Patents by Inventor William A. Grissom

William A. Grissom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200273175
    Abstract: A system and method to analyze image data. The image data may be used to assist in determine the presence of a feature in the image. The feature may include a bubble.
    Type: Application
    Filed: February 21, 2019
    Publication date: August 27, 2020
    Inventors: Christine R. Drown, Andrew Wald, Rebecca L. Vincelette, William A. Grissom
  • Publication number: 20200268434
    Abstract: A system and method to analyze image data. The image data may be used to assist in determine the presence of a feature in the image. The feature may include a bubble.
    Type: Application
    Filed: February 21, 2019
    Publication date: August 27, 2020
    Inventors: Christine R. Drown, Andrew Wald, Rebecca L. Vincelette, William A. Grissom
  • Patent number: 9995808
    Abstract: Systems and methods for performing MRI include using a RF gradient field for spatial encoding. In particular implementations, |B+i|-selective pulses designed using the Shinnar-Le Roux algorithm can be provided as the excitation pulse for the RF gradient field. Further, frequency encoding for the RF gradient field can be based on the Bloch-Siegert (BS) shift. Together, these techniques can be used to support MRI based on RF gradient encoding instead of the conventional Bo encoding.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: June 12, 2018
    Assignee: VANDERBILT UNIVERSITY
    Inventors: William Grissom, Mark Does, Zhipeng Cao
  • Patent number: 9579042
    Abstract: A system and method for MR imaging is disclosed. The method causes an RF coil assembly and plurality of gradient coils to apply a fast spin echo (FSE) pulse sequence comprising a preparation segment and a plurality of refocusing segments. The FSE pulse sequence generates a pair of echoes is generated in each of the plurality of refocusing segments that comprises a first echo generated by magnetization pathways having an even number of phase inversions and a second echo generated by magnetization pathways having an even number of phase inversions. MR signals are acquired from the first echo and the second echo and an image of at least a portion of a subject of interest is reconstructed from the acquired MR signals.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: February 28, 2017
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Yuval Zur, William Grissom
  • Publication number: 20150320335
    Abstract: A system and method for MR imaging is disclosed. The method causes an RF coil assembly and plurality of gradient coils to apply a fast spin echo (FSE) pulse sequence comprising a preparation segment and a plurality of refocusing segments. The FSE pulse sequence generates a pair of echoes is generated in each of the plurality of refocusing segments that comprises a first echo generated by magnetization pathways having an even number of phase inversions and a second echo generated by magnetization pathways having an even number of phase inversions. MR signals are acquired from the first echo and the second echo and an image of at least a portion of a subject of interest is reconstructed from the acquired MR signals.
    Type: Application
    Filed: July 20, 2015
    Publication date: November 12, 2015
    Inventors: Yuval Zur, William Grissom
  • Publication number: 20150253403
    Abstract: Embodiments of the invention concern systems and methods for performing MRI using RF gradients for spatial encoding. One aspect of the invention involves providing |B1+|-selective pulses designed using the Shinnar-Le Roux algorithm. Another aspect of the invention involves RF encoding based on the Bloch-Siegert (BS) shift. Together, these techniques can be used to support MRI based on RF gradient encoding instead of the conventional B0 encoding.
    Type: Application
    Filed: March 10, 2015
    Publication date: September 10, 2015
    Inventors: William Grissom, Mark Does, Zhipeng Cao
  • Patent number: 9119955
    Abstract: A system and method for focusing ultrasound into a target tissue is disclosed. The method calculates a pressure field for an array of transducer elements to generate an unaberrated pressure field matrix and causes the transducer elements to apply focused ultrasound to generate a respective aberrated pressure field at a focus location in a target tissue and surrounding volume. MR-ARFI images are acquired of the focus location and surrounding volume, a magnitude of the aberrated pressure field is measured that is generated by the applied focused ultrasound at respective focus locations in the target tissue and surrounding volume based on the MR-ARFI images, an aberration for the transducer elements is determined from the pressure field matrix and the MR-ARFI images of the focus location and the surrounding volume using a magnitude least-squares method, and a corrective phase/amplitude adjustment is applied to the transducer elements based on the determined aberrations.
    Type: Grant
    Filed: May 23, 2013
    Date of Patent: September 1, 2015
    Assignee: General Electric Company
    Inventors: Yuval Zur, William Grissom
  • Publication number: 20140350439
    Abstract: A system and method for focusing ultrasound into a target tissue is disclosed. The method calculates a pressure field for an array of transducer elements to generate an unaberrated pressure field matrix and causes the transducer elements to apply focused ultrasound to generate a respective aberrated pressure field at a focus location in a target tissue and surrounding volume. MR-ARFI images are acquired of the focus location and surrounding volume, a magnitude of the aberrated pressure field is measured that is generated by the applied focused ultrasound at respective focus locations in the target tissue and surrounding volume based on the MR-ARFI images, an aberration for the transducer elements is determined from the pressure field matrix and the MR-ARFI images of the focus location and the surrounding volume using a magnitude least-squares method, and a corrective phase/amplitude adjustment is applied to the transducer elements based on the determined aberrations.
