Abstract: A computing system is provided for modeling a deployment of heterogeneous memory on a server network. The computing system receives a user input of parameters including a memory ratio of local memory to heterogeneous memory in each server, a first relative throughput when an entire dataset is in local memory on a server, and a second relative throughput when the entire dataset is in heterogeneous memory on the server. Based on these parameters, the system determines a server ratio of a number of servers in an enhanced cluster with heterogeneous memory to a number of servers in a baseline cluster without heterogeneous memory, where the enhanced cluster and the baseline cluster deliver equivalent data throughput performance. Based on the parameters and the server ratio, a server network design is generated and outputted.

Abstract: A mounting bracket includes a bracket body, a locking assembly and support foot. The bracket body is configured for component installation. The locking assembly is arranged on the bracket body, and the support foot is arranged on the bracket body. The support foot is slide along the up and down direction of the bracket body, and the locking assembly is configured to lock the support foot at a preset position. Through the above structure, the support foot is installed on the ground and used to support the bracket body, and the locking assembly locks the support foot at a preset position to correspondingly adjust the height of the bracket body from the ground, so as to adjust the suspension height of the components installed on the bracket body.

Abstract: A regulating device for regulating water consumption of a concealed water tank includes a water tank, a hinged base is fixedly arranged on the inner wall of the water tank, a water separator is hinged on the hinged base. A regulating mechanism is arranged between the hinged base and the water separator, and the regulating mechanism can drive the water separator to rotate and fix to divide the accommodation space of the water tank. Compared with the prior art, the regulating device realizes the variable volume of the water tank by regulating the rotation of the water separator through the regulating mechanism. The structure is simple and convenient for the later repair and maintenance of the water tank.

Abstract: The present disclosure includes compositions and methods for improved DNA amplification reactions. In particular, the present disclosure provides compositions and methods for hot-start PCR applications using DNA polymerase inhibitors that minimize non-specific DNA amplification by inactivating DNA polymerase at lower temperatures.

Abstract: Provided herein are surfactant compounds that can be used to aid in preparation of protein samples for analysis, for example by mass spectrometry.

Abstract: Disclosed are a method and device for winding a foil coil of a stereoscopic wound iron core transformer. The device includes a rotating assembly, a driving device and a plurality of loading assemblies; the rotating assembly is provided with a through hole matched with an iron core post, the rotating assembly is provided with a gear plate and a track ring around the through hole, and the gear plate and the track ring are fixedly connected by a fixing block; the loading assembly includes a cylinder and a tension device, and the cylinder is movably connected with the rotating assembly; and a driving end of the driving device is connected with the gear plate.

Abstract: A winding die is disclosed, including: a gear baffle, where a middle portion of the gear baffle is provided with a first opening for placing an iron core post, and the gear baffle is provided with a first surface; and a cylinder, where the cylinder is arranged on the first surface of the gear baffle and connected with the gear baffle. The middle portion of the gear baffle is provided with the first opening for placing the iron core post, the gear baffle is fixedly connected with the cylinder, an external device is connected with a gear, and the cylinder on the gear baffle is driven to rotate around the iron core post by pulling the gear, so that a foil or an insulating material on the cylinder can be wound on the iron core post, finally realizing a foil winding.

Abstract: A winding cylinder of a stereoscopic wound iron core transformer is disclosed, including an outer cylinder, an inner cylinder and a tension assembly. The outer cylinder is movably connected with the inner cylinder through a bearing assembly, and the outer cylinder rotatable around an axis of the inner cylinder. The tension assembly includes a screw, a spring and a connecting assembly. The connecting assembly includes a fixing portion, a friction portion and a transmission portion, the friction portion and the transmission portion are both arranged around the inner cylinder, and the transmission portion is fixedly connected with the outer cylinder. A side face of the inner cylinder is provided with a through hole, and the fixing portion penetrates through the through hole and is fixedly connected with the friction portion.

Abstract: Disclosed herein are compounds that can be used to selectively detect nitric oxide in samples. Also disclosed herein are compositions comprising the compounds and methods of detecting nitric oxide using the compounds.

Abstract: Described are coelenterazine analogues, methods for making the analogues, kits comprising the analogues, and methods of using the compounds for the detection of luminescence in luciferase-based assays.

Abstract: Provided herein are polysiloxane matrices and biocompatible films thereof for the detection of oxygen. In particular, oxygen-sensitive fluorophores embedded within polysiloxane matrices are utilized for detection of oxygen consumption rate in living cells.

Abstract: Conjugates comprise a drug or probe, a cell binding agent, and a quinone-containing linker. The quinone-containing linker may be reduced intracellularly to trigger release of the drug or probe. These conjugates may selectively deliver a drug or probe to a site of action of interest for local release of the active drug or probe.

Abstract: Compounds that may inhibit Oplophorus-derived luciferases are disclosed as well as compositions and kits comprising the compounds and methods of using the compounds.

Abstract: Provided herein are compounds, compositions, and methods for rapid isolation of nucleic acids from a sample.

Abstract: Provided herein multifunctional compounds that bind and modify nucleic acids, forming crosslinks between the nucleic acid strands. In particular embodiments, the multifunctional nucleic-acid binding/modifying compounds are selective for nucleic acids of non-viable cells and viruses (i.e., they are excluded from or degraded within viable cells and viruses), and therefore find use in methods for detecting or discriminating viable and non-viable cells/viruses and nucleic acids therefrom.

Abstract: Provided herein are compounds, compositions, systems, and methods for photoactivatable labeling, which can be actuated within biological systems. In particular, compounds disclosed herein include vinyl-extended-aryl azide moieties that undergo photoactivation to generate reactive intermediates, which can form covalent linkages with biomolecules. The photoactivation can be conducted by a variety of mechanisms including ultraviolet (UV) irradiation, visible light irradiation, or energy transfer (e.g., from a photocatalyst). The compounds also include functional moieties that provide useful functionalities, for example detection of biomolecules, such as fluorophores, capture elements (e.g., biotin), or reactive moieties (e.g., click handles) and bifunctional moieties comprising a bioactive compound and a detection/capture element.

Abstract: Disclosed herein are compounds that can be used to selectively detect superoxide in samples. Also disclosed herein are compositions comprising the compounds and methods of detecting superoxide using the compounds.

Abstract: Disclosed herein are functionalized oxazine dye compounds, compositions comprising the compounds, and methods of using the compounds, e.g., in nucleic acid amplification reactions. Also disclosed herein are labeled oligonucleotides and labeled nucleotide triphosphate compounds.

Abstract: An angle valve structure includes an angle valve body. The angle valve body is provided with a water inlet channel, a water outlet channel and an accommodation cavity. The accommodation cavity is rotationally provided with a valve core. One end of the valve core exposed outside the accommodation cavity is fixedly connected with a knob. The valve core is provided with a sealing block for sealing the water outlet channel when sealing. The valve core includes a main body part and an elastic arm whose one end is connected with the main body part. One side of the main body part is provided with a mounting slot for placing the sealing block, one side of the elastic arm is provided with an extrusion portion, and the other side of the elastic arm is provided with a contact portion against the sealing block after assembly.

Abstract: Described are coelenterazine analogues, methods for making the analogues, kits comprising the analogues, and methods of using the compounds for the detection of luminescence in luciferase-based assays.