Patents by Inventor William Pugh
William Pugh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20160097077Abstract: A novel class of hydroxylases is described having the amino acid sequence of SEQ ID NO: 2, 4, 6 and 8, and variants and fragments thereof having HIF hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity. An assay method monitors the interaction of the IIIF hydroxylase with a substrate. Modulators of IIIF hydroxylase are provided for use in the treatment of a condition associated with increased or decreased HIF levels or activity or for the treatment of a condition where it is desirable to modulate HIF levels or activity.Type: ApplicationFiled: November 18, 2015Publication date: April 7, 2016Applicant: ISIS INNOVATION LIMITEDInventors: Patrick Henry Maxwell, Christopher William Pugh, Peter John Ratcliffe, Christopher Joseph Schofield
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Publication number: 20160097078Abstract: A novel class of hydroxylases is described having the amino acid sequence of SEQ ID NO: 2, 4, 6 and 8, and variants and fragments thereof having HIF hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity. An assay method monitors the interaction of the HIF hydroxylase with a substrate. Modulators of HIF hydroxylase are provided for use in the treatment of a condition associated with increased or decreased HIF levels or activity or for the treatment of a condition where it is desirable to modulate HIF levels or activity.Type: ApplicationFiled: November 18, 2015Publication date: April 7, 2016Applicant: ISIS INNOVATION LIMITEDInventors: Patrick Henry Maxwell, Christopher William Pugh, Peter John Ratcliffe, Christopher Joseph Schofield
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Publication number: 20160097076Abstract: A novel class of hydroxylases is described having the amino acid sequence of SEQ ID NO: 2, 4, 6 and 8, and variants and fragments thereof having HIF hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity. An assay method monitors the interaction of the HIF hydroxylase with a substrate. Modulators of HIF hydroxylase are provided for use in the treatment of a condition associated with increased or decreased HIF levels or activity or for the treatment of a condition where it is desirable to modulate HIF levels or activity.Type: ApplicationFiled: November 18, 2015Publication date: April 7, 2016Applicant: ISIS INNOVATION LIMITEDInventors: Patrick Henry Maxwell, Christopher William Pugh, Peter John Ratcliffe, Christopher Joseph Schofield
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Patent number: 9285783Abstract: Power utilized in a local power network may be managed. The local power network may include a power management system. The power management system may communicate with one or more of a circuit controller, a switch controller, and/or an outlet controller in order to manage power utilization.Type: GrantFiled: February 15, 2013Date of Patent: March 15, 2016Assignee: InScope Energy, LLCInventors: Jason Craig, Richard Daniel Albarran, William Pugh, Kevin Cassidy
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Patent number: 9275143Abstract: Improved duplicate and near-duplicate detection techniques may assign a number of fingerprints to a given document by (i) extracting parts from the document, (ii) assigning the extracted parts to one or more of a predetermined number of lists, and (iii) generating a fingerprint from each of the populated lists. Two documents may be considered to be near-duplicates if any one of their fingerprints match.Type: GrantFiled: March 15, 2008Date of Patent: March 1, 2016Assignee: Google Inc.Inventors: William Pugh, Monika H. Henzinger
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Publication number: 20150353646Abstract: A novel class of hydroxylases is described having the amino acid sequence of SEQ ID NO: 2, 4, 6 and 8, and variants and fragments thereof having HIF hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity. An assay method monitors the interaction of the HIF hydroxylase with a substrate. Modulators of HIF hydroxylase are provided for use in the treatment of a condition associated with increased or decreased HIF levels or activity or for the treatment of a condition where it is desirable to modulate HIF levels or activity.Type: ApplicationFiled: May 15, 2015Publication date: December 10, 2015Applicant: ISIS INNOVATION LIMITEDInventors: Patrick Henry Maxwell, Christopher William Pugh, Peter John Ratcliffe, Christopher Joseph Schofield
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Publication number: 20150195285Abstract: Application-manager software authenticates a user of a client device over a channel. The authentication operation is performed using a directory service. The application-manager software presents a plurality of applications in a GUI displayed by the client device. The plurality of applications depends on the authentication, the client device, and the channel. And the plurality of applications includes a thin application and a software-as-a-service (SaaS) application. The application-manager software receives a selection as to an application from the user. If the selection is for the SaaS application, the application-manager software provisions the SaaS application. The provision includes automatically logging the user onto an account with a provider of the SaaS application using a single sign-on and connecting the user to the account so that the user can interact with the SaaS application. If the selection is for the thin application, the application manager software launches the thin application.Type: ApplicationFiled: March 23, 2015Publication date: July 9, 2015Inventors: William Pugh, Michael Eakes, Ojvind Bernander, Pradyumna Gundavaram
