Abstract: Medical material production and preparation, and a preparation method of a 4D chitosan-based thermosensitive hydrogel. First, chitosan is dissolved in acetic acid solution; a chitosan-based thermosensitive hydrogel is printed by a 4D bioprinter and lyophilized after solvent extraction, to obtain lyophilized chitosan; subsequently, aqueous ?-sodium glycerophosphate solution is prepared with ultrapure water and ?-sodium glycerophosphate, and then aqueous carboxymethyl chitosan solution is prepared with ultrapure water and aqueous ?-sodium glycerophosphate solution are charged into and mixed well with aqueous carboxymethyl chitosan solution to prepare a mixture; finally, the lyophilized chitosan is crosslinked with the mixture to obtain the 4D chitosan-based thermosensitive hydrogel. With scientific and reliable principles thereof, the present invention solves a problem that conventional thermosensitive hydrogels have uneven pore sizes, and improves the entrapment efficiency and ability of limbal stem cells.

Abstract: Dual-cure compositions for use in high temperature adhesive applications, and particularly for temporarily adhesively attaching one substrate to another substrate, are provided. These dual-cure adhesives are silicone-based compositions that can be B-staged by exposure UV radiation to provide initial green strength, followed by a C-stage cure to give adhesives that can survive high temperature processes above 200° C., especially above 300° C., yet easy to debond afterwards to allow separation of the top and bottom substrates.

Abstract: Provided are a display substrate, a display module and a display device. The display substrate has a display region and a test pad region, and includes: a base; at least one pad on the base and in the test pad region; a first spacing layer on a side of the pad away from the base; multiple support parts and at least one test signal line in the test pad region and on a side of the first spacing layer away from the base, each test signal line has one end connected to one pad and another end connected to an array test device; at least two of the support parts are arranged along a first direction intersecting a direction pointing to the test pad region from the display region, each support part has a support end projecting from a surface of the test signal line away from the base.

Abstract: Described here is are antibodies to CCR8 having enhanced binding, ligand blocking and antibody dependent cellular cytotoxicity. Also described is are methods of treating a cancer by targeting tumor infiltrating lymphocytes in a cancer patient using a formulation comprising a CCR8 antibody described above.

Abstract: A chrome-free tanning process of an ecological leather is characterized by a TWS+sodium lignosulfonate+TWLZ ternary tanning process system. The sodium lignosulfonate added can not only have a fixation effect on a TWS tanning agent to make the TWS tanning not undergo detanning at a low pH, but also significantly improve the uniformity of distribution of a TWLZ tanning agent in a hide/skin and promote the formation of a stable cross-linked network structure by the TWLZ tanning agent in a collagen fiber, which effectively overcomes the defects of tanning performance of the existing tanning systems to obtain a leather with uniform and sufficient tanning, a high isoelectric point, a strong electropositivity, excellent absorption for post-tanning chemicals, and a prominent softness, and gives a leather a wide use range and a high quality.

Abstract: A chrome-free tanning process of an ecological leather is characterized by a TWS+sodium lignosulfonate+TWLZ ternary tanning process system. The sodium lignosulfonate added can not only have a fixation effect on a TWS tanning agent to make the TWS tanning not undergo detanning at a low pH, but also significantly improve the uniformity of distribution of a TWLZ tanning agent in a hide/skin and promote the formation of a stable cross-linked network structure by the TWLZ tanning agent in a collagen fiber, which effectively overcomes the defects of tanning performance of the existing tanning systems to obtain a leather with uniform and sufficient tanning, a high isoelectric point, a strong electropositivity, excellent absorption for post-tanning chemicals, and a prominent softness, and gives a leather a wide use range and a high quality.

Abstract: The present disclosure provides use of Clostridium ghonii combined with a tumor angiogenesis inhibitor in preparing a pharmaceutical product for treating a tumor. The present disclosure further provides a drug for treating a tumor, where the drug includes active ingredients of Clostridium ghonii and a tumor angiogenesis inhibitor.

Abstract: The present disclosure relates to use of a Clostridium ghonii spore combined with pembrolizumab in cancer treatment. It is found for the first time that the Clostridium ghonii spore combined with pembrolizumab can significantly improve a curative effect of colon cancer and reduce a dose of the pembrolizumab, and thus is efficient and low-toxic. Oncolysis by Clostridium ghonii can affect immunogenicity of a tumor microenvironment (TME) by various ways, converts an immunosuppressive state of the TME into an immune-activated state, adjusts the immunosuppressive TME, and breaks an immune tolerance. An optimal combination of the Clostridium ghonii spore and the pembrolizumab thoroughly removes about 20% of mouse tumor tissues. A benefit range of patients with tumors treated by a PD-1 antibody is expanded. The combination even has an obvious curative effect on patients failed the treatment by the PD-1 antibody.

Abstract: Curable heat-expanding debondable coating compositions for use as a pre-coating or surface preparation in conjunction with adhesive composition. The debondable coating compositions include heat-expandable microspheres which are designed to expand in a specified temperature range, thereby debonding the coating compositions from a substrate. Adhesive compositions are overlaid on the debonding coating and are subsequently debonded from the substrate along with the debondable coating composition.

