Patents by Inventor William G. Weisburg

William G. Weisburg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation of nucleic acids
    Patent number: 9845491
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: December 19, 2017
    Assignee: Exact Sciences Corporation
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
  • Isolation of nucleic acids
    Patent number: 9631228
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: April 25, 2017
    Assignee: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
  • ISOLATION OF NUCLEIC ACIDS
    Publication number: 20160130635
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Application
    Filed: November 12, 2015
    Publication date: May 12, 2016
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
  • Isolation of nucleic acids
    Patent number: 9169511
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: October 27, 2015
    Assignee: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
  • Isolation of nucleic acids
    Patent number: 9163278
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: October 20, 2015
    Assignee: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
  • ISOLATION OF NUCLEIC ACIDS
    Publication number: 20150284770
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Application
    Filed: May 15, 2015
    Publication date: October 8, 2015
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
  • Isolation of nucleic acids
    Patent number: 9000146
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting multiple DNA targets from a human stool sample with, for example, methods employing spin filtration techniques.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: April 7, 2015
    Assignee: Exact Sciences Corporation
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II
  • MARKER PANEL FOR DETECTING CANCER
    Publication number: 20150072866
    Abstract: Provided herein is technology relating to detecting cancer and particularly, but not exclusively, to methods for detecting colorectal cancer by evaluating multiple markers in paired plasma and stool samples. In particular, the technology relates to CRC screening by assaying plasma for methylated Septin 9 and assaying stool DNA for methylated vimentin, NDRG4, BMP3, and/or TFPI2.
    Type: Application
    Filed: March 20, 2013
    Publication date: March 12, 2015
    Inventors: William G. Weisburg, Graham P. Lidgard, David A. Ahlquist, William R. Taylor
  • ISOLATION OF NUCLEIC ACIDS
    Publication number: 20140194607
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Application
    Filed: December 31, 2013
    Publication date: July 10, 2014
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
  • ISOLATION OF NUCLEIC ACIDS
    Publication number: 20140194608
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Application
    Filed: December 31, 2013
    Publication date: July 10, 2014
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
  • ISOLATION OF NUCLEIC ACIDS
    Publication number: 20120288868
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Application
    Filed: May 11, 2012
    Publication date: November 15, 2012
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II
  • Assay and compositions for detection of nucleic acid
    Patent number: 8293885
    Abstract: The invention includes compositions and methods of detection of Bacillus anthracis that use oligonucleotide probes specific for genetic material contained in the pXO1 and pXO2 plasmids in nucleic acid hybridization reactions. Embodiments of the method may include additional probes specific for other gene sequences to distinguish B. anthracis from other bacterial species present in a sample or to provide an indication that the assay was performed properly even when no Bacillus sequence is detected.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: October 23, 2012
    Assignee: Gen-Probe Incorporated
    Inventors: Sylvia A. Norman, Jennifer J. Bungo, James J. Hogan, William G. Weisburg
  • Assay and Compositions for Detection of Bacillus Anthracis Nucleic Acid
    Publication number: 20120171669
    Abstract: The invention includes compositions and methods of detection of Bacillus anthracis that use oligonucleotide probes specific for genetic material contained in the pXO1 and pXO2 plasmids in nucleic acid hybridization reactions. Embodiments of the method may include additional probes specific for other gene sequences to distinguish B. anthracis from other bacterial species present in a sample or to provide an indication that the assay was performed properly even when no Bacillus sequence is detected.
    Type: Application
    Filed: October 31, 2007
    Publication date: July 5, 2012
    Applicant: GEN-PROBE INCORPORATED
    Inventors: Sylvia A. Norman, Jennifer J. Bungo, James J. Hogan, William G. Weisburg
  • Compositions and methods for detecting the presence of in a test sample
    Patent number: 8105779
    Abstract: The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Cryptosporidium organisms, and Cryptosporidium parvum organisms in particular, which are useful for determining the presence of Cryptosporidium organisms in a test sample. The oligonucleotides of the present invention include hybridization assay probes, helper probes and amplification primers. The present invention further describes a novel method for obtaining purified ribonucleic acid from viable oocysts.