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Publication number: 20150156139Abstract: Methods, systems, and techniques for managing groups of entities, such as individuals, employees, or systems, and providing entitlement and access to computer resources based on group membership are provided. Example embodiments provide a Group Management System having a Group Management Engine “GME,” an Entitlement Engine, and a Provisioning Engine, which work together to allow simplified grouping of entities and providing entitlement and access to the entities based upon the group membership. In one embodiment, the GME leverages dynamic programming techniques to enable accurate, scalable systems that can manage near real time updates and changes to the group's status or to the entities' status. These components cooperate to enable provisioning of applications based upon current entitlement.Type: ApplicationFiled: February 9, 2015Publication date: June 4, 2015Inventor: William Pugh
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Patent number: 8990699Abstract: Application-manager software authenticates a user of a client device over a channel. The authentication operation is performed using a directory service. The application-manager software presents a plurality of applications in a GUI displayed by the client device. The plurality of applications depends on the authentication, the client device, and the channel. And the plurality of applications includes a thin application and a software-as-a-service (SaaS) application. The application-manager software receives a selection as to an application from the user. If the selection is for the SaaS application, the application-manager software provisions the SaaS application. The provision includes automatically logging the user onto an account with a provider of the SaaS application using a single sign-on and connecting the user to the account so that the user can interact with the SaaS application. If the selection is for the thin application, the application manager software launches the thin application.Type: GrantFiled: August 26, 2011Date of Patent: March 24, 2015Assignee: VMware, Inc.Inventors: William Pugh, Michael Eakes, Ojvind Bernander, Pradyumna Gundavaram
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Patent number: 8955151Abstract: Methods, systems, and techniques for managing groups of entities, such as individuals, employees, or systems, and providing entitlement and access to computer resources based on group membership are provided. Example embodiments provide a Group Management System having a Group Management Engine “GME,” an Entitlement Engine, and a Provisioning Engine, which work together to allow simplified grouping of entities and providing entitlement and access to the entities based upon the group membership. In one embodiment, the GME leverages dynamic programming techniques to enable accurate, scalable systems that can manage near real time updates and changes to the group's status or to the entities' status. These components cooperate to enable provisioning of applications based upon current entitlement.Type: GrantFiled: April 27, 2012Date of Patent: February 10, 2015Assignee: VMware, Inc.Inventor: William Pugh
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Publication number: 20140294842Abstract: A novel class of hydroxylases is described having the amino acid sequence of SEQ ID No. 2, 4, 6 and 8, and variants and fragments thereof having HIF hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity. An assay method monitors the interaction of the HIF hydroxylase with a substrate. Modulators of HIF hydroxylase are provided for use in the treatment of a condition associated with increased or decreased HIF levels or activity or for the treatment of a condition where it is desirable to modulate HIF levels or activity.Type: ApplicationFiled: September 16, 2013Publication date: October 2, 2014Applicant: Isis Innovation LimitedInventors: Patrick Henry Maxwell, Christopher William Pugh, Peter John Ratcliffe, Christopher Joseph Schofield
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Publication number: 20140244192Abstract: A system and method for providing monitoring of industrial equipment is disclosed. In such a system and method, one or more sensor units may be configured to generate output signals conveying information regarding power conducted to the industrial equipment. One or more power parameters may be determined based on the sensor output signals. Abnormal operations of the industrial equipment may be determined based on the power parameters and alerts responsive to the abnormal operations may be generated. In some embodiments, information regarding a present operation of the industrial equipment may be received from a control system and/or monitoring system. In those embodiments, a fault or a likelihood of fault of the control system and/or the monitoring system may be determined.Type: ApplicationFiled: February 25, 2013Publication date: August 28, 2014Applicant: InScope Energy, LLCInventors: Jason Craig, William Pugh, Richard Daniel Albarran
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Publication number: 20140126346Abstract: In an embodiment, triplets of network-enabled FCIs operate to monitor the three phases of a power distribution system. In being network-enabled, the FCIs also operate as nodes of an RF mesh network. In an embodiment, upon the detection of a power failure, the triplet of network FCIs is serially operated so as to extend their networking capabilities by approximately three times.Type: ApplicationFiled: November 5, 2012Publication date: May 8, 2014Applicant: SILVER SPRING NETWORKS, INC.Inventors: Jana VAN GREUNEN, William PUGH, Sterling HUGHES