Abstract: Provided herein are stretchable conductive inks consisting of a continuous polymer phase with dispersed silver flakes and a low melting metal or alloy, wherein initial resistivity is measured before elongation and the resistivity of the stretchable conductive ink composition is less than 10 times the initial resistivity at 50% elongation.

Abstract: A light-colored polycarboxylated polysaccharide tanning agent, and a preparation method and use thereof are provided. The light-colored polycarboxylated polysaccharide tanning agent includes the following raw materials: a polysaccharide, an organic solvent, a catalyst, and hydrogen peroxide. Based on a weight of the polysaccharide, a weight of the organic solvent accounts for 1 wt % to 15 wt %, a weight of the catalyst accounts for 0.05 wt % to 2 wt %, and a weight of the hydrogen peroxide accounts for 30 wt % to 80 wt %. The preparation method provided by the present disclosure adopts a two-phase solution system. Compared with the existing preparation technologies, the preparation method of the present disclosure can efficiently extract and remove colored substances produced during an oxidation process, and can timely block a polymerization reaction of the colored substances with an oxidized polysaccharide, such as to significantly reduce a chromaticity of an oxidized product.

Abstract: Disclosed herein are stretchable conductive ink compositions comprising a polymer, conductive flake, an additive, and optionally conductive beads, wherein the initial resistivity is measured before elongation, and wherein the resistivity at 50% elongation is about 10 times or less of the initial resistivity.

Abstract: Disclosed is an estimation method for a whole life cycle cost of a power battery in echelon utilization. In this method, echelon utilization grades are established for the power battery according to an SOH of the power battery; a whole battery capacity model is constructed corresponding to the echelon utilization grades; a cost model is constructed corresponding to the echelon utilization grades; and a variation trend of the whole life cycle cost of the power battery is estimated according to the echelon utilization grades for the power battery, the power battery capacity model and the cost model, and a result of estimation is outputted.

Abstract: A light-colored polycarboxylated polysaccharide tanning agent, and a preparation method and use thereof are provided. The light-colored polycarboxylated polysaccharide tanning agent includes the following raw materials: a polysaccharide, an organic solvent, a catalyst, and hydrogen peroxide. Based on a weight of the polysaccharide, a weight of the organic solvent accounts for 1 wt % to 15 wt %, a weight of the catalyst accounts for 0.05 wt % to 2 wt %, and a weight of the hydrogen peroxide accounts for 30 wt % to 80 wt %. The preparation method provided by the present disclosure adopts a two-phase solution system. Compared with the existing preparation technologies, the preparation method of the present disclosure can efficiently extract and remove colored substances produced during an oxidation process, and can timely block a polymerization reaction of the colored substances with an oxidized polysaccharide, such as to significantly reduce a chromaticity of an oxidized product.

Abstract: Provided herein are metal conductive compositions with improved conductivity. The improved conductivity is attributable to the addition of a sintering agent and a polymer emulsion.

Abstract: Disclosed is a magnetic photoacoustic composite non destructive testing device for a power transmission line of a photovoltaic grid based on a corona effect. The device may include a mechanical structure part and a data processing part. The mechanical structure part may include a shielding shell and mounting bases, shielding bodies are mounted on two sides of the shielding shell, a top of the shielding shell is provided with an upper cover, two sides under the upper cover are provided with the mounting base respectively, and the two mounting bases are located above the shielding bodies respectively. The data processing part may include a pair of optical sensing modules, a pair of magnetic sensing modules, an acoustic sensing module, a humidity sensing module, a micro-processor, a signal conditioning and transmission unit and an internal power supply management module.

Abstract: Disclosed herein are stretchable conductive ink compositions comprising a polymer, conductive flake, an additive, and optionally conductive beads, wherein the initial resistivity is measured before elongation, and wherein the resistivity at 50% elongation is about 10 times or less of the initial resistivity.

Abstract: Disclosed is an estimation method for a whole life cycle cost of a power battery in echelon utilization. In this method, echelon utilization grades are established for the power battery according to an SOH of the power battery; a whole battery capacity model is constructed corresponding to the echelon utilization grades; a cost model is constructed corresponding to the echelon utilization grades; and a variation trend of the whole life cycle cost of the power battery is estimated according to the echelon utilization grades for the power battery, the power battery capacity model and the cost model, and a result of estimation is outputted.

Abstract: Provided herein are stretchable conductive inks consisting of a continuous polymer phase with dispersed silver flakes and a low melting metal or alloy, wherein initial resistivity is measured before elongation and the resistivity of the stretchable conductive ink composition is less than 10 times the initial resistivity at 50% elongation.

Abstract: Disclosed herein are electrically conductive ink compositions with high conductivity at a low conductive filler loading, the composition comprising a polymer, a monomer, an initiator or catalyst and conductive filler flakes, optionally the composition can include conductive or non-conductive beads, wherein after cure the monomer and polymer each form a separate phase.