Patents by Inventor Wenyan Wang

Wenyan Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040157309
    Abstract: The present invention discloses purified polypeptides that comprise an active ADAM33 catalytic domain. In addition, the present invention discloses nucleic acids that encode the polypeptides of the present invention. The present invention also discloses methods of growing X-ray diffractable crystals of polypeptides comprising the active ADAM33 catalytic domain. The present invention further discloses a crystalline form of a catalytic domain of ADAM33. In addition, the present invention discloses methods of using the X-ray diffractable crystals of ADAM33 in structure based drug design to identify compounds that can modulate the enzymatic activity of ADAM33. The present invention also discloses methods of treating respiratory disorders by administering therapeutic amounts of the ADAM33 catalytic domain.
    Type: Application
    Filed: December 19, 2003
    Publication date: August 12, 2004
    Applicant: Schering Corporation
    Inventors: Peter Orth, Paul Reichert, Vincent S. Madison, Wenyan Wang, Jun Zou
  • Publication number: 20040151715
    Abstract: The present invention discloses purified polypeptides that comprise an active ADAM33 catalytic domain. In addition, the present invention discloses nucleic acids that encode the polypeptides of the present invention. The present invention also discloses methods of growing X-ray diffractable crystals of polypeptides comprising the active ADAM33 catalytic domain. In addition, the present invention discloses methods of using the X-ray diffractable crystals of ADAM33 in structure-based drug design to identify compounds that can modulate the enzymatic activity of ADAM33. The present invention also discloses methods of treating respiratory disorders by administering therapeutic amounts of the ADAM33 catalytic domain.
    Type: Application
    Filed: December 19, 2003
    Publication date: August 5, 2004
    Applicant: Schering Corporation
    Inventors: Wenyan Wang, Hung V. Le, Jian-Jun Liu, Vincent S. Madison, Winifred W. Prosise, Shahriar Shane Taremi, Li Xiao, Jun Zou
  • Publication number: 20040014194
    Abstract: The present invention relates to the expression, purification and crystallization of glycosylated &bgr;-secretase protein and a complex thereof. The crystals of the invention are useful, inter alia, for determining the three-dimensional structure of &bgr;-secretase and of other, related proteins.
    Type: Application
    Filed: March 26, 2003
    Publication date: January 22, 2004
    Applicant: Schering Corporation
    Inventors: Brian M. Beyer, Gerald S. Hammond, Paul Reichert, Corey Strickland, Wenyan Wang, Patricia C. Weber, Gwendolyn Tse Wong, Lili Zhang