Patents by Inventor Wilfred J. Samson

Wilfred J. Samson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6669674
    Abstract: The present invention discloses a multi-access cannula for use in a variety of surgical procedures, particularly for use in the course of performing conventional open-chest and peripheral access cardiopulmonary bypass (CPB). The multi-access cannula is capable of being inserted through a single puncture site with a percutaneous tip. At the appropriate depth of insertion, a closure seal may be engaged at the point of entry to secure the positioning of the cannula and prevent leakage of blood from the incision. Once the cannula is at the appropriate position the cannula provides a multiplicity of procedural options for the surgeon. For example, when approaching through the ascending aorta, the multi-access cannula enables the simultaneous passage of various fluids and multiple catheters or instruments in opposing directions within the lumen of the aortic arch through a single insertion site.
    Type: Grant
    Filed: May 8, 2000
    Date of Patent: December 30, 2003
    Assignee: Cardeon Corporation
    Inventors: John A. Macoviak, Wilfred J. Samson, Lynn M. Thompson, James J. Leary
  • Publication number: 20030236496
    Abstract: A method and device for perfusing an organ system is provided. The device may be further described as a catheter or cannula with an expandable flow control member positioned of the distal portion of the catheter shaft. The flow control member has a porous portion, and at least one impermeable portion, which prevent fluid from flowing out the ends of the flow control member. The flow control member is further characterized as having an interior chamber that is in fluid communication with a perfusion lumen that extends along the length of the catheter shaft and is in fluid communication with an external perfusion pump. The perfusion lumen is configured for providing flow to the interior of the flow control member, to create radial expansion thereof and to provide adequate flow to the arch vessels through said porous portion to sustain the metabolic demands of the brain.
    Type: Application
    Filed: March 18, 2003
    Publication date: December 25, 2003
    Inventors: Wilfred J. Samson, John A. Macoviak
  • Publication number: 20030138350
    Abstract: A circulatory support system and method for circulatory support are described for performing cardiopulmonary bypass using differential perfusion and/or isolated segmental perfusion of the circulatory system. The circulatory support system includes one or more venous cannulae for draining blood from the venous side of the patient's circulatory system, one or more arterial cannulae for perfusing the arterial side of the patient's circulatory system, and one or more blood circulation pumps connected between the venous cannulae and the arterial cannulae. The arterial cannulae and the venous cannulae of the circulatory support system may take one of several possible configurations. The circulatory support system is configured to segment a patient's circulatory system into one or more isolated circulatory loops.
    Type: Application
    Filed: November 27, 2002
    Publication date: July 24, 2003
    Inventors: John MacOviak, Wilfred J. Samson, Steve Baker, James J. Leary
  • Patent number: 6585689
    Abstract: The present invention provides an aortic catheter having an upstream occlusion member positioned in the ascending aorta between the coronary arteries and the brachiocephalic artery and a downstream anchoring member positioned in the descending aorta, downstream of the aortic arch. The upstream occlusion member is in the form of a narrow, disk-shaped inflatable balloon. The downstream anchoring member may be a larger inflatable balloon or other anchoring structure that provides sufficient friction to prevent migration of the balloon catheter in the upstream or downstream direction. In addition, an arch perfusion lumen, a corporeal perfusion lumen and a cardioplegia lumen are provided for performing selective perfusion and cardioplegic arrest.
    Type: Grant
    Filed: September 11, 2000
    Date of Patent: July 1, 2003
    Assignee: Cardeon Corporation
    Inventors: John A. Macoviak, Wilfred J. Samson, Steve G. Baker, Karl Van Dyk
  • Patent number: 6547760
    Abstract: A method and device for perfusing an organ system is provided. The device may be further described as a catheter or cannula with an expandable flow control member positioned of the distal portion of the catheter shaft. The flow control member has a porous portion, and at least one impermeable portion, which prevent fluid from flowing out the ends of the flow control member. The flow control member is further characterized as having an interior chamber that is in fluid communication with a perfusion lumen that extends along the length of the catheter shaft and is in fluid communication with an external perfusion pump. The perfusion lumen is configured for providing flow to the interior of the flow control member, to create radial expansion thereof and to provide adequate flow to the arch vessels through said porous portion to sustain the metabolic demands of the brain.
