Patents by Inventor Wha Bin Im

Wha Bin Im has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reduced central corneal thickening by use of hydrophilic ester prodrugs of beta-chlorocyclopentanes
    Patent number: 9024042
    Abstract: Compositions and methods for treating glaucoma are provided. In particular hydrophilic ester prodrugs and their use to reduce central corneal thickening is provided.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: May 5, 2015
    Assignee: Allergan, Inc.
    Inventors: Wha-Bin Im, Robert M. Burk
  • Compositions and soft tissue replacement methods
    Patent number: 9005605
    Abstract: The specification discloses compositions and methods for treating a soft tissue defect of an individual.
    Type: Grant
    Filed: February 16, 2012
    Date of Patent: April 14, 2015
    Assignee: Allergan, Inc.
    Inventors: Dennis E. Van Epps, Guang-Liang Jiang, Wha Bin Im
  • 1,3,4-Oxadiazoles-2-thio derivatives as sphingosine-1 phosphate receptors modulators
    Patent number: 9000016
    Abstract: The present invention relates to substituted 1,3,4-oxadiazoles-2-thio derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: November 4, 2013
    Date of Patent: April 7, 2015
    Assignee: Allergan, Inc.
    Inventors: Janet A. Takeuchi, Ling Li, Wha-Bin Im, Ken Chow
  • Azetidine derivatives as sphingosine 1-phosphate (S1P) receptor modulators
    Patent number: 8993553
    Abstract: The present invention relates to novel azetidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: June 24, 2013
    Date of Patent: March 31, 2015
    Assignee: Allergan, Inc.
    Inventors: Santosh C. Sinha, Smita S. Bhat, Evelyn G. Corpuz, Ken Chow, Wha-Bin Im, Wenkui K. Fang
  • Substituted pyrazole azetidines as sphingosine receptor modulators
    Patent number: 8987467
    Abstract: The present invention relates to substituted pyrazole azetidines, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: February 13, 2014
    Date of Patent: March 24, 2015
    Assignee: Allergan, Inc.
    Inventors: Janet A. Takeuchi, Ling Li, Wha Bin Im, Ken Chow
  • Substituted dihydropyrazoles as sphingosine receptor modulators
    Patent number: 8987471
    Abstract: The present invention relates to substituted dihydropyrazoles, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: February 13, 2014
    Date of Patent: March 24, 2015
    Assignee: Allergan, Inc.
    Inventors: Janet A. Takeuchi, Ling Li, Wha Bin Im, Ken Chow
  • Bicyclic 1, 2, 4-oxadiazoles derivatives as sphingosine-1 phosphate receptors modulators
    Patent number: 8957051
    Abstract: The present invention relates to bicyclic aryl 1,2,4-oxadiazoles derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: February 17, 2015
    Assignee: Allergan, Inc.
    Inventors: Janet A. Takeuchi, Ling Li, Wha-Bin Im, Ken Chow
  • Bicyclic methyl amine derivatives as sphingosine-1 phosphate receptors modulators
    Patent number: 8946195
    Abstract: The present invention relates to novel bicyclic methyl amine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: March 20, 2014
    Date of Patent: February 3, 2015
    Assignee: Allergan, Inc.
    Inventors: Janet A. Takeuchi, Ling Li, Wha Bin Im
  • TREATMENT OF INFLAMMATORY BOWEL DISEASE
    Publication number: 20150018400
    Abstract: Disclosed herein is a method comprising administering a compound to a mammal suffering from an inflammatory bowel disease for the treatment of said disease, said compound having a structure according to Formula I wherein X, Y, B, R2, R3, R4, R5, R6 and n have the meanings found herein.
    Type: Application
    Filed: May 2, 2014
    Publication date: January 15, 2015
    Inventors: YARIV DONDE, JEREMIAH H. NGUYEN, KAREN M. KEDZIE, DANIEL W. GIL, JOHN E. DONELLO, WHA-BIN IM
  • Compositions and soft tissue replacement methods
    Patent number: 8926963
    Abstract: The specification discloses compositions and methods for treating a soft tissue defect of an individual.
    Type: Grant
    Filed: February 16, 2012
    Date of Patent: January 6, 2015
    Assignee: Allergan, Inc.
    Inventors: Dennis E. Van Epps, Guang-Liang Jiang, Adam L. Collette, Rebecca L. Horan, Jingsong Chen, Gregory H. Altman, Wha Bin Im
  • 2-THIO-1,3,4-OXADIAZOLES AZETIDINE DERIVATIVES AS SPHINGOSINE-1 PHOSPHATE RECEPTORS MODULATORS
    Publication number: 20140363457
    Abstract: The present invention relates to 2-thio-1,3,4-oxadiazoles azetidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Application
    Filed: August 26, 2014
    Publication date: December 11, 2014
    Inventors: Janet A. Takeuchi, Ling Li, Wha Bin Im, Ken Chow
  • Azetidine derivatives as sphingosine 1-phosphate (S1P) receptor modulators
    Patent number: 8906899
    Abstract: The present invention relates to novel azetidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: December 9, 2014
    Assignee: Allergan, Inc.
