Patents by Inventor William Bryson

William Bryson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8981072
    Abstract: Antibody polypeptides that specifically bind human CD40L are provided. The antibody polypeptides do not activate platelets. The antibody polypeptides are useful in the treatment of diseases involving CD40L activation, such as graft-related diseases and autoimmune diseases. The antibody polypeptides may be domain antibodies (dAbs) comprising a single VH or VK domain. The half-life of the antibody polypeptides may be increased by modifying the antibody polypeptides to be dual specific reagents that can also bind human serum albumin (HSA) or another antigen.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: March 17, 2015
    Assignees: Bristol-Myers Squibb Company, Domantis Limited
    Inventors: Steven G. Nadler, James K. Tamura, Laura Price, Robert P. Rehfuss, Suzanne J. Suchard, Anish Suri, James William Bryson, Aaron Yamniuk, Steven Grant, Olga Ignatovich, Philip Drew
  • Publication number: 20150023976
    Abstract: Antibody polypeptides that specifically bind human CD40L are provided. The antibody polypeptides do not activate platelets. The antibody polypeptides are useful in the treatment of diseases involving CD40L activation, such as graft-related diseases and autoimmune diseases. The antibody polypeptides may be domain antibodies (dAbs) comprising a single VH or VK domain. The half-life of the antibody polypeptides may be increased by modifying the antibody polypeptides to be dual specific reagents that can also bind human serum albumin (HSA) or another antigen.
    Type: Application
    Filed: October 9, 2014
    Publication date: January 22, 2015
    Inventors: Steven G. NADLER, James K. TAMURA, Laura PRICE, Robert P. REHFUSS, Suzanne J. SUCHARD, Anish SURI, James William BRYSON, Aaron YAMNIUK, Steven GRANT, Olga IGNATOVICH, Philip DREW
  • Patent number: 8895010
    Abstract: Antibody polypeptides that specifically bind human CD40L are provided. The antibody polypeptides do not activate platelets. The antibody polypeptides are useful in the treatment of diseases involving CD40L activation, such as graft-related diseases and autoimmune diseases. The antibody polypeptides may be domain antibodies (dAbs) comprising a single VH or VK domain. The half-life of the antibody polypeptides may be increased by modifying the antibody polypeptides to be dual specific reagents that can also bind human serum albumin (HSA) or another antigen.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: November 25, 2014
    Assignees: Bristol-Myers Squibb Company, Domantis Limited
    Inventors: Steven G. Nadler, James K. Tamura, Laura Price, Robert P. Rehfuss, Suzanne J. Suchard, Anish Suri, James William Bryson, Aaron Yamniuk, Steven Grant, Olga Ignatovich, Philip Drew
  • Patent number: 8861217
    Abstract: This relates to systems and methods for providing one or more vias through a module of an electrical system. For example, in some embodiments, the module can include one or more passive elements and/or active of the electrical system around which a packaging has been plastic molded. The module can be stacked under another component of the electrical system. Vias can then be provided that extend through the module. The vias can include, for example, electrically conductive pathways. In this manner, the vias can provide electrical pathways for coupling the component stacked on top of the module to other entities of an electronic device including the electrical system. For example, the component can be coupled to other entities such as other components, other modules, printed circuit boards, other electrical systems, or to any other suitable entity.
    Type: Grant
    Filed: November 5, 2012
    Date of Patent: October 14, 2014
    Assignee: Apple Inc.
    Inventors: Gloria Lin, William Bryson Gardner, Jr., Joseph Fisher, Jr., Dennis Pyper, Amir Salehi
  • Publication number: 20140099707
    Abstract: Antibody polypeptides that specifically bind human CD40L are provided. The antibody polypeptides do not activate platelets. The antibody polypeptides are useful in the treatment of diseases involving CD40L activation, such as graft-related diseases and autoimmune diseases. The antibody polypeptides may be domain antibodies (dAbs) comprising a single VH or VK domain. The half-life of the antibody polypeptides may be increased by modifying the antibody polypeptides to be dual specific reagents that can also bind human serum albumin (HSA) or another antigen.
    Type: Application
    Filed: December 10, 2013
    Publication date: April 10, 2014
    Applicants: DOMANTIS LIMITED, BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Steven G. NADLER, James K. Tamura, Laura Price, Robert P. Rehfuss, Suzanne J. Suchard, Anish Suri, James William Bryson, Aaron Yamniuk, Steven Grant, Olga Ignatovich, Philip Drew
  • Patent number: 8384003
    Abstract: Systems and methods are provided for a display device including one or more methods for modifying the display brightness by automatically adapting to ambient lighting conditions.
    Type: Grant
    Filed: May 4, 2011
    Date of Patent: February 26, 2013
    Assignee: Apple Inc.
    Inventor: William Bryson Gardner, Jr.
  • Patent number: 7182320
    Abstract: A cable integrated guardrail system for highway guardrail. The rail of the system contains at least one cut section placed longitudinally along the panel, and of sufficient dimension as to allow interaction with a cable. Said cut sections also act to reduce longitudinal resistance and safely stop axially impacting vehicles. A cable, which is of sufficient length to extend longitudinally along the entire system, prevents tearing of the rail during lateral impacts and aids in safely redirecting the vehicle away from a hazard.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: February 27, 2007
    Assignee: Bryson Products, Inc.
