Abstract: A computer-implemented method is provided to provide analysis of claim information. The system may receive claim data from a plurality of entities and, for one or more claim items in the received claim data, determine a format of the claim item. The system may convert the claim item from the determined format into a standard format. The system may receive a selection of one or more providers, and determine one or more claim items associated with the provider in the selection. The system may generate a user interface, the user interface comprising a visual representation of one or more attributes of the one or more claim items.

Abstract: A computer-implemented method is provided to provide analysis of claim information. The system may receive claim data from a plurality of entities and, for one or more claim items in the received claim data, determine a format of the claim item. The system may convert the claim item from the determined format into a standard format. The system may receive a selection of one or more providers, and determine one or more claim items associated with the provider in the selection. The system may generate a user interface, the user interface comprising a visual representation of one or more attributes of the one or more claim items.

Abstract: The invention relates to prostate specific membrane antigen antibodies (anti-PSMA) and anti-PSMA antibody drug conjugates. The invention also relates to methods and compositions for using anti-PSMA antibody drug conjugates in inhibiting, preventing or treating PSMA related diseases or cancers.

Abstract: The invention relates to prostate specific membrane antigen humanized antibodies (anti-PSMA) and anti-PSMA antibody drug conjugates. The invention also relates to methods and compositions for using anti-PSMA antibody drug conjugates in inhibiting, preventing or treating PSMA related diseases or cancers.

Abstract: A document review system is configured to quickly provide search results for large amounts of documents. Ontology templates are used to generate objects and links based on the documents. Users can view documents, and linked objects and object properties can be displayed. An index assisted search can be performed to determine the linked objects and object properties. A supplemental search can be performed on a second database that tracks modifications to the documents or objects. The modifications in the second database can be periodically written to the first database, and the index can be rebuilt. The user experience can be free of slow searches and slow index rebuilds.

Abstract: A computer-implemented method is provided to provide analysis of claim information. The system may receive claim data from a plurality of entities and, for one or more claim items in the received claim data, determine a format of the claim item. The system may convert the claim item from the determined format into a standard format. The system may receive a selection of one or more providers, and determine one or more claim items associated with the provider in the selection. The system may generate a user interface, the user interface comprising a visual representation of one or more attributes of the one or more claim items.

Abstract: A document review system is configured to quickly provide search results for large amounts of documents. Ontology templates are used to generate objects and links based on the documents. Users can view documents, and linked objects and object properties can be displayed. An index assisted search can be performed to determine the linked objects and object properties. A supplemental search can be performed on a second database that tracks modifications to the documents or objects. The modifications in the second database can be periodically written to the first database, and the index can be rebuilt. The user experience can be free of slow searches and slow index rebuilds.

Abstract: A computer-implemented method is provided to provide analysis of claim information. The system may receive claim data from a plurality of entities and, for one or more claim items in the received claim data, determine a format of the claim item. The system may convert the claim item from the determined format into a standard format. The system may receive a selection of one or more providers, and determine one or more claim items associated with the provider in the selection. The system may generate a user interface, the user interface comprising a visual representation of one or more attributes of the one or more claim items.

Abstract: A document review system is configured to quickly provide search results for large amounts of documents. Ontology templates are used to generate objects and links based on the documents. Users can view documents, and linked objects and object properties can be displayed. An index assisted search can be performed to determine the linked objects and object properties. A supplemental search can be performed on a second database that tracks modifications to the documents or objects. The modifications in the second database can be periodically written to the first database, and the index can be rebuilt. The user experience can be free of slow searches and slow index rebuilds.

Abstract: The invention relates to prostate specific membrane antigen humanized antibodies (anti-PSMA) and anti-PSMA antibody drug conjugates. The invention also relates to methods and compositions for using anti-PSMA antibody drug conjugates in inhibiting, preventing or treating PSMA related diseases or cancers.

Abstract: Multivalent binding peptides, including bi-specific binding peptides, having immunoglobulin effector function are provided, along with encoding nucleic acids, vectors and host cells as well as methods for making such peptides and methods for using such peptides to treat or prevent a variety of diseases, disorders or conditions, as well as to ameliorate at least one symptom associated with such a disease, disorder or condition.

Abstract: The present invention generally provides methods for B-cell reduction in an individual using CD37-specific binding molecules. In particular, the invention provides methods for B-cell reduction using CD37-specific binding molecules alone, or a combination of CD37-specific binding molecules and CD20-specific binding molecules, in some instances a synergistic combination. The invention further provides materials and methods for treatment of diseases involving aberrant B-cell activity. In addition; the invention provides humanized CD37-specific binding molecules.

Abstract: The present invention generally provides methods for B-cell reduction in an individual using CD37-specific binding molecules. In particular, the invention provides methods for B-cell reduction using CD37-specific binding molecules alone, or a combination of CD37-specific binding molecules and CD20-specific binding molecules, in some instances a synergistic combination. The invention further provides materials and methods for treatment of diseases involving aberrant B-cell activity. In addition, the invention provides humanized CD37-specific binding molecules.

Abstract: There is provided inter alia a process for stabilizing a eukaryotic cell line which expresses PylRS and tRNAPyl and which is suitable for incorporation of a gene encoding a target protein containing one or more non-natural amino acids encoded by a nonsense codon which comprises culturing said cell line under conditions in which the adverse effect of tRNAPyl expression on cell viability and/or cell growth is reduced or eliminated.

Abstract: The invention relates inter alia to a bivalent, bispecific construct comprising an anti-IL-6 antibody, or derivative thereof, and an anti-IL-23 antibody, or derivative thereof and its use in therapy. The invention also relates to useful anti-IL-6 antibodies and anti-IL-23 antibodies.

Abstract: The present invention generally provides methods for B-cell reduction in an individual using CD37-specific binding molecules. In particular, the invention provides methods for B-cell reduction using CD37-specific binding molecules alone, or a combination of CD37-specific binding molecules and CD20-specific binding molecules, in some instances a synergistic combination. The invention further provides materials and methods for treatment of diseases involving aberrant B-cell activity. In addition, the invention provides humanized CD37-specific binding molecules.

Abstract: Multivalent binding peptides, including bi-specific binding peptides, having immunoglobulin effector function are provided, along with encoding nucleic acids, vectors and host cells as well as methods for making such peptides and methods for using such peptides to treat or prevent a variety of diseases, disorders or conditions, as well as to ameliorate at least one symptom associated with such a disease, disorder or condition.

Abstract: There is provided inter alia a process for stabilizing a eukaryotic cell line which expresses PylRS and tRNAPyl and which is suitable for incorporation of a gene encoding a target protein containing one or more non-natural amino acids encoded by a nonsense codon which comprises culturing said cell line under conditions in which the adverse effect of tRNAPyl expression on cell viability and/or cell growth is reduced or eliminated.

Abstract: There is provided inter alia a process for stabilizing a eukaryotic cell line which expresses PylRS and tRNAPyl and which is suitable for incorporation of a gene encoding a target protein containing one or more non-natural amino acids encoded by a nonsense codon which comprises culturing said cell line under conditions in which the adverse effect of tRNAPyl expression on cell viability and/or cell growth is reduced or eliminated.

Abstract: The invention relates inter alia to a bivalent, bispecific construct comprising an anti-IL-6 antibody, or derivative thereof, and an anti-IL-23 antibody, or derivative thereof and its use in therapy. The invention also relates to useful anti-IL-6 and anti-IL-23 antibodies.