: December 10, 2018Publication date: June 13, 2019Inventors: Jiangbo Yang, Chunhui Zhang, Yanming Cai, Ji Zhao, Wenchao Wang, Nan Zhang, Hujia Liu
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Patent number: 10266535Abstract: Provided in the present invention is a novel inhibitor of FLT3 kinase, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, ester, acid, metabolite or prodrug thereof. Also provided in the present invention are a pharmaceutical composition comprising a compound of formula (I) and a use and method for preventing or treating cell proliferative conditions and/or FLT3-related conditions, in particular for conditions responding to the inhibition of FLT3 kinase (especially FLT3/ITD mutant kinases).Type: GrantFiled: August 7, 2015Date of Patent: April 23, 2019Assignees: HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCES, HEFEI COSOURCE PHARMACEUTICAL CO., LTD.Inventors: Jing Liu, Qingsong Liu, Xixiang Li, Aoli Wang, Hong Wu, Cheng Chen, Wenchao Wang, Chen Hu, Zheng Zhao, Jiaxin Wu, Juan Liu, Kailin Yu, Wei Wang, Li Wang, Beilei Wang
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Publication number: 20190084960Abstract: The present invention provides a compound represented by formula (I), or a pharmaceutically acceptable salt, a solvate, an ester, an acid, a metabolite or a prodrug thereof. The compound itself in the present invention or in combination with at least one therapeutic agent can be used for preventing or treating diseases, disorders or symptoms caused by the adjustment of the activity of tyrosine kinase C-KIT, or affected by the activity of the tyrosine kinase C-KIT or involving in the activity of the tyrosine kinase C-KIT, especially cancers or other cell proliferation diseases.Type: ApplicationFiled: March 28, 2017Publication date: March 21, 2019Applicants: PRECEDO PHARMACEUTICALS CO., LTD, HEFEI GRACEVO BIO-MEDICINE CO., LTDInventors: Qingsong LIU, Jing LIU, Qiang WANG, Beilei WANG, Feiyang LIU, Shuang QI, Ziping QI, Fengming ZOU, Cheng CHEN, Wenchao WANG, Chen HU, Xiaochuan LIU, Wei WANG, Aoli WANG, Li WANG, Zhenquan HU, Tao REN
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Publication number: 20190040013Abstract: The present invention provides an inhibitor of Bruton's tyrosine kinase, which is a compound of formula (I), or its pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug. The present invention also provides a pharmaceutical composition comprising the compound. The present invention also provides a method for inhibiting the activity of tyrosine kinase activity or for treating a disease, disorder, or condition, which would benefit from the inhibition of Bruton's tyrosine kinase(s), by using the Bruton's tyrosine kinase inhibitor, as well application of the Bruton's tyrosine kinase inhibitor for the same.Type: ApplicationFiled: December 22, 2016Publication date: February 7, 2019Applicant: HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCESInventors: Jing LIU, Qingsong LIU, Qianmao LIANG, Yongfei CHEN, Cheng CHEN, Aoli WANG, Hong WU, Kailin YU, Wei WANG, Chen HU, Wenchao WANG, Shuang QI, Beilei WANG, Li WANG
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Publication number: 20190010159Abstract: The present application provides a compound of Formula (I) as an inhibitor against wild-type EGFR and/or mutant EGFR, which may be used for treating human non-small cell lung cancer individually or in combination with other therapeutic agent(s). The compound of Formula (I) of the present application may be used for treating patients of drug-resistant human non-small cell lung cancer harboring wild-type EGFR and/or EGFR T790M mutation and/or EGFR L858R mutation and/or EGFR delE746_A750 mutation.Type: ApplicationFiled: December 27, 2016Publication date: January 10, 2019Applicant: PRECEDO PHARMACEUTICALS CO., LTDInventors: Qingsong LIU, Jing LIU, Xixiang LI, Aoli WANG, Hong WU, Kailin YU, Chen HU, Wenchao WANG, Cheng CHEN, Fengming ZOU, Ziping QI, Li WANG, Beilei WANG
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Publication number: 20180369242Abstract: The present application provides a compound of formula I, which is a EGFR and ALK dual inhibitor and can be used alone or in combination with other therapeutic agents to treat diseases such as non-small cell lung cancer. The compounds of the present application are useful in the treatment of diseases carrying the EGFR wild-type gene, or carrying the EGFR T790M mutant gene and/or the EGFR L858R mutant gene and/or the EGFR delE746_A750 mutant gene, or in the treatment of diseases carrying the ALK wild-type gene, ALK F1174L mutant gene and/or ALK F1196M gene and/or EML4-ALK mutant gene and/or NPM-ALK mutant gene, and can be used in the first-line treatment of anaplastic lymphoma kinase (ALK) positive late-stage non-small cell Lung cancer.Type: ApplicationFiled: December 15, 2016Publication date: December 27, 2018Applicant: PRECEDO PHARMACEUTICALS CO., LTDInventors: Jing LIU, Qingsong LIU, Taoshan JIANG, Aoli WANG, Jiaxin WU, Hong WU, Ziping QI, Yongfei CHEN, Fengming ZOU, Wenchao WANG, Zheng ZHAO, Li WANG, Beilei WANG
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Patent number: 10135021Abstract: An frit-sealed device comprising a resistive heating element having an electrically-closed-loop structure and process for frit-sealing a device by using such heating element. The element can be advantageously made of a metal such as Invar® and/or Kovar®. The invention enables hermetic frit sealing with low residual stress in the seal. The invention is particularly advantageous for hermetic sealing of OLED display devices.Type: GrantFiled: February 29, 2008Date of Patent: November 20, 2018Assignee: Corning IncorporatedInventor: Wenchao Wang