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: January 31, 2012
    Inventors: Melissa M. Cunningham, Paul D. Stull, William G. Weisburg
  • Compositions and Methods For Detecting The Presence Of Cryptosporidium Parvum In A Test Sample
    Publication number: 20110269133
    Abstract: The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Cryptosporidium organisms, and Cryptosporidium parvum organisms in particular, which are useful for determining the presence of Cryptosporidium organisms in a test sample. The oligonucleotides of the present invention include hybridization assay probes, helper probes and amplification primers. The present invention further describes a novel method for obtaining purified ribonucleic acid from viable oocysts.
    Type: Application
    Filed: July 14, 2011
    Publication date: November 3, 2011
    Applicant: GEN-PROBE INCORPORATED
    Inventors: Melissa M. CUNNINGHAM, Paul D. STULL, William G. WEISBURG
  • Compositions and methods for detecting the presence of cryptosporidium organisms in a test sample
    Patent number: 8008017
    Abstract: The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Cryptosporidium organisms, and Cryptosporidium parvum organisms in particular, which are useful for determining the presence of Cryptosporidium organisms in a test sample. The oligonucleotides of the present invention include hybridization assay probes, helper probes and amplification primers. The present invention further describes a novel method for obtaining purified ribonucleic acid from viable oocysts.
    Type: Grant
    Filed: September 8, 2009
    Date of Patent: August 30, 2011
    Assignee: Gen-Probe Incorporated
    Inventors: Melissa M. Cunningham, Paul D. Stull, William G. Weisburg
  • Compositions and Methods For Detecting The Presence Of Cryptosporidium Organisms In A Test Sample
    Publication number: 20100003693
    Abstract: The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Cryptosporidium organisms, and Cryptosporidium parvum organisms in particular, which are useful for determining the presence of Cryptosporidium organisms in a test sample. The oligonucleotides of the present invention include hybridization assay probes, helper probes and amplification primers. The present invention further describes a novel method for obtaining purified ribonucleic acid from viable oocysts.
    Type: Application
    Filed: September 8, 2009
    Publication date: January 7, 2010
    Applicant: GEN-PROBE INCORPORATED
    Inventors: Melissa M. CUNNINGHAM, Paul D. STULL, William G. WEISBURG
  • Oligonucleotides for amplifying -derived nucleic acid
    Patent number: 7632934
    Abstract: Oligonucleotides useful for determining the presence of Trichomonas vaginalis in a test sample. The oligonucleotides may be incorporated into detection probes, helper probes, capture probes and amplification oligonucleotides, and used in various combinations thereof.
    Type: Grant
    Filed: May 15, 2008
    Date of Patent: December 15, 2009
    Assignee: Gen-Probe Incorporated
    Inventors: William G. Weisburg, Jennifer J. Bungo
  • Method for obtaining purified RNA from viable oocysts
    Patent number: 7585631
    Abstract: The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Crytosporidium organisms, and Crytosporidium parvum organisms in particular, which are useful for determining the presence of Cryptosporidium organisms in a test sample. The oligonucleotides of the present invention include hybridization assay probes, helper probes and amplification primers. The present invention further describes a novel method for obtaining purified ribonucleic acid from viable oocysts.
    Type: Grant
    Filed: July 25, 2006
    Date of Patent: September 8, 2009
    Assignee: Gen-Probe Incorporated
    Inventors: Melissa M. Cunningham, Paul D. Stull, William G. Weisburg
  • Assay and compositions for detection of nucleic acid
    Patent number: 7494774
    Abstract: The invention includes compositions and methods of detection of Bacillus anthracis that use oligonucleotide probes specific for genetic material contained in the pXO1 and pXO2 plasmids in nucleic acid hybridization reactions. Embodiments of the method may include additional probes specific for other gene sequences to distinguish B. anthracis from other bacterial species present in a sample or to provide an indication that the assay was performed properly even when no Bacillus sequence is detected.
    Type: Grant
    Filed: November 12, 2003
    Date of Patent: February 24, 2009
    Assignee: Gen-Probe Incorporated
    Inventors: Sylvia Ann Norman, Jennifer Jill Bungo, James J. Hogan, William G. Weisburg