Abstract: A method of manufacturing a security device is provided. The method comprises providing a substrate, the substrate having opposing first and second surfaces and a relief structure formed in the first surface of the substrate. A reflection enhancing layer is applied over the first surface of the substrate such that the reflection enhancing layer at least partially overlaps the relief structure and such that a first region of the first surface of the substrate does not have the reflection enhancing layer. An absorber layer is applied over the reflection enhancing layer such that the absorber layer at least partially overlaps the reflection enhancing layer and the relief structure where the reflection enhancing layer and the relief structure overlap each other, and such that the absorber layer at least partially overlaps the first region of the first surface of the substrate.

Abstract: A diffractive security device is disclosed including at least a first diffractive structure defined in a carrier layer. The first diffractive structure is an on-axis diffractive zone plate structure of a continuously curved surface configured such that when the device is illuminated by on-axis light a first diffraction pattern generated by the first diffractive structure can be viewed from at least a first side of the device at substantially all viewing angles, the first diffraction pattern exhibiting a reference point or reference line relative to which other features of the first diffraction pattern appear to move when the viewing angle is changed.

Abstract: A diffractive security device is disclosed, including first and second diffractive structures defined in a carrier layer. The first diffractive structure is a diffractive zone plate structure of a continuously curved surface configured such that when the device is illuminated by on-axis light, a first diffraction pattern generated by the first diffractive structure can be viewed from at least a first side of the device at substantially all viewing angles, the first diffraction pattern exhibiting a reference point or reference line relative to which other features of the first diffraction pattern appear to move when the viewing angle is changed. The second diffractive structure is an off-axis diffractive structure configured such that when the device is illuminated by on-axis light a second diffraction pattern generated by the second diffractive structure can be viewed from at least the first side of the device at at least some off-axis viewing angles.

Abstract: The present invention provides improved methods for producing retinal pigmented epithelial (RPE) cells from human embryonic stem cells, human induced pluripotent stem (iPS), human adult stem cells, human hematopoietic stem cells, human fetal stem cells, human mesenchymal stem cells, human postpartum stem cells, human multipotent stem cells, or human embryonic germ cells. The RPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The RPE cells described herein are useful for treating retinal degenerative conditions including retinal detachment and macular degeneration.

Abstract: A security device is disclosed, comprising forming an array of focussing elements on first region of first surface of focussing element support layer, applying a pedestal layer comprising one transparent material onto first region of first surface of focussing element support layer applying transparent curable material to the pedestal layer or a casting tool carrying surface relief corresponding to focussing elements, over first region forming transparent curable material(s) with the casting tool bringing first surface of focussing element support layer against the casting tool that transparent curable material between the surface relief and the pedestal layer, across first region; and curing transparent curable material(s) on the pedestal layer to retain surface relief in first region; wherein focal length of focussing elements focal plane lies on first surface of focussing element support layer, or beyond first surface of focussing element support layer relative to the location of array of focussing element

Abstract: A method of applying a pattern formed of two different materials to a pattern support layer includes: providing a die form having a surface with recesses defining the pattern; applying a first curable material to a surface first region, received in some of the first region recesses and partially filling a first region recess set; applying a second curable material to some of the surface first region, the second curable material at least partially fills the first set of the first region recesses; contacting a pattern support layer with the die form surface to cover the recesses containing both the first and second curable materials; separating the pattern support layer from the die form surface, the first and second curable materials in the covered recesses removed therefrom and retained on the pattern support layer; and curing the first and second curable materials during and/or after the second and third steps.

Abstract: A security device includes: an elongate focusing structures array, the elongate axes are aligned along a first-direction, the elongate focusing structures parallel to one another periodically along a second-direction is orthogonally to the first-direction, each elongate focusing structure having an optical footprint of different elongate strips will be directed to the viewer in dependence on the viewing angle, the centre line of each optical footprint parallel with the first-direction; image elements-array overlapping the array of elongate focusing structures, the image elements-array representing elongate image slices of at least two respective images, each image slice including one or more image elements, and at least one image slice of each respective image in the optical footprint of each elongate focusing structure.

Abstract: The present invention provides improved methods for producing retinal pigmented epithelial (RPE) cells from human embryonic stem cells, human induced pluripotent stem (iPS), human adult stem cells, human hematopoietic stem cells, human fetal stem cells, human mesenchymal stem cells, human postpartum stem cells, human multipotent stem cells, or human embryonic germ cells. The RPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The RPE cells described herein are useful for treating retinal degenerative conditions including retinal detachment and macular degeneration.

Abstract: Methods of manufacturing security documents and security devices, and corresponding products, provide a lenticular device effect in a first registration zone. Viewing its appearance from two different angles in this way, the relative positioning of the focussing element array and the image array can be judged to a high degree of accuracy. If the two arrays do not have the desired relative position, this will be clearly apparent since the different first and second images will not be captured at the first and second test viewing angles.

