Patents by Inventor Wenhua Zhang

Wenhua Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240131086
    Abstract: The present disclosure provides use of Clostridium ghonii combined with a tumor angiogenesis inhibitor in preparing a pharmaceutical product for treating a tumor. The present disclosure further provides a drug for treating a tumor, where the drug includes active ingredients of Clostridium ghonii and a tumor angiogenesis inhibitor.
    Type: Application
    Filed: October 9, 2022
    Publication date: April 25, 2024
    Inventors: Yong Wang, Yuanyuan Liu, Wenhua Zhang, Yanqiu Xing, Shaopeng Wang, Dan Wang, Hong Zhu, Xinglu Xu, Shengbiao Jiang, Xiaonan Li, Jiahui Zheng, Rong Zhang, Dongxia Yang, Yuxia Gao, Shili Shao, Ting Han
  • Publication number: 20240115627
    Abstract: The present disclosure relates to use of a Clostridium ghonii spore combined with pembrolizumab in cancer treatment. It is found for the first time that the Clostridium ghonii spore combined with pembrolizumab can significantly improve a curative effect of colon cancer and reduce a dose of the pembrolizumab, and thus is efficient and low-toxic. Oncolysis by Clostridium ghonii can affect immunogenicity of a tumor microenvironment (TME) by various ways, converts an immunosuppressive state of the TME into an immune-activated state, adjusts the immunosuppressive TME, and breaks an immune tolerance. An optimal combination of the Clostridium ghonii spore and the pembrolizumab thoroughly removes about 20% of mouse tumor tissues. A benefit range of patients with tumors treated by a PD-1 antibody is expanded. The combination even has an obvious curative effect on patients failed the treatment by the PD-1 antibody.
    Type: Application
    Filed: October 9, 2022
    Publication date: April 11, 2024
    Inventors: Yong Wang, Hong Zhu, Wenhua Zhang, Yanqiu Xing, Dan Wang, Yuanyuan Liu, Shaopeng Wang, Jiahui Zheng, Rong Zhang, Xiaonan Li, Xinglu Xu, Shengbiao Jiang, Lichao Xing, Yuxia Gao, Shili Shao, Ting Han
  • Publication number: 20240026168
    Abstract: Curable heat-expanding debondable coating compositions for use as a pre-coating or surface preparation in conjunction with adhesive composition. The debondable coating compositions include heat-expandable microspheres which are designed to expand in a specified temperature range, thereby debonding the coating compositions from a substrate. Adhesive compositions are overlaid on the debonding coating and are subsequently debonded from the substrate along with the debondable coating composition.
    Type: Application
    Filed: September 25, 2023
    Publication date: January 25, 2024
    Inventors: Wenhua Zhang, Richard Corrao, Ling Li
  • Patent number: 11840634
    Abstract: Provided herein are stretchable conductive inks consisting of a continuous polymer phase with dispersed silver flakes and a low melting metal or alloy, wherein initial resistivity is measured before elongation and the resistivity of the stretchable conductive ink composition is less than 10 times the initial resistivity at 50% elongation.
    Type: Grant
    Filed: June 28, 2021
    Date of Patent: December 12, 2023
    Assignee: HENKEL AG & CO, KGaA
    Inventors: Robert P. Cross, Bahram Issari, Wenhua Zhang, Lynnette M. Hurlburt, Jiangbo Ouyang, Rudolf Oldenzijl, Inge van der Meulen
  • Patent number: 11834724
    Abstract: A light-colored polycarboxylated polysaccharide tanning agent, and a preparation method and use thereof are provided. The light-colored polycarboxylated polysaccharide tanning agent includes the following raw materials: a polysaccharide, an organic solvent, a catalyst, and hydrogen peroxide. Based on a weight of the polysaccharide, a weight of the organic solvent accounts for 1 wt % to 15 wt %, a weight of the catalyst accounts for 0.05 wt % to 2 wt %, and a weight of the hydrogen peroxide accounts for 30 wt % to 80 wt %. The preparation method provided by the present disclosure adopts a two-phase solution system. Compared with the existing preparation technologies, the preparation method of the present disclosure can efficiently extract and remove colored substances produced during an oxidation process, and can timely block a polymerization reaction of the colored substances with an oxidized polysaccharide, such as to significantly reduce a chromaticity of an oxidized product.