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Publication number: 20130336608Abstract: Bearing assemblies, such as for use with a turbine engine, are disclosed. An example the bearing assembly may include an outer ring comprising an oil drainage aperture defined therein; an inner ring disposed coaxially within the outer ring, the inner ring including an oil supply aperture defined therein; and a plurality of rolling elements engaged between the outer ring and the inner ring, wherein the plurality of rolling elements are constructed of a ceramic material.Type: ApplicationFiled: March 6, 2013Publication date: December 19, 2013Applicant: General Electric CompanyInventors: Jacob Patrick Miller, Bruce Alan Carter, Michael Gilbert Johnson, Gary Paul Moscarino, David William Pugh, Jonothan Allen Scheetz, Thomas DeWitt Woodrow
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Patent number: 8535899Abstract: A novel class of hydroxylases is described having the amino acid sequence of SEQ ID NO: 2, 4, 6 and 8, and variants and fragments thereof having HIF hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity. An assay method monitors the interaction of the HIF hydroxylase with a substrate. Modulators of HIF hydroxylase are provided for use in the treatment of a condition associated with increased or decreased HIF levels or activity or for the treatment of a condition where it is desirable to modulate HIF levels or activity.Type: GrantFiled: January 12, 2010Date of Patent: September 17, 2013Assignee: Isis Innovation LimitedInventors: Patrick Henry Maxwell, Christopher William Pugh, Peter John Ratcliffe, Christopher Joseph Schofield
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Publication number: 20130166089Abstract: Power utilized in a local power network may be managed. The local power network may include a power management system. The power management system may communicate with one or more of a circuit controller, a switch controller, and/or an outlet controller in order to manage power utilization.Type: ApplicationFiled: February 15, 2013Publication date: June 27, 2013Inventors: Jason Craig, Richard Daniel Albarran, William Pugh, Kevin Cassidy
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Patent number: 8437882Abstract: Power utilized in a local power network may be managed. The local power network may include a power management system. The power management system may communicate with one or more of a circuit controller, a switch controller, and/or an outlet controller in order to manage power utilization.Type: GrantFiled: February 17, 2010Date of Patent: May 7, 2013Assignee: InScope Energy, LLCInventors: Jason Craig, Richard Daniel Albarran, William Pugh, Kevin Cassidy
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Publication number: 20120278903Abstract: Methods, systems, and techniques for managing groups of entities, such as individuals, employees, or systems, and providing entitlement and access to computer resources based on group membership are provided. Example embodiments provide a Group Management System having a Group Management Engine “GME,” an Entitlement Engine, and a Provisioning Engine, which work together to allow simplified grouping of entities and providing entitlement and access to the entities based upon the group membership. In one embodiment, the GME leverages dynamic programming techniques to enable accurate, scalable systems that can manage near real time updates and changes to the group's status or to the entities' status. These components cooperate to enable provisioning of applications based upon current entitlement.Type: ApplicationFiled: April 27, 2012Publication date: November 1, 2012Applicant: VMware, Inc.Inventor: William Pugh
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Publication number: 20120078871Abstract: Improved duplicate and near-duplicate detection techniques may assign a number of fingerprints to a given document by (i) extracting parts from the document, (ii) assigning the extracted parts to one or more of a predetermined number of lists, and (iii) generating a fingerprint from each of the populated lists. Two documents may be considered to be near-duplicates if any one of their fingerprints match.Type: ApplicationFiled: December 7, 2011Publication date: March 29, 2012Inventors: William Pugh, Monika H. Henzinger
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Publication number: 20120054625Abstract: Application-manager software authenticates a user of a client device over a channel. The authentication operation is performed using a directory service. The application-manager software presents a plurality of applications in a GUI displayed by the client device. The plurality of applications depends on the authentication, the client device, and the channel. And the plurality of applications includes a thin application and a software-as-a-service (SaaS) application. The application-manager software receives a selection as to an application from the user. If the selection is for the SaaS application, the application-manager software provisions the SaaS application. The provision includes automatically logging the user onto an account with a provider of the SaaS application using a single sign-on and connecting the user to the account so that the user can interact with the SaaS application. If the selection is for the thin application, the application manager software launches the thin application.Type: ApplicationFiled: August 26, 2011Publication date: March 1, 2012Applicant: VMWARE, INC.Inventors: William PUGH, Michael EAKES, Ojvind BERNANDER, Pradyumna GUNDAVARAM