Abstract: Techniques are disclosed relating to providing a web application capable of executing within a particular web browser or a client application native to a client platform. The particular web browser and the client platform support differing sets of features. A server computer system hosts the web application for distributing to instances of the client application. The server computer system receives, from a particular instance of the client application that is executing on a client device that implements the client platform, a request for the web application. The server computer system sends the web application to the particular instance to cause the web application to be executed within the particular instance. Such execution of the web application permits the web application to use at least one feature not supported by the particular web browser.

Abstract: Technologies are provided for synchronizing and joining multiple calls from a first thread and one or more second threads to execute a particular code segment. In response to a call from the first thread to execute the particular code segment, a task synchronizer module calls the particular code segment on behalf of the first thread. When execution of the particular code segment starts, and a call is received from a second thread to execute the particular code segment after receiving the call from the first thread, the task synchronizer module suspends execution of the particular code segment so that the second thread awaits for the execution of the particular code segment on behalf of the first thread to complete. When execution completes, a result value or exception is stored in a task object, and the second thread can read the result value or the exception.

Abstract: A method for managing oilfield water. Oilfield water data is grouped into discrete and non-overlapping groups. Outliers are removed from the data. Features of the remaining data are analyzed to identify most discriminative feature. The data is separated into training data and testing data, and the training data is fit into a model that shows the best precision, accuracy and recall. The model is confirmed using the testing data. Upon confirmation of the accuracy of the model, the model is applied to data for a new proposed oilfield well, and a new proposed project is implemented or disapproved based on a result of the identified model that predicts water production of the new proposed oilfield well.

Abstract: A method for managing oilfield water. Oilfield water data is grouped into discrete and non-overlapping groups. Outliers are removed from the data. Features of the remaining data are analyzed to identify most discriminative feature. The data is separated into training data and testing data, and the training data is fit into a model that shows the best precision, accuracy and recall. The model is confirmed using the testing data. Upon confirmation of the accuracy of the model, the model is applied to data for a new proposed oilfield well, and a new proposed project is implemented or disapproved based on a result of the identified model that predicts water production of the new proposed oilfield well.

Abstract: The invention relates to FSH receptor antagonist according to general formula I or a pharmaceutically acceptable salt thereof and to a pharmaceutical composition containing the same. The compounds can be used for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, and for the treatment of uterine fibroids and other menstrual-related disorders.

Abstract: Systems and methods for updating a scale of a barometric altimeter on aircraft are provided. The method, for example, may include, but is not limited to, receiving, by an aircraft communication system, barometric altimeter scale data corresponding to an atmospheric pressure at an airport, determining, by the processor, if the altitude of the aircraft is below a transition level for the airport, and adjusting, by the processor, the scale of the barometric altimeter based upon the received barometric altimeter scale data when the altitude of the aircraft is below the transition level for the airport.

Abstract: A method for managing oilfield water. Oilfield water data is grouped into discrete and non-overlapping groups. Outliers are removed from the data. Features of the remaining data are analyzed to identify most discriminative feature. The data is separated into training data and testing data, and the training data is fit into a model that shows the best precision, accuracy and recall. The model is confirmed using the testing data. Upon confirmation of the accuracy of the model, the model is applied to data for a new proposed oilfield well, and a new proposed project is implemented or disapproved based on a result of the identified model that predicts water production of the new proposed oilfield well.

Abstract: The invention relates to FSH receptor antagonist according to general formula I or a pharmaceutically acceptable salt thereof and to a pharmaceutical composition containing the same. The compounds can be used for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, and for the treatment of uterine fibroids and other menstrual-related disorders.

Abstract: The invention relates to FSH receptor antagonist according to general formula (I) or a pharmaceutically acceptable salt thereof and to a pharmaceutical composition containing the same. The compounds can be used for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, and for the treatment of uterine fibroids and other menstrual-related disorders.

Abstract: The invention relates to FSH receptor antagonist according to general formula I or a pharmaceutically acceptable salt thereof and to a pharmaceutical composition containing the same. The compounds can be used for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, and for the treatment of uterine fibroids and other menstrual-related disorders.

