Abstract: This invention provides bicyclic carboxylic esters and amides, their pharmaceutical formulations, and a method for their use in treating migraine, emesis, gastrointestinal disorders, schizophrenia, or anxiety in mammals.

Abstract: This invention provides bicyclic carboxylic esters and amides, their pharmaceutical formulations, and a method for their use in treating migraine, emesis, gastrointestinal disorders, schizophrenia, or anxiety in mammals.

Abstract: This invention provides bicyclic carboxylic esters and amides, their pharmaceutical formulations, and a method for their use in treating migraine, emesis, gastrointestinal disorders, schizophrenia, or anxiety in mammals.

Abstract: This invention provides bicyclic carboxylic esters and amides, their pharmaceutical formulations, and a method for their use in treating migraine, emesis, gastrointestinal disorders, schizophrenia, or anxiety in mammals.

Abstract: This invention provides bicyclic carboxylic esters and amides, their pharmaceutical formulations, and a method for their use in treating migraine, emesis, gastrointestinal disorders, schizophrenia, or anxiety in mammals.

Abstract: Fluorenes bearing a 9-aminoalkyl substituent are useful antiarrhythmic agents. Pharmaceutical formulations containing such compounds are provided, as well as a method of treatment.

Abstract: This invention relates to certain amino-5,6-diaryl-1,2,4-triazines and -pyrazines useful as activators of GABA and benzodiazepine binding.

Abstract: 9-Carbamoyl-9-(2-cyanoethyl)fluorenes are converted to 9-carbamoyl-9-(3-aminopropyl)fluorenes by catalytic hydrogenation in the presence of a strong acid.

Abstract: This invention relates to certain amino-5,6-diarylpyrazines useful as activators of GABA and benzodiazepine binding.

Abstract: 9-(N-alkanoylaminoalkyl)-fluorenes are anti-arrhythmic agents.

Abstract: 9-Carbamoylfluorene derivatives are useful intermediates in a synthesis of 9-carbamoyl-9-(3-aminopropyl)fluorene antiarrhythmic agents.

Abstract: Fluorenes bearing a 9-aminoalkyl substituent are useful antiarrhythmic agents. Pharmaceutical formulations containing such compounds are provided, as well as a method of treatment.

Abstract: Fluorenes bearing a 9-aminoalkyl substituent are useful antiarrhythmic agents. Pharmaceutical formulations containing such compounds are provided, as well as a method of treatment.

Abstract: 3-Substituted-5,6-diaryl-1,2,4-triazines active as antithrombotic agents when administered topically.

Abstract: Fluorenes bearing a 9-aminoalkyl substituent are useful antiarrhythmic agents. Pharmaceutical formulations containing such compounds are provided, as well as a method of treatment.

Abstract: Biphenylylalkylamines which have anti-arrhythmic activity have been prepared. Pharmaceutical formulations containing such compounds and a method of treating cardiac arrhythmias are provided.

Abstract: Cardiac arrhythmias are treated with 9-aminoalkyl-9-(hydroxy, cyano, or carbamoyl)-fluorenes.

Abstract: 5,6-Diaryl-1,2,4-triazines, topically-active anti-inflammatory agents, having the formula, ##STR1## wherein R is hydrogen or -(X).sub.n R.sub.1, in which X is either O or S, n is an integer which is either 0 or 1, and R.sub.1 is C.sub.1 -C.sub.8 alkyl, C.sub.7 -C.sub.8 aralkyl, C.sub.3 -C.sub.8 cycloalkyl, or C.sub.4 -C.sub.8 (cycloalkyl)alkyl; and R.sub.2 and R.sub.3 independently are C.sub.1 -C.sub.3 alkoxy or di(C.sub.1 -C.sub.3 alkyl)amino; with the proviso that when R.sub.2 and R.sub.3 both are methoxy, R cannot be H or methylthio; and the pharmaceutically-acceptable acid addition salts of basic members thereof.

Abstract: A method of controlling aquatic weeds which comprises adding to a body of water containing the aquatic weeds a substituted phenoxy(phenylthio)alkylamine in sufficient quantity to kill the weeds.

Abstract: 2,4-Diaminoquinazolines are employed as antithrombotic agents and have the following general formula: ##STR1## wherein R.sub.1 and R.sub.2 are monovalent groups independently selected from the group consisting ofA. ##STR2## wherein R.sub.4 and R.sub.5 independently are selected from the group consisting of hydrogen, alkyl, and cycloalkyl, with the proviso that both R.sub.4 and R.sub.5 cannot be cycloalkyl,B. ##STR3## wherein R.sub.6, R.sub.7, and R.sub.8 independently are selected from the group consisting of hydrogen and alkyl, and A is a divalent organic group having from two to about six carbon atoms such that the two nitrogen atoms are separated by at least two carbon atoms, andC. heterocyclic-amino, andR.sub.3 is a monovalent group selected from the group consisting of hydrogen, halogen, and alkyl.