Patents by Inventor William J. TYLER

William J. TYLER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11534608
    Abstract: Transdermal electrical stimulation (TES) applicators that are wearable and configured to attached to a subject's pinna (ear) and adapted to apply TES to modulate the subject's cognitive and/or physiological state. These apparatuses may be configured so that they can be worn against the ear (e.g., the cymba of the ear) to deliver TES. Also described herein are methods of using them to modulate a subject's cognitive state. These TES applicators may also be adapted to function as audio headphones for concurrent delivery of TES and audible signals (e.g., music).
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: December 27, 2022
    Assignee: IST, LLC
    Inventors: William J. Tyler, Wing Law, Douglas Jeffery, Rafal Piersiak
  • Patent number: 11484713
    Abstract: Disclosed herein are an electrode assembly, an in-ear headphone, an in-ear headphone pair, and an electrode pair assembly, each for non-invasive vagus nerve stimulation. Each of the foregoing items includes a first electrode and a second electrode. An electrode assembly configured for insertion into an ear of a user includes a first electrode, a second electrode, and a shim positioned therebetween. An in-ear headphone or headphone pair may include the electrode assembly with a housing and a waveform generator. An electrode pair assembly may include a first electrode configured for insertion into a first ear of a user, and a second electrode configured for insertion into a second ear of the user. Certain embodiments further include audio components positioned within a housing of at least one in-ear headphone to deliver audio stimulation through a central channel of a first electrode or second electrode, respectively.
    Type: Grant
    Filed: August 31, 2018
    Date of Patent: November 1, 2022
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Nick Hool, William J Tyler
  • Publication number: 20220160995
    Abstract: Methods and apparatuses are described for modulating multiple integrated neural networks to alter composite sensory processes, such as audition or hearing. These methods and apparatuses may be used for therapeutic and non-therapeutic uses, including enhancing entertainment and communication, by providing a cranio-cervical tuning apparatus worn in or around the outer ear or auricle. These methods and apparatuses may include functional neurosensory bias for neurosensory scrambling neuromodulation to influence composite or multi-modal sensory processes.
    Type: Application
    Filed: January 21, 2020
    Publication date: May 26, 2022
    Inventors: Daniel Z. WETMORE, William J. TYLER
  • Publication number: 20220152389
    Abstract: Portable transdermal electrical stimulation (TES) applicators for modifying a subject's cognitive state by applying stimulation to the subject's skin. One or more electrode may be on the subject's mastoid, and/or on or near the back of the subject's neck. The portable applicators are configured and adapted to be lightweight and may be wearable, and to deliver a high-intensity TES able to evoke or enhance a predetermined cognitive effect to stimulate either the trigeminal, facial and/or cervical plexus. These TES applicators may include a pair of electrodes and a TES control module comprising a processor, a timer and a waveform generator.
    Type: Application
    Filed: January 31, 2022
    Publication date: May 19, 2022
    Inventors: Jonathan D. CHARLESWORTH, Sumon K. PAL, William J. TYLER, Daniel Z. WETMORE, Isy GOLDWASSER, Alyssa M. BOASSO, Hailey M. MORTIMORE, Rafal PIERSIAK
  • Publication number: 20220118253
    Abstract: Methods and apparatuses for non-invasive auricular and/or cervical stimulation to modulate multiple integrated neural networks. For example described herein are methods and apparatuses (e.g., devices, systems, etc.) for modulating nerves located at the base of the skull or in the neck, such as craniocervical nerves, cranial nerves, or cervical spinal nerves and/or the auricular nerve for influencing one or more biological homeostasis and related physiological processes.
    Type: Application
    Filed: January 21, 2020
    Publication date: April 21, 2022
    Inventors: Daniel Z. WETMORE, William J. TYLER
  • Publication number: 20220096504
    Abstract: Provided herein are methods and compositions for the treatment of psychological, cognitive, behavioral, and/or mood disorders, the composition comprising a 5HT agonist (e.g. psilocybin). In certain embodiments, such compositions are administered in amounts or levels high enough to provide a therapeutic effect, but insufficient to provide an adverse effect.
    Type: Application
    Filed: January 29, 2020
    Publication date: March 31, 2022
    Inventors: Judith BLUMSTOCK, William J. TYLER
  • Patent number: 11235148
    Abstract: Portable transdermal electrical stimulation (TES) applicators for modifying a subject's cognitive state by applying stimulation to the subject's skin. One or more electrode may be on the subject's mastoid, and/or on or near the back of the subject's neck. The portable applicators are configured and adapted to be lightweight and may be wearable, and to deliver a high-intensity TES able to evoke or enhance a predetermined cognitive effect to stimulate either the trigeminal, facial and/or cervical plexus. These TES applicators may include a pair of electrodes and a TES control module comprising a processor, a timer and a waveform generator.
    Type: Grant
    Filed: May 20, 2019
    Date of Patent: February 1, 2022
    Assignee: Thync Global, Inc.
