Patent number: 6172225
Abstract: The invention relates to a novel process for producing thereof hydroxyarenes of the general formula (I)
in which
n represents the numbers 1, 2, 3 or 4,
R represents cyano, carboxyl, formyl, nitro, halogen or represents alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, alkylcarbonyl or alkoxycarbonyl, each of which is optionally substituted, and
Z represents hydrogen, cyano, nitro, halogen, alkyl, halogenoalkyl, or represents monocyclic or bicyclic, saturated or unsaturated heterocyclyl, heterocyclylamino or heterocyclylimino, each of which is optionally substituted,
characterized in that halogenoarenes of the general formula (II)
in which
n, R and Z are each as defined above and
X represents halogen
are reacted with 3-hydroxy-propionitrile of the formula (III),
HO—CH2CH2—CN (III),
if appropriate in the presence of a reaction auxiliary and if appropriate in the presence of a diluent, at temperatures between 0° C. and 100° C.
Type:
Grant
Filed:
November 12, 1998
Date of Patent:
January 9, 2001
Assignee:
Bayer Aktiengesellschaft
Inventors:
Karl-Heinz Linker, Wilhelm Haas, Otto Schallner, Kurt Findeisen, Roland Andree, Mark Wilhelm Drewes