Abstract: A leaflet resection device includes a first jaw, a second jaw pivotably connected to the first jaw, a first linkage assembly coupled to the first jaw, and a second linkage assembly coupled to the second jaw. The second linkage assembly includes a first resection blade and a second resection blade that are configured to cut a leaflet of a native heart valve or a previously implanted valve prosthesis along a curved path when the first and second linkage assemblies are actuated.

Abstract: A catheter includes a handle with torqueing and steering mechanisms. The torqueing mechanism includes a rotatable nosecone and a bearing coupled to the nosecone to be rotatable therewith. The bearing is concentrically disposed over a shaft of the catheter. The steering mechanism includes a rack coupled to the bearing to be slideable therewith and a pull wire having a proximal end attached to the bearing and a distal end attached to a distal portion of the shaft. Rotation of the nosecone causes an entire length of the shaft to rotate and axial movement of the rack tensions the pull wire to bend the distal portion of the shaft. A valve relief component is slidingly disposed over the shaft and is configured to dock onto the handle when not in use.

Abstract: Aspects of this disclosure relate to a computing cabinet for a computing system and to computing systems with one or more computing cabinets. The computing cabinet can include a power plane for power conversion, a compute plane, and a host plane. Computing cabinets disclosed herein can be modular and scalable. The computing cabinet can be configured such that components thereof can be hot swapped.

Abstract: Aspects of this disclosure relate to power delivery to chips in an array. An array of power conversion paths can be positioned vertically relative to the chips of the array. A power conversion path can convert a high voltage, low current signal to a low voltage, high current. The power conversion path can include a first power conversion stage and a second power conversion stage. The power conversion path can be implemented in a power supply module, for example.

Abstract: A leaflet resection device includes a first jaw, a second jaw pivotably connected to the first jaw, a first linkage assembly coupled to the first jaw, and a second linkage assembly coupled to the second jaw. The second linkage assembly includes a first resection blade and a second resection blade that are configured to cut a leaflet of a native heart valve or a previously implanted valve prosthesis along a curved path when the first and second linkage assemblies are actuated.

Abstract: Systems and methods of for vertical power and clock delivery are disclosed. In some embodiments, a computing system can include an array of chips comprising a chip and a power delivery module configured to provide a power supply voltage and one or more clock signals to the chip, the power delivery module being positioned vertically relative to the chip, and the chip configured to vertically receive the one or more clock signals from the power delivery module.

Abstract: An optical device includes a first layer having a first surface and a first set of surface coatings. The optical device includes a second layer having a second surface and an opposing third surface, and a second set of surface coatings. A first surface coating in the second set of surface coatings is bonded to the third surface. An outer surface coating in the first set of surface coatings is covalently bonded to the second surface of the second layer through a plurality of covalent interactions of the form X—O—Y, thereby attaching the first layer and the second layer to each other. Each X is an atom of the outer surface coating of the first set of surface coatings, O is an oxygen atom, and each Y is an atom of the second layer.

Abstract: A method that includes receiving information system tickets, generating for each information system ticket a first state of data to capture an original state of one or more end-user operational data, generating for each information system ticket a second state of data to capture a changed state of the one or more end-user operational data, storing the first state and the second state in a database, and mining the database for changes in end-user operational data between the first state and the second state to generate patterns of changes. The patterns of changes are clustered into a number of clusters with each cluster representing a different ticketing issue.

Abstract: A catheter includes a handle with torqueing and steering mechanisms. The torqueing mechanism includes a rotatable nosecone and a bearing coupled to the nosecone to be rotatable therewith. The bearing is concentrically disposed over a shaft of the catheter. The steering mechanism includes a rack coupled to the bearing to be slideable therewith and a pull wire having a proximal end attached to the bearing and a distal end attached to a distal portion of the shaft. Rotation of the nosecone causes an entire length of the shaft to rotate and axial movement of the rack tensions the pull wire to bend the distal portion of the shaft. A valve relief component is slidingly disposed over the shaft and is configured to dock onto the handle when not in use.

Abstract: A catheter includes a handle with torqueing and steering mechanisms. The torqueing mechanism includes a rotatable nosecone and a bearing coupled to the nosecone to be rotatable therewith. The bearing is concentrically disposed over a shaft of the catheter. The steering mechanism includes a rack coupled to the bearing to be slideable therewith and a pull wire having a proximal end attached to the bearing and a distal end attached to a distal portion of the shaft. Rotation of the nosecone causes an entire length of the shaft to rotate and axial movement of the rack tensions the pull wire to bend the distal portion of the shaft. A valve relief component is slidingly disposed over the shaft and is configured to dock onto the handle when not in use.

