Abstract: Compounds, e.g., radioimmunoconjuguates including a chelating moiety or a metal complex thereof, a linker, and an EGFRVIII targeting moiety. Pharmaceutical compositions of such compounds and methods of treatment for conditions. e.g., cancer, using such compounds or pharmaceutical compositions.

Abstract: Techniques are described for providing a threat analysis platform capable of automating actions performed to analyze security-related threats affecting IT environments. Users or applications can submit objects (e.g., URLs, files, etc.) for analysis by the threat analysis platform. Once submitted, the threat analysis platform routes the objects to dedicated engines that can perform static and dynamic analysis processes to determine a likelihood that an object is associated with malicious activity such as phishing attacks, malware, or other types of security threats.

Abstract: Compounds and pharmaceutical compositions for use in the treatment of a disorder or disease mediated by the mTOR pathway through more selective binding to FKBP12 of the group of FK506 binding proteins (FKBPs) are disclosed. With an unusual pharmacokinetic profile and an enhanced pharmacodynamic selectivity among target FKBPs, those compounds are useful for the treatment of age- or aging-related diseases, diabetes, cancers, as well as inflammation-associated disorders.

Abstract: Techniques are described for providing a threat analysis platform capable of automating actions performed to analyze security-related threats affecting IT environments. Users or applications can submit objects (e.g., URLs, files, etc.) for analysis by the threat analysis platform. Once submitted, the threat analysis platform routes the objects to dedicated engines that can perform static and dynamic analysis processes to determine a likelihood that an object is associated with malicious activity such as phishing attacks, malware, or other types of security threats.

Abstract: Techniques are described for providing a threat analysis platform capable of automating actions performed to analyze security-related threats affecting IT environments. Users or applications can submit objects (e.g., URLs, files, etc.) for analysis by the threat analysis platform. Once submitted, the threat analysis platform routes the objects to dedicated engines that can perform static and dynamic analysis processes to determine a likelihood that an object is associated with malicious activity such as phishing attacks, malware, or other types of security threats.

Abstract: A method for estimating a parameter relating to solids recovered from a wellbore includes drilling a wellbore using a bottomhole assembly; conveying solids in the wellbore to the surface using drilling fluid; separating the drilling fluid from the solids; and continuously dropping the solids into a solids evaluator positioned above a dryer. The solids evaluator includes a chute having a vertically aligned bore in which the dropped solids reach a constant velocity, a sensor assembly generating a microwave field, and a control unit. The control unit estimates a mass flow rate of the solids based on the generated signals. The method may further include generating the signals representative of a mass flow rate of the dropped solids using the sensor assembly and using the control unit to estimate the mass flow rate of the solids based on the generated signals.

Abstract: A method for estimating a parameter relating to solids recovered from a wellbore may include drilling a wellbore using a bottomhole assembly; conveying solids in the wellbore to a surface location using a drilling fluid; separating the drilling fluid from the solids using at least one shaker; conveying the separated solids by using a conveyor; and continuously dropping the solids into a solids evaluator positioned vertically above the dryer. The solids evaluator includes a chute having a vertically aligned bore in which the dropped solids reach a constant velocity, a sensor assembly generating a microwave field in a section of the chute where the dropped solids have the constant velocity, and a control unit in signal communication with the sensor assembly. The control unit estimates a mass flow rate of the solids based on the generated signals.

Abstract: A method for estimating a parameter relating to solids recovered from a wellbore may include drilling a wellbore using a bottomhole assembly; conveying solids in the wellbore to a surface location using a drilling fluid; separating the drilling fluid from the solids using at least one shaker; conveying the separated solids by using a conveyor; and continuously dropping the solids into a solids evaluator positioned vertically above the dryer. The solids evaluator includes a chute having a vertically aligned bore in which the dropped solids reach a constant velocity, a sensor assembly generating a microwave field in a section of the chute where the dropped solids have the constant velocity, and a control unit in signal communication with the sensor assembly. The control unit estimates a mass flow rate of the solids based on the generated signals.

Abstract: A meat grinding reclamation system is disclosed herein. The system uses a first meat grinder coaxially coupled to a second meat grinder. The first meat grinder separates meat from undesired material such as gristle, hard fat, connective tissue, sinew, and bone. Most of the meat is ground, while the undesired material is remixed into a small portion of the meat and is moved from the first grinder into the second grinder. The second grinder separates remaining meat and carrier meat from the undesired material, grinding the reclaimed meat and moving it into a bin with the originally separated meat. The waste material is moved to a waste bin. Pressurized air may be used to prevent the waste material from becoming clogged in the system.