    Type: Grant
    Filed: August 3, 1999
    Date of Patent: April 15, 2003
    Assignee: Cardeon Corporation
    Inventors: Wilfred J. Samson, John A. Macoviak
  • Publication number: 20030036728
    Abstract: A method and device for perfusing an organ system is provided. The device may be further described as a catheter or cannula with an expandable flow control member positioned of the distal portion of the catheter shaft. The flow control member has a porous portion, and at least one impermeable portion, which prevent fluid from flowing out the ends of the flow control member. The flow control member is further characterized as having an interior chamber that is in fluid communication with a perfusion lumen that extends along the length of the catheter shaft and is in fluid communication with an external perfusion pump. The perfusion lumen is configured for providing flow to the interior of the flow control member, to create radial expansion thereof and to provide adequate flow to the arch vessels through said porous portion to sustain the metabolic demands of the brain.
    Type: Application
    Filed: October 8, 2002
    Publication date: February 20, 2003
    Inventors: Wilfred J. Samson, John A. Macoviak
  • Patent number: 6508777
    Abstract: A circulatory support system and method for circulatory support are described for performing cardiopulmonary bypass using differential perfusion and/or isolated segmental perfusion of the circulatory system. The circulatory support system includes one or more venous cannulae for draining blood from the venous side of the patient's circulatory system, one or more arterial cannulae for perfusing the arterial side of the patient's circulatory system, and one or more blood circulation pumps connected between the venous cannulae and the arterial cannulae. The arterial cannulae and the venous cannulae of the circulatory support system may take one of several possible configurations. The circulatory support system is configured to segment a patient's circulatory system into one or more isolated circulatory loops.
    Type: Grant
    Filed: May 6, 1999
    Date of Patent: January 21, 2003
    Assignee: Cardeon Corporation
    Inventors: John Macoviak, Wilfred J. Samson, Steve Baker, James J. Leary
  • Publication number: 20020169437
    Abstract: The invention is a catheter with a fluid flow divider positioned near the distal end of the catheter for dividing a first lumen into two channels at a point where a second lumen branches from the first lumen, and for selectively perfusing the branch lumen. The invention is particularly suited for use in the aortic arch. The fluid flow divider may comprise one or more inflatable chambers or one or more deployable shrouds comprising a plurality of arms with a webbing extending between adjacent arms. The inflatable chambers may be relatively noncompliant or they may be compliant, exhibiting elastic behavior after initial inflation, to closely fit the aortic lumen size and curvature. The catheter may further include one or more additional or auxiliary flow control members located upstream or downstream from the fluid flow divider to further segment the patient's circulatory system for selective perfusion to different organ systems within the body or to assist in anchoring the catheter in a desired position.
    Type: Application
    Filed: April 16, 2002
    Publication date: November 14, 2002
    Inventors: John A. Macoviak, Wilfred J. Samson
  • Publication number: 20020161351
    Abstract: An apparatus and method are described for therapeutic hypothermia of the heart by selective hypothermic perfusion of the myocardium through the patient's coronary arteries. The apparatus and method provide rapid cooling of the affected myocardium to achieve optimal myocardial salvage in a patient experiencing acute myocardial infarction. The therapeutic hypothermia system includes one or more selective coronary perfusion catheters and a fluid source for delivering a hypothermically-cooled physiologically-acceptable fluid, such as saline solution, oxygenated venous blood, autologously-oxygenated arterial blood and/or an oxygenated blood substitute. The system may also include one or more guidewires, subselective catheters and/or interventional catheters introduced through a lumen in the selective coronary perfusion catheter.
    Type: Application
    Filed: March 19, 2002
    Publication date: October 31, 2002
    Inventors: Wilfred J. Samson, John A. Macoviak, Janine Robinson, Brady Esch
  • Publication number: 20020161394
    Abstract: A aortic filter catheter is used to capture potential emboli within the aorta during heart surgery and cardiopulmonary bypass. An expandable embolic filter assembly having fine filter mesh for capturing macroemboli and microemboli is mounted on a catheter shaft having a perfusion lumen with perfusion ports located upstream of the filter. The embolic filter assembly can be actively or passively deployed within the ascending aortic. The embolic filter assembly includes an aortic occlusion device, which may be a toroidal balloon, an expandable balloon or a selectively deployable external catheter flow control valve. The combined device allows percutaneous transluminal administration of cardiopulmonary bypass and cardioplegic arrest with protection from undesirable embolic events.
