Patents by Inventor Werner A. Krause

Werner A. Krause has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7635785
    Abstract: The invention relates to a process for preparation of salts of dialkylphosphinic acids, which comprises a) reacting hypophosphorous acid and/or its salts with olefins in the presence of a free-radical initiator to give dialkylphosphinic acids and/or their alkali metal salts, in a solvent system, and b) reacting the dialkylphosphinic acids and/or alkali metal dialkylphosphinates obtained in a) with compounds of the metals Mg, Ca, Al, Zn, Ti, Sn, Zr, and/or Fe to give the dialkylphosphinic salts of these metals. The invention also relates to the use of the metal dialkylphosphinic salts obtained by the inventive process, in particular for preparation of flame retardants.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: December 22, 2009
    Assignee: Clariant Deutschland GmbH
    Inventors: Harald Bauer, Werner Krause, Martin Sicken, Norbert Weferling
  • Patent number: 7622517
    Abstract: The invention relates to a phosphorus-containing flame retardant formulation for cellulose-containing moldings, comprising from 0.1 to 99.9% by weight of a resin of an organic nitrogen compound and from 0.1 to 99.9% by weight of a phosphorus-containing flame retardant.
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: November 24, 2009
    Assignee: Clariant Produkte (Deutschland) GmbH
    Inventors: Harald Bauer, Werner Krause, Martin Sicken, Volker Thewes
  • Publication number: 20090280122
    Abstract: The use of a virus regimen, especially an oncolytic regimen for the production of a medicament for the treatment of a disease, especially cancer is described. The virus regimen is applied after reducing, shutting down or modifying functioning of the immune system in a controlled manner. In a preferred embodiment T-cell depletion or T-cell modification is used for controlling the immune system. The T-cell depletor or T-cell modifier is administered either separately or as part of the virotherapy regimen.
    Type: Application
    Filed: May 8, 2009
    Publication date: November 12, 2009
    Applicant: BAYER SCHERING PHARMA AG
    Inventor: Werner KRAUSE
  • Publication number: 20090137707
    Abstract: The invention relates to mixtures of diorganylphosphinic acids and carboxylic acids of the formula [cationn+(phosphinate?)x(carboxylic acid anionz?1/z)y] where n=from 1 to 4 x=from 0.01 to n?0.01 y=n?x z=from 1 to 4, where “cation” means an element of the second main and/or transition group, an element of the third main and/or transition group, an element of the fourth main and/or transition group, an element of the fifth main and/or transition group, an element of the sixth transition group, an element of the seventh transition group, and/or an element of the eighth transition group, “phosphinate” means the anion of diorganylphosphinic acids of the formula where R1 and R2 are identical or different and, independently of one another, are H, C1-C6-alkyl, linear or branched, and/or aryl, and/or hydroxyalkyl, and “carboxylic acid anion” means C1-C18 carboxylic acid anions. The invention also relates to processes for their production, and to their use.
    Type: Application
    Filed: November 21, 2008
    Publication date: May 28, 2009
    Inventors: Harald Bauer, Werner Krause, Wolfgang Wanzke
  • Patent number: 7485745
    Abstract: The invention relates to mixtures composed of dialkylphosphinic esters and of further components, which comprise A) from 98 to 100% by weight of monocarboxy-functionalized dialkylphosphinic esters of the formula (I) in which R1, R2, R3, R4, R5, R6, and R7 are identical or different and, independently of one another, are H, methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, tert-butyl, and/or phenyl, Y is methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, tert-butyl, phenyl, 2-hydroxyethyl, 2,3-dihydroxypropyl, 2-hydroxypropyl, 3-hydroxypropyl, 4-hydroxybutyl, 3-hydroxybutyl, 2-hydroxybutyl, and/or 6-hydroxyhexyl, allyl, and/or glycerol, X is H, Li, Na, K or NH4, or X is defined as for Y, and then X and Y are two identical radicals or two different radicals of the above organic radicals, and B) from 0 to 2% by weight of halogens, where the entirety of the components always amounts to 100% by weight.
    Type: Grant
    Filed: March 6, 2007
    Date of Patent: February 3, 2009
    Assignee: Clariant International Ltd.
