Abstract: The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula 1

Abstract: Starburst conjugates which are composed of at least one dendrimer in association with at least one unit of a carried agricultural, pharmaceutical, or other material have been prepared. These conjugates have particularly advantageous properties due to the unique characteristics of the dendrimer.

Abstract: The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula 1

Abstract: A catalyst activator particularly adapted for use in the activation of metal complexes of metals of Group 3-10 for polymerization of ethylenically unsaturated polymerizable monomers, especially olefins, comprising: a compound corresponding to the formula: ArfzAl2Q16-z where; Q1 independently each occurrence is selected from C1-20 alkyl; Arf is a fluorinated aromatic hydrocarbyl moiety of from 6 to 30 carbon atoms; z is a number greater than 0 and less than 6, and the moiety: ArfzAl2Q16-z is an adduct of tri(fluoroarylaluminum) with from a sub-stoichiometric to a super-stoichiometric amount of a trialkylaluminum having from 1 to 20 carbons in each alkyl group.

Abstract: The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula 1

Abstract: The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula 1

Abstract: The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula 1

Abstract: Compositions comprising:

Abstract: This invention relates to heteroatom substituted cyclopentadienyl-containing ligands, metal complexes containing these ligands, catalyst systems prepared from catalyst components comprising these metal complexes. The metal complexes contain a “a” heteroatom-Cp bond or a ring heteroatom-Cp bond in the 3-position of the Cp. In preferred metal complexes the ligand is a 3-heteroatom substituted indenyl group. The catalyst systems for olefin polymerization may be used at high temperatures, are highly active and produce high molecular weight polymer.

Abstract: The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula wherein W represents —C(═O)— or —CH(OH)—; R1 represents hydrogen or hydroxy; R2 represents hydrogen; R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2; n is an integer of from 1 to 5; m is an integer 0 or 1; R3 is —COOH or —COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; each of A is hydrogen or hydroxy; and pharmaceutically acceptable salts and individual optical isomers thereof, with the proviso that where R1 and R2 are taken together to form a second bond between the carbon atoms bearing R1 and R2 or where R1 represented hydroxy, m is an integer 0.

Abstract: A composition comprising a mixture of aluminum containing Lewis acids said mixture corresponding to the formula: (Arf3Al)(AlQ13)y(—AlQ2—O—)z where; Arf is a fluorinated aromatic hydrocarbyl moiety of from 6 to 30 carbon atoms; Q1 is C1-20 alkyl; Q2 is C1-20 hydrocarbyl, optionally substituted with one or more groups which independently each occurrence are hydrocarbyloxy, hydrocarbylsiloxy, hydrocarbylsilylamino, di(hydrocarbylsilyl)amino, hydrocarbylamino, di(hydrocarbyl)amino, di(hydrocarbyl)phosphino, or hydrocarbylsulfido groups having from 1 to 20 atoms other than hydrogen, or, optionally, two or more Q2 groups may be covalently linked with each other to form one or more fused rings or ring systems; y is a number from 0 to 1.0; z is a number from 0.1 to 20; and the moieties (Arf3Al)(AlQ13)y may exist as discrete entities or dynamic exchange products.

Abstract: Compositions comprising: A) an aluminum compound corresponding to the formula AlArf3, where Arf is a fluorinated aromatic hydrocarbyl moiety of from 6 to 30 carbon atoms; B) an aluminum compound corresponding to the formula: AlArfQ1Q2, or a dimer, adduct, or mixture thereof; where: Arf is as previously defined; Q1 is Arf or a C1-20 hydrocarbyl group, optionally substituted with one or more cyclohydrocarbyl, hydrocarbyloxy, hydrocarbylsiloxy, hydrocarbylsilylamino, hydrocarbylsilyl, silylhydrocarbyl, di(hydrocarbylsilyl)amino, hydrocarbylamino, di(hydrocarbyl)amino, di(hydrocarbyl)phosphino, or hydrocarbylsulfido groups having from 1 to 20 atoms other than hydrogen, or, further optionally, such substituents may be covalently linked with each other to form one or more fused rings or ring systems; and Q2is an aryloxy, arylsulfide or di(hydrocarbyl)amido group, optionally substituted with one or more hydrocarbyl, cyclohydrocarbyl, hydrocarbyloxy, hydrocarbylsiloxy, hydrocarbylsilylamino, hydrocarbylsilyl, s

