Patents by Inventor William Holmes
William Holmes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 12194188Abstract: A rack for sanitizing or cleaning medical or personal protective equipment is claimed herein. The rack has at least two stringers that run the length of the rack. The rack has at least two vertical grates that are spaced apart from each other along the stringers. The spacing between the grates will be sufficient such that a standard respiratory mask (e.g. N95) may be placed between two adjacent grates and be held in a vertical orientation.Type: GrantFiled: April 1, 2021Date of Patent: January 14, 2025Assignee: University of Louisiana at LafayetteInventors: Mark E. Zappi, William Holmes, Andrei Chistoserdov, Wayne Sharp, Alex Zappi, Rafael Hernandez, William Chirdon, Don Begneaud, Thomas Broussard
-
Publication number: 20240349668Abstract: An aquaponic system comprises a growing enclosure having a roof and first second transparent parallel perimeter walls. A controller may energize a motor-driven spindle above and between the perimeter walls to raise or lower wound sheets of reflective material to control sunlight admitted into the enclosure. A fish tank within the enclosure contains fluid and fish and a drain outlet leading to a sludge separator. Sludge is processed through a series of biofilter tanks to produce a nutrient fluid irrigated onto plants growing in bed tubes arrayed in cylindrical grow towers. Tubs beneath the grow towers contain nutrient soil and other organisms. Several closed loops of pumped fluid flows circulate nutrient fluids among the fish tank, sludge tank, biofilter tanks, and irrigation lines for the grow towers. Flow restrictors balance these flow loops. Vortex oxygenators at points along the flow loops mix air into the circulating nutrient fluids.Type: ApplicationFiled: April 19, 2024Publication date: October 24, 2024Inventor: William Holm
-
Publication number: 20240315913Abstract: A method for treatment of a headache disorder in a human subject including introducing a stimulation member, arranged in a non-expanded state, into a first nasal cavity of the human subject, expanding the stimulation member so that it abuts against tissue of the first nasal cavity at a first pressure in a range between 80 and 100 mbar, and imparting vibrations to the tissue of the first nasal cavity at a first frequency in a range between 70 and 100 Hz for a first duration.Type: ApplicationFiled: May 31, 2024Publication date: September 26, 2024Applicant: CHORDATE MEDICAL ABInventors: Jan-Erik JUTO, William HOLM, Fredrik JUTO
-
Publication number: 20240307436Abstract: The present invention provides improved methods for producing retinal pigmented epithelial (RPE) cells from human embryonic stem cells, human induced pluripotent stem (iPS), human adult stem cells, human hematopoietic stem cells, human fetal stem cells, human mesenchymal stem cells, human postpartum stem cells, human multipotent stem cells, or human embryonic germ cells. The RPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The RPE cells described herein are useful for treating retinal degenerative conditions including retinal detachment and macular degeneration.Type: ApplicationFiled: November 8, 2023Publication date: September 19, 2024Applicant: Astellas Institute for Regenerative MedicineInventors: Christopher Malcuit, Linda Lemieux, William Holmes, Pedro Huertas, Lucy Vilner
-
Patent number: 12042465Abstract: A method for treatment of a headache disorder in a human subject, including selecting at least one treatment area in the nasal cavity of the human subject, said treatment area being selected from a posterior part of the nasal cavity or an anterior part of the nasal cavity, providing a device including a stimulation member arranged for vibration stimulation of the selected treatment area, and at least one expansion member provided with a channel having a plurality of openings arranged for fluid communication with the stimulation member, introducing the stimulation member into a nasal cavity of the human subject, expanding the stimulation member to a volume such that the stimulation member abuts against the tissue to exert a pressure on tissue of the selected treatment area and bringing the stimulation member to vibrate in the nasal cavity to impart vibrations to the selected treatment area, wherein the vibrations are imparted to a posterior part of the nasal cavity, to an anterior part of the nasal cavity, seqType: GrantFiled: September 12, 2022Date of Patent: July 23, 2024Assignee: CHORDATE MEDICAL ABInventors: Jan-Erik Juto, William Holm, Fredrik Juto
-
Publication number: 20240148784Abstract: The present invention provides improved methods for producing retinal pigmented epithelial (RPE) cells from human embryonic stem cells, human induced pluripotent stem (iPS), human adult stem cells, human hematopoietic stem cells, human fetal stem cells, human mesenchymal stem cells, human postpartum stem cells, human multipotent stem cells, or human embryonic germ cells. The RPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The RPE cells described herein are useful for treating retinal degenerative conditions including retinal detachment and macular degeneration.Type: ApplicationFiled: November 8, 2023Publication date: May 9, 2024Applicant: Astellas Institute for Regenerative MediceInventors: Christopher Malcuit, Linda Lemieux, William Holmes, Pedro Huertas, Lucy Vilnr
-
Patent number: 11850261Abstract: The present invention provides improved methods for producing retinal pigmented epithelial (RPE) cells from human embryonic stem cells, human induced pluripotent stem (iPS), human adult stem cells, human hematopoietic stem cells, human fetal stem cells, human mesenchymal stem cells, human postpartum stem cells, human multipotent stem cells, or human embryonic germ cells. The RPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The RPE cells described herein are useful for treating retinal degenerative conditions including retinal detachment and macular degeneration.Type: GrantFiled: October 9, 2019Date of Patent: December 26, 2023Assignee: Astellas Institute for Regenerative MedicineInventors: Christopher Malcuit, Linda Lemieux, William Holmes, Pedro Huertas, Lucy Vilner