Abstract: A method of making a security device including: (a) forming an array of focussing elements on at least a first region of a focussing element support layer, by: (a)(i) applying a first transparent curable material either to the focussing element support layer or to a casting tool carrying a surface relief corresponding to the focussing elements, over an first sub-region of the first region and applying a second transparent curable material to a second sub-region of the first region laterally offset from the first sub-region, the first and second transparent curable materials having different optical detection characteristics from one another; (a)(ii) forming the first and second transparent curable materials with the casting tool; and (a)(iii) curing the first and second transparent curable materials in the first region, so as to retain the surface relief.

Abstract: A method of manufacturing a security device is provided. The method comprises providing a substrate, the substrate having opposing first and second surfaces and a relief structure formed in the first surface of the substrate. A reflection enhancing layer is applied over the first surface of the substrate such that the reflection enhancing layer at least partially overlaps the relief structure and such that a first region of the first surface of the substrate does not have the reflection enhancing layer. An absorber layer is applied over the reflection enhancing layer such that the absorber layer at least partially overlaps the reflection enhancing layer and the relief structure where the reflection enhancing layer and the relief structure overlap each other, and such that the absorber layer at least partially overlaps the first region of the first surface of the substrate.

Abstract: Techniques of intelligent management of calendar items in computing systems are disclosed herein. In one embodiment, a calendar server can be configured to determine whether to accept a requested meeting utilizing a decision tree pre-configured at the server by a service provider. The decision tree contains one or more hierarchical decision nodes individually comparing one or more of parameters provided by a meeting requester to a corresponding criterion previously provided by the service provider. The calendar server can also be configured to invoke an application identified in the decision tree and provide results of the invoked application to the meeting requester in lieu of accepting the requested meeting.

Abstract: A security device is disclosed, comprising an array of focussing elements with regular periodicity in at least a first direction, each focusing element having an optical footprint of which different portions will be directed to the viewer in dependence on the viewing angle; and an array of image elements with regular periodicity in at least the first direction overlapping the array of focusing structures, the image elements representing portions of at least two respective images, and at least one image element from each respective image being located in the optical footprint of each focusing structure.

Abstract: A method of manufacturing a pattern on a substrate web includes providing a production tool having a surface relief structure of elevations and depressions. The elevations correspond to a desired pattern. A curable material is applied to the elevations. The material is brought into contact with a substrate web at a first location. The substrate web and surface relief structure are transported together in contact from the first location to a second location spaced from one another along the transport direction of the substrate web. The substrate web is separated from the surface relief structure at the second location whereupon the material forming the pattern is affixed to and carried by the substrate web. The material is cured by exposure to a curing energy source, either between the first and second locations and/or after the substrate web has been separated from the surface relief structure at the second location.

Abstract: A method of producing a security device comprises providing a substrate having a relief structure in/on its surface, the structure provided in a first region of the substrate. The structure in the first region a first recess or a plurality of first recesses in/on the surface of the substrate, the first recess or recesses being recessed with respect to one or more corresponding first land areas of the first region in/on the surface of the substrate. Further comprises applying a colour-shifting coating structure to the relief structure that the colour-shifting coating structure received in the first recess or recesses of the first region and on one or more first land areas. The colour-shifting coating structure applied wherein a thickness of the colour-shifting coating structure in the first recess or recesses is greater than or less than a thickness of the colour-shifting coating structure on one or more first land areas.

Abstract: Embodiment for identifying data convergence are presented. First and second sets of data each comprising heterogeneous data are each processed in accordance with a data clustering algorithm so as to obtain a plurality of primary and secondary data clusters, respectively, where each data cluster comprising homogeneous data. The primary and secondary data clusters are analyzed with respect to time to identify convergence of data of the first and second sets of data to first and second topics, respectively. The first and second topics are compared to determine a pattern of data convergence for the first and second data sets.

Abstract: A security element includes a first layer, the first layer having opposing first and second surfaces, and being formed of a substantially transparent first material having a first refractive index, the first surface of the first layer having formed therein, in a first region, an array of focussing elements. An optically variable effect generating structure is located over the first layer in a second region at least partially overlapping the array of focussing elements in the first region. An array of image elements is arranged over the array of focussing elements such that a first image, formed from at least some of the image elements, is displayed to a viewer viewing the image elements via the array of focussing elements of the first layer. The optically variable effect generating structure is also configured to display, in the second region, a second image to the viewer.

Abstract: A security element including substrate on which is disposed: in first area, a first optically variable device including a diffractive or reflective relief structure and reflection enhancing material following contours of relief structure; and, in second area, a second optically variable device including an iridescent amplitude interference material. First optically variable device is constituted by a plurality of sub-areas arranged in cyclically repeating sequence along predetermined direction of the security element, the plurality of sub-areas collectively forming first area.

Abstract: The present invention provides improved methods For producing RPE cells from human embryonic stem cells or from other human pluripotent stem cells. The invention also relates to human retinal pigmented epithelial cells derived from human embryonic stem cells or other human multipotent or pluripotent stem cells. hRPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The hRPE cells described herein are useful for treating retinal degenerative diseases.

Abstract: A display stand for securement of a photograph to a surface. The display stand is provided having a base with a bottom surface with an adhesive thereon. The display stand includes a screw that selectively moves a middle panel along a rail from a clamped to an unclamped position. A gripping surface is provided on the middle panel and a front surface.