    Inventors: Jonathan D. Charlesworth, Sumon K. Pal, William J. Tyler, Daniel Z. Wetmore, Isy Goldwasser, Alyssa M. Boasso, Hailey M. Mortimore, Rafal Piersiak
  • Publication number: 20210077812
    Abstract: Disclosed herein are an electrode assembly, an in-ear headphone, an in-ear headphone pair, and an electrode pair assembly, each for non-invasive vagus nerve stimulation. Each of the foregoing items includes a first electrode and a second electrode. An electrode assembly configured for insertion into an ear of a user includes a first electrode, a second electrode, and a shim positioned therebetween. An in-ear headphone or headphone pair may include the electrode assembly with a housing and a waveform generator. An electrode pair assembly may include a first electrode configured for insertion into a first ear of a user, and a second electrode configured for insertion into a second ear of the user. Certain embodiments further include audio components positioned within a housing of at least one in-ear headphone to deliver audio stimulation through a central channel of a first electrode or second electrode, respectively.
    Type: Application
    Filed: August 31, 2018
    Publication date: March 18, 2021
    Applicant: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Nick Hool, William J Tyler
  • Patent number: 10814131
    Abstract: Apparatuses (e.g., devices, systems), and methods for transdermal electrical stimulation (TES). Apparatuses described herein can be self-contained, lightweight, and wearable. The apparatuses and methods described herein be configured to apply an ensemble current waveform between the two or more electrodes, wherein the ensemble current waveform comprises a series of component waveforms that are sequentially applied, and wherein each component waveform is different from a component waveform immediately before it and wherein transitions between the component waveforms temporally correlates with transitions in the sensory experience. Also described are neurostimulators for application of transdermal electrical stimulation (TES) and methods of using them for comfortably inducing a cognitive effect. Also described are Methods and apparatuses for amplitude modulation of all or a portion of an ensemble waveform to modify a user's cognitive state by transdermal electrical stimulation (TES).
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: October 27, 2020
    Assignee: Thync Global, Inc.
    Inventors: Isy Goldwasser, William J. Tyler, Jonathan Charlesworth, Sumon K. Pal, Daniel Z. Wetmore, Douglas Jeffery, Wing Law, Jason Egnal, Anil Thakur, Remi Demers, Jay Frederick Hamlin, Rafal Piersiak
  • Publication number: 20200155790
    Abstract: Methods and apparatuses for improving sleep by transdermal electrical stimulation (TES). In general, described herein are methods for applying TES to a subject, and particularly the subject's head (e.g., temple/forehead region) and/or neck with an TES waveform adapted to improve sleep, including reducing sleep onset (falling to sleep) more quickly and/or lengthening the duration of sleep. TES waveform(s) particularly well suited to enhancing sleep are also described herein.
    Type: Application
    Filed: January 5, 2016
    Publication date: May 21, 2020
    Inventors: William J. TYLER, Alyssa M. BOASSO, Hailey M. MORTIMORE, Rhonda S. SILVA, Sumon K. PAL, Jonathan CHARLESWORTH
  • Publication number: 20200147340
    Abstract: Methods and apparatuses for improving sleep by transdermal electrical stimulation (TES). In general, described herein are methods for applying TES to a subject, and particularly the subject's head (e.g., temple/forehead region) and/or neck with an TES waveform adapted to improve sleep, including reducing sleep onset (falling to sleep) more quickly and/or lengthening the duration of sleep. TES waveform(s) particularly well suited to enhancing sleep are also described herein.
    Type: Application
    Filed: January 13, 2020
    Publication date: May 14, 2020
    Inventors: William J. TYLER, Alyssa M. BOASSO, Hailey M. MORTIMORE, Sumon K. PAL, Jonathan CHARLESWORTH
  • Publication number: 20200038658
    Abstract: Transdermal electrical stimulation (TES) applicators that are wearable and configured to attached to a subject's pinna (ear) and adapted to apply TES to modulate the subject's cognitive and/or physiological state. These apparatuses may be configured so that they can be worn against the ear (e.g., the cymba of the ear) to deliver TES. Also described herein are methods of using them to modulate a subject's cognitive state. These TES applicators may also be adapted to function as audio headphones for concurrent delivery of TES and audible signals (e.g., music).
    Type: Application
    Filed: September 30, 2019
    Publication date: February 6, 2020
    Inventors: William J. TYLER, Wing LAW, Douglas JEFFERY, Rafal PIERSIAK
  • Patent number: 10537703
    Abstract: Methods and apparatuses for improving sleep by transdermal electrical stimulation (TES). In general, described herein are methods for applying TES to a subject, and particularly the subject's head (e.g., temple/forehead region) and/or neck with an TES waveform adapted to improve sleep, including reducing sleep onset (falling to sleep) more quickly and/or lengthening the duration of sleep. TES waveform(s) particularly well suited to enhancing sleep are also described herein.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: January 21, 2020
    Assignee: Thync Global, Inc.