    Inventors: Wenkui K. Fang, Evelyn G. Corpuz, Wha-Bin Im, Ken Chow, Liming Wang
  • Compositions and soft tissue replacement methods
    Patent number: 8900571
    Abstract: The invention relates to compositions comprising a silk fibroin material, adipose tissue and a compound of the structure where X1 and X5 are independently CH or N; X7 is NH, O or S; X8 and X9 are independently CH or N; R13 is an optionally substituted aryl or optionally substituted heteroaryl and R14 is C1-6 alkyl, optionally substituted aryl or optionally substituted heteroaryl. The composition is administered to a site of a soft tissue condition including those of breast tissue. The silk fibroin material can be in the form of a silk hydrogel, a silk film, a silk scaffold, a silk sheet, a silk porous material or a silk fiber. The silk fibroin material can be substantially sericin free.
    Type: Grant
    Filed: February 16, 2012
    Date of Patent: December 2, 2014
    Assignee: Allergan, Inc.
    Inventors: Dennis E. Van Epps, Guang-Liang Jiang, Adam L. Collette, Rebecca L. Horan, Jingsong Chen, Gregory H. Altman, Wha Bin Im
  • Compositions and soft tissue replacement methods
    Patent number: 8894992
    Abstract: The invention relates to compositions comprising adipose tissue, a silk fibroin material and a compound of the structure The composition is administered to a site of a soft tissue condition including those of breast tissue. The silk fibroin material can be in the form of a silk hydrogel, a silk film, a silk scaffold, a silk sheet, a silk porous material, a silk fiber or a combination of those materials. The silk material may be substantially sericin free.
    Type: Grant
    Filed: February 16, 2012
    Date of Patent: November 25, 2014
    Assignee: Allergan, Inc.
    Inventors: Dennis E. Van Epps, Guang-Liang Jiang, Adam L. Collette, Rebecca L. Horan, Jingsong Chen, Gregory H. Altman, Wha Bin Im
  • Compositions and soft tissue replacement methods
    Patent number: 8889123
    Abstract: The invention relates to compositions comprising a hydrogel material that comprises a glycosaminoglycan polymer, adipose tissue and a compound of the structure where X1 and X5 are independently CH or N; X7 is NH, O or S; X8 and X9 are independently CH or N; R13 is an optionally substituted aryl or optionally substituted heteroaryl and R14 is C1-6 alkyl, optionally substituted aryl or optionally substituted heteroaryl. The composition is administered to a site of a soft tissue condition including those of breast tissue. The hydrogel material can be porous or of solid particles. The glycosaminoglycan polymer can be a hyaluronan polymer.
    Type: Grant
    Filed: February 16, 2012
    Date of Patent: November 18, 2014
    Assignee: Allergan, Inc.
    Inventors: Dennis E. Van Epps, Guang-Liang Jiang, Wha Bin Im
  • Compositions and soft tissue replacement methods
    Patent number: 8883139
    Abstract: The invention relates to compositions comprising a hydrogel material that comprises a glycosaminoglycan polymer, adipose tissue and a compound of the structure The composition is administered to a site of a soft tissue condition including those of breast tissue. The hydrogel material can be porous or of solid particles. The glycosaminoglycan polymer can be a hyaluronan polymer.
    Type: Grant
    Filed: February 16, 2012
    Date of Patent: November 11, 2014
    Assignee: Allergan Inc.
    Inventors: Dennis E. Van Epps, Guang-Liang Jiang, Wha Bin Im
  • 1, 2, 4-oxadiazoles azetidine derivatives as sphingosine-1 phosphate receptors modulators
    Patent number: 8859598
    Abstract: The present invention relates to 1,2,4-oxadiazoles azetidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: October 14, 2014
    Assignee: Allergan, Inc.
    Inventors: Janet A. Takeuchi, Ling Li, Wha-Bin Im, Ken Chow
  • 2-thio-1,3,4-oxadiazoles azetidine derivatives as sphingosine-1 phosphate receptors modulators
    Patent number: 8846729
    Abstract: The present invention relates to 2-thio-1,3,4-oxadiazoles azetidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: September 30, 2014
    Assignee: Allergan, Inc.
    Inventors: Janet A. Takeuchi, Ling Li, Wha-Bin Im, Ken Chow
  • Oxadiazole derivatives as sphingosine 1-phosphate (S1P) receptor modulators
    Patent number: 8846728
    Abstract: The present invention relates to novel oxadiazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: June 26, 2013
    Date of Patent: September 30, 2014
    Assignee: Allergan, Inc.
    Inventors: Wenkui K. Fang, Evelyn G. Corpuz, Wha-Bin Im, Ken Chow, Liming Wang
  • SUBSTITUTED ARYL 1 ,2,4-OXADIAZOLES DERIVATIVES AS SPHINGOSINE-1 PHOSPHATE RECEPTORS MODULATORS
    Publication number: 20140274963
    Abstract: The present invention relates to substituted aryl 1,2,4-oxadiazoles derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Application
    Filed: March 18, 2014
    Publication date: September 18, 2014
    Applicant: Allergan, Inc.
    Inventors: Janet A. Takeuchi, Ling Li, Wha Bin Im, Ken Chow