Patents by Inventor Wenyuan QI
Wenyuan QI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220335664Abstract: A guided pairing method includes generating a singles list by detecting a plurality of singles at a plurality of detector elements in a detector array, the plurality of singles falling within a plurality of detection windows; for each detection window of the plurality of detection windows in the singles list having exactly two singles of the plurality of singles, determining the line of responses (LORs) for each of the two singles of the plurality of singles; for each detection window of the plurality of detection windows in the singles list having more than two singles of the plurality of singles, determining all coincidences possible based on the more than two singles; generating a weight for said each coincidence of the coincidences based on the determined LORs for said each of the two singles of the plurality of singles; and pairing the more than two singles based on the generated weight for said each coincidence of the coincidences.Type: ApplicationFiled: April 14, 2021Publication date: October 20, 2022Applicant: CANON MEDICAL SYSTEMS CORPORATIONInventors: Wenyuan QI, Yi QIANG, Peng PENG, Evren ASMA, Jeffrey KOLTHAMMER
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Patent number: 11369333Abstract: The present disclosure provides a method and apparatus for detecting a dose distribution of an article. The method includes performing a fluoroscopy scanning on the article to be detected, to obtain mass data per unit area or unit volume for each point of the article to be detected; obtaining corresponding dose distribution data based on the mass data per unit area or unit volume and a preset mapping model, wherein the preset mapping model includes a mapping relationship between mass per unit area or unit volume and the dose distribution of the article under irradiation of a preset amount of energy; and matching the dose distribution data with a fluoroscopy image of the article to be detected, to generate and display a radiation image.Type: GrantFiled: June 24, 2020Date of Patent: June 28, 2022Assignees: Nuctech Company Limited, Nucway Company Limited, Tsinghua UniversityInventors: Zhiqiang Chen, Yuanjing Li, Zhiwei Han, Guang Yang, Huaili Qin, Wenyuan Qi, Shan Kuang, Aifeng Liang, Yanqin Liu
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Patent number: 11332069Abstract: In various embodiments, methods, systems, and vehicle apparatuses are provided. The method includes receiving, via an interface of the V2X enabled safety triangle warning reflector, vehicle information before deployment for storing the vehicle information in a memory disposed locally at the V2X enabled safety triangle warning reflector for subsequent use at the deployment; generating, by a processor chip in communication with the memory, a failure message associated with the vehicle failure based at least on the vehicle information contained locally in memory; and broadcasting, the failure message generated by the processor chip via a transmitter disposed of in the V2X enable safety triangle warning reflector during a vehicle failure, wherein the failure message is broadcasted in a surrounding area of the failure vehicle on a set of multiple different channels including cloud, infrastructure and personal communication service (PCS) channels to entities that provide traffic and vehicle control.Type: GrantFiled: March 2, 2021Date of Patent: May 17, 2022Assignee: GM GLOBAL TECHNOLOGY OPERATIONS LLCInventor: Wenyuan Qi
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Publication number: 20220113437Abstract: A method of normalizing detector elements in an imaging system is described herein. The method includes a line source that is easier to handle for a user, and decouples the normalization of the detector elements into a transaxial domain and an axial domain in order to isolate errors due to positioning of the line source. Additional simulations are performed to augment the real scanner normalization. A simulation of a simulated line source closely matching the real line source can be performed to isolate errors due to physical properties of the crystals and position of the crystals in the system, wherein the simulated detector crystals are otherwise modeled uniformly. A simulation of a simulated cylinder source can be performed to determine errors due to other effects stemming from gaps between the detector crystals.Type: ApplicationFiled: December 21, 2021Publication date: April 14, 2022Applicant: CANON MEDICAL SYSTEMS CORPORATIONInventors: Wenyuan QI, Yi QIANG, Evren ASMA, Xiaoli LI, Li YANG, Peng PENG, Jeffrey KOLTHAMMER
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Patent number: 11276209Abstract: The present disclosure relates to an apparatus for estimating scatter in positron emission tomography, comprising processing circuitry configured to acquire an emission map and an attenuation map, each representing an initial image reconstruction of a positron emission tomography scan, calculate, using a radiative transfer equation (RTE) method, a scatter source map of a subject of the positron emission tomography scan based on the emission map and the attenuation map, estimate, using the RTE method and based on the emission map, the attenuation map, and the scatter source map, scatter, and perform an iterative image reconstruction of the positron emission tomography scan based on the estimated scatter and raw data from the positron emission tomography scan of the subject.Type: GrantFiled: April 28, 2020Date of Patent: March 15, 2022Assignee: CANON MEDICAL SYSTEMS CORPORATIONInventors: Wenyuan Qi, Yujie Lu, Evren Asma, Yi Qiang, Jeffrey Kolthammer, Zhou Yu
