Abstract: An information management problem definition system has a processing device configured for receiving a plurality of messages comprising a chat session from a plurality of users communicating via a plurality of workstations during a problem definition initiative conference session. The processing device is further configured for logging session data and event data comprising data corresponding to one or more messages received from one or more users during the chat session, archiving at least a portion of the logged event data, wherein the archived data is configured as searchable and retrievable data, and initiating an interface to one or more of the plurality of users including initiating display of at least one of the plurality of messages via the interface and initiating display of at least some of the event data and at least some of the session data via the interface.

Abstract: Systems and processes for managing data relating to one or more medical or biological conditions of a plurality of subjects (such as patients) over a wide area network, such as the Internet, may be employed for diabetes subjects or subjects with other medical conditions requiring monitoring and/or treatment over time. Such systems and processes provide various functions for several types of users, including patients or subject-users, healthcare provider-users and payor entity-users and combinations thereof, which allow for improved treatment and medical data management of individual subjects and groups of subjects and which allow collection and analysis of aggregate data from many subject sources, for improving overall healthcare practices of providers and subjects (e.g., patients).

Abstract: A surgical instrument comprises a member including an end. A first image guide is connected with the member and is oriented relative to a sensor to communicate a signal representative of a position of the member. A second image guide is connected with the member and is oriented relative to a sensor to communicate a signal representative of a position of the end relative to the member. Systems and methods are disclosed.

Abstract: Fusion polypeptides comprising a TRAIL trimer and a targeting domain are disclosed. The targeting domain can be, in some embodiments, a sequence that binds MUC16, which is prevalent on some tumor cells such as pancreatic and ovarian tumor cells. A sequence that binds MUC 16 can be mesothelin or a MUC16-binding fragment thereof, such as amino acids 1-64 of mesothelin. A fusion polypeptide of the present teachings can induce apoptosis in a target cell such as a MUC16-expressing cancer cell. Also disclosed are nucleic acids encoding the fusion polypeptides, and methods of use of the fusion polypeptides and nucleic acids.

Abstract: Chromatographic separation devices are described that include a chromatographic separation module and a memory component. The memory component is attached to the chromatographic separation module, contains information related to use history of the chromatographic separation module with respect to the entire lifetime of the module, and includes a write-once-read-many (WORM) area where the information is written and where the information, once written, cannot be deleted or modified.

Abstract: Systems, devices and methods for storage, delivery, receipt, and/or other handling of an item in an electronically controllable storage receptacle are disclosed. The disclosure provides features for keyless access to the storage receptacle by use of user access information, such as a PIN or bar code. Further, features are disclosed for receiving and/or transmitting data related to the recipient and the item to facilitate the various handling actions of the item.

Abstract: In one embodiment, the tablet connection system includes an attachment station configured to couple to a tablet, and a tablet attachment system configured to couple to the attachment station and the tablet. The attachment station includes a charging mechanism such that the attachment station is configured to charge the tablet and hold the tablet such that the tablet is positioned for viewing by a user. In one embodiment, the charging mechanism of the attachment station is configured to wirelessly charge the tablet that is coupled thereto. The tablet attachment system is configured to provide coupling between the tablet and the attachment station.

Abstract: An electrochemical device (such as a battery) includes at least one electrode having a fluid surface and one or more sensors configured to detect an operating condition of the device. Fluid-directing structures may modulate flow or retain fluid in response to the sensors. An electrolyte within the device may also include an ion-transport fluid, for example infiltrated into a porous solid support.

Abstract: The present invention features processes for preparing compounds, such as (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1), useful for treating CFTR mediated diseases such as cystic fibrosis.

Abstract: In one embodiment, a metric collection system may collect application metrics across multiple data centers in specific time intervals. A local collection point 108 may establish an absolute reference time for a local data center 102. The local collection point 108 may determine a source reporting interval for an application 106 based on the absolute reference time. The local collection point 108 may receive a source metric report 300 for the application 106 based on the source reporting interval.

Abstract: Patient care equipment includes a wireless coupler that transfers power and/or data between an architectural unit and the patient care equipment. The patient care equipment may also include additional wireless couplers that transfer power and/or data between first and second components of the equipment. The second component may be movable relative to the first component. A structure or hot swapping batteries is also disclosed, the swapped battery being charged on an inductive charging mat.

Abstract: A method for managing an inventory system includes receiving an operation request that identifies an inventory item and selecting, from a plurality of workstations, a workstation at which to fulfill the operation request. The method also includes moving an inventory holder storing the identified inventory item to the selected workstation and moving a supply holder storing a supply item associated with the received operation request to the selected workstation. The method additionally includes fulfilling the operation request, at least in part, at the workstation.

Abstract: Integrated computational elements having alternating layers of materials may be problematic to configure toward mimicking some regression vectors. Further, they sometimes may be inconvenient to use within highly confined locales. Integrated computational elements containing a quantum dot array may address these issues. Optical analysis tools with an integrated computational element can comprise: an electromagnetic radiation source that provides electromagnetic radiation to an optical pathway; an integrated computational element positioned within the optical pathway, the integrated computational element comprising a quantum dot array having a plurality of quantum dots disposed at a plurality of set array positions; and a detector that receives the electromagnetic radiation from the optical pathway after the electromagnetic radiation has optically interacted with a sample and the integrated computational element.

Abstract: Aspects of the subject disclosure may include, for example, a transmission medium that includes a dielectric core comprising a plurality of rigid dielectric members configured to propagate guided electromagnetic waves. A dielectric cladding is disposed on at least a portion of an outer surface of the first dielectric core. Other embodiments are disclosed.

Abstract: Systems and methods for an improved DDoS mitigation approach are provided. According to one embodiment, a current threshold for a network connection characteristic is established within a Denial-of-Service (DoS) mitigation device logically interposed between a protected resource of a private network and multiple client devices residing external to the private network. A number of connections between the client devices and the protected network resource are tracked. During a period of time in which the number of connections exceeds a connection count threshold: (i) for each of the connections, a measured value for the network connection characteristic is compared to the current threshold; (ii) responsive to a determination that the measured value exceeds the current threshold, the connection is dropped; and (iii) the current threshold is periodically reduced, such that only those connections complying with the current threshold are maintained.

Abstract: A method for treating or preventing a T-cell-mediated autoimmune disease is provided herein, the method including administering to a mammal in need thereof a therapeutically effective amount of soluble CD137 or CD137pos regulatory T cells. Also provided are pharmaceutical compositions for treating or preventing T-cell-mediated autoimmune diseases, the pharmaceutical compositions including a therapeutically effective amount of soluble CD137 or CD137pos regulatory T cells and a pharmaceutically-acceptable carrier.

Abstract: A method for managing information relating to a change deployment in order to communicate some or all the information to a plurality of users includes providing an interface to users at workstations accessible by the users, receiving information comprising a plurality of messages from users communicating via the workstations during a change deployment session, initiating display of at least one of the messages to the users via the interface, initiating display of task data to the users via the interface, the task data corresponding to at least one task necessary for completing the change deployment, logging event data related to a plurality of events associated with the change deployment conference session, the event data comprising task status data indicating the status of the at least one task necessary for completing the change deployment, and initiating display of at least some of the event data to the users via the interface.

Abstract: A power inverter (12) that is connectable with a mobile application via a wireless communication link (32). The mobile application enables operation of the power inverter (12) to be monitored and controlled via a graphical user interface on a remote device (34).