Abstract: The invention relates to an engineered outer domain (eOD) of HIV gp120 and mutants thereof and methods of making and using the same. The mutant eODs may be advantageous for the elicitation of CD4-binding site (CD4bs)-directed broadly-neutralizing antibodies (bnAbs) and/or improve binding to mature VRC01 and/or improve binding to germline VRC01 and the germlines of other VH1-2 derived broadly-neutralizing antibodies. The mutant eODs may also include glycan-masking mutations on eOD. The present invention also includes fusions of eOD to various protein multimers to enhance immunogenicity as well as the design of cocktails of different eODs that represent the full diversity of HIV sequences within the VRC01 epitope and surroundings.

Abstract: A system for collaboratively generating and/or managing a media channel is provided. The system includes an identification component, a generation component and a permissions component. The identification component identifies a first set of media content associated with a first social group and a second set of media content associated with a second social group. The generation component generates a media channel based on the first and second sets of media content identified as being respectively associated with the first and second social groups. The permissions component grants access to the media channel based at least on permissions generated for the first and second sets of media content in connection with the respective first and second social groups.

Abstract: Among other things, a dispenser for dispensing material is provided herein. The dispenser includes a cover. The dispenser is configured to receive a container from which material is dispensed. The container is adapted to be supported by the cover. Biasing structure is adapted to apply a force to the container to facilitate dispensing the material from the container.

Abstract: The invention relates to an engineered outer domain (eOD) of HIV gp120 and mutants thereof and methods of making and using the same. The mutant eODs may be advantageous for the elicitation of CD4-binding site (CD4bs)-directed broadly-neutralizing antibodies (bnAbs) and/or improve binding to mature VRC01 and/or improve binding to germline VRC01 and the germlines of other VH1-2 derived broadly-neutralizing antibodies. The mutant eODs may also include glycan-masking mutations on eOD. The present invention also includes fusions of eOD to various protein multimers to enhance immunogenicity as well as the design of cocktails of different eODs that represent the full diversity of HIV sequences within the VRC01 epitope and surroundings.

Abstract: Among other things, a dispenser for dispensing material is provided herein. The dispenser includes a cover. The dispenser is configured to receive a container from which material is dispensed. The container is adapted to be supported by the cover. Biasing structure is adapted to apply a force to the container to facilitate dispensing the material from the container.

Abstract: The invention relates to an engineered outer domain (eOD) of HIV gp120 and mutants thereof and methods of making and using the same. The mutant eODs may be advantageous for the elicitation of CD4-binding site (CD4bs)-directed broadly-neutralizing antibodies (bnAbs) and/or improve binding to mature VRC01 and/or improve binding to germline VRC01 and the germlines of other VH1-2 derived broadly-neutralizing antibodies. The mutant eODs may also include glycan-masking mutations on eOD. The present invention also includes fusions of eOD to various protein multimers to enhance immunogenicity as well as the design of cocktails of different eODs that represent the full diversity of HIV sequences within the VRC01 epitope and surroundings.

Abstract: A system for collaboratively generating and/or managing a media channel is provided. The system includes an identification component, a generation component and a permissions component. The identification component identifies a first set of media content associated with a first social group and a second set of media content associated with a second social group. The generation component generates a media channel based on the first and second sets of media content identified as being respectively associated with the first and second social groups. The permissions component grants access to the media channel based at least on permissions generated for the first and second sets of media content in connection with the respective first and second social groups.

Abstract: A method for displaying images on a head-mounted display (HMD) device that compensates for a user's vestibulo-ocular reflex (VOR) response. The displayed HMD image is compensated for predicted eye position such that the displayed image stays centered on the fovea of the eye, during transient eye movement caused by head motion, resulting in better display readability, discernment and cognitive processing.

Abstract: A system for collaboratively generating and/or managing a media channel is provided. The system includes an identification component, a generation component and a permissions component. The identification component identifies a first set of media content associated with a first social group and a second set of media content associated with a second social group. The generation component generates a media channel based on the first and second sets of media content identified as being respectively associated with the first and second social groups. The permissions component grants access to the media channel based at least on permissions generated for the first and second sets of media content in connection with the respective first and second social groups.