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Patent number: 11249206Abstract: A method of normalizing detector elements in an imaging system is described herein. The method includes a line source that is easier to handle for a user, and decouples the normalization of the detector elements into a transaxial domain and an axial domain in order to isolate errors due to positioning of the line source. Additional simulations are performed to augment the real scanner normalization. A simulation of a simulated line source closely matching the real line source can be performed to isolate errors due to physical properties of the crystals and position of the crystals in the system, wherein the simulated detector crystals are otherwise modeled uniformly. A simulation of a simulated cylinder source can be performed to determine errors due to other effects stemming from gaps between the detector crystals.Type: GrantFiled: May 5, 2020Date of Patent: February 15, 2022Assignee: CANON MEDICAL SYSTEMS CORPORATIONInventors: Wenyuan Qi, Yi Qiang, Evren Asma, Xiaoli Li, Li Yang, Peng Peng, Jeffrey Kolthammer
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Patent number: 11250599Abstract: A method of imaging includes obtaining a plurality of dynamic sinograms, each dynamic sinogram representing detection events of gamma rays at a plurality of detector elements, summing the plurality of dynamic sinograms to generate an activity map based on a radioactivity level of the gamma rays; reconstructing, using the plurality of dynamic sinograms, a plurality of dynamic images, each of the plurality of dynamic images corresponding to one of the each of the plurality of dynamic sinograms, and generating, using the plurality of dynamic sinograms and the activity map, at least one parametric image.Type: GrantFiled: April 24, 2020Date of Patent: February 15, 2022Assignee: CANON MEDICAL SYSTEMS CORPORATIONInventors: Li Yang, Wenyuan Qi, Evren Asma
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Patent number: 11241211Abstract: A method and apparatus is provided to perform dead-time correction in a positron emission tomography (PET) by estimating a full singles spectrum using a scatter model. The scatter model can use a Monte Carlo method, a radiation transfer equation method, an artificial neural network, or an analytical expression. The scatter model simulates scatter based on an emission image/map and an attenuation image/map to estimate Compton scattering. In the full singles spectrum, the singles counts with energies less than 511 keV are determined from the simulated scatter. The attenuation image can be generated based on X-ray computed tomography or based on applying a joint-estimation to PET data.Type: GrantFiled: March 12, 2020Date of Patent: February 8, 2022Assignee: CANON MEDICAL SYSTEMS CORPORATIONInventors: Wenyuan Qi, Yi Qiang, Karthikayan Balakrishnan, Yujie Lu
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Publication number: 20210335022Abstract: A method of imaging includes obtaining a plurality of dynamic sinograms, each dynamic sinogram representing detection events of gamma rays at a plurality of detector elements, summing the plurality of dynamic sinograms to generate an activity map based on a radioactivity level of the gamma rays; reconstructing, using the plurality of dynamic sinograms, a plurality of dynamic images, each of the plurality of dynamic images corresponding to one of the each of the plurality of dynamic sinograms, and generating, using the plurality of dynamic sinograms and the activity map, at least one parametric image.Type: ApplicationFiled: April 24, 2020Publication date: October 28, 2021Applicant: CANON MEDICAL SYSTEMS CORPORATIONInventors: Li YANG, Wenyuan QI, Evren ASMA
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Publication number: 20210335023Abstract: The present disclosure relates to an apparatus for estimating scatter in positron emission tomography, comprising processing circuitry configured to acquire an emission map and an attenuation map, each representing an initial image reconstruction of a positron emission tomography scan, calculate, using a radiative transfer equation (RTE) method, a scatter source map of a subject of the positron emission tomography scan based on the emission map and the attenuation map, estimate, using the RTE method and based on the emission map, the attenuation map, and the scatter source map, scatter, and perform an iterative image reconstruction of the positron emission tomography scan based on the estimated scatter and raw data from the positron emission tomography scan of the subject.Type: ApplicationFiled: April 28, 2020Publication date: October 28, 2021Inventors: Wenyuan QI, Yujie LU, Evren ASMA, Yi QIANG, Jeffrey KOLTHAMMER, Zhou YU