-
Publication number: 20230093562Abstract: This invention is a novel method to thermally process wet WWTP sludges, including biosolids, so that they can be classified. Wet biosolids or other WWTP sludges are passed through the heating zones of one or more solar thermal systems so that the sludges are heated to a target temperature to meet the requirements for U.S. Environmental Protection Agency classification. Various catalysts are provided before the sludges enter the heating zone and within the heating zone to optimize the treatment of the sludges.Type: ApplicationFiled: September 16, 2022Publication date: March 23, 2023Applicant: University of Louisiana at LafayetteInventors: Mark E. ZAPPI, Terence Chambers, Wayne Sharp, Rafaei Hernandez, Daniel Gang, William Holmes
-
Publication number: 20230000716Abstract: A method for treatment of a headache disorder in a human subject, including selecting at least one treatment area in the nasal cavity of the human subject, said treatment area being selected from a posterior part of the nasal cavity or an anterior part of the nasal cavity, providing a device including a stimulation member arranged for vibration stimulation of the selected treatment area, and at least one expansion member provided with a channel having a plurality of openings arranged for fluid communication with the stimulation member, introducing the stimulation member into a nasal cavity of the human subject, expanding the stimulation member to a volume such that the stimulation member abuts against the tissue to exert a pressure on tissue of the selected treatment area and bringing the stimulation member to vibrate in the nasal cavity to impart vibrations to the selected treatment area, wherein the vibrations are imparted to a posterior part of the nasal cavity, to an anterior part of the nasal cavity, seqType: ApplicationFiled: September 12, 2022Publication date: January 5, 2023Applicant: CHORDATE MEDICAL ABInventors: Jan-Erik JUTO, William HOLM, Fredrik JUTO
-
Patent number: 11452666Abstract: A method for treatment of a headache disorder in a human subject, including selecting at least one treatment area in the nasal cavity of the human subject, said treatment area being selected from a posterior part of the nasal cavity or an anterior part of the nasal cavity, providing a device including a stimulation member arranged for vibration stimulation of the selected treatment area, and at least one expansion member provided with a channel having a plurality of openings arranged for fluid communication with the stimulation member, introducing the stimulation member into a nasal cavity of the human subject, expanding the stimulation member to a volume such that the stimulation member abuts against the tissue to exert a pressure on tissue of the selected treatment area and bringing the stimulation member to vibrate in the nasal cavity to impart vibrations to the selected treatment area, wherein the vibrations are imparted to a posterior part of the nasal cavity, to an anterior part of the nasal cavity, seqType: GrantFiled: July 24, 2020Date of Patent: September 27, 2022Assignee: CHORDATE MEDICAL ABInventors: Jan-Erik Juto, William Holm, Fredrik Juto
-
Publication number: 20220049217Abstract: The present invention provides improved methods for producing RPE cells from human embryonic stem cells or from other human pluripotent stem cells. The invention also relates to human retinal pigmented epithelial cells derived from human embryonic stem cells or other human multipotent or pluripotent stem cells. hRPE cells derived from embryonic stem cells am molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The hRPE cells described hemin are useful for treating retinal degenerative diseases.Type: ApplicationFiled: March 29, 2021Publication date: February 17, 2022Applicant: Astellas Institute for Regenerative MedicineInventors: Christopher Malcuit, Linda Lemieux, William Holmes, Pedro Huertas, Lucy Vilner
-
Publication number: 20210316029Abstract: A method and device for treating contaminated or potentially contaminated items is provided. The method will include the steps of placing the items in a reactor. The reactor is then sealed and ozone or ozonated gas is sent into the reactor. The items are held in the reactor long enough to complete the decontamination process. The reactor is then opened. Next there is a period of passive reaction so that the ozone can be degraded from the pores and surfaces of the items. The device provided herein includes a reactor, an ozone generator, a rack for holding said items; and a monitor for determining the level of ozone in the reactor.Type: ApplicationFiled: June 14, 2021Publication date: October 14, 2021Inventors: Mark E. Zappi, William Holmes, Andrei Chistoserdov, Wayne Sharp, Alex Zappi, Rafael Hernandez, William Chirdon
-
Publication number: 20210308312Abstract: A rack for sanitizing or cleaning medical or personal protective equipment is claimed herein. The rack has at least two stringers that run the length of the rack. The rack has at least two vertical grates that are spaced apart from each other along the stringers. The spacing between the grates will be sufficient such that a standard respiratory mask (e.g. N95) may be placed between two adjacent grates and be held in a vertical orientation.Type: ApplicationFiled: April 1, 2021Publication date: October 7, 2021Inventors: Mark E. Zappi, William Holmes, Andrei Chistoserdov, Wayne Sharp, Alex Zappi, Rafael Hernandez, William Chirdon, Don Begneaud, Thomas Broussard
-