    Type: Application
    Filed: March 26, 2002
    Publication date: October 31, 2002
    Inventors: John A. Macoviak, James J. Leary, Wilfred J. Samson
  • Publication number: 20020143362
    Abstract: The present invention is related to cerebral embolic protection assemblies (CEPA) to be used during a medical procedure to help redirect or catch emboli before it is pumped into the cerebral circulation. A variety of CEPA's are disclosed including a perfusion filter catheters and fluid flow dividers for capturing and redirecting potential emboli within the aorta during heart surgery and cardiopulmonary bypass. The catheter devices may further include one or more additional or auxiliary flow control members. Furthermore, oxygenated blood is perfused through a perfusion lumen in the catheter. The present invention describes devices that are capable of capturing and/or redirected emboli away from the cerebral circulation. The devices are configured for percutaneous, intercostal, lateral or central insertion with attendant administration of cardiopulmonary bypass and cardioplegic arrest with protection from undesirable embolic events.
    Type: Application
    Filed: May 28, 2002
    Publication date: October 3, 2002
    Inventors: John A. Macoviak, Wilfred J. Samson
  • Patent number: 6395014
    Abstract: The present invention is related to cerebral embolic protection assemblies (CEPA) to be used during a medical procedure to help redirect or catch emboli before it is pumped into the cerebral circulation. A variety of CEPA's are disclosed including a perfusion filter catheters and fluid flow dividers for capturing and redirecting potential emboli within the aorta during heart surgery and cardiopulnonary bypass. The catheter devices may further include one or more additional or auxiliary flow control members. Furthermore, oxygenated blood is perfused through a perfusion lumen in the catheter. The present invention describes devices that are capable of capturing and/or redirected emboli away from the cerebral circulation. The devices are configured for percutaneous, intercostal, lateral or central insertion with attendant administration of cardiopulmonary bypass and cardioplegic arrest with protection from undesirable embolic events.
    Type: Grant
    Filed: November 22, 1999
    Date of Patent: May 28, 2002
    Inventors: John A. Macoviak, Wilfred J. Samson
  • Patent number: 6371935
    Abstract: The invention is a catheter with a fluid flow divider positioned near the distal end of the catheter for dividing a first lumen into two channels at a point where a second lumen branches from the first lumen, and for selectively perfusing the branch lumen. The invention is particularly suited for use in the aortic arch. The fluid flow divider may comprise one or more inflatable chambers or one or more deployable shrouds comprising a plurality of arms with a webbing extending between adjacent arms. The inflatable chambers may be relatively noncompliant or they may be compliant, exhibiting elastic behavior after initial inflation, to closely fit the aortic lumen size and curvature. The catheter may further include one or more additional or auxiliary flow control members located upstream or downstream from the fluid flop divider to further segment the patient's circulatory system for selective perfusion to different organ systems within the body or to assist in anchoring the catheter in a desired position.
    Type: Grant
    Filed: August 20, 1999
    Date of Patent: April 16, 2002
    Assignee: Cardeon Corporation
    Inventors: John A. Macoviak, Wilfred J. Samson
  • Patent number: 6361545
    Abstract: A perfusion filter catheter is used to capture potential emboli within the aorta during heart surgery and cardiopulmonary bypass. An expandable embolic filter assembly having fine filter mesh for capturing macroemboli and microemboli is mounted on a catheter shaft having a perfusion lumen with perfusion ports located upstream of the filter. The embolic filter assembly can be actively or passively deployed within the ascending aortic. An optional outer tube covers the embolic filter assembly to prevent premature deployment. Radiopaque markers, sonoreflective markers and/or an aortic transillumination system are provided to monitor the position of the catheter and the deployment state of the embolic filter assembly. The embolic filter assembly is configured to maximize the effective filter surface area when deployed.
    Type: Grant
    Filed: September 22, 1998
    Date of Patent: March 26, 2002
    Assignee: Cardeon Corporation
    Inventors: John A. Macoviak, James J. Leary, Wilfred J. Samson
  • Publication number: 20020010411
    Abstract: An aortic shunt apparatus and methods for cerebral embolic protection are described for isolating the aortic arch vessels from the aortic lumen, for selectively perfusing the arch vessels with a fluid and for redirecting blood flow within the aortic lumen and any potential embolic materials carried in the blood through a shunt past the isolated arch vessels. The perfusion shunt apparatus may be mounted on a catheter or cannula for percutaneous introduction or for direct insertion into the aorta. The perfusion shunt apparatus has application for protecting a patient from embolic stroke and hypoperfusion during cardiopulmonary bypass or cardiac surgery and also for selectively perfusing the cerebrovascular circulation with oxygenated blood or with neuroprotective fluids in the presence of risk factors, such as head trauma or cardiac insufficiency. The perfusion shunt apparatus will also find application for selective perfusion of other organ systems within the body.
