Patents by Inventor William D. Carlson

William D. Carlson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for producing morphogen analogs
    Publication number: 20020028453
    Abstract: The invention disclosed herein provides methods and compositions for the computer-assisted design of morphogen analogs. Practice of the invention is enabled by the use of at least a portion of the atomic co-ordinates defining the three-dimensional structure of human osteogenic protein-1 (hOP-1) as a starting point in the design of the morphogen analogs. In addition, the invention provides methods for producing morphogen analogs of interest, and methods for testing whether the resulting analogs mimic or agonize human OP-1-like biological activity. The invention also provides a family of morphogen analogs produced by such methods.
    Type: Application
    Filed: February 22, 2001
    Publication date: March 7, 2002
    Inventors: Peter C. Keck, Diana L. Griffith, William D. Carlson, David C. Rueger, Kuber T. Sampath
  • Computer system and methods for producing morphogen analogs of human OP-1
    Patent number: 6273598
    Abstract: The invention disclosed herein provides methods and compositions for the computer-assisted design of morphogen analogs. Practice of the invention is enabled by the use of at least a portion of the atomic co-ordinates defining the three-dimensional structure of human osteogenic protein-1 (hOP-1) as a starting point in the design of the morphogen analogs. In addition, the invention provides methods for producing morphogen analogs of interest, and methods for testing whether the resulting analogs mimic or agonize human OP-1-like biological activity. The invention also provides a family of morphogen analogs produced by such methods.
    Type: Grant
    Filed: January 22, 1997
    Date of Patent: August 14, 2001
    Assignee: Creative BioMolecules, Inc.
    Inventors: Peter C. Keck, Diana L. Griffith, William D. Carlson, David C. Rueger, Kuber T. Sampath