    Type: Grant
    Filed: March 7, 2022
    Date of Patent: December 5, 2023
    Assignee: SICHUAN UNIVERSITY
    Inventors: Yue Yu, Yanan Wang, Bi Shi, Xueru Guo, Jianfei Zhou, Yunhang Zeng, Wenhua Zhang, Mingrong Cao
  • Patent number: 11814530
    Abstract: Disclosed herein are stretchable conductive ink compositions comprising a polymer, conductive flake, an additive, and optionally conductive beads, wherein the initial resistivity is measured before elongation, and wherein the resistivity at 50% elongation is about 10 times or less of the initial resistivity.
    Type: Grant
    Filed: July 8, 2021
    Date of Patent: November 14, 2023
    Assignee: HENKEL AG & CO, KGaA
    Inventors: Robert P. Cross, Wenhua Zhang, Zhan Yang, Jiangbo Ouyang, Yu Chen, Lynnette M. Hurlburt, Darel L. Gustafson
  • Patent number: 11416899
    Abstract: Disclosed is an estimation method for a whole life cycle cost of a power battery in echelon utilization. In this method, echelon utilization grades are established for the power battery according to an SOH of the power battery; a whole battery capacity model is constructed corresponding to the echelon utilization grades; a cost model is constructed corresponding to the echelon utilization grades; and a variation trend of the whole life cycle cost of the power battery is estimated according to the echelon utilization grades for the power battery, the power battery capacity model and the cost model, and a result of estimation is outputted.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: August 16, 2022
    Assignees: STATE GRID JIANGXI ELECTRIC POWER COMPANY LIMITED RESEARCH INSTITUTE, STATE GRID CORPORATION OF CHINA, NANCHANG KECHEN ELECTRIC POWER TEST AND RESEARCH CO., LTD, NANCHANG INSTITUTE OF TECHNOLOGY
    Inventors: Ping Liu, Wenhua Zhang, Rui Xu, Fayuan Wu, Yongqiang Deng, Xiaomin Dai, Jinhui Tang, Hongxia Xiao
  • Publication number: 20220251672
    Abstract: A light-colored polycarboxylated polysaccharide tanning agent, and a preparation method and use thereof are provided. The light-colored polycarboxylated polysaccharide tanning agent includes the following raw materials: a polysaccharide, an organic solvent, a catalyst, and hydrogen peroxide. Based on a weight of the polysaccharide, a weight of the organic solvent accounts for 1 wt % to 15 wt %, a weight of the catalyst accounts for 0.05 wt % to 2 wt %, and a weight of the hydrogen peroxide accounts for 30 wt % to 80 wt %. The preparation method provided by the present disclosure adopts a two-phase solution system. Compared with the existing preparation technologies, the preparation method of the present disclosure can efficiently extract and remove colored substances produced during an oxidation process, and can timely block a polymerization reaction of the colored substances with an oxidized polysaccharide, such as to significantly reduce a chromaticity of an oxidized product.
    Type: Application
    Filed: March 7, 2022
    Publication date: August 11, 2022
    Applicant: SICHUAN UNIVERSITY
    Inventors: Yue YU, Yanan WANG, Bi SHI, Xueru GUO, Jianfei ZHOU, Yunhang ZENG, Wenhua ZHANG, Mingrong CAO
  • Patent number: 11339304
    Abstract: Provided herein are metal conductive compositions with improved conductivity. The improved conductivity is attributable to the addition of a sintering agent and a polymer emulsion.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: May 24, 2022
    Assignee: Henkel AG & Co. KGaA
    Inventors: Wenhua Zhang, Qinyan Zhu, John G. Woods, Hong (Dorothy) Jiang, Junjun Wu, Mark Jason
  • Patent number: 11287459
    Abstract: Disclosed is a magnetic photoacoustic composite non destructive testing device for a power transmission line of a photovoltaic grid based on a corona effect. The device may include a mechanical structure part and a data processing part. The mechanical structure part may include a shielding shell and mounting bases, shielding bodies are mounted on two sides of the shielding shell, a top of the shielding shell is provided with an upper cover, two sides under the upper cover are provided with the mounting base respectively, and the two mounting bases are located above the shielding bodies respectively. The data processing part may include a pair of optical sensing modules, a pair of magnetic sensing modules, an acoustic sensing module, a humidity sensing module, a micro-processor, a signal conditioning and transmission unit and an internal power supply management module.
