Abstract: One example of a tiltrotor aircraft includes a rotor system, a pylon coupled to the rotor system, a spindle coupled to the pylon, an actuator arm coupled to the spindle, and an actuator. The actuator can cause the actuator arm to rotate, thereby causing the spindle to rotate the pylon and the rotor system. In an example, the actuator is in front of a forward spar of the wing of the tiltrotor aircraft and the actuator arm is about one-half (0.5) of an inch to about five (5) inches from the wing.

Abstract: A material transfer system for storing, transferring and dispensing viscous material, such as fluids and liquids, includes a material containment vessel with an upper region incorporating a motive force and a bottom region with a material ingress and egress opening. A diconical or other shaped force transfer device is located in the material containment area. The force transfer device is an energy transducer when the material containment is filled with highly viscous materials, such as adhesives, sealants, mastics or lubricating greases. The system's performance can be improved by applying a surface treatment to the wetted surfaces of the system to change the physical properties at the fluid/vessel interface.

Abstract: A temperature sensor assembly having a support tube defining an interior, a temperature sensor having a distal end and a proximal end located within the interior, and, a concentric ring surrounding at least a portion of the temperature sensor and the concentric ring is positioned between the temperature sensor and the support tube for holding the temperature sensor in the support tube.

Abstract: An electromechanical solenoid includes a wall defining an internal cavity, and an armature that is situated within the internal cavity and extends along a longitudinal axis. A winding is disposed radially outward of the wall and at least partially surrounds the armature. The winding is configured to provide an electromagnetic field when the winding is energized that moves the armature along the longitudinal axis within the cavity. A cross section of the armature perpendicular to the longitudinal axis has a shape that restricts rotation of the armature about the longitudinal axis within the cavity.

Abstract: The present disclosure relates to substituted fused bi- or tri-heterocyclic compounds. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating a disorder (e.g., sickle cell anemia) via inhibition of a methyltransferase enzyme selected from EHMT1 and EHMT2, by administering a substituted fused bi- or tri-heterocyclic compound disclosed herein or a pharmaceutical composition thereof to subjects in need thereof. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.

Abstract: Transdermal electrical stimulation (TES) applicators that are wearable and configured to attached to a subject's pinna (ear) and adapted to apply TES to modulate the subject's cognitive and/or physiological state. These apparatuses may be configured so that they can be worn against the ear (e.g., the cymba of the ear) to deliver TES. Also described herein are methods of using them to modulate a subject's cognitive state. These TES applicators may also be adapted to function as audio headphones for concurrent delivery of TES and audible signals (e.g., music).

Abstract: Described herein are systems and methods for securing sutures that obviate the need for tying knots. Instead of tying two ends of a suture or two sutures together with a knot, two or more suture portions can be fused or cauterized together using heat. A device can be applied to adjacent suture portions that heats the suture portions and causes the suture portions to fuse together, effectively securing the suture portions together without a knot.

Abstract: An exoscope with enhanced depth of field imaging is provided. The exoscope includes first and second sets of optical devices, the first set having a fixed image plane, the second set having a variable image plane adjacent the fixed image plane of the first set. The second set includes at least one variable device configured to change the position of the variable image plane. A beamsplitter splits light from a combined optical path of the first and second set to respective image devices of the first and second set of optical devices. A controller controls the at least one variable device to change the position of the variable image plane relative to the fixed image plane, combines images acquired by the respective image devices, and controls a display device to render a combined image.

Abstract: The disclosure features fusion proteins that are conditionally active variants of IL-2. In one aspect, the full-length polypeptides of the invention have reduced or minimal cytokine-receptor activating activity even though they contain a functional cytokine polypeptide. Upon activation, e.g., by cleavage of a linker that joins a blocking moiety, e.g., a steric blocking polypeptide, in sequence to the active cytokine, the cytokine can bind its receptor and effect signaling.

Abstract: Described here are systems, devices, and methods for delivering an implant to the orbit. In some instances, the systems may comprise a delivery device having a tongue member and a handle. The delivery device may further include an ejector configured to deliver an implant from the tongue member. The delivery device may also include a piercing member configured to create an opening in tissue. The systems may further comprise a piercing member for creating an opening in tissue. In some instances, the piercing member may have a first blade member rotatably connected to a second blade member.

Abstract: An expansion joint fitting for conveying liquid includes a radially inner bellows defining a liquid-conveying passage for conveying liquid between the first and second longitudinal ends of the expansion joint fitting. A radially outer bellows is disposed radially outward from and extending around the radially inner bellows. An annular plenum is defined between the radially inner bellows and the radially outer bellows.

