Abstract: Structural modules may be produced through additive manufacturing. The modules may comprise interconnecting features to couple modules together, structural support members, external layers, and/or integrated electrical connectivity. The modules may be produced through a coreactive additive manufacturing system comprising a movable printing arm and/or a movable table.

Abstract: A sensing system implements one or more MEMS microphones in order to measure mechanical waves. The sensing system can be part of a larger system used to determine motion and position of a user's hand or other body part. The MEMS microphones can be part of a plurality of MEMS microphones. There may additionally be MEMS microphones that transmit mechanical waves at certain frequencies that can be measured by the MEMS microphones and subsequently distinguished from other mechanical waves and used to determine additional information regarding movement and position.

Abstract: Reactive additive manufacturing compositions with low amounts of noncombustible materials are provided, as well as methods of making and using the compositions. The compositions comprise two or more reactive components and a filler.

Abstract: The present disclosure involves systems, software, and computer implemented methods for automatically providing linking partner loyalty rewards accounts using authorized user and primary user information associated with an account. One example method includes authenticating a user at a partner system, and receiving from the user information associated with an account. The information associated with user's account is communicated to a financial institution system via an API where the user can then be verified as an authorized user on an account. The financial institution system then provides the partner system with information associated with the primary user of the account, and the partner system can link a loyalty account of the primary user with the loyalty account of the authenticated user.

Abstract: The disclosure relates to Larotrectinib and salts thereof for use in a method for treating a patient having a cancer characterized by a neurotrophic receptor kinase gene fusion, wherein the patient has received and will receive a moderate CYP3A4 inducer to improve the anti-cancer efficacy of larotrectinib and salts thereof in patients taking one or more CYP3A4 modulating drugs.

Abstract: Provided are vaccines, polypeptides and polynucleotides based on mutant CALR and JAK2 sequences, vectors, host cells, viruses, and methods of making and using them. The disclosure also provides methods of inducing an immune response and methods of treating, preventing, reducing a risk of onset or delaying the onset of a clinical condition characterized by an expression of JAK2V617F or CALR exon 9 mutant, or both JAK2V617F and CALR exon 9 mutant, wherein the method comprises a plurality of administrations of any of the compositions comprising polynucleotides, polypeptides or vectors disclosed herein.

Abstract: A charging station for charging the battery of a vehicle includes: a base portion configured for mounting in a substructure; a charging portion having a charging outlet for connection to a vehicle; and a retraction mechanism for moving the charging portion between an extended position in which it extends out of the base portion and a retracted position; and a controller for controlling the retraction mechanism; the controller being configured to: determine whether a predetermined period of time has elapsed since the most recent charging from the charging outlet ceased; and cause the retraction mechanism to move the charging portion to the retracted position if the predetermined period of time is determined to have elapsed since the most recent electrical supply from the outlet.

Abstract: Described are compositions including: (a) a polymeric dispersant including: (i) an average of at least two polyether pendant groups per molecule; and (ii) an average of at least two amine groups per molecule; and (b) a functionalized acid component including sulfonic acid and/or phosphoric acid functionalized with at least one of an aromatic functional group or a fatty functional group; and wherein at least about 60 percent of the amine groups present in the polymeric dispersant are each individually neutralized with a molecule of the functionalized acid component. Also described are pigment dispersions and/or ink formulations including these compositions, as well as various methods of making and/or using the compositions, pigment dispersions, and/or ink formulations.

Abstract: Systems and methods are disclosed herein for detecting a first reaction by a user when consuming a media asset at a first time, where a first magnitude of the first reaction exceeds a first threshold. The systems and methods may determine whether a second reaction by the user occurred when the user consumed the media asset at a second time that is prior to the first time, where a second magnitude of the second reaction exceeds a second threshold, and may recommend the second media asset to the user.

Abstract: Methods and apparatuses are described for intelligent imputation of missing data in a machine learning (ML) dataset comprised of a plurality of features. Each feature includes a plurality of values, where at least a portion of the values for one or more features are missing. A server analyzes the ML dataset to generate characteristics of the missing values in the ML dataset. The server selects an imputation algorithm for filling in the missing values based upon the identified characteristics. The server determines a computing environment in which the imputation algorithm is executed based upon one or more of a size of the ML dataset or the selected algorithm. The server generates code that comprises instructions for executing the imputation algorithm on the ML dataset in the computing environment. The server integrates the code into an ML platform that executes the code to assign replacement values to the missing values.