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Publication number: 20210304457Abstract: To reduce the effect(s) caused by patient breathing and movement during PET data acquisition, an unsupervised non-rigid image registration framework using deep learning is used to produce motion vectors for motion correction. In one embodiment, a differentiable spatial transformer layer is used to warp the moving image to the fixed image and use a stacked structure for deformation field refinement. Estimated deformation fields can be incorporated into an iterative image reconstruction process to perform motion compensated PET image reconstruction. The described method and system, using simulation and clinical data, provide reduced error compared to at least one iterative image registration process.Type: ApplicationFiled: February 19, 2021Publication date: September 30, 2021Applicants: The Regents of the University of California, CANON MEDICAL SYSTEMS CORPORATIONInventors: Jinyi QI, Tiantian LI, Zhaoheng XIE, Wenyuan QI, Li YANG, Chung CHAN, Evren ASMA
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Publication number: 20210282732Abstract: A method and apparatus is provided to perform dead-time correction in a positron emission tomography (PET) by estimating a full singles spectrum using a scatter model. The scatter model can use a Monte Carlo method, a radiation transfer equation method, an artificial neural network, or an analytical expression. The scatter model simulates scatter based on an emission image/map and an attenuation image/map to estimate Compton scattering. In the full singles spectrum, the singles counts with energies less than 511 keV are determined from the simulated scatter. The attenuation image can be generated based on X-ray computed tomography or based on applying a joint-estimation to PET data.Type: ApplicationFiled: March 12, 2020Publication date: September 16, 2021Applicant: Canon Medical Systems CorporationInventors: Wenyuan QI, Yi Qiang, Karthikayan Balakrishnan, Yujie Lu
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Patent number: 11096633Abstract: A positron emission tomography scanner includes a plurality of gamma-ray detector rings that form a bore through which an imaging subject is translated, each of the plurality of gamma-ray detector rings being in a first axial position, and processing circuitry configured to receive attenuation data associated with a plurality of transaxial slices of the imaging subject, determine a second axial position of each of the plurality of gamma-ray detector rings based on the received attenuation data, and adjust a position of each of the plurality of gamma-ray detector rings from the first axial position to the second axial position. The processing circuitry may further be configured to calculate an attenuation metric based on the received attenuation data, and determine the second axial position such that the attenuation metric calculated for each pair of adjacent gamma-ray detector rings is equal.Type: GrantFiled: May 27, 2020Date of Patent: August 24, 2021Assignee: CANON MEDICAL SYSTEMS CORPORATIONInventors: Wenyuan Qi, Yi Qiang, Evren Asma, Jeffrey Kolthammer
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Publication number: 20210208293Abstract: A method of normalizing detector elements in an imaging system is described herein. The method includes a line source that is easier to handle for a user, and decouples the normalization of the detector elements into a transaxial domain and an axial domain in order to isolate errors due to positioning of the line source. Additional simulations are performed to augment the real scanner normalization. A simulation of a simulated line source closely matching the real line source can be performed to isolate errors due to physical properties of the crystals and position of the crystals in the system, wherein the simulated detector crystals are otherwise modeled uniformly. A simulation of a simulated cylinder source can be performed to determine errors due to other effects stemming from gaps between the detector crystals.Type: ApplicationFiled: May 5, 2020Publication date: July 8, 2021Applicant: CANON MEDICAL SYSTEMS CORPORATIONInventors: Wenyuan QI, Yi QIANG, Evren ASMA, Xiaoli LI, Li YANG, Peng PENG, Jeffrey KOLTHAMMER
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Patent number: 11049294Abstract: A method and apparatus is provided to iteratively reconstruct an image from gamma-ray emission data by optimizing an objective function with a spatially-varying regularization term. The image is reconstructed using a regularization term that varies spatially based on an activity-level map to spatially vary the regularization term in the objective function. For example, more smoothing (or less edge-preserving) can be imposed where the activity is lower. The activity-level map can be used to calculate a spatially-varying smoothing parameter and/or spatially-varying edge-preserving parameter. The smoothing parameter can be a regularization parameter ? that scales/weights the regularization term relative to a data fidelity term of the objective function, and the regularization parameter ? can depend on a sensitivity parameter. The edge-preserving parameter ? can control the shape of a potential function that is applied as a penalty in the regularization term of the objective function.Type: GrantFiled: October 2, 2018Date of Patent: June 29, 2021Assignee: CANON MEDICAL SYSTEMS CORPORATIONInventors: Li Yang, Wenyuan Qi, Chung Chan, Evren Asma