    Type: Application
    Filed: July 3, 2001
    Publication date: January 24, 2002
    Inventors: John A. Macoviak, Wilfred J. Samson, James J. Leary, Brady D. Esch
  • Publication number: 20010047163
    Abstract: The present invention relates to a catheter or cannula system that facilitates cardiopulmonary bypass surgeries and enables prolonged circulatory support of the heart. More specifically, the present invention provides an aortic catheter system including a porous aortic root balloon capable of occluding the aorta, delivering cardioplegia and providing tactile feedback and helping to maintain the competency of regurgitant aortic valves.
    Type: Application
    Filed: July 31, 2001
    Publication date: November 29, 2001
    Inventors: Wilfred J. Samson, Janine Robinson, Steve Baker, James J. Leary
  • Patent number: 6267747
    Abstract: The present invention relates to a catheter or cannula system that facilitates cardiopulmonary bypass surgeries and enables prolonged circulatory support of the heart. More specifically, the present invention provides an aortic catheter system including a porous aortic root balloon capable of occluding the aorta, delivering cardioplegia and providing tactile feedback and helping to maintain the competency of regurgitant aortic valves.
    Type: Grant
    Filed: May 6, 1999
    Date of Patent: July 31, 2001
    Assignee: Cardeon Corporation
    Inventors: Wilfred J. Samson, Janine Robinson, Steve Baker, James J. Leary
  • Patent number: 6254563
    Abstract: A perfusion shunt apparatus and methods are described for isolating and selectively perfusing a segment of a patient's cardiovascular system and for directly circulatory flow around the isolated segment. An aortic perfusion shunt apparatus is configured for deployment within a patient's aortic arch and methods are described for isolating the aortic arch vessels from the aortic lumen, for selectively perfusing the arch vessels with a fluid and for directly blood flow within the aortic lumen through a shunt past the isolated arch vessels. The perfusion shunt apparatus may be mounted on a catheter or cannula for percutaneous introduction or for direct insertion into a circulatory vessel, such as the aorta.
    Type: Grant
    Filed: March 20, 2000
    Date of Patent: July 3, 2001
    Assignee: Cardeon Corporation
    Inventors: John A. Macoviak, Wilfred J. Samson, James J. Leary, Brady D. Esch
  • Patent number: 6139517
    Abstract: A perfusion shunt apparatus and methods are described for isolating and selectively perfusing a segment of a patient's cardiovascular system and for directing circulatory flow around the isolated segment. An aortic perfusion shunt apparatus is configured for deployment within a patient's aortic arch and methods are described for isolating the aortic arch vessels from the aortic lumen, for selectively perfusing the arch vessels with a fluid and for directing blood flow within the aortic lumen through a shunt past the isolated arch vessels. The perfusion shunt apparatus may be mounted on a catheter or cannula for percutaneous introduction or for direct insertion into a circulatory vessel, such as the aorta.
    Type: Grant
    Filed: December 14, 1998
    Date of Patent: October 31, 2000
    Assignee: Cardeon Corporation
    Inventors: John A. Macoviak, Wilfred J. Samson, James J. Leary, Brady D. Esch
  • Patent number: 6117105
    Abstract: The present invention provides an aortic catheter having an upstream occlusion member positioned in the ascending aorta between the coronary arteries and the brachiocephalic artery and a downstream anchoring member positioned in the descending aorta, downstream of the aortic arch. The upstream occlusion member may be an inflatable balloon or a selectively deployable external catheter valve. The downstream anchoring member may be a larger inflatable balloon or other anchoring structure that provides sufficient friction to prevent migration of the balloon catheter in the upstream or downstream direction. In addition, an arch perfusion lumen, a corporeal perfusion lumen and a cardioplegia lumen are provided for performing selective perfusion and cardioplegic arrest.
    Type: Grant
    Filed: December 4, 1998
    Date of Patent: September 12, 2000
    Assignee: Cardeon Corporation
    Inventors: John F. Bresnaham, John A. Macoviak, Wilfred J. Samson, Steve G. Baker, Karl Van Dyk