    Inventors: William J. Tyler, Alyssa M. Boasso, Hailey M. Mortimore, Sumon K. Pal, Jonathan Charlesworth
  • Patent number: 10485972
    Abstract: Apparatuses and methods of applying transdermal electrical stimulation (TES) to a subject to enhance a concurrent sensory experience, by applying the TES to the subject's head or head and neck from two or more electrodes that are coupled to a neurostimulator. The apparatuses and methods described herein be configured to apply an ensemble current waveform between the two or more electrodes, wherein the ensemble current waveform comprises a series of component waveforms that are sequentially applied, and wherein each component waveform is different from a component waveform immediately before it and wherein transitions between the component waveforms temporally correlates with transitions in the sensory experience. Also described herein are apparatuses and methods for applying TES to a subject's face or face and neck, wherein one end of the TES applicator (e.g., strip electrode) contacts the subject's cheek and/or mastoid. Finally, user interfaces for controlling TES are also described.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: November 26, 2019
    Assignee: Thync Global, Inc.
    Inventors: Sumon K. Pal, William J. Tyler, Jonathan D. Charlesworth, Isy Goldwasser, Daniel Z. Wetmore, Jason Egnal, Anil Thakur
  • Publication number: 20190336765
    Abstract: Portable transdermal electrical stimulation (TES) applicators for modifying a subject's cognitive state by applying stimulation to the subject's skin. One or more electrode may be on the subject's mastoid, and/or on or near the back of the subject's neck. The portable applicators are configured and adapted to be lightweight and may be wearable, and to deliver a high-intensity TES able to evoke or enhance a predetermined cognitive effect to stimulate either the trigeminal, facial and/or cervical plexus. These TES applicators may include a pair of electrodes and a TES control module comprising a processor, a timer and a waveform generator.
    Type: Application
    Filed: May 20, 2019
    Publication date: November 7, 2019
    Inventors: Jonathan D. CHARLESWORTH, Sumon K. PAL, William J. TYLER, Daniel Z. WETMORE, Isy GOLDWASSER, Alyssa M. BOASSO, Hailey M. MORTIMORE, Rafal PIERSIAK
  • Patent number: 10426945
    Abstract: Transdermal electrical stimulation (TES) applicators that are wearable and configured to attached to a subject's pinna (ear) and adapted to apply TES to modulate the subject's cognitive and/or physiological state. These apparatuses may be configured so that they can be worn against the ear (e.g., the cymba of the ear) to deliver TES. Also described herein are methods of using them to modulate a subject's cognitive state. These TES applicators may also be adapted to function as audio headphones for concurrent delivery of TES and audible signals (e.g., music).
    Type: Grant
    Filed: January 4, 2016
    Date of Patent: October 1, 2019
    Assignee: Thync Global, Inc.
    Inventors: William J. Tyler, Wing Law, Douglas Jeffery, Rafal Piersiak
  • Patent number: 10413757
    Abstract: Methods and systems for coupling ultrasound to the body, including to the head, are disclosed. The system is optionally configured to transmit ultrasound energy for transcranial ultrasound neuromodulation. Couplant assemblies are described that incorporate a semi-solid component that interfaces directly to the user's body and face of the ultrasound transducer. These couplant assemblies can be shaped, molded, or otherwise machined and, in some embodiments, contain one or more liquid, gel, or other non-solid component in an enclosed reservoir of the couplant assembly. Beneficial embodiments of ultrasound coupling assemblies described herein include those that conform to the contour of the user's body (e.g. the user's head for transcranial applications) and can easily be removed without leaving a messy residue. By having solid materials physically contacting the body, no residue is left that requires cleanup.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: September 17, 2019
    Assignee: CEREVAST MEDICAL, INC.
    Inventors: Tomokazu Sato, William J. Tyler, Philip Lamb, Daniel Z. Wetmore, Han-Ting Chang, Isy Goldwasser
  • Patent number: 10396905
    Abstract: Information is communicated to an individual by directing an acoustic signal transcranially to a target region in the brain. The target region is stimulated to produce a cognitive effect, and the cognitive effect is modulated or encoded to carry the desired information.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: August 27, 2019
    Assignee: CEREVAST MEDICAL, INC.
    Inventors: William J. Tyler, Isy Goldwasser, Robert Muratore, Sumon Pal, Tomokazu Sato, Daniel Z. Wetmore
  • Patent number: 10293161
    Abstract: Portable transdermal electrical stimulation (TES) applicators for modifying a subject's cognitive state by applying stimulation to the subject's skin. One or more electrode may be on the subject's mastoid, and/or on or near the back of the subject's neck. The portable applicators are configured and adapted to be lightweight and may be wearable, and to deliver a high-intensity TES able to evoke or enhance a predetermined cognitive effect to stimulate either the trigeminal, facial and/or cervical plexus. These TES applicators may include a pair of electrodes and a TES control module comprising a processor, a timer and a waveform generator.
    Type: Grant
    Filed: December 19, 2016
    Date of Patent: May 21, 2019
    Assignee: Thync Global, Inc.
    Inventors: Jonathan D. Charlesworth, Sumon K. Pal, William J. Tyler, Daniel Z. Wetmore, Isy Goldwasser, Alyssa M. Boasso, Hailey M. Mortimore, Rafal Piersiak
  • Patent number: D874659
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: February 4, 2020
    Assignee: NEWDIN CONTENTS Co., Ltd.
    Inventors: Daniel Z Wetmore, William J Tyler