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Publication number: 20200405255Abstract: The present disclosure provides a method and apparatus for detecting a dose distribution of an article. The method includes performing a fluoroscopy scanning on the article to be detected, to obtain mass data per unit area or unit volume for each point of the article to be detected; obtaining corresponding dose distribution data based on the mass data per unit area or unit volume and a preset mapping model, wherein the preset mapping model includes a mapping relationship between mass per unit area or unit volume and the dose distribution of the article under irradiation of a preset amount of energy; and matching the dose distribution data with a fluoroscopy image of the article to be detected, to generate and display a radiation image.Type: ApplicationFiled: June 24, 2020Publication date: December 31, 2020Inventors: Zhiqiang Chen, Yuanjing Li, Zhiwei Han, Guang Yang, Huaili Qin, Wenyuan Qi, Shan Kuang, Aifeng Liang, Yanqin Liu
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Patent number: 10743830Abstract: A method and apparatus is provided to correct for scatter in a positron emission tomography (PET) scanner, the scatter coming from both within and without a field of view (FOV) for true coincidences. For a region of interest (ROI), the outside-the-FOV scatter correction are based on attenuation maps and activity distributions estimated from short PET scans of extended regions adjacent to the ROI. Further, in a PET/CT scanner, these short PET scans can be accompanied by low-dose X-ray computed tomography (CT) scans in the extended regions. The use of short PET scans, rather than full PET scans, provides sufficient accuracy for outside-the-FOV scatter corrections with the advantages of a lower radiation dose (e.g., low-dose CT) and requiring less time. In the absence of low-dose CT scans, an atlas of attenuation maps or a joint-estimation method can be used to estimate the attenuation maps for the extended regions.Type: GrantFiled: December 4, 2018Date of Patent: August 18, 2020Assignee: CANON MEDICAL SYSTEMS CORPORATIONInventors: Wenyuan Qi, Chung Chan, Li Yang, Evren Asma
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Publication number: 20200170605Abstract: A method and apparatus is provided to correct for scatter in a positron emission tomography (PET) scanner, the scatter coming from both within and without a field of view (FOV) for true coincidences. For a region of interest (ROI), the outside-the-FOV scatter correction are based on attenuation maps and activity distributions estimated from short PET scans of extended regions adjacent to the ROI. Further, in a PET/CT scanner, these short PET scans can be accompanied by low-dose X-ray computed tomography (CT) scans in the extended regions. The use of short PET scans, rather than full PET scans, provides sufficient accuracy for outside-the-FOV scatter corrections with the advantages of a lower radiation dose (e.g., low-dose CT) and requiring less time. In the absence of low-dose CT scans, an atlas of attenuation maps or a joint-estimation method can be used to estimate the attenuation maps for the extended regions.Type: ApplicationFiled: December 4, 2018Publication date: June 4, 2020Applicant: CANON MEDICAL SYSTEMS CORPORATIONInventors: Wenyuan QI, Chung Chan, Li Yang, Evren Asma
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Publication number: 20200105032Abstract: A method and apparatus is provided to iteratively reconstruct an image from gamma-ray emission data by optimizing an objective function with a spatially-varying regularization term. The image is reconstructed using regularization term that varies spatially based on an activity-level map to spatially vary the regularization term in the objective function. For example, more smoothing (or less edge-preserving) can be imposed where the activity is lower. The activity-level map can be used to calculate a spatially-varying smoothing parameter and/or spatially-varying edge-preserving parameter. The smoothing parameter can be a regularization parameter ? that scales/weights the regularization term relative to a data fidelity term of the objective function, and the regularization parameter ? can depend on a sensitivity parameter. The edge-preserving parameter ? can control the shape of a potential function that is applied as a penalty in the regularization term of the objective function.Type: ApplicationFiled: October 2, 2018Publication date: April 2, 2020Applicant: CANON MEDICAL SYSTEMS CORPORATIONInventors: Li YANG, Wenyuan QI, Chung CHAN, Evren ASMA
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Patent number: 9799126Abstract: An apparatus for performing a non-local means (NLM) filter is described. The pixel of the NLM-filtered image are weighted averages of pixels from a noisy image, where the weights are a measure of the similarity between patches of the noisy image. The similarity weights can be calculated using a Kullback-Leibler or a Euclidean distance measure. The similarity weights can be based on filtered patches of the noisy image. The similarity weights can be based on a similarity measure between patches of an anatomical image corresponding to the noisy image. The similarity weights can be calculated using a time series of noisy images to increase the statistical sample size of the patches. The similarity weights can be calculated using a weighted sum of channel similarity weights calculated between patches of noisy image that have been band-pass filtered. The NLM-filtered image can also be blended with a non-NLM-filtered image.Type: GrantFiled: October 2, 2015Date of Patent: October 24, 2017Assignee: Toshiba Medical Systems CorporationInventors: Wenyuan Qi, Xiaofeng Niu, Evren Asma, Wenli Wang, Ting Xia