    Type: Application
    Filed: May 23, 2013
    Publication date: November 27, 2014
    Applicant: General Electric Company
    Inventors: Yuval Zur, William Grissom
  • Patent number: 8810246
    Abstract: Proton resonance frequency shift thermometry may be improved by combining multibaseline and referenceless thermometry.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: August 19, 2014
    Assignees: Insightec Ltd., The Board of Trustees of The Leland Stanford Junior University
    Inventors: William A. Grissom, Kim Butts Pauly, Michael Lustig, Yoav Medan, Yoav Levy, Viola Rieke
  • Patent number: 8749234
    Abstract: Methods and systems for designing excitation pulses for magnetic resonance imaging are provided. One method includes parameterizing spin-domain rotation parameters to define parameterized variables and defining a constrained optimization problem based on the parameterized variables. The method also includes solving the constrained optimization problem and generating parameters for the RF pulses based on the solved problem, wherein the RF pulses are one of multidimensional RF pulses on non-constant gradient trajectories or one dimensional RF pulses on non-constant gradient trajectories.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: June 10, 2014
    Assignee: General Electric Company
    Inventor: William Grissom
  • Patent number: 8558547
    Abstract: A system and method for radio-frequency (RF) field mapping are provided. One method includes encoding a B1 phase in at least one magnetic resonance (MR) excitation pulse as an encoded B1 phase MR excitation pulse for at least a subset of a plurality of transmit channels within a magnetic resonance imaging (MRI) system. The method also includes encoding a B1 magnitude in at least one off-resonance MR pulse as an encoded B1 magnitude off-resonance MR pulse for at least a subset of the plurality of transmit channels within the MRI system. The method further includes determining one or more composite B1 fields resulting from a transmission of the at least one encoded B1 phase MR excitation pulse and the at least one encoded B1 magnitude off-resonance MR pulse.
    Type: Grant
    Filed: May 5, 2011
    Date of Patent: October 15, 2013
    Assignee: General Electric Company
    Inventors: Laura Irene Sacolick, Mika Vogel, William Grissom, Guido Kudielka
  • Patent number: 8482285
    Abstract: The phase background of a proton resonance frequency shift treatment image may be estimated by fitting a combination of baseline images to the treatment image.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: July 9, 2013
    Assignees: Insightec Ltd., The Board of Trustees of The Leland Stanford Junior University
    Inventors: William A. Grissom, Kim Butts Pauly, Michael Lustig, Yoav Medan, Yoav Levy, Viola Rieke
  • Publication number: 20120280683
    Abstract: A system and method for radio-frequency (RF) field mapping are provided. One method includes encoding a B1 phase in at least one magnetic resonance (MR) excitation pulse as an encoded B1 phase MR excitation pulse for at least a subset of a plurality of transmit channels within a magnetic resonance imaging (MRI) system. The method also includes encoding a B1 magnitude in at least one off-resonance MR pulse as an encoded B1 magnitude off-resonance MR pulse for at least a subset of the plurality of transmit channels within the MRI system. The method further includes determining one or more composite B1 fields resulting from a transmission of the at least one encoded B1 phase MR excitation pulse and the at least one encoded B1 magnitude off-resonance MR pulse.
    Type: Application
    Filed: May 5, 2011
    Publication date: November 8, 2012
    Inventors: Laura Irene Sacolick, Mika Vogel, William Grissom, Guido Kudielka
  • Publication number: 20120194184
    Abstract: Methods and systems for designing excitation pulses for magnetic resonance imaging are provided. One method includes parameterizing spin-domain rotation parameters to define parameterized variables and defining a constrained optimization problem based on the parameterized variables. The method also includes solving the constrained optimization problem and generating parameters for the RF pulses based on the solved problem, wherein the RF pulses are one of multidimensional RF pulses on non-constant gradient trajectories or one dimensional RF pulses on non-constant gradient trajectories.
    Type: Application
    Filed: January 28, 2011
    Publication date: August 2, 2012
    Inventor: William Grissom
  • Publication number: 20110178386
    Abstract: The phase background of a proton resonance frequency shift treatment image may be estimated by fitting a combination of baseline images to the treatment image.
    Type: Application
    Filed: January 19, 2011
    Publication date: July 21, 2011
    Inventors: William A. Grissom, Kim Butts Pauly, Michael Lustig, Yoav Medan, Yoav Levy, Viola Rieke
  • Publication number: 20110175615
    Abstract: Proton resonance frequency shift thermometry may be improved by combining multibaseline and referenceless thermometry.
    Type: Application
    Filed: January 19, 2011
    Publication date: July 21, 2011
    Inventors: William A. Grissom, Kim Butts Pauly, Michael Lustig, Yoav Medan, Yoav Levy, Viola Rieke