    Inventors: Wiebke Maas, Werner Krause, Harald Bauer
  • Patent number: 7482398
    Abstract: The invention relates to an elastic covering material, which comprises, as a flame retardant, a phosphinate salt of the formula (I) and/or a diphosphinate salt of the formula (II) and/or polymers thereof where R1, R2 are the same or different and are each C1-C6-alkyl, linear or branched, and/or aryl; R3 is C1-C10-alkylene, linear or branched, C6-C10-arylene, -alkylarylene or -arylalkylene; M is Mg, Ca, Al, Sb, Sn, Ge, Ti, Zn, Fe, Zr, Ce, Bi, Sr, Mn, Li, Na, K and/or a protonated nitrogen base; m is from 1 to 4; n is from 1 to 4; x is from 1 to 4. The invention relates to processes for producing such elastic covering materials.
    Type: Grant
    Filed: July 13, 2004
    Date of Patent: January 27, 2009
    Assignee: Clariant Produkte (Deutschland) GmbH
    Inventors: Harald Bauer, Hans-Matthias Deger, Werner Krause
  • Publication number: 20090005471
    Abstract: The invention relates to a phosphorus-containing flame retardant formulation for cellulose-containing moldings, comprising from 0.1 to 99.9% by weight of a resin of an organic nitrogen compound and from 0.1 to 99.9% by weight of a phosphorus-containing flame retardant.
    Type: Application
    Filed: April 18, 2008
    Publication date: January 1, 2009
    Inventors: Harald Bauer, Werner Krause, Martin Sicken, Volker Thewes
  • Patent number: 7446140
    Abstract: The invention relates to diorganylphosphinic salts of the formula (I) and/or diorganyldiphosphinic salts of the formula (II) and/or any of their polymers where R1 and R2 are identical or different and are C1-C6-alkyl, linear or branched, and/or aryl; R3 is C1-C10-alkylene, linear or branched, C6-C10-arylene, -alkylarylene, or -arylalkylene; M is Mg, Ca, Al, Sb, Sn, Ge, Ti, Fe, Zr, Zn, Ce, Bi, Sr, Mn, Li, Na, K, and/or a protonated nitrogen base; m is from 1 to 4; n is from 1 to 4; x is from 1 to 4, wherein the total content of partially water-soluble, ionizable compounds and the water-soluble content of the partially water-soluble, ionizable compounds is from 8200 to 100 ppm, preferably from 7000 to 200 ppm.
    Type: Grant
    Filed: May 11, 2005
    Date of Patent: November 4, 2008
    Assignee: Clariant Produkte (Deutschland) GmbH
    Inventors: Harald Bauer, Werner Krause, Martin Sicken, Norbert Weferling
  • Publication number: 20080241529
    Abstract: The invention relates to flameproofed adhesive and sealing materials containing 0.1-99.9% by weight of adhesive or thermoplastic polymer and 0.1-99.9% by weight of flameproofing agent, wherein the flameproofing agent contains at least one phosphinic acid salt of the formula (I) and/or one diphosphinic acid salt of the formula (II) in which R1, R2 are identical or different and are C1-C6-alkyl, linear or branched, and/or aryl; R3 is C1-C10-alkylene, linear or branched, C6-C10-arylene, C6-C10-alkylarylene or C6-C10-arylalkylene; M is Mg, Ca, Al, Zn, Sb, Sn, Ge, Zn, Ti, Fe, Zr, Ce, Bi, Sr, Mn, Li, Na, K and/or a protonated nitrogen base; m is 1 to 4; n is 1 to 4 and x is 1 to 4, the adhesive polymers being acrylate resins, polyurethane resins, saturated and unsaturated polyester resins, styrene-butadiene copolymers, vinyl acetate copolymers, silicones, synthetic rubber and/or polyolefin resins.
    Type: Application
    Filed: March 25, 2008
    Publication date: October 2, 2008
    Inventors: Harald Bauer, Mathias Dietz, Werner Krause
  • Publication number: 20080233128
    Abstract: A method of treating viral infections comprises administering to a patient a regimen that is able to temporarily reduce the number or functionality of the host cells which the virus uses for its reproduction in a controlled manner. Preferably, host cells are part of the immune system.
    Type: Application
    Filed: November 1, 2007
    Publication date: September 25, 2008
    Inventor: Werner Krause
  • Publication number: 20080214708
    Abstract: The invention relates to asymmetrically substituted phosphinic acids of the formula (I) R1R2C(OH)—P(?O)(OX)—C(OH)R3R4 ??(I) in which X is hydrogen R1, R2, R3, and R4 are identical or different and are hydrogen, alkyl, alkenyl, alkynyl, aralkyl, aryl and/or alkaryl, with the proviso that the respective R1R2C(OH)— and —C(OH)R3R4 groups are always different, to a process for their preparation, and to their use.
