Abstract: Compounds of the formula: ##STR1## wherein R.sub.1 is C.sub.2- C.sub.12 linear or branched unsubstituted alkyl; C.sub.1- C.sub.12 linear or branched substituted alkyl; C.sub.2 -C.sub.12 linear or branched monoalkenyl; C.sub.2 -C.sub.12 linear or branched alkynyl; C.sub.7 -C.sub.20 aralkyl, wherein the alkyl chain is linear or branched C.sub.1- C.sub.8 and the aryl moiety is C.sub.6- C.sub.12 ; C.sub.4- C.sub.10 cycloalkylalkyl; C.sub.3- C.sub.7 cycloalkyl; wherein these values for R.sub.1, other than C.sub.2- C.sub.12 linear or branched unsubstituted alkyl, can be substituted by one or more of C.sub.1 -C.sub.4 alkoxy, C.sub.3- C.sub.6 cycloalkyloxy, C.sub.3- C.sub.6 cycloalkylthio, C.sub.6- C.sub.12 aryloxy, C.sub.1- C.sub.4 alkylthio, C.sub.6- C.sub.12 arylthio, C.sub.7- C.sub.10 aralkyloxy, C.sub.7- C.sub.16 aralkyl-thio; and R.sub.5 is H or C.sub.1- C.sub.12 linear or branched alkyl; C.sub.2- C.sub.12 linear or branched monoalkenyl; C.sub.7- C.sub.

Abstract: New 3-(1-aminoalkylphosphinyl)-(2-substituted)propionic acids are described which display antibacterial activity and potentiate carbapenem antibiotics.

Abstract: New 3-(1-aminoalkylphosphinyl)-(2-substituted)propionic acids are described which display antibacterial activity and potentiate carbapenem antibiotics.

Abstract: Peptides of the formula: ##STR1## which comprise novel elements replacing the Phe(8)-His(9) sequence in renin-inhibitory peptides based on substrate analogy, which inhibit the substrate-cleaving action of renin and have improved bioavailability; compositions containing these renin-inhibitory peptides, optionally with other antihypertensive agents; and methods of treating hypertension or congestive heart failure or of establishing renin as a causative factor in these problems which employ the novel peptides.

Abstract: Peptides of the formula: ##STR1## which comprise novel elements replacing the Phe(8)-His(9) sequence in renin-inhibitory peptides based on substrate analogy, which inhibit the substrate-cleaving action of renin and have improved bioavailability; compositions containing these renin-inhibitory peptides, optionally with other antihypertensive agents; and methods of treating hypertension or congestive heart failure or of establishing renin as a causative factor in these problems which employ the novel peptides.

Abstract: Dipeptide mimics which contain phosphorus and their pharmaceutical use and preparation are disclosed. The compounds have dehydropeptidase (DHP) enzyme inhibitor activity.

Abstract: Benzofused lactams of the formula: ##STR1## and their use as angiotensin converting enzyme inhibitors and antihypertensive agents are disclosed.

Abstract: Peptides of the formula: ##STR1## which comprise novel elements replacing the Phe(8)-His(9) sequence in renin-inhibitory peptides based on substrate analogy, which inhibit the substrate-cleaving action of renin and have improved bioavailability; compositions containing these renin-inhibitory peptides, optionally with other antihypertensive agents; and methods of treating hypertension or congestive heart failure or of establishing renin as a causative factor in these problems which employ the novel peptides.

Abstract: This invention relates to lactams, bicyclic lactams and related compounds which are useful as cholecystokinin antagonists.

Abstract: There are disclosed bicyclic lactams and derivatives thereof which are useful as converting enzyme inhibitors and as antihypertensives.

Abstract: New 3-(1-aminoalkylphosphinyl)-(2-substituted)propionic acids are described which display antibacterial activity and potentiate carbapenem antibiotics.

Abstract: Benzofused lactams and pharmaceutically-acceptable salts thereof which are useful as cholecystokinin antagonists.

Abstract: Benzofused lactams and their use as antagonists of cholecystokinin are disclosed.

Abstract: Substituted lactams and related compounds and methods for their preparation are disclosed. These compounds are useful as angiotensin converting enzyme inhibitors and as antihypertensives.

Abstract: Compounds of the formula: ##STR1## and pharmaceutically acceptable salts thereof are inhibitors of angiotensin I converting enzyme and are useful as antihypertensive agents and are also useful as cholecystokinin antagonists.

Abstract: Compounds of the formula: ##STR1## where R.sup.3 is ##STR2## where n is 1-3 and the R.sup.a 's and R.sup.b 's are independently hydrogen or loweralkyl; and pharmaceutically acceptable salts thereof; are inhibitors or angiotensin I converting enzyme useful as antihypertensive agents.

Abstract: A ball cage retainer of the type including a pair of coextensive strips having annular pocket portions defined by truncated angular flanges to define ball retaining pockets for rotatably retaining balls between the strips with the strips spot welded together and a method and apparatus for assembling such a ball cage. The ball cage is utilized in a conduit of a motion transmitting remote control assembly for facilitating the movement of a motion transmitting core element within the conduit. The cage is assembled by indexing a pair of metal ribbon-like strips successively through a plurality of stations by two sets of fixed and movable clamping assemblies. The pocket portions, and alignment notches adjacent the pocket portions, are simultaneously formed in each of the strips at a first station as the strips pass through the first station in parallel relationship to one another. One of the strips passes through a second station and balls are placed in each of the pocket portions of that strip.

Abstract: A ball cage retainer of the type including a pair of coextensive strips having annular pocket portions defined by truncated angular flanges to define ball retaining pockets for rotatably retaining balls between the strips with the strips spot welded together and a method and apparatus for assembling such a ball cage. The ball cage is utilized in a conduit of a motion transmitting remote control assembly for facilitating the movement of a motion transmitting core element within the conduit. The cage is assembled by indexing a pair of metal ribbon-like strips successively through a plurality of stations by two sets of fixed and movable clamping assemblies. The pocket portions, and alignment notches adjacent the pocket portions, are simultaneously formed in each of the strips at a first station as the strips pass through the first station in parallel relationship to one another. One of the strips passes through a second station and balls are placed in each of the pocket portions of that strip.