Patents by Inventor William J. Ray

William J. Ray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11958839
    Abstract: Disclosed herein are novel cycloalka[b]heteroaryl compounds having CX3CR1/fractalkine receptor (CX3CR1) agonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with CX3CR1 receptor activity in animals, in particular humans.
    Type: Grant
    Filed: September 22, 2021
    Date of Patent: April 16, 2024
    Assignees: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, GOLGI NEUROSCIENCES, S.R.L.
    Inventors: Paolo Pevarello, William J. Ray, Mary Hamby, Yaima Luzardo Lightfoot, Philip Jones, Russell Thomas, Chiara Liberati, Domenica Torino, Valentina Cusano, Francesco Piscitelli, Ali Munaim Yousif, Silvia Bovolenta
  • Patent number: 11962017
    Abstract: The disclosed technology generally relates to energy storage devices, and more particularly to energy storage devices comprising frustules. According to an aspect, a supercapacitor comprises a pair of electrodes and an electrolyte, wherein at least one of the electrodes comprises a plurality of frustules having formed thereon a surface active material. The surface active material can include nanostructures. The surface active material can include one or more of a zinc oxide, a manganese oxide and a carbon nanotube.
    Type: Grant
    Filed: January 25, 2023
    Date of Patent: April 16, 2024
    Assignee: Printed Energy Pty Ltd
    Inventors: Vera N. Lockett, Yasser Salah, John G. Gustafson, William J. Ray, Sri Harsha Kolli
  • Publication number: 20240109780
    Abstract: A printed energy storage device includes a first electrode, a second electrode, and a separator between the first and the second electrode. At least one of the first electrode, the second electrode, and the separator includes frustules, for example of diatoms. The frustules may have a uniform or substantially uniform property or attribute such as shape, dimension, and/or porosity. A property or attribute of the frustules can also be modified by applying or forming a surface modifying structure and/or material to a surface of the frustules. A membrane for an energy storage device includes frustules. An ink for a printed film includes frustules.
    Type: Application
    Filed: May 1, 2023
    Publication date: April 4, 2024
    Inventors: Vera N. Lockett, John G. Gustafson, Mark D. Lowenthal, William J. Ray
  • Patent number: 11753381
    Abstract: Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.
    Type: Grant
    Filed: September 25, 2020
    Date of Patent: September 12, 2023
    Assignee: Board of Regents, The University of Texas System
    Inventors: Richard T. Lewis, Matthew Michael Hamilton, William J. Ray, Fernando Alvarez, Dana E. Pfaffinger, Naphtali Reyna, Jason Cross, Suyambu Kesava Vijayan Ramaswamy
  • Publication number: 20230282839
    Abstract: The disclosed technology generally relates to energy storage devices, and more particularly to energy storage devices comprising frustules. According to an aspect, a supercapacitor comprises a pair of electrodes and an electrolyte, wherein at least one of the electrodes comprises a plurality of frustules having formed thereon a surface active material. The surface active material can include nanostructures. The surface active material can include one or more of a zinc oxide, a manganese oxide and a carbon nanotube.
    Type: Application
    Filed: January 25, 2023
    Publication date: September 7, 2023
    Inventors: Vera N. Lockett, Yasser Salah, John G. Gustafson, William J. Ray, Sri Harsha Kolli
  • Patent number: 11718612
    Abstract: Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.
    Type: Grant
    Filed: September 8, 2020
    Date of Patent: August 8, 2023
    Assignee: Board of Regents, The University of Texas System
    Inventors: Richard T. Lewis, Matthew Hamilton, William J. Ray, Fernando Alvarez, Naphtali Reyna, Jason Cross, Suyambu Kesava Vijayan Ramaswamy
  • Patent number: 11690850
    Abstract: Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: July 4, 2023
    Assignee: Board of Regents, The University of Texas System
    Inventors: Richard T. Lewis, Matthew Hamilton, William J. Ray, Fernando Alvarez, Naphtali Reyna, Jason Cross, Suyambu Kesava Vijayan Ramaswamy
  • Publication number: 20230207836
    Abstract: A printed energy storage device includes a first electrode including zinc, a second electrode including manganese dioxide, and a separator between the first electrode and the second electrode, the first electrode, second, electrode, and separator printed onto a substrate. The device may include a first current collector and/or a second current collector printed onto the substrate. The energy storage device may include a printed intermediate layer between the separator and the first electrode. The first electrode, and the second electrode may include 1-ethyl-3-methylimidazolium tetrafluoroborate (C2mimBF4). The first electrode and the second electrode may include an electrolyte having zinc tetrafluoroborate (ZnBF4) and 1-ethyl-3-methylimidazolium tetrafluoroborate (C2mimBF4). The first electrode, the second electrode, the first current collector, and/or the second current collector can include carbon nanotubes. The separator may include solid microspheres.
