Patents by Inventor Wenling Zhang

Wenling Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation method of rocuronium
    Patent number: 9067965
    Abstract: A method for preparing rocuronium is disclosed. 2?-(4-Morpholinyl)-16?-(1-pyrrolidinyl)-5?-androstan-3?-ol-17?-acetate is used as a starting material and is directly reacted with 3-bromopropene at ambient temperature to produce rocuronium.
    Type: Grant
    Filed: January 26, 2011
    Date of Patent: June 30, 2015
    Assignee: Zhejiang Huahai Pharmaceutical Co., Ltd.
    Inventors: Zhiwen Zeng, Wenling Zhang, Peng Wang, Xini Zhang
  • Method for purifying rocuronium bromide
    Patent number: 9024013
    Abstract: Provided is a method for purifying rocuronium bromide, which comprises: formulating crude rocuronium bromide to be purified into an aqueous solution, distilling off excess residue solvents at reduced pressure, absorbing by adding active carbon or silica gel, then filtrating, quick freezing the filtrate into ice, and then lyophilizing to obtain rocuronium bromide.
    Type: Grant
    Filed: April 25, 2011
    Date of Patent: May 5, 2015
    Assignee: Zhejiang Huahai Pharmaceutical Co., Ltd
    Inventors: Zhiwen Zeng, Peng Wang, Wenling Zhang, Xini Zhang
  • METHOD FOR PURIFYING ROCURONIUM BROMIDE
    Publication number: 20140200340
    Abstract: Provided is a method for purifying rocuronium bromide, which comprises: formulating crude rocuronium bromide to be purified into an aqueous solution, distilling off excess residue solvents at reduced pressure, absorbing by adding active carbon or silica gel, then filtrating, quick freezing the filtrate into ice, and then lyophilizing to obtain rocuronium bromide.
    Type: Application
    Filed: April 25, 2011
    Publication date: July 17, 2014
    Applicant: ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD.
    Inventors: Zhiwen Zeng, Peng Wang, Wenling Zhang, Xini Zhang
  • PREPARATION METHOD OF ROCURONIUM
    Publication number: 20130303753
    Abstract: A method for preparing rocuronium is disclosed. 2?-(4-Morpholinyl)-16?-(1-pyrrolidinyl)-5?-androstan-3?-ol-17?-acetate is used as a starting material and is directly reacted with 3-bromopropene at ambient temperature to produce rocuronium.
    Type: Application
    Filed: January 26, 2011
    Publication date: November 14, 2013
    Applicant: Zhejiang Huahai Pharmaceutical Co., Ltd.
    Inventors: Zhiwen Zeng, Wenling Zhang, Peng Wang, Xini Zhang