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Patent number: 9902641Abstract: A mold for shaping glass-based material can include a mold body having a surface, wherein at least a portion of the mold body near the surface comprises at least about 90% by weight nickel and from about 0.2% to about 0.35% by weight manganese; and a nickel oxide layer on the surface of the mold body. The nickel oxide layer has first and second opposing surfaces wherein the first surface of the nickel oxide layer contacts and faces the surface of the mold body and the second surface of the nickel oxide layer includes a plurality of grains. The plurality of grains has an average grain size of about 150 ?m or less.Type: GrantFiled: March 16, 2016Date of Patent: February 27, 2018Assignee: CORNING INCORPORATEDInventors: Jill Marie Hall, Nicholas Scott Ryan, Wenchao Wang, Kim E Womer
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Publication number: 20180030054Abstract: Provided in the present invention is a novel inhibitor of FLT3 kinase, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, ester, acid, metabolite or prodrug thereof. Also provided in the present invention are a pharmaceutical composition comprising a compound of formula (I) and a use and method for preventing or treating cell proliferative conditions and/or FLT3-related conditions, in particular for conditions responding to the inhibition of FLT3 kinase (especially FLT3/ITD mutant kinases).Type: ApplicationFiled: August 7, 2015Publication date: February 1, 2018Applicants: HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCES, HEFEI COSOURCE PHARMACEUTICAL CO., LTD.Inventors: Jing LIU, Qingsong LIU, Xixiang LI, Aoli WANG, Hong WU, Cheng CHEN, Wenchao WANG, Chen HU, Zheng ZHAO, Jiaxin WU, Juan LIU, Kailin YU, Wei WANG, Li WANG, Beilei WANG
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Patent number: 9814709Abstract: The present invention provides a Bruton's tyrosine kinase inhibitor, which is a compound represented by formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. The present invention also provides a pharmaceutical composition comprising the compound. The present invention also provides a method and use of using the Bruton's tyrosine kinase inhibitor to inhibit the tyrosine kinase activity or treat diseases, disorders or symptoms benefiting from the inhibition of the Bruton's tyrosine kinase (Btk) activity.Type: GrantFiled: January 27, 2015Date of Patent: November 14, 2017Assignees: HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCES, ANHUI NEW STAR PHARMACEUTICAL DEVELOPMENT CO., LTD.Inventors: Qingsong Liu, Jing Liu, Yongfei Chen, Hong Wu, Aoli Wang, Beilei Wang, Chen Hu, Wenchao Wang, Cheng Chen
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Patent number: 9813297Abstract: A method for identifying an application scenario of a terminal device, where the method includes analyzing an application program running on a terminal device by means of compilation to obtain characteristic data of the application program; and determining, from a scenario characteristic data set according to the characteristic data of the application program, application scenario information corresponding to the characteristic data of the application program, where the scenario characteristic data set includes a correspondence between multiple types of application scenario information and characteristic data of multiple application programs. Because characteristic data of an application program is more likely to be unique in describing a corresponding application scenario, application scenario information corresponding to the characteristic data of the application program is relatively accurate.Type: GrantFiled: July 30, 2015Date of Patent: November 7, 2017Assignee: HUAWEI TECHNOLOGIES CO., LTD.Inventors: Wenchao Wang, Yaocang Jia, Jing Zhu
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Publication number: 20170128439Abstract: The present invention provides a Bruton's tyrosine kinase inhibitor, which is a compound represented by formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. The present invention also provides a pharmaceutical composition comprising the compound. The present invention also provides a method and use of using the Bruton's tyrosine kinase inhibitor to inhibit the tyrosine kinase activity or treat diseases, disorders or symptoms benefiting from the inhibition of the Bruton's tyrosine kinase (Btk) activity.Type: ApplicationFiled: January 27, 2015Publication date: May 11, 2017Inventors: Qingsong LIU, Jing LIU, Yongfei CHEN, Hong WU, Aoli WANG, Beilei WANG, Chen HU, Wenchao WANG, Cheng CHEN
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Patent number: 9475723Abstract: A mold for shaping glass can be made by a method that includes providing a mold body having a shaping surface comprising at least about 90% nickel and modifying the composition of the shaping surface of the mold body by exposing the shaping surface to an oxidizing heat treatment. The oxidizing heat treatment may include a ramping heat treatment, a fixed heat treatment, or both the ramping heat treatment and the fixed heat treatment. The ramping heat treatment may include increasing a heating temperature at a rate from about 20° C./hour to about 500° C./hour to a temperature from about 700° C. to about 1000° C. The fixed heat treatment may include holding the heating temperature from about 700° C. to about 1000° C. for a holding time of at least about 5 minutes.Type: GrantFiled: August 26, 2015Date of Patent: October 25, 2016Assignee: Corning IncorporatedInventors: Kristen Marie Horn, David Myron Lineman, Kevin Thomas Morris, Wenchao Wang, Kim E. Womer
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Publication number: 20160272530Abstract: A mold for shaping glass-based material can include a mold body having a surface, wherein at least a portion of the mold body near the surface comprises at least about 90% by weight nickel and from about 0.2% to about 0.35% by weight manganese; and a nickel oxide layer on the surface of the mold body. The nickel oxide layer has first and second opposing surfaces wherein the first surface of the nickel oxide layer contacts and faces the surface of the mold body and the second surface of the nickel oxide layer includes a plurality of grains. The plurality of grains has an average grain size of about 150 ?m or less.Type: ApplicationFiled: March 16, 2016Publication date: September 22, 2016Inventors: Jill Marie Hall, Nicholas Scott Ryan, Wenchao Wang, Kim E. Womer