    Type: Grant
    Filed: July 29, 2020
    Date of Patent: March 29, 2022
    Assignee: North University of China
    Inventors: Yifeng Ren, Changxin Chen, Junmei Zhao, Shuncai Yao, Wenhua Zhang, Dongxing Pei, Tiehua Ma
  • Publication number: 20210340398
    Abstract: Disclosed herein are stretchable conductive ink compositions comprising a polymer, conductive flake, an additive, and optionally conductive beads, wherein the initial resistivity is measured before elongation, and wherein the resistivity at 50% elongation is about 10 times or less of the initial resistivity.
    Type: Application
    Filed: July 8, 2021
    Publication date: November 4, 2021
    Inventors: Robert P. CROSS, Wenhua ZHANG, Zhan YANG, Jiangbo OUYANG, Yu CHEN, Lynnette M. HURLBURT, Darel L. GUSTAFSON
  • Publication number: 20210334860
    Abstract: Disclosed is an estimation method for a whole life cycle cost of a power battery in echelon utilization. In this method, echelon utilization grades are established for the power battery according to an SOH of the power battery; a whole battery capacity model is constructed corresponding to the echelon utilization grades; a cost model is constructed corresponding to the echelon utilization grades; and a variation trend of the whole life cycle cost of the power battery is estimated according to the echelon utilization grades for the power battery, the power battery capacity model and the cost model, and a result of estimation is outputted.
    Type: Application
    Filed: January 8, 2019
    Publication date: October 28, 2021
    Applicants: STATE GRID JIANGXI ELECTRIC POWER COMPANY LIMITED RESEARCH INSTITUTE, STATE GRID CORPORATION OF CHINA, NANCHANG KECHEN ELECTRIC POWER TEST AND RESEARCH CO., LTD, NANCHANG INSTITUTE OF TECHNOLOGY
    Inventors: Ping LIU, Wenhua ZHANG, Rui XU, Fayuan WU, Yongqiang DENG, Xiaomin DAI, Jinhui TANG, Hongxia XIAO
  • Publication number: 20210324219
    Abstract: Provided herein are stretchable conductive inks consisting of a continuous polymer phase with dispersed silver flakes and a low melting metal or alloy, wherein initial resistivity is measured before elongation and the resistivity of the stretchable conductive ink composition is less than 10 times the initial resistivity at 50% elongation.
    Type: Application
    Filed: June 28, 2021
    Publication date: October 21, 2021
    Inventors: Robert P. Cross, Bahram lssari, Wenhua Zhang, Lynnette M. Hurlburt, Jiangbo Ouyang, Rudolf Oldenzijl, Inge van der Meulen
  • Publication number: 20210206988
    Abstract: Disclosed herein are electrically conductive ink compositions with high conductivity at a low conductive filler loading, the composition comprising a polymer, a monomer, an initiator or catalyst and conductive filler flakes, optionally the composition can include conductive or non-conductive beads, wherein after cure the monomer and polymer each form a separate phase.
    Type: Application
    Filed: March 23, 2021
    Publication date: July 8, 2021
    Inventors: Yu CHEN, Wenhua Zhang, Darel Gustafson, Robert P. Cross
  • Publication number: 20210033658
    Abstract: Disclosed is a magnetic photoacoustic composite non destructive testing device for a power transmission line of a photovoltaic grid based on a corona effect. The device may include a mechanical structure part and a data processing part. The mechanical structure part may include a shielding shell and mounting bases, shielding bodies are mounted on two sides of the shielding shell, a top of the shielding shell is provided with an upper cover, two sides under the upper cover are provided with the mounting base respectively, and the two mounting bases are located above the shielding bodies respectively. The data processing part may include a pair of optical sensing modules, a pair of magnetic sensing modules, an acoustic sensing module, a humidity sensing module, a micro-processor, a signal conditioning and transmission unit and an internal power supply management module.