Abstract: In a method of molecular scaffold hopping an interface of a scheduler computer sends instructions, prepared by the scheduler computer, to a job runner computer to perform a plurality of separate computational tasks. Each of the separate computational tasks includes calculating one or more chemical properties for a query molecule or molecules in a library of molecules. One or more of the plurality of separate computational tasks performed on the job runner computer are preemptible computing instances. Status indicators sent from the job runner computer are received by the interface for each of the plurality of separate computational tasks. The indicators are one of: incomplete, completed, or failed computing instances. The interface resends the instructions to the job runner computer that correspond to the separate computational tasks having the failed computing instance indicator to increase fault-tolerance against the separate computational tasks not attaining the completed computing instance indicator.

Abstract: Improvements in devices for animals, such as animal tag applicators, animal tissue sample extractors, and animal puncture devices, comprising: a first body portion comprising: a first jaw portion configured to engage a first portion of an animal tag; a first handle portion; and a first central portion between the first jaw portion and the first handle portion; a second body portion comprising: a second jaw portion configured to engage a second portion of an animal tag; a second handle portion; and a second central portion between the second jaw portion and the second handle portion; and a clamp bush configured to retain the first central portion and the second central portion together; wherein an outer face of the first central portion comprises a border around an outer edge of the outer face of the first central portion and the outer face of the second central portion comprises a border around an outer edge of the outer face of the first central portion.

Abstract: A permanent magnet generator (PMG) system can include a stator configured to output a voltage, and a rotor assembly configured to be magnetically coupled to the stator and to rotate relative to the stator to induce the voltage. The rotor assembly can be configured to passively attenuate the voltage output from the stator in response to acceleration of the rotor assembly at or above an impulse acceleration threshold.

Abstract: An assembly comprises a resistor support housing for a rotating rectifier assembly (RRA). A shaft bore is defined through the resistor support housing for passage of a shaft of an electrical machine. The resistor support housing defines a main annular body around the shaft bore. An end housing is mounted to one axial end of the resistor support housing. The end housing defines a portion of the shaft bore therethrough.

Abstract: The present invention provides recombinant TIM-4 fusion proteins comprising an extracellular domain of TIM-4 and at least one co-stimulatory domain. Also provided are cells comprising the fusion protein and methods of making and using the same.

Abstract: Systems and methods are described, and an example system includes an AI enhanced multi-source health data integration logic that receives a first source electronic health record (EHR) data from a first EHR system and a second source EHR data from a second EHR system, and transforms, according to a knowledge representation schema, health-related information content of the first source EHR data and the second source EHR data to a first source transformed health data and second source transformed health data. The system includes a collaboration platform, configured to host a multi-source transformed health data database, including the transformed first source health data and the transformed second source health data, and hosts AI-enhanced, multiple level telecollaborative analyses by a plurality of participants of the multi-source transformed health data database, generating health management data.

Abstract: An engraving machine is disclosed. The engraving machine may have a housing and an engraver located within the housing. The engraving machine may have a slot disposed on the housing for receiving a cartridge including an offboard item to be engraved. The engraving machine may have an onboard storage configured to store a plurality of tags. The engraving machine may have a carrier for receiving the cartridge through the slot and for positioning the cartridge relative to the engraver. The engraving machine may have a pick mechanism for selectively retrieving a tag from the tags stored in the onboard storage and for positioning the tag relative to the engraver. The engraver may engrave the offboard item or the tag based on a user selection.

Abstract: An aircraft engine repair tool for installing and/or removing a mid turbine frame from a gas turbine engine is provided. The tool includes a stabilizer configured to support a shaft via a load path different from a load path provided by the mid turbine frame rotatably supporting the shaft about a rotation axis. The tool includes a holder attachable to the mid turbine frame, and a guide movably engageable with the shaft and attachable to the holder. The guide guides movement of the holder and of the mid turbine frame relative to the shaft along the rotation axis, and prevents movement of the holder and the mid turbine frame relative to the shaft transverse to the rotation axis when the mid turbine frame is released from the support structure and attached to the holder, and when the holder is attached to the guide.

Abstract: A sensor device includes a sensor arranged to produce time domain data representative of a sensed time dependent characteristic adjacent the sensor, and a signal processing component. The signal processing component is arranged to use the time domain data to produce frequency domain data indicative of frequency components present in the time domain data. The sensor device also includes a data transmission component arranged to transmit at least a portion of the frequency domain data. The sensor device is arranged to select a subset of frequency domain data corresponding to a defined number of highest peaks in the frequency domain data and to transmit the selected subset of frequency domain data.