Patents by Inventor Wha Bin Im

Wha Bin Im has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phenyl bicyclic methyl amine derivatives as sphingosine-1 phosphate receptors modulators
    Patent number: 8541582
    Abstract: The present invention relates to novel phenyl bicyclic methyl amine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: September 24, 2013
    Assignee: Allergan, Inc.
    Inventors: Janet A. Takeuchi, Ling Li, Wha Bin Im
  • COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS
    Publication number: 20130243740
    Abstract: The present specification discloses compositions and methods of transplanting tissue, for example, in breast augmentation procedures. The compositions include adipose tissue and compounds that reduce tissue volume loss and increase survival rate of the adipose tissue when the composition is introduced into breast tissue.
    Type: Application
    Filed: May 3, 2013
    Publication date: September 19, 2013
    Applicant: Allergan, Inc.
    Inventors: Dennis Van Epps, Guang-Liang Jiang, Wha Bin Im
  • THERAPEUTIC AND DELIVERY METHODS OF PROSTAGLANDIN EP4 AGONISTS
    Publication number: 20130245283
    Abstract: A compound comprising a prodrug of a prostaglandin EP4 agonist, wherein said prodrug is an ester, ether, or amide of an amino acid is disclosed herein. Maintenance of the colonic mucosal barrier by method comprising administering a therapeutically effective amount of a prostaglandin EP4 agonist to a colon of a mammal is also disclosed herein. Dosage forms, medicaments, and compositions, related thereto are also disclosed.
    Type: Application
    Filed: April 23, 2013
    Publication date: September 19, 2013
    Applicant: Allergan, Inc.
    Inventors: Wha-Bin Im, Robert M. Burk, Mark Holoboski
  • Indole modulators of S1P receptors
    Patent number: 8530462
    Abstract: The present invention relates to novel indole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: November 10, 2011
    Date of Patent: September 10, 2013
    Assignee: Allergan, Inc.
    Inventors: Santosh C. Sinha, Smita S. Bhat, Ken Chow, Michael E. Garst, Wha Bin Im
  • Oxime azetidine derivatives as sphingosine 1-phosphate (S1P) receptor modulators
    Patent number: 8518932
    Abstract: The present invention relates to novel oxime azetidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: November 21, 2011
    Date of Patent: August 27, 2013
    Assignee: Allergan, Inc.
    Inventors: Wenkui K. Fang, Liming Wang, Evelyn G. Corpuz, Ken Chow, Wha-Bin Im
  • Compositions and methods for soft tissue replacement
    Patent number: 8518396
    Abstract: The present invention is directed to compositions and methods of transplanting tissue, for example, in breast augmentation procedures. The compositions include adipose tissue and compounds that reduce tissue volume loss and increase survival rate of the adipose tissue when the composition is introduced into breast tissue.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: August 27, 2013
    Assignee: Allergan, Inc.
    Inventors: Dennis E. Van Epps, Guang-Liang Jiang, Wha Bin Im
  • Substituted bicyclic methyl amine derivatives as sphingosine-1 phosphate receptors modulators
    Patent number: 8513418
    Abstract: The present invention relates to novel substituted bicyclic methyl amine derivatives which are useful as sphingosine-1-phosphate receptors modulators and useful for treating a wide variety of disorders associated with modulation of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: August 20, 2013
    Assignee: Allergan, Inc.
    Inventors: Janet A. Takeuchi, Ling Li, Wha Bin Im
  • Phenyl bicyclic methyl azetidine derivatives as sphingosine-1 phosphate receptors modulators
    Patent number: 8507685
    Abstract: The present invention relates to novel phenyl bicyclic methyl azetidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: August 13, 2013
    Assignee: Allergan, Inc.
    Inventors: Janet A. Takeuchi, Ling Li, Wha Bin Im
  • Substituted bicyclic methyl azetidines as sphingosine-1 phosphate receptors modulators
    Patent number: 8507686
    Abstract: The present invention relates to novel substituted bicyclic methyl azetidine derivatives which are useful as sphingosine-1-phosphate receptors modulators and useful for treating a wide variety of disorders associated with modulation of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: April 9, 2012
    Date of Patent: August 13, 2013
    Assignee: Allergan, Inc.