Abstract: A method for modifying the wettability of a surface of an object can comprise forming on the surface of the object one or more arrays of nanofibers, wherein the one or more arrays of nanofibers includes nanofibers spaced along an X-axis and a Y-axis at the same or different intervals along either axis, the one or more arrays of nanofibers is integral with the object, and the nanofibers all have a base portion that is substantially normal to the surface. The intervals, diameter, and length of the nanofibers of the one or more arrays of nanofibers are selected so that the wettability of the surface for one or more predetermined liquids is increased or decreased relative to the wettability of the surface in the absence of the array of nanofibers.

Abstract: A method may include, by a network resource optimization system, receiving from a network node a resource request, determining a plurality of network resources based on the resource request, and determining a subset of network resources from the plurality of network resources and a network resource from the subset based on a score of each network resource. The score of each network resource may be based on a rate of acceptance of communication requests received or a number of communication sessions established. The method may include, by the network resource optimization system, transmitting a communication request to the determined network resource and receiving an acceptance from the network resource. The method may include, by the network resource optimization system, causing a selection mechanism to be activated at the network node, receiving from the network node a selection, and initiating the communication session in response to the selection.

Abstract: A surgical instrument operable to sever tissue includes a body assembly and a selectively coupleable end effector assembly. The end effector assembly may include a transmission assembly and an end effector. The body assembly includes a trigger and a casing configured to couple with the transmission assembly. An information transmission system transmits instrument information received from a sensor, for example, to a secure server via a secure gateway connected to the instrument. The instrument may be previously tested on a calibration kit to pre-determine and load surgeon-specific settings onto the instrument prior to use.

Abstract: An absorbent article having improved handling of body exudates. The absorbent article can minimize the amount of body exudates in contact with a wearer's skin and can minimize the incidence of leakage of body exudates from the absorbent article.

Abstract: Shrouds and shroud segments for gas turbine engines are provided. In one embodiment, a shroud segment for a gas turbine engine having a rotor blade stage and a nozzle stage is provided. The shroud segment comprises a forward end defining an outer wall of the rotor blade stage and an aft end defining an outer wall of the nozzle stage. The aft end defines at least a portion of an opening therethrough for receipt of a nozzle, and the forward end and the aft end form a single, continuous component. In another embodiment, a gas turbine engine is provided, having a shroud with a forward end positioned near a leading edge of a plurality of rotor blades of a rotor blade stage and an aft end positioned near a trailing edge of a plurality of nozzles of a nozzle stage. Methods of assembling a gas turbine engine also are provided.

Abstract: Apparatus and methods implementing a hardware queue management device for reducing inter-core data transfer overhead by offloading request management and data coherency tasks from the CPU cores. The apparatus include multi-core processors, a shared L3 or last-level cache (“LLC”), and a hardware queue management device to receive, store, and process inter-core data transfer requests. The hardware queue management device further comprises a resource management system to control the rate in which the cores may submit requests to reduce core stalls and dropped requests. Additionally, software instructions are introduced to optimize communication between the cores and the queue management device.

Abstract: A method to detect hardware and software errors in an embedded system is disclosed. The method includes: detecting or measuring, by a plurality of sensors, an operating state of the embedded system; operating a plurality of replicated computation engines in group synchrony, wherein the plurality of replicated computation engines are replicated instances of a single computation engine and wherein the plurality of replicated computation engines are grouped into one or more groups such that, for each group, each member of the group starts in a same processing logic state and processes same events in the same order; intercepting output of the plurality of sensors and transmitting the output to each replicated computation engine of a group in a defined order; and actuating selected computation engines of the plurality of replicated computation engines and arbitrating between outputs of the selected computation engines.

Abstract: A gas turbine engine includes a compressor section and a turbine section. The turbine section includes at least one rotor and at least one blade extending radially outwardly from the rotor to a radially outer tip. A blade outer air seal assembly is positioned radially outwardly of the radially outer tip of the blade. The blade outer air seal has forward and aft hooks. The forward and aft hooks are supported on forward and aft seal hooks of an attachment block. The attachment block has a forward case mount hook and an aft case mount hook. The attachment block is supported on a forward case hook and an aft case hook of a static casing within the engine. The forward case mount hook and the aft case mount hook on the attachment block face in a common axial direction. The forward case hook and the aft case hook face in a common axial direction which is opposed to the common axial direction. A method is also disclosed.

Abstract: Fuel additive compositions that include synergistic mixtures of one or more neutral lubricity additives and one or more monoacidic lubricity additives to provide wear and/or friction reduction in fuels.