Abstract: A meat grinding reclamation system is disclosed herein. The system uses a plate having a plurality of holes through which meat is processed, and a smaller number of waste material indentations that feed waste material away from the meat into separate uniform curved openings. The center of the plate is provided with a shaft opening, which allows use of a center drive shaft across the plate.

Abstract: A meat grinding reclamation system is disclosed herein. The system uses a plate having a plurality of holes through which meat is processed, and a smaller number of waste material indentations that feed waste material away from the meat into separate uniform curved openings. The center of the plate is provided with a shaft opening, which allows use of a center drive shaft across the plate.

Abstract: A meat grinding reclamation system is disclosed herein. The system uses a plate having a plurality of holes through which meat is processed, and a smaller number of waste material indentations that feed waste material away from the meat into separate uniform curved openings. The center of the plate is provided with a shaft opening, which allows use of a center drive shaft across the plate.

Abstract: A meat grinding reclamation system is disclosed herein. The system uses a plate having a plurality of holes through which meat is processed, and a smaller number of waste material indentations that feed waste material away from the meat into separate uniform curved openings. The center of the plate is provided with a shaft opening, which allows use of a center drive shaft across the plate.

Abstract: A meat grinding reclamation system is disclosed herein. The system uses a plate having a plurality of holes through which meat is processed, and a smaller number of waste material indentations that feed waste material away from the meat into separate uniform curved openings. The center of the plate is provided with a shaft opening, which allows use of a center drive shaft across the plate.

Abstract: A method for estimating a parameter relating to solids recovered from a wellbore may include drilling a wellbore using a bottomhole assembly; conveying solids in the wellbore to a surface location using a drilling fluid; separating the drilling fluid from the solids using at least one shaker; conveying the separated solids by using a conveyor; and continuously dropping the solids into a solids evaluator positioned vertically above the dryer. The solids evaluator includes a chute having a vertically aligned bore in which the dropped solids reach a constant velocity, a sensor assembly generating a microwave field in a section of the chute where the dropped solids have the constant velocity, and a control unit in signal communication with the sensor assembly. The control unit estimates a mass flow rate of the solids based on the generated signals.

Abstract: A meat grinding reclamation system is disclosed herein. The system uses a conical feed screw. The conical feed screw is provided with a shaft and two flights. The first flight changes from a constant diameter to an expanding diameter. The second flight is provided co-helically along the shaft with a portion of the first flight. As both flights expand in diameter, meat processed through the meat grinding reclamation system accelerates, dislodging undesirable material such as gristle from the meat, before the meat decreases in velocity to present the meat for further processing.

Abstract: A meat grinding reclamation system is disclosed herein. The system uses a conical feed screw. The conical feed screw is provided with a shaft and two flights. The first flight changes from a constant diameter to an expanding diameter. The second flight is provided co-helically along the shaft with a portion of the first flight. As both flights expand in diameter, meat processed through the meat grinding reclamation system accelerates, dislodging undesirable material such as gristle from the meat, before the meat decreases in velocity to present the meat for further processing.

Abstract: A meat grinding reclamation system is disclosed herein. The system uses a plate having a plurality of holes through which meat is processed, and a smaller number of waste material sewers that feed waste material away from the meat into separate reniform exhausts. The center of the plate is provided with a shaft opening, which allows use of a center drive shaft across the plate.

Abstract: A meat grinding reclamation system is disclosed herein. The system uses a first meat grinder coaxially coupled to a second meat grinder. The first meat grinder separates meat from undesired material such as gristle, hard fat, connective tissue, sinew, and bone. Most of the meat is ground, while the undesired material is remixed into a small portion of the meat and is moved from the first grinder into the second grinder. The second grinder separates remaining meat and carrier meat from the undesired material, grinding the reclaimed meat and moving it into a bin with the originally separated meat. The waste material is moved to a waste bin. Pressurized air may be used to prevent the waste material from becoming clogged in the system.

Abstract: Phosphite dehydrogenase mutant enzymes were generated that provide relaxed cofactor specificity and increased thermostability over the wild type enzyme. The mutant enzymes are useful for nicotinamide cofactor regeneration.