    Type: Application
    Filed: July 29, 2020
    Publication date: February 4, 2021
    Inventors: Yifeng REN, Changxin CHEN, Junmei ZHAO, Shuncai YAO, Wenhua ZHANG, Dongxing PEI, Tiehua MA
  • Patent number: 10680155
    Abstract: A cross-plane flexible micro-TEG with hundreds of pairs of thermoelectric pillars formed via electroplating, microfabrication, and substrate transferring processes is provided herein. Typically, fabrication is conducted on a Si substrate, which can be easily realized by commercial production line. The fabricated micro-TEG transferred to the flexible layer from the Si substrate. Fabrication methods provided herein allow fabrication of main TEG components including bottom interconnectors, thermoelectric pillars, and top interconnectors by electroplating. Such flexible micro-TEGs provide high output power density due to high density of thermoelectric pillars and very low internal resistance of electroplated components. The flexible micro-TEG can achieve a power per unit area of 4.5 mW cm?2 at a temperature difference of ˜50 K, which is comparable to performance of flexible TEGs developed by screen printing.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: June 9, 2020
    Assignee: The Chinese University of Hong Kong
    Inventors: Wenhua Zhang, Dongyan Xu
  • Patent number: 10392543
    Abstract: Disclosed is a highly fluorinated silicone resin and a method for making the same. The silicone resin includes M, T, optionally D and optionally Q type monomers and is crosslinkable. The resin has a fluorine content of at least 55 weight percent and a very low refractive index of less than 1.4. The resin is formed in a one step process and requires use of very specific solvents. Preferably the resin includes a first T type monomer having a fluoroalkane group to provide the fluorine to the resin. Preferably the resin includes a second T type monomer having a (meth)acryloyl function to enable cross-linking. The resin forms an effective liquid optically clear adhesive. The resin can be further combined with highly fluorinated (meth)acrylate monomers or perfluoro polyethers to provide even lower refractive indexes and improved adhesive properties.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: August 27, 2019
    Assignee: Henkel IP & Holding GmbH
    Inventors: Bahram Issari, Wenhua Zhang, John G. Woods, Shengqian Kong, Yayun Liu, Jiangbo Ouyang, Li Kang
  • Patent number: 10322926
    Abstract: A structure for a MEMS device includes a MEMS layer comprising a mass portion and a spring portion, a substrate coupled to the MEMS layer, wherein the substrate comprises a planar region and an stopper region, wherein the MEMS device and the substrate are oriented in a plurality of relative orientations in response to an external force, wherein the spring portion and the stopper region are configured to disengagingly impact when the external force exceeds a first threshold force, wherein the mass portion and the planar region are configured to disengagingly impact when the external force exceeds a second threshold force, and wherein the second threshold force exceeds the first threshold force.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: June 18, 2019
    Assignee: mCube, Inc.
    Inventors: Sudheer Sridharamurthy, Te-Hsi Terrence Lee, Wenhua Zhang
  • Publication number: 20190169478
    Abstract: Dual-cure compositions for use in high temperature adhesive applications, and particularly for temporarily adhesively attaching one substrate to another substrate, are provided. These dual-cure adhesives are silicone-based compositions that can be B-staged by exposure UV radiation to provide initial green strength, followed by a C-stage cure to give adhesives that can survive high temperature processes above 200° C., especially above 300° C., yet easy to debond afterwards to allow separation of the top and bottom substrates.
    Type: Application
    Filed: June 5, 2018
    Publication date: June 6, 2019
    Inventors: Shengqian KONG, Yayun LIU, Wenhua ZHANG, Stephen HYNES, John G. WOODS, Jiangbo OUYANG, Chunyu SUN, Bahram ISSARI
  • Patent number: 10280349
    Abstract: The present invention relates to one-component UV and thermal curable temporary adhesives for use in high temperature applications, and particularly to adhesives for the temporary attachment of one substrate to another substrate, the adhesives comprising (i) the partial hydrosilylation reaction product of the reaction between the vinyl groups on 1,3,5,7-tetravinyl-1,3,5,7-tetramethylcyclotetrasiloxane and the terminal Si—H hydrogens on a silane or siloxane having terminal Si—H hydrogens, and (ii) a photo and/or thermal radical cure initiator. Also encompassed are assemblies including such an adhesive and methods of using the adhesives.
    Type: Grant
    Filed: December 7, 2016
    Date of Patent: May 7, 2019
    Assignees: Henkel AG & Co. KGaA, Henkel IP & Holding GmbH
    Inventors: Stephen Hynes, Chunyu Sun, Jiangbo Ouyang, John Gregory Woods, Bahram Issari, Shengqian Kong, Yayun Liu, Wenhua Zhang