Publication number: 20210290805Abstract: A method and device for treating contaminated or potentially contaminated items is provided. The method will include the steps of placing the items in a reactor. The reactor is then sealed and ozone or ozonated gas is sent into the reactor. The items are held in the reactor long enough to complete the decontamination process. The reactor is then opened. Next there is a period of passive reaction so that the ozone can be degraded from the pores and surfaces of the items. The device provided herein includes a reactor, an ozone generator, a rack for holding said items; and a monitor for determining the level of ozone in the reactor.Type: ApplicationFiled: March 23, 2021Publication date: September 23, 2021Inventors: Mark E. Zappi, William Holmes, Andrei Chistoserdov, Wayne Sharp, Alex Zappi, Rafael Hernandez, William Chirdon
-
Patent number: 10984393Abstract: Techniques of intelligent management of calendar items in computing systems are disclosed herein. In one embodiment, a calendar server can be configured to determine whether to accept a requested meeting utilizing a decision tree pre-configured at the server by a service provider. The decision tree contains one or more hierarchical decision nodes individually comparing one or more of parameters provided by a meeting requester to a corresponding criterion previously provided by the service provider. The calendar server can also be configured to invoke an application identified in the decision tree and provide results of the invoked application to the meeting requester in lieu of accepting the requested meeting.Type: GrantFiled: February 9, 2018Date of Patent: April 20, 2021Assignee: Microsoft Technology Licensing, LLCInventors: Anant Trivedi, William Holmes, Chandresh Kumar Jain
-
Patent number: 10981411Abstract: A method of manufacturing an image element array for a security device is disclosed.Type: GrantFiled: June 9, 2016Date of Patent: April 20, 2021Assignee: DE LA RUE INTERNATIONAL LIMITEDInventors: Adam Lister, Brian William Holmes
-
Publication number: 20210060062Abstract: The present invention provides improved methods for producing retinal pigmented epithelial (RPE) cells from human embryonic stem cells, human induced pluripotent stem (iPS), human adult stem cells, human hematopoietic stem cells, human fetal stem cells, human mesenchymal stem cells, human postpartum stem cells, human multipotent stem cells, or human embryonic germ cells. The RPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The RPE cells described herein are useful for treating retinal degenerative conditions including retinal detachment and macular degeneration.Type: ApplicationFiled: October 9, 2019Publication date: March 4, 2021Applicant: Astellas Institute for Regenerative MedicineInventors: Christopher Malcuit, Linda Lemieux, William Holmes, Pedro Huertas, Lucy Vilner
-
Patent number: 10885065Abstract: Embodiment for identifying data convergence are presented. First and second sets of data each comprising heterogeneous data are each processed in accordance with a data clustering algorithm so as to obtain a plurality of primary and secondary data clusters, respectively, where each data cluster comprising homogeneous data. The primary and secondary data clusters are analyzed with respect to time to identify convergence of data of the first and second sets of data to first and second topics, respectively. The first and second topics are compared to determine a pattern of data convergence for the first and second data sets.Type: GrantFiled: October 5, 2017Date of Patent: January 5, 2021Assignee: International Business Machines CorporationInventors: Jonathan Dunne, Karen Forde, William Holmes, Andrew Penrose
-
Publication number: 20200405571Abstract: A method for treatment of a headache disorder in a human subject, including selecting at least one treatment area in the nasal cavity of the human subject, said treatment area being selected from a posterior part of the nasal cavity or an anterior part of the nasal cavity, providing a device including a stimulation member arranged for vibration stimulation of the selected treatment area, and at least one expansion member provided with a channel having a plurality of openings arranged for fluid communication with the stimulation member, introducing the stimulation member into a nasal cavity of the human subject, expanding the stimulation member to a volume such that the stimulation member abuts against the tissue to exert a pressure on tissue of the selected treatment area and bringing the stimulation member to vibrate in the nasal cavity to impart vibrations to the selected treatment area, wherein the vibrations are imparted to a posterior part of the nasal cavity, to an anterior part of the nasal cavity, seqType: ApplicationFiled: July 24, 2020Publication date: December 31, 2020Applicant: CHORDATE MEDICAL ABInventors: Jan-Erik JUTO, William HOLM, Fredrik JUTO
-
Patent number: 10861121Abstract: A method of manufacturing a security document, including: providing a polymer substrate having first and second surfaces; and: applying an array of focussing elements to the first surface of the polymer substrate across a first region; forming an image array by: providing a die form having a surface including an arrangement of raised areas and recessed areas defining the pattern; applying a first curable material to the surface of the die form so it substantially fills the recessed areas; bringing a pattern support layer in contact with the surface of the die form so it covers the recessed areas; separating the pattern support layer from the surface of the die form so the first curable material in the recessed areas is removed from the recessed areas and retained on the pattern support layer; and at least partly curing the first curable material in one or more curing steps.Type: GrantFiled: July 11, 2016Date of Patent: December 8, 2020Assignee: DE LA RUE INTERNATIONAL LIMITEDInventors: Brian William Holmes, John Godfrey, Ian Cornes, John O'Malley, Lawrence George Commander