Abstract: In some examples, a neuromodulation catheter includes a neuromodulation element convertible between a low-profile delivery state and a radially expanded deployed state, the neuromodulation element including: an elongated structure configured to have a substantially linear shape defining a longitudinal axis when the neuromodulation element is in the low-profile delivery state, and further configured to have a coiled shape defining a coiled outer surface when the neuromodulation element is in the radially expanded deployed state; one or more electrodes spaced longitudinally apart along the longitudinal axis of the elongated structure; and one or more wires coupled to respective electrodes of one or more electrodes at respective coupling points, wherein the coupling points are arranged such that, when the neuromodulation element is in the deployed state, the coupling points are oriented along the coiled outer surface of the elongated structure.

Abstract: Embodiments herein are generally directed to a system and process for manufacturing temperature measurement devices for use in semiconductor and display manufacturing. A bifurcated thermocouple substrate is provided and includes a primary substrate with a substrate aperture, a secondary substrate disposed within the substrate aperture, and a thermocouple disposed within a thermocouple aperture of the secondary substrate.

Abstract: A leaflet resection device includes a first jaw, a second jaw pivotably connected to the first jaw, a first linkage assembly coupled to the first jaw, and a second linkage assembly coupled to the second jaw. The second linkage assembly includes a first resection blade and a second resection blade that are configured to cut a leaflet of a native heart valve or a previously implanted valve prosthesis along a curved path when the first and second linkage assemblies are actuated.

Abstract: Balloon catheters for delivery of prosthetic hear valves are provided. The balloon catheters are configured to deploy a prosthetic heart valve through inflation. The balloon catheters are further configured with one or more retention bumpers to reduce or prevent migration of the prosthetic heart valve during delivery. Balloon catheters described herein are configured with substantially incompressible retention bumpers that promote longitudinal inflation fluid flow.

Abstract: Balloon catheters for delivery of prosthetic hear valves are provided. The balloon catheters are configured to deploy a prosthetic heart valve through inflation. The balloon catheters are further configured with one or more retention bumpers to reduce or prevent migration of the prosthetic heart valve during delivery. Balloon catheters described herein are configured with substantially incompressible retention bumpers that promote longitudinal inflation fluid flow.

Abstract: A valve leaflet resection device includes a catheter (110), an electrode assembly (140) slidably disposed within the catheter and deployable from the catheter and configured to remove a portion of a leaflet of a heart valve, a leaflet retainer (130) slidably disposed within the catheter and deployable from the catheter, the leaflet retainer configured to grasp a leaflet of a heart valve, and a capture basket (120) configured to capture a resected portion of the leaflet of the heart valve upon retraction of the leaflet retainer.

Abstract: Aspects of this disclosure relate to power delivery to chips in an array. An array of power conversion paths can be positioned vertically relative to the chips of the array. A power conversion path can convert a high voltage, low current signal to a low voltage, high current. The power conversion path can include a first power conversion stage and a second power conversion stage. The power conversion path can be implemented in a power supply module, for example.

Abstract: A catheter may include an elongate body comprising a proximal portion and a distal portion, and a plurality of electrodes carried by the distal portion. The distal portion of the catheter may be configured to transform from a low-profile delivery state to a radially expanded deployed state in which at least some electrodes of ‘the plurality of electrodes are deployed at different circumferential positions of the radially expanded deployed slate. A ratio of a deployed electrode length to a diameter of the distal portion of the catheter in the radially expanded deployed state may be less than or equal to about 2.0. The deployed electrode length is a distance between, in the radially expanded deployed, stole, a proximal-most point of a proximal-most electrode of the plurality of electrodes and a distal-most point of a distal-most electrode of the plurality of electrodes.

Abstract: Systems and methods of for vertical power and clock delivery are disclosed. In some embodiments, a computing system can include an array of chips comprising a chip and a power delivery module configured to provide a power supply voltage and one or more clock signals to the chip, the power delivery module being positioned vertically relative to the chip, and the chip configured to vertically receive the one or more clock signals from the power delivery module.

Abstract: The systems, methods, and devices disclosed herein relate to a multi-layer structures arranged in a vertically orientation. In some embodiments, a computing assembly can include a first cooling system, a first electronics layer, a second cooling system, and a second electronics layer. The first cooling system can be disposed on top of and can be in thermal communication with the first electronics layer. The first electronics layer array includes an array of integrated circuit dies that are in electronic communication with each other in a plane that is orthogonal to power delivery. The first electronics layer can be disposed on top of and can be in thermal communication with the second cooling system, and the second cooling system can be disposed on top of and can be in thermal communication with the second electronics layer. The second electronics layer includes an array of power delivery modules. In some embodiments, at least one layer can use system on wafer packaging.