Patents by Inventor Wenqing Yao

Wenqing Yao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclopropylamines as LSD1 inhibitors
    Patent number: 10513493
    Abstract: The present invention is directed to cyclopropylamine derivatives which are LSD1 inhibitors useful in the treatment of diseases such as cancer.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: December 24, 2019
    Assignee: Incyte Corporation
    Inventors: Liangxing Wu, Chunhong He, Ding-Quan Qian, Bo Shen, Wenqing Yao
  • CARBOXAMIDE COMPOUNDS AND USES THEREOF
    Publication number: 20190382380
    Abstract: Disclosed are compounds of Formula (I?) methods of using the compounds for inhibiting HPK1 activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer.
    Type: Application
    Filed: February 19, 2019
    Publication date: December 19, 2019
    Inventors: Oleg Vechorkin, Jun Pan, Alexander Sokolsky, Evan Styduhar, Qinda Ye, Wenqing Yao
  • FUSED PYRIMIDINE DERIVATIVES AS A2A / A2B INHIBITORS
    Publication number: 20190375752
    Abstract: This application relates to compounds of Formula (I): or pharmaceutically acceptable salts thereof, which modulate the activity of adenosine receptors, such as subtypes A2A and A2B receptors, and are useful in the treatment of diseases related to the activity of adenosine receptors including, for example, cancer, inflammatory diseases, cardiovascular diseases, and neurodegenerative diseases.
    Type: Application
    Filed: May 17, 2019
    Publication date: December 12, 2019
    Inventors: Xiaozhao Wang, Heeoon Han, Matthew S. McCammant, Liangxing Wu, Wenqing Yao, Zhiyong Yu, Le Zhao
  • Webpage pre-reading method, apparatus and smart terminal
    Patent number: 10503710
    Abstract: A method is provided for webpage pre-reading. The method includes obtaining visiting information during a period of time for multiple webpages of each user from a plurality of users including a current user; determining respective similarity values between the current user and the plurality of users based on the visiting information; determining one or more most-similar users based on the similarity values; and when the current user is browsing a current webpage, predicting a target webpage to be accessed by the most-similar users as a target webpage for the current user and pre-reading the target webpage.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: December 10, 2019
    Assignee: GUANGZHOU UCWEB COMPUTER TECHNOLOGY CO., LTD
    Inventors: Jie Liang, Yuxin Jiang, Wenqing Yao, Huocheng Wu, Yanwei Xu
  • TRICYCLIC HETEROCYCLIC COMPOUNDS AS STING ACTIVATORS
    Publication number: 20190359608
    Abstract: The present application provides tricyclic heterocyclic compounds that activate the STING pathway to produce interferons, which are useful in the treatment of various diseases including infectious diseases and cancer.
    Type: Application
    Filed: May 24, 2019
    Publication date: November 28, 2019
    Inventors: Liangxing Wu, Neil Lajkiewicz, Yingda Ye, Zhenwu Li, Wenqing Yao
  • PYRAZOLOPYRIDINE COMPOUNDS AND USES THEREOF
    Publication number: 20190343814
    Abstract: Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting HPK1 activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer.
    Type: Application
    Filed: July 22, 2019
    Publication date: November 14, 2019
    Inventors: Alexander Sokolsky, Oleg Vechorkin, Kai Liu, Jun Pan, Wenqing Yao, Qinda Ye
  • HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS
    Publication number: 20190345170
    Abstract: Disclosed are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections.
    Type: Application
    Filed: May 10, 2019
    Publication date: November 14, 2019
    Inventors: Liangxing Wu, Kaijiong Xiao, Wenqing Yao
  • Imidazo[1,2-B][1,2,4]triazines as c-Met inhibitors
    Patent number: 10472367
    Abstract: The present invention relates to imidazo[1,2-b][1,2,4]triazines that are inhibitors of c-Met and are useful in the treatment of c-Met associated diseases including cancer.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: November 12, 2019
    Assignees: INCYTE INCORPORATION, INCYTE HOLDINGS CORPORATION
    Inventors: Jincong Zhuo, Chunhong He, Wenqing Yao
  • Bicyclic heterocycles as FGFR inhibitors
    Patent number: 10450313
    Abstract: The present invention relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of one or more FGFR enzymes and are useful in the treatment of FGFR-associated diseases such as cancer.
    Type: Grant
    Filed: July 2, 2018
    Date of Patent: October 22, 2019
    Assignees: Incyte Holdings Corporation, Incyte Corporation
    Inventors: Liang Lu, Wenqing Yao, Chunhong He, Fenglei Zhang
  • PYRAZOLOPYRIDINE COMPOUNDS AND USES THEREOF
    Publication number: 20190315743
    Abstract: Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting HPK1 activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer.
    Type: Application
    Filed: June 27, 2019
    Publication date: October 17, 2019
    Inventors: Kai Liu, Jun Pan, Alexander Sokolsky, Oleg Vechorkin, Hai Fen Ye, Qinda Ye, Wenqing Yao
  • BENZIMIDAZOLE AND INDOLE COMPOUNDS AND USES THEREOF
    Publication number: 20190315717
    Abstract: Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting HPK1 activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer.