    Type: Application
    Filed: November 1, 2022
    Publication date: June 29, 2023
    Inventors: Vera N. Lockett, John G. Gustafson, Alexandra E. Hartman, Mark D. Lowenthal, William J. Ray
  • Patent number: 11673811
    Abstract: A printed energy storage device includes a first electrode, a second electrode, and a separator between the first and the second electrode. At least one of the first electrode, the second electrode, and the separator includes frustules, for example of diatoms. The frustules may have a uniform or substantially uniform property or attribute such as shape, dimension, and/or porosity. A property or attribute of the frustules can also be modified by applying or forming a surface modifying structure and/or material to a surface of the frustules. A membrane for an energy storage device includes frustules. An ink for a printed film includes frustules.
    Type: Grant
    Filed: July 16, 2021
    Date of Patent: June 13, 2023
    Assignee: Printed Energy Pty Ltd
    Inventors: Vera N. Lockett, John G. Gustafson, Mark D. Lowenthal, William J. Ray
  • Publication number: 20230159508
    Abstract: Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.
    Type: Application
    Filed: August 17, 2022
    Publication date: May 25, 2023
    Inventors: Richard T. LEWIS, Matthew HAMILTON, William J. RAY, Fernando ALVAREZ, Naphtali REYNA, Suyambu Kesava Vijayan RAMASWAMY
  • Patent number: 11637292
    Abstract: The disclosed technology generally relates to energy storage devices, and more particularly to energy storage devices comprising frustules. According to an aspect, a supercapacitor comprises a pair of electrodes and an electrolyte, wherein at least one of the electrodes comprises a plurality of frustules having formed thereon a surface active material. The surface active material can include nanostructures. The surface active material can include one or more of a zinc oxide, a manganese oxide and a carbon nanotube.
    Type: Grant
    Filed: July 12, 2021
    Date of Patent: April 25, 2023
    Assignee: Printed Energy Pty Ltd
    Inventors: Vera N. Lockett, Yasser Salah, John G. Gustafson, William J. Ray, Sri Harsha Kolli
  • Patent number: 11502311
    Abstract: A printed energy storage device includes a first electrode including zinc, a second electrode including manganese dioxide, and a separator between the first electrode and the second electrode, the first electrode, second, electrode, and separator printed onto a substrate. The device may include a first current collector and/or a second current collector printed onto the substrate. The energy storage device may include a printed intermediate layer between the separator and the first electrode. The first electrode, and the second electrode may include 1-ethyl-3-methylimidazolium tetrafluoroborate (C2mimBF4). The first electrode and the second electrode may include an electrolyte having zinc tetrafluoroborate (ZnBF4) and 1-ethyl-3-methylimidazolium tetrafluoroborate (C2mimBF4). The first electrode, the second electrode, the first current collector, and/or the second current collector can include carbon nanotubes. The separator may include solid microspheres.
    Type: Grant
    Filed: May 15, 2020
    Date of Patent: November 15, 2022
    Assignee: PRINTED ENERGY Pty Ltd
    Inventors: Vera N. Lockett, John G. Gustafson, Alexandra E. Hartman, Mark D. Lowenthal, William J. Ray
  • Publication number: 20220259191
    Abstract: Disclosed herein are novel cycloalka[b]heteroaryl compounds having CX3CR1/fractalkine receptor (CX3CR1) agonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with CX3CR1 receptor activity in animals, in particular humans.
    Type: Application
    Filed: September 22, 2021
    Publication date: August 18, 2022
    Inventors: Paolo PEVARELLO, William J. RAY, Mary HAMBY, Yaima Luzardo LIGHTFOOT, Philip JONES, Russell THOMAS, Chiara LIBERATI, Domenica TORINO, Valentina CUSANO, Francesco PISCITELLI, Ali Munaim YOUSIF, Silvia BOVOLENTA
  • Publication number: 20220149232
    Abstract: A light emitting structure uses an extruded mixture of a fluorescent material and a transparent plastic to form a thin flexible substrate. The extrusion, using a slot die, forms a thin flexible film having very smooth surfaces with a uniform thickness. A transparent first conductive layer is then printed over the substrate. Pre-formed micro-LEDs are then printed over the first conductive layer, where the bottom electrodes of the LEDs contact the first conductive layer. A dielectric layer is deposited between the LEDs and exposes the top electrode of the LEDs. A second conductive layer, which may be transparent or reflective, is printed over the LEDs to electrically connect at least some of the LEDs in parallel. Primary light emitted from the LEDs energizes the fluorescent material in the substrate to emit secondary light from the substrate. Blue LED light may combine with the secondary light to create a wide gamut of colors, such as white.