Abstract: The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula 1

Abstract: Compounds corresponding to the formula: AlArfQ1Q2, or a dimer, adduct, or mixture thereof and further mixtures with aluminum compounds of the formula AlArf3, where: Arf is a fluorinated aromatic hydrocarbyl moiety of from 6 to 30 carbon atoms; Q1 is Af or a C1-20 hydrocarbyl group, optionally substituted with one or more cyclohydrocarbyl, hydrocarbyloxy, hydrocarbylsiloxy, hydrocarbylsilylamino, hydrocarbylsilyl, silylhydrocarbyl, di(hydrocarbylsilyl)amino, hydrocarbylamino, di(hydrocarbyl)amino, di(hydrocarbyl)phosphino, or hydrocarbylsulfido groups having from 1 to 20 atoms other than hydrogen, or, further optionally, such substituents may be covalently linked with each other to form one or more fused rings or ring systems; and Q2 is an aryloxy, arylsulfide or di(hydrocarbyl)amido group, optionally substituted with one or more hydrocarbyl, cyclohydrocarbyl, hydrocarbyloxy, hydrocarbylsiloxy, hydrocarbylsilylamino, hydrocarbylsilyl, silylhydrocarbyl, di(hydrocarbylsilyl)amino, hydrocarbylamino, di(hydroca

Abstract: Starburst conjugates which are composed of at least one dendrimer in association with at least one unit of a carried agricultural, pharmaceutical, or other material have been prepared. These conjugates have particularly advantageous properties due to the unique characteristics of the dendrimer.

Abstract: The monoether adduct of a tri(fluoroaryl)aluminum compound is prepared by an exchange reaction between a trihydrocarbylaluminum compound and a tri(fluororaryl)borane compound in a hydrocarbon solvent in the presence of a C.sub.1-6 aliphatic ether in an amount from 0.9 to 1.0 moles per mole of aluminum.

Abstract: The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula ##STR1## wherein W represents --C(.dbd.O)-- or --CH(OH)--;R.sub.1 represents hydrogen or hydroxy;R.sub.2 represents hydrogen;R.sub.1 and R.sub.2 taken together form a second bond between the carbon atoms bearing R.sub.1 and R.sub.2 ;n is an integer of from 1 to 5;m is an integer 0 or 1;R.sub.3 is --COOH or --COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched each of A is hydrogen or hydroxy; andpharmaceutically acceptable salts and individual optical isomers thereof,with the proviso that where R.sub.1 and R.sub.2 are ta to form a second bond between the carbon R.sub.1 and R.sub.2 or where R.sub.1 represented hydroxy integer 0.

Abstract: Ansa bis(.mu.-substituted) Group 4 metal and aluminum compounds comprising a single Group 4 metal atom and two aluminum metal atoms corresponding to the formula: ##STR1## wherein: L' is a .pi.-bonded group,M is a Group 4 metal,J is nitrogen or phosphorus;Z is a divalent bridging group causing the complex to have an ansa structure,R' is an inert monovalent ligand;r is one or two;X independently each occurrence is a Lewis basic ligand group able to form a .mu.-bridging ligand group, and optionally the two X groups may be joined together, andA' independently each occurrence is an aluminum containing Lewis acid compound that forms an adduct with the metal complex by means of the .mu.

Abstract: The oligomers of the present invention are polythioureas having 3 to 50 recurring units derived from aromatic diamines substituted with anionic groups, and having a number average molecular weight of less than 10,000. These oligomers are water-soluble, preferably have a rigid backbone, and are pharmaceutically-acceptable. The oligomers are useful for the treatment and/or diagnosis of AIDS.

Abstract: A group conjugates having a functionalized polyaminocarboxylate chelant that form complexes with rare earth-type metal ions, covalently attached to an antibody or antibody fragment, can be used for therapeutic and/or diagnostic purposes.