Abstract: Systems and methods are disclosed for providing supplemental content in relation to embedded media. In one implementation, a processing device receives a media request from a third-party platform to incorporate a first media item within the third-party platform. The processing device identifies one or more additional media items based on the media request. The processing device provides the first media item and one or more links to at least one of the one or more additional media items in relation to the third-party platform.

Abstract: Disclosed are exemplary embodiments of woven filtration fabrics that include core-sheath spun yarns in either or both of the warp and weft directions.

Abstract: A method for annotating media objects includes receiving a completion signal after display of a first media object on a media device; selecting for display on the media device, a second media object derived from the first media object; annotating the second media object with a completion sign; dynamically determining one or more interactive elements to display with display of the second media object; annotating the second media object with one of the one or more interactive elements; and providing the annotated second media object for display on the media device.

Abstract: Systems and methods are disclosed for providing supplemental content in relation to embedded media. In one implementation, a processing device receives a media request from a third-party platform to incorporate a first media item within the third-party platform. The processing device identifies one or more additional media items based on the media request. The processing device provides the first media item and one or more links to at least one of the one or more additional media items in relation to the third-party platform.

Abstract: Disclosed are exemplary embodiments of turf reinforcement mats that include spun yarns and/or multifilament yarns in either or both of the warp and weft directions.

Abstract: Systems and methods to determine the status of transmitted audio packets. The audio packets can include digital components that are presented by a client computing device. Based on presentation variables and determinations of presentation status, the system can generate a predictive model that can be used to dynamically determines presentation values of audio packets prior to their transmission to a client computing device.

Abstract: A bird feeder is provided having a seed reservoir with a side wall that has at least one seed access opening and an adjustable feed port assembly. The feed port assembly includes a base mounted to the side wall in a fixed relationship thereto and having a central opening in communication with the seed in the reservoir. Fitted to the base is a rotatable insert having a perch coupled thereto in fixed relationship so that the perch and insert rotate as a unit. The insert is rotatable between two positions, an upright position in which the perch is below the base central opening enabling birds to feed while standing on the perch, and an upside down position in which the perch is above the base central opening, requiring birds to hang upside down from the perch to feed.

Abstract: An augmented reality system is provided and a method for controlling an augmented reality system are provided. The augmented reality system, for example, may include, but is not limited to a display, a memory, and at least one processor communicatively coupled to the display and memory, the at least one processor configured to generate image data having a first resolution at a first rate, store the generated image data in the memory, and transfer a portion of the generated image data having a second resolution to the display from the memory at a second rate, wherein the second rate is faster than the first rate and the second resolution is smaller than the first resolution. This dual rate system then enables a head-tracked augmented reality system to be updated at the high rate, reducing latency based artifacts.

Abstract: A method for displaying images on a head-mounted display (HMD) device that compensates for a user's vestibulo-ocular reflex (VOR) response. The displayed HMD image is compensated for predicted eye position such that the displayed image stays centered on the fovea of the eye, during transient eye movement caused by head motion, resulting in better display readability, discernment and cognitive processing.

Abstract: A bird feeder is provided having adjustable port access. The feeder includes a seed reservoir with a side wall that has at least one seed access opening and an adjustable feed port element. According to one embodiment, the adjustable feed port element is a feed port assembly. The feed port assembly includes a base with a rotatable insert having a perch coupled thereto in fixed relationship so that the perch and insert rotate as a unit. According to another embodiment, the adjustable feed port element rotates around the perch between a first position in which the perch is below a feed port being accessed, enabling birds to feed while standing on the perch, and a second position in which the perch is above a feed port being accessed, requiring birds to hang upside down from the perch to feed.

Abstract: Embodiments of the present disclosure provide an endotracheal tube holder and a band-locking mechanism. The endotracheal tube holder has an elongated body portion and a tube-grasping portion. The body portion may have a band-locking mechanism to secure the endotracheal tube holder to a patient. The tube-grasping portion has a tube clamp having a bite-block portion, a tube-securing portion, and at least one channel separating the bite-block portion from the tube-securing portion. The tube securing portion further has a locking assembly and the tube-grasping portion further includes at least one hinge.