    Inventors: Janet A. Takeuchi, Ling Li, Wha Bin Im
  • Condensed ring pyridine compounds as subtype-selective modulators of sphingosine-1-phosphate-2 (S1P) receptors
    Patent number: 8507682
    Abstract: The invention provides compounds represented by the formula I, each of which compounds may have sphingosine-1-phosphate receptor agonist and or antagonist biological activity, wherein these compounds selected from the group consisting of wherein A, B, C, D, X, Y, Z and R3 are defined in the specification. Said compounds are useful for treating a disease or condition of a mammal selected from the group consisting of ocular diseases; systemic vascular barrier related diseases; allergies and other inflammatory diseases; cardiac diseases or conditions; fibrosis; pain and wounds.
    Type: Grant
    Filed: September 28, 2010
    Date of Patent: August 13, 2013
    Assignee: Allergan, Inc.
    Inventors: Wenkiu K. Fang, Liming Wang, Evelyn G. Corpuz, Ken Chow, Wha-Bin Im
  • Azetidine derivatives as sphingosine 1-phosphate (S1P) receptor modulators
    Patent number: 8501726
    Abstract: The present invention relates to novel azetidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: November 10, 2011
    Date of Patent: August 6, 2013
    Assignee: Allergan, Inc.
    Inventors: Wenkui K. Fang, Liming Wang, Evelyn G. Corpuz, Ken Chow, Wha Bin Im
  • Phosphonic acids as S1P receptor modulators
    Patent number: 8497255
    Abstract: The present invention relates to novel phosphonic acids derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: November 16, 2011
    Date of Patent: July 30, 2013
    Assignee: Allergan, Inc.
    Inventors: Janet A. Takeuchi, Ling Li, Ken Chow, Wha-Bin Im
  • Oxadiazole derivatives as sphingosine 1-phosphate (S1P) receptor modulators
    Patent number: 8497254
    Abstract: The present invention relates to novel oxadiazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: July 30, 2013
    Assignee: Allergan, Inc.
    Inventors: Wenkui K. Fang, Liming Wang, Evelyn G. Corpuz, Ken Chow, Wha Bin Im
  • Azetidine derivatives as sphingosine 1-phosphate (S1P) receptor modulators
    Patent number: 8492561
    Abstract: The present invention relates to novel azetidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: July 23, 2013
    Assignee: Allergan, Inc.
    Inventors: Santosh C. Sinha, Smita S. Bhat, Evelyn G. Corpuz, Ken Chow, Wenkui K. Fang, Wha-Bin Im
  • Pyridine derivatives as sphingosine 1-phosphate (S1P) receptor modulators
    Patent number: 8492410
    Abstract: The present invention relates to novel pyridine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: July 23, 2013
    Assignee: Allergan, Inc.
    Inventors: Wenkui K. Fang, Liming Wang, Evelyn G. Corpuz, Ken Chow, Wha-Bin Im
  • Phenyl oxadiazole derivatives as sphingosine 1-phosphate (S1P) receptor
    Patent number: 8486918
    Abstract: The present invention relates to novel phenyl oxadiazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: July 16, 2013
    Assignee: Allergan, Inc.
    Inventors: Wenkui K. Fang, Liming Wang, Evelyn G. Corpuz, Ken Chow, Wha Bin Im
  • Alkyne and alkene derivatives as sphingosine 1-phosphate-1 receptor modulators
    Patent number: 8404663
    Abstract: The present invention relates to novel alkyne and alkene derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: March 26, 2013
    Assignee: Allergan, Inc.
    Inventors: Santosh C. Sinha, Smita S. Bhat, Evelyn G. Corpuz, Ken Chow, Wenkui K. Fang, Wha-Bin Im
  • Pyridine derivatives as sphingosine 1-phosphate (S1P) receptor modulators
    Patent number: 8399492
    Abstract: The present invention relates to novel pyridine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: March 19, 2013
    Assignee: Allergan, Inc.
    Inventors: Wenkui K. Fang, Liming Wang, Evelyn G. Corpuz, Ken Chow, Wha Bin Im
  • Therapeutic substituted lactams
    Patent number: 8362054
    Abstract: Therapeutic compounds, compositions, methods, and medicaments related thereto are disclosed herein.
    Type: Grant
    Filed: February 8, 2008
    Date of Patent: January 29, 2013
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Wha Bin Im, Vinh X. Ngo
  • COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS
    Publication number: 20120269777
    Abstract: The specification discloses compositions and methods for treating a soft tissue defect of an individual.
    Type: Application
    Filed: February 16, 2012
    Publication date: October 25, 2012
    Applicant: ALLERGAN, INC.
    Inventors: Dennis E. Van Epps, Guang-Liang Jiang, Adam L. Collette, Rebecca L. Horan, Jingsong Chen, Gregory H. Altman, Wha Bin Im