    Type: Application
    Filed: September 28, 2007
    Publication date: September 4, 2008
    Inventors: Harald Bauer, Michael Hill, Werner Krause
  • Patent number: 7420007
    Abstract: The invention relates to dialkylphosphinic salts of the formula (I) where R1, R2 identical or different, are C1-C6-alkyl, linear or branched M is Mg, Ca, Al, Sb, Sn, Ge, Ti, Fe, Zr, Zn, Ce, Bi, Sr, Mn, Li, Na, K and/or is a protonated nitrogen base; m is from 1 to 4; wherein the telomer content is from 0.01 to 6% by weight. The invention also relates to glare use in flame retardant compositions, and to flame-retardant polymer molding compositions and flame-retardant polymer moldings which comprise these dialkylphosphinic salts.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: September 2, 2008
    Assignee: Clariant Produkte (Deutschland) GmbH
    Inventors: Harald Bauer, Werner Krause, Martin Sicken, Norbert Weferling
  • Publication number: 20080188598
    Abstract: The invention relates to salts of alkyl esters of carboxyethyl(alkyl)phosphinic acid, where the salts have the formula (I) R1—P(?O)(OX)—CH2—CH2—CO2R2 in which R1 and R2 are identical or different and, independently of one another, are C1-C20-alkyl, C2-C20-alkenyl, C1-C20-alkynyl, and/or C6-C20-aralkyl, and X is an alkali metal, an element of the second main and transition group, an element of the third main and transition group, an element of the fourth main and transition group, an element of the fifth main and transition group, an element of the sixth main group, an element of the seventh transition group, or an element of the eighth transition group, and also to processes for their preparation, and to their use.
    Type: Application
    Filed: December 7, 2007
    Publication date: August 7, 2008
    Inventors: Harald Bauer, Sebastian Hoerold, Werner Krause
  • Publication number: 20080171800
    Abstract: The invention relates to a flame-retardant resin formulation comprising respectively at least one flame-retardant component, one alkali-soluble component, one polymerizable monomer, one photoinitiator, and one epoxy component, which comprises, as flame-retardant component, a phosphinic salt of the formula (I), in which R1 and R2 are identical or different and, independently of one another, are C1-C6-alkyl, linear or branched, and/or aryl; M is Mg, Ca, Al, Sb, Sn, Ge, Ti, Zn, Fe, Zr, Ce, Bi, Sr, Mn, Li, Na, K, and/or a protonated nitrogen base, and m is from 1 to 4. This novel flame-retardant resin formulation is preferably used as solder resist.
    Type: Application
    Filed: January 11, 2008
    Publication date: July 17, 2008
    Inventors: Mathias Dietz, Harald Bauer, Werner Krause
  • Publication number: 20080146708
    Abstract: The invention relates to salts of asymmetrically substituted bis(1-hydroxymethyl)phosphinic acids, of the formula (I) A-P(?O)(OX)—B ??(I) in which A is R1R2C(OH)— and B is R3R4C(OH)—, with the proviso that the respective groups R1R2C(OH)— and —C(OH)R3R4 are always different, and where R1, R2, R3, and R4 are hydrogen, alkyl, alkenyl, alkynyl, aralkyl, aryl and/or substituted aryl, and X is an element of the first main group, an element of the second main or transition group, an element of the third main or transition group, an element of the fourth main or transition group, an element of the eighth transition group and/or a nitrogen base.