Abstract: The invention relates to a N-piperidin-4-yl derivative having the general Formula I or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same and to the use of said N-piperidin-4-yl derivatives for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, or for the treatment of uterine fibroids or other menstrual-related disorders.

Abstract: The invention relates to FSH receptor antagonist according to general formula (I) or a pharmaceutically acceptable salt thereof and to a pharmaceutical composition containing the same. The compounds can be used for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, and for the treatment of uterine fibroids and other menstrual-related disorders.

Abstract: The invention relates to a N-piperidin-4-yl derivative having the general Formula I or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same and to the use of said N-piperidin-4-yl derivatives for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, or for the treatment of uterine fibroids or other menstrual-related disorders.

Abstract: The invention relates to FSH receptor antagonist according to general formula I or a pharmaceutically acceptable salt thereof and to a pharmaceutical composition containing the same. The compounds can be used for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, and for the treatment of uterine fibroids and other menstrual-related disorders.

Abstract: Methods and apparatus are provided for automated control of aerodrome lighting. An exemplary system includes a communication radio, an aerodrome lighting data source, and a processor. The communication radio is configured to selectively transmit radio frequency (RF) signals. The aerodrome lighting data source is configured to at least selectively supply aerodrome lighting data representative of light control characteristics of aerodrome lighting associated with individual aerodromes. The processor is in operable communication with the aerodrome lighting data source and the communication radio, and is configured to selectively retrieve, from the aerodrome lighting data source, aerodrome lighting data associated with an individual aerodrome, and selectively command the communication radio to transmit RF signals consistent with the light control characteristics associated with the individual aerodrome.

Abstract: Systems and methods for updating a scale of a barometric altimeter on aircraft are provided. The method, for example, may include, but is not limited to, receiving, by an aircraft communication system, barometric altimeter scale data corresponding to an atmospheric pressure at an airport, determining, by the processor, if the altitude of the aircraft is below a transition level for the airport, and adjusting, by the processor, the scale of the barometric altimeter based upon the received barometric altimeter scale data when the altitude of the aircraft is below the transition level for the airport.

Abstract: Methods and apparatus are provided for automated control of aerodrome lighting. An exemplary system includes a communication radio, an aerodrome lighting data source, and a processor. The communication radio is configured to selectively transmit radio frequency (RF) signals. The aerodrome lighting data source is configured to at least selectively supply aerodrome lighting data representative of light control characteristics of aerodrome lighting associated with individual aerodromes. The processor is in operable communication with the aerodrome lighting data source and the communication radio, and is configured to selectively retrieve, from the aerodrome lighting data source, aerodrome lighting data associated with an individual aerodrome, and selectively command the communication radio to transmit RF signals consistent with the light control characteristics associated with the individual aerodrome.

Abstract: A compound of the formula (I): wherein R1, R2, R3, R4, Ar, A, n and m are defined herein, is disclosed as a GlyT1 inhibitor; pharmaceutical compositions containing the compound of the formula (I) are also disclosed as are their use in medicine, for example in the treatment of schizophrenia.

Abstract: The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain pyridine benzamide and pyrazine benzamide compounds (referred to herein as PDBA and PZBA compounds) which, inter alia, inhibit protein kinase D (PKD) (e.g., PKD1, PKD2, PKD3). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit PKD, and in the treatment of diseases and conditions that are mediated by PKD, that are ameliorated by the inhibition of PKD, etc., including proliferative conditions such as cancer, etc.

Abstract: The present invention provides compounds of formula I: wherein R1 is an alkyl, phenyl, heterocyclyl, cycloalkyl, alkoxy, ester, amino or amide group; R2 is a phenyl, heterocyclyl, alkyl, cycloalkyl or cycloalkylalkyl group; R3 is an alkyl, cycloalkyl, cycloalkylalkyl, amino or heterocyclyl group; R4 and R5 are hydrogen or alkyl or form a cycloalkyl ring; A is O or N; and m is zero or one; as inhibitors of GlyT1 and thus as useful for treating or preventing diseases such as schizophrenia; with the provision of pharmaceutical compositions, first and second medical uses and methods of treatment.