    Type: Application
    Filed: April 12, 2019
    Publication date: October 17, 2019
    Inventors: Joshua Hummel, Minh Nguyen, Alexander Sokolsky, Oleg Vechorkin, Qinda Ye, Wenqing Yao
  • Pyrazolopyridine compounds and uses thereof
    Patent number: 10435405
    Abstract: Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting HPK1 activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: October 8, 2019
    Assignee: Incyte Corporation
    Inventors: Oleg Vechorkin, Kai Liu, Alexander Sokolsky, Anlai Wang, Hai Fen Ye, Qinda Ye, Wenqing Yao
  • HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS
    Publication number: 20190300524
    Abstract: Disclosed are compounds of Formula (I?), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections.
    Type: Application
    Filed: March 29, 2019
    Publication date: October 3, 2019
    Inventors: Liangxing Wu, Jingwei Li, Wenqing Yao
  • IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES AS A2A / A2B INHIBITORS
    Publication number: 20190292188
    Abstract: This application relates to compounds of Formula (I): or pharmaceutically acceptable salts or stereoisomers thereof, which modulate the activity of adenosine receptors, such as subtypes A2A and A2B receptors, and are useful in the treatment of diseases related to the activity of adenosine receptors including, for example, cancer, inflammatory diseases, cardiovascular diseases, and neurodegenerative diseases.
    Type: Application
    Filed: February 26, 2019
    Publication date: September 26, 2019
    Inventors: Xiaozhao Wang, Pei Gan, Heeoon Han, Taisheng Huang, Matthew S. McCammant, Chao Qi, Ding-Quan Qian, Liangxing Wu, Wenqing Yao, Zhiyong Yu, Fenglei Zhang
  • BICYCLIC HETEROCYCLES AS FGFR4 INHIBITORS
    Publication number: 20190284187
    Abstract: The present invention relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR4 enzyme and are useful in the treatment of FGFR4-associated diseases such as cancer.
    Type: Application
    Filed: April 23, 2019
    Publication date: September 19, 2019
    Inventors: Liangxing Wu, Liang Lu, Ding-Quan Qian, Bo Shen, Wenqing Yao
  • BICYCLIC HETEROCYCLES AS FGFR4 INHIBITORS
    Publication number: 20190269693
    Abstract: The present disclosure relates to bicyclic heterocycles of Formula (I?), and pharmaceutical compositions of the same, that are inhibitors of the FGFR3 and/or FGFR4 enzyme and are useful in the treatment of FGFR-associated diseases.
    Type: Application
    Filed: February 15, 2019
    Publication date: September 5, 2019
    Inventors: Liang Lu, Bo Shen, Alexander Sokolsky, Xiaozhao Wang, Liangxing Wu, Wenqing Yao, Yingda Ye
  • INDAZOLE COMPOUNDS AND USES THEREOF
    Publication number: 20190256500
    Abstract: Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting HPK1 activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer.
    Type: Application
    Filed: February 19, 2019
    Publication date: August 22, 2019
    Inventors: Oleg Vechorkin, Alexander Sokolsky, Qinda Ye, Wenqing Yao
  • INDAZOLE COMPOUNDS AND USES THEREOF
    Publication number: 20190256520
    Abstract: Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting HPK1 activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer.
    Type: Application
    Filed: February 19, 2019
    Publication date: August 22, 2019
    Inventors: Alexander Sokolsky, Oleg Vechorkin, Anlai Wang, Qinda Ye, Wenqing Yao
  • Webpage pre-reading method, apparatus and smart terminal device
    Patent number: 10389826
    Abstract: The present invention provides a webpage pre-reading method, apparatus and a smart terminal device. The webpage pre-reading method includes: acquiring information of one or more users accessing multiple webpages within a first period of time; determining click paths through each of which a second webpage is clicked and entered from a first webpage and the number of clicks thereof; determining a first confidence value of each click path; generating a first pre-reading list including the click paths based on the first confidence values; and querying for a click path of a currently browsed webpage from the first pre-reading list so as to pre-read data of a corresponding target webpage to be browsed.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: August 20, 2019
    Assignee: Guangzhou UCWeb Computer Technology Co., Ltd.
    Inventors: Jie Liang, Yuxin Jiang, Wenqing Yao, Huocheng Wu, Yanwei Xu, Yanjun Liang, Yan Lu, Jiawei Qiu
  • SUBSTITUTED IMIDAZOPYRIDAZINES AND BENZIMIDAZOLES AS INHIBITORS OF FGFR3
    Publication number: 20190240220
    Abstract: The present invention relates to substituted imidazopyridazines and substituted benzimidazoles, as well as pharmaceutical compositions comprising the same, which are FGFR3 inhibitors useful in the treatment of cancer and other diseases.
    Type: Application
    Filed: January 2, 2019
    Publication date: August 8, 2019
    Inventors: Wenqing Yao, Colin Zhang, Meizhong Xu, Jincong Zhuo, Chunhong He