Abstract: A method for sensitizing hypoxic tumor cells to radiation using derivatives of benzamide are disclosed. Some of the compounds useful in the method of the invention are novel.

Abstract: A method for sensitizing hypoxic tumor cells to radiation using derivatives of benzamide are disclosed. Some of the compounds useful in theREFERENCE TO GOVERNMENT GRANT OR CONTRACTThe invention described herein was made in the course of work under grant or contract from the National Institutes of Health.

Abstract: Two compounds represented by the formula ##STR1## wherein R is hydrogen or a 2-hydroxyethyl radical are reported to have minimum penetration into the brain and nerve tissues combined with maximum penetration into hypoxic tumor cells. This combination of properties makes these compounds the optimal radiosensitizers among electron-affinic 1-substituted 2-nitroinidazoles.

Abstract: Glyoxylic acid hydrocarbylsulfonylhydrazones and therapeutic compositions containing the same. Said compounds are useful in treating cancer, they being active against leukemia P-388, for example.

Abstract: Rescue apparatus comprising a life belt, a housing support for said life belt, adapted to be mounted in a substantially erect manner, releasable retaining apparatus for retaining said life belt in juxtaposition to said housing support, and remote release apparatus whereby operation of the remote release apparatus releases the retaining apparatus to cause or allow the life belt to become detached from the housing support.

Abstract: It has been the practice to (a) withdraw hot, liquid UF.sub.6 from various systems, (b) direct the UF.sub.6 into storage cylinders, and (c) transport the filled cylinders to another area where the UF.sub.6 is permitted to solidify by natural cooling. However, some hazard attends the movement of cylinders containing liquid UF.sub.6, which is dense, toxic, and corrosive.As illustrated in terms of one of its applications, the invention is directed to withdrawing hot liquid UF.sub.6 from a system including (a) a compressor for increasing the pressure and temperature of a stream of gaseous UF.sub.6 to above its triple point and (b) a condenser for liquefying the compressed gas. A network containing block valves and at least first and second portable storage cylinders is connected between the outlet of the condenser and the suction inlet of the compressor. After an increment of liquid UF.sub.

Abstract: A process for the synthesis of adriamycin and 7,9-epiadriamycin, both active antineoplastic agents, in which 7-deoxydaunomycinone, in either the 9s or racemic (.+-.) form, is employed as the starting material, the process in one embodiment also being productive of the useful intermediate compound 4-methoxy-6,11-dihydroxy-7,8-dihydro-5,9(10H),12-naphthacenetrione. The process involves converting 7-deoxydaunomicinone successively to daunomycinone, adriamycinone, 14-0-p-anisyldiphenylmethyladriamycinone and finally to adriamycin or to both adriamycin and 7,9-epiadriamycin. When producing the latter mixture of diastereomers, the 7-deoxydaunomycinone starting material is first converted to racemate form by a process involving the successive production of 7-deoxydaunorubicinol, 4-methoxy-6,11-dihydroxy-7,8-dihydro-5,9(10H), 12-naphthacenetrione, (.+-.)-4-methoxy-9-cyano-6,9,11-trihydroxy-7,8,9,10-tetrahydro-5,12-naphth acenedione, (.+-.