    Type: Application
    Filed: December 14, 2007
    Publication date: June 19, 2008
    Inventors: Harald Bauer, Werner Krause, Wiebke Maas
  • Patent number: 7348396
    Abstract: The invention relates to polymeric phosphinic acids and their salts of the formula (I) where X is hydrogen or 1/m of a metal of valency m, or is a protonated nitrogen base, R1 and R2 are identical or different and are hydrogen, a carboxy group, a carboxylic acid derivative, an unsubstituted or substituted alkyl group having from 1 to 10 carbon atoms, phenyl, benzyl, or alkyl-substituted aromatic systems, R3 and R4 may be identical or different and are an unsubstituted or substituted alkyl group having from 2 to 20 carbon atoms, or are OX, with the above meaning for X, and ? is the average number of monomer units. The invention further relates to a process for preparing the abovementioned compounds, and to their use.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: March 25, 2008
    Assignee: Clariant Produkte (Deutschland) GmbH
    Inventors: Martin Sicken, Werner Krause, Norbert Weferling, Hans-Peter Schmitz
  • Publication number: 20070213563
    Abstract: The invention relates to mixtures composed of monocarboxy-functionalized dialkylphosphinic salts and of further components, which comprise A) from 98 to 100% by weight of monocarboxy-functionalized dialkylphosphinic salts of the formula (I) in which X and Y are different, where X is Ca, Al, or Zn, and Y is methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, tert-butyl, phenyl, 2-hydroxyethyl, 2,3-dihydroxypropyl, 2-hydroxypropyl, 3-hydroxypropyl, 4-hydroxybutyl, 3-hydroxybutyl, 2-hydroxybutyl, and/or 6-hydroxyhexyl, allyl and/or glycerol; or X and Y are different and are Mg, Sb, Sn, Ge, Ti, Fe, Zr, Ce, Bi, Sr, Mn, Cu, Ni, Li, Na, K, H, and/or a protonated nitrogen base; or X and Y are identical or different and each is then Ca, Al, or Zn; R1, R2, R3, R4, R5, R6, and R7 are identical or different and, independently of one another, are H, methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, tert-butyl, and/or phenyl, and B) from 0 to 2% by weight of halogens, where the entirety of the components a
    Type: Application
    Filed: March 6, 2007
    Publication date: September 13, 2007
    Inventors: Wiebke Maas, Werner Krause, Harald Bauer
  • Publication number: 20070210288
    Abstract: The invention relates to mixtures composed of dialkylphosphinic esters and of further components, which comprise A) from 98 to 100% by weight of monocarboxy-functionalized dialkylphosphinic esters of the formula (I) in which R1, R2, R3, R4, R5, R6, and R7 are identical or different and, independently of one another, are H, methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, tert-butyl, and/or phenyl, Y is methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, tert-butyl, phenyl, 2-hydroxyethyl, 2,3-dihydroxypropyl, 2-hydroxypropyl, 3-hydroxypropyl, 4-hydroxybutyl, 3-hydroxybutyl, 2-hydroxybutyl, and/or 6-hydroxyhexyl, allyl, and/or glycerol, X is H, Li, Na, K or NH4, or X is defined as for Y, and then X and Y are two identical radicals or two different radicals of the above organic radicals, and B) from 0 to 2% by weight of halogens, where the entirety of the components always amounts to 100% by weight.
    Type: Application
    Filed: March 6, 2007
    Publication date: September 13, 2007
    Inventors: Wiebke Maas, Werner Krause, Harald Bauer
  • Publication number: 20070213436
    Abstract: The invention relates to mixtures composed of monocarboxy-functionalized dialkylphosphinic acids and of further components, which comprise A) from 98 to 100% by weight of monocarboxy-functionalized dialkylphosphinic acids of the formula (I) in which R1, R2, R3, R4, R5, R6, and R7 are identical or different and, independently of one another, are H, methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, tert-butyl, and/or phenyl, X and Y are identical or different and, independently of one another, are H, Li, Na, K, or NH4, and B) from 0 to 2% by weight of halogens, where the entirety of the components always amounts to 100% by weight.
    Type: Application
    Filed: March 6, 2007
    Publication date: September 13, 2007
    Inventors: Wiebke Maas, Werner Krause, Harald Bauer
  • Patent number: 7259200
    Abstract: The invention relates to phosphorus-containing flame retardant agglomerates comprising a) from 99.99 to 80% by weight of aggregates and/or primary particles composed of a phosphinic salt of the formula (I) and/or composed of a diphosphinic salt of the formula (II), and/or composed of polymers of these, where R1,R2 are identical or different and are C1-C6-alkyl, linear or branched, and/or aryl; R3 is C1-C10-alkylene, linear or branched, C6-C10-arylene, -alkylarylene or -arylalkylene; M is Mg, Ca, Al, Sb, Sn, Ge, Ti, Fe, Zr, Ce, Bi, Sr, Mn, Li, Na, K and/or a protonated nitrogen base; m is from 1 to 4; n is from 1 to 4; x is from 1 to 4 and b) from 0.01 to 20% by weight of auxiliaries. The invention likewise relates to a process for the production of these phosphorus-containing flame retardant agglomerates, and also to polymeric compositions and moldings which comprise these phosphorus-containing flame retardant agglomerates.
    Type: Grant
    Filed: October 6, 2004
    Date of Patent: August 21, 2007
    Assignee: Clariant Produkte (Deutschland) GmbH
    Inventors: Harald Bauer, Sebastian Hoerold, Werner Krause, Martin Sicken