    Inventors: Chad Garrett Heimbecker, William Bryson, William Atwood
  • Patent number: 7058864
    Abstract: Systems, methods, software products test a memory cache of a processor that includes a test engine (e.g., a BISTE). High level test source code is formulated to use routines in API source code that, when compiled into machine test code, interfaces with the test engine. The machine test code is executed with the processor to test the memory cache to detect one or more faulty memory blocks in the memory cache. If any of the faulty memory blocks are detected, the test engine is instructed, through the machine test code, to set one or more bits in registers to functionally replace the faulty memory blocks with redundant blocks of the memory cache.
    Type: Grant
    Filed: May 21, 2003
    Date of Patent: June 6, 2006
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: William Bryson McHardy, Raymond Paul Gratias, Kevin Miller, Brian Nugent
  • Publication number: 20050077507
    Abstract: A cable integrated guardrail system for highway guardrail. The rail of the system contains at least one cut section placed longitudinally along the panel, and of sufficient dimension as to allow interaction with a cable. Said cut sections also act to reduce longitudinal resistance and safely stop axially impacting vehicles. A cable, which is of sufficient length to extend longitudinally along the entire system, prevents tearing of the rail during lateral impacts and aids in safely redirecting the vehicle away from a hazard.
    Type: Application
    Filed: December 3, 2004
    Publication date: April 14, 2005
    Inventors: Chad Heimbecker, William Bryson, William Atwood
  • Publication number: 20040140460
    Abstract: A cable integrated guardrail system for highway guardrail. The rail of the system contains at least one cut section placed longitudinally along the panel, and of sufficient dimension as to allow interaction with a cable. Said cut sections also act to reduce longitudinal resistance and safely stop axially impacting vehicles. A cable, which is of sufficient length to extend longitudinally along the entire system, prevents tearing of the rail during lateral impacts and aids in safely redirecting the vehicle away from a hazard.
    Type: Application
    Filed: December 20, 2002
    Publication date: July 22, 2004
    Inventors: Chad Garrett Heimbecker, William Bryson, William Atwood
  • Publication number: 20040143531
    Abstract: Techniques are disclosed for automatically synthesizing information from a plurality of computer-readable integrated circuit package models. In one embodiment, each of the plurality of package models contains information descriptive of a distinct package. Such information may include, for example, intra-package path lengths and/or propagation delays of signal nets in the modeled packages. Techniques are disclosed for automatically synthesizing such information to produce, for example, aggregate path lengths and/or propagation delays of the signal nets across all of the modeled packages. Such synthesis may be performed even when the package models use mutually inconsistent signal net naming conventions and the modeled packages are composed of different materials. Techniques are also disclosed for providing information to the package designer to assist the package designer in improving the design of the package models.
    Type: Application
    Filed: January 9, 2004
    Publication date: July 22, 2004
    Inventors: Mark D. Frank, William Bryson McHardy, Peter Shaw Moldauer
  • Patent number: 6711730
    Abstract: Techniques are disclosed for automatically synthesizing information from a plurality of computer-readable integrated circuit package models. In one embodiment, each of the plurality of package models contains information descriptive of a distinct package. Such information may include, for example, intra-package path lengths and/or propagation delays of signal nets in the modeled packages. Techniques are disclosed for automatically synthesizing such information to produce, for example, aggregate path lengths and/or propagation delays of the signal nets across all of the modeled packages. Such synthesis may be performed even when the package models use mutually inconsistent signal net naming conventions and the modeled packages are composed of different materials. Techniques are also disclosed for providing information to the package designer to assist the package designer in improving the design of the package models.
    Type: Grant
    Filed: May 13, 2002
    Date of Patent: March 23, 2004
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Mark D. Frank, William Bryson McHardy, Peter Shaw Moldauer
  • Publication number: 20030212980
    Abstract: Techniques are disclosed for automatically synthesizing information from a plurality of computer-readable integrated circuit package models. In one embodiment, each of the plurality of package models contains information descriptive of a distinct package. Such information may include, for example, intra-package path lengths and/or propagation delays of signal nets in the modeled packages. Techniques are disclosed for automatically synthesizing such information to produce, for example, aggregate path lengths and/or propagation delays of the signal nets across all of the modeled packages. Such synthesis may be performed even when the package models use mutually inconsistent signal net naming conventions and the modeled packages are composed of different materials. Techniques are also disclosed for providing information to the package designer to assist the package designer in improving the design of the package models.
    Type: Application
    Filed: May 13, 2002
    Publication date: November 13, 2003
    Inventors: Mark D. Frank, William Bryson McHardy, Peter Shaw Moldauer
  • Patent number: 6454488
    Abstract: An energy absorbing system comprising a plurality of break-away post elements sequentially spaced to be sheared off by impact of a vehicle. Each post element individually absorbs and decelerates the impacting vehicle at a pre-determined rate that in multiple successive impacts slows the vehicle to a stop before the barrier or to an acceptable speed within the design requirements for impact with a barrier.
    Type: Grant
    Filed: February 2, 2000
    Date of Patent: September 24, 2002
    Inventors: David Lewis, Sr., David Hubbell, William Bryson, William Atwood