    Type: Application
    Filed: October 28, 2021
    Publication date: May 12, 2022
    Inventor: William J. Ray
  • Publication number: 20220041456
    Abstract: A printed energy storage device includes a first electrode, a second electrode, and a separator between the first and the second electrode. At least one of the first electrode, the second electrode, and the separator includes frustules, for example of diatoms. The frustules may have a uniform or substantially uniform property or attribute such as shape, dimension, and/or porosity. A property or attribute of the frustules can also be modified by applying or forming a surface modifying structure and/or material to a surface of the frustules. A membrane for an energy storage device includes frustules. An ink for a printed film includes frustules.
    Type: Application
    Filed: July 16, 2021
    Publication date: February 10, 2022
    Inventors: Vera N. Lockett, John G. Gustafson, Mark D. Lowenthal, William J. Ray
  • Publication number: 20220006101
    Abstract: The disclosed technology generally relates to energy storage devices, and more particularly to energy storage devices comprising frustules. According to an aspect, a supercapacitor comprises a pair of electrodes and an electrolyte, wherein at least one of the electrodes comprises a plurality of frustules having formed thereon a surface active material. The surface active material can include nanostructures. The surface active material can include one or more of a zinc oxide, a manganese oxide and a carbon nanotube.
    Type: Application
    Filed: July 12, 2021
    Publication date: January 6, 2022
    Inventors: Vera N. Lockett, Yasser Salah, John G. Gustafson, William J. Ray, Sri Harsha Kolli
  • Patent number: 11155538
    Abstract: Disclosed herein are novel cycloalka[b]heteroaryl compounds having CX3CR1/fractalkine receptor (CX3CR1) agonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with CX3CR1 receptor activity in animals, in particular humans.
    Type: Grant
    Filed: July 23, 2020
    Date of Patent: October 26, 2021
    Assignees: Board of Regents, The University of Texas System, Axxam S.p.A.
    Inventors: Paolo Pevarello, William J. Ray, Mary Hamby, Yaima Luzardo Lightfoot, Philip Jones, Russell Thomas, Chiara Liberati, Domenica Torino, Valentina Cusano, Francesco Piscitelli, Ali Munaim Yousif, Silvia Bovolenta
  • Patent number: 11066306
    Abstract: A printed energy storage device includes a first electrode, a second electrode, and a separator between the first and the second electrode. At least one of the first electrode, the second electrode, and the separator includes frustules, for example of diatoms. The frustules may have a uniform or substantially uniform property or attribute such as shape, dimension, and/or porosity. A property or attribute of the frustules can also be modified by applying or forming a surface modifying structure and/or material to a surface of the frustules. A membrane for an energy storage device includes frustules. An ink for a printed film includes frustules.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: July 20, 2021
    Assignee: Printed Energy Pty Ltd
    Inventors: Vera N. Lockett, John G. Gustafson, Mark D. Lowenthal, William J. Ray
  • Patent number: 11063265
    Abstract: The disclosed technology generally relates to energy storage devices, and more particularly to energy storage devices comprising frustules. According to an aspect, a supercapacitor comprises a pair of electrodes and an electrolyte, wherein at least one of the electrodes comprises a plurality of frustules having formed thereon a surface active material. The surface active material can include nanostructures. The surface active material can include one or more of a zinc oxide, a manganese oxide and a carbon nanotube.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: July 13, 2021
    Assignee: Printed Energy Pty Ltd
    Inventors: Vera N. Lockett, Yasser Salah, John G. Gustafson, William J. Ray, Sri Harsha Kolli
  • Publication number: 20210154204
    Abstract: Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.
    Type: Application
    Filed: November 19, 2020
    Publication date: May 27, 2021
    Inventors: Richard T. LEWIS, Matthew HAMILTON, William J. RAY, Fernando ALVAREZ, Naphtali REYNA, Jason CROSS, Suyambu Kesava Vijayan RAMASWAMY