Patents by Inventor William M. Grosse

William M. Grosse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel proteins and nucleic acids encoding same
    Publication number: 20030082174
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: May 23, 2001
    Publication date: May 1, 2003
    Inventors: Muralidhara Padigaru, Kimberly A. Spytek, Kumud Majumder, Velizar T. Tchernev, William M. Grosse, Edward S. Szekeres, John P. Alsobrook, Catherine E. Burgess, Richard A. Shimkets, Raymond J. Taupier, Stacie J. Casman, Esha A. Gangolli, John R. MacDougall, David J. Stone, Glennda Smithson
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030064369
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: July 30, 2001
    Publication date: April 3, 2003
    Inventors: Raymond J. Taupier, Muralidhara Padigaru, Luca Rastelli, Steven Kurt Spaderna, Richard A. Shimkets, Bryan D. Zerhusen, Kimberly Ann Spytek, Suresh G. Shenoy, Li Li, Vladimir Y. Gusev, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Catherine E. Burgess, Valerie L. Gerlach, Karen Ellerman, John R. MacDougall, David J. Stone, Glennda Smithson
  • Novel single nucleotide polymorphisms for olfactory receptor-like polypeptides and nucleic acids encoding the same
    Publication number: 20030059830
    Abstract: The present invention provides novel nucleic acid sequences having single nucleotide polymorphisms that encode olfactory receptor-like polypeptides and the polypeptides so encoded. Also provided are the antibodies that immunospecifically bind to these polypetides or any derivative, variant,mutant or fragment of the polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the polypetide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to uses.
    Type: Application
    Filed: October 9, 2001
    Publication date: March 27, 2003
    Inventors: John P. Alsobrook, Catherine E. Burgess, William M. Grosse, Denise M. Lepley, Muralidhara Padigaru, Kimberly A. Spytek
  • Method for automated synthesis of oligonucleotides
    Patent number: 5541314
    Abstract: Apparatus and method for the automated synthesis of DNA segments utilizing multiple reaction columns, all of which are open at the inlet end to the atmosphere of a reaction chamber. A movable reagent supply line outlet is positioned adjacent to the column inlet end to apply reagent to each of the columns according to an input sequence of delivery. The delivery sequence is under processor control. Reagents are removed from all columns simultaneously through the application of vacuum at the outlet end of each column. The device enables the parallel synthesis of large numbers of different oligonucleotide sequences of different lengths.
    Type: Grant
    Filed: August 2, 1994
    Date of Patent: July 30, 1996
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Royal A. McGraw, William M. Grosse
  • Automated synthesis of oligonucleotides
    Patent number: 5368823
    Abstract: Apparatus and method for the automated synthesis of DNA segments utilizing multiple reaction columns, all of which are open at the inlet end to the atmosphere of a reaction chamber. A movable reagent supply line outlet is positioned adjacent to the column inlet end to apply reagent to each of the columns according to an input sequence of delivery. The delivery sequence is under processor control. Reagents are removed from all columns simultaneously through the application of vacuum at the outlet end of each column. The device enables the parallel synthesis of large numbers of different oligonucleotide sequences of different lengths.
    Type: Grant
    Filed: February 11, 1993
    Date of Patent: November 29, 1994
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Royal A. McGraw, William M. Grosse