Abstract: A method for augmenting message streams may comprise receiving a request for augmentation of a message, the request including a parameter associated with the message. The method may further include determining a rule associated with the message. The method may further include applying the determined rule to the message parameters to select an augmentation component. The method may further include transmitting an augmented message to the requestor, the augmented message including the augmentation component.

Abstract: In vitro biomimetic models of the neonatal immune system are provided along with methods of using the models in pre-clinical assessment of infant immune cell-mediated and humoral responses to immunogenic stimulation, such as vaccination. The models include one comprising cord blood-derived T follicular helper cells and B cells, and one comprising cord blood-derived dendritic cells and CD4+ T cells. The models can be used, for example, to assess candidate vaccines via analysis of cellular responses to antigen and vaccine exposure.

Abstract: A method for augmenting message streams may comprise receiving a request for augmentation of a message, the request including a parameter associated with the message. The method may further include determining a rule associated with the message. The method may further include applying the determined rule to the message parameters to select an augmentation component. The method may further include transmitting an augmented message to the requestor, the augmented message including the augmentation component.

Abstract: Systems and methods can apply machine learning techniques to predict biological responses. One of the methods is performed by at least one processor executing executable logic including at least one machine learning model trained to predict biological responses. The method includes receiving first sequence data of a first molecular sequence, receiving second sequence data of a second molecular sequence, and predicting a biological response for the second molecular sequence based at least partly on the received first and second sequence data.

Abstract: This present disclosure provides reliable methods and apparatus for delivering a pharmaceutical active ingredient to a substrate. In some examples, the pharmaceutical active ingredient is applied to the substrate after the substrate has been fully prepared. The substrate can be an edible product or an inedible substrate. The edible product can be a baked or otherwise cooked good. In some examples, the edible product can be fruits and/or nuts. The method and apparatus for delivering the pharmaceutical agent can be configured to deliver microquantities of the pharmaceutical active ingredient to the substrate.

Abstract: There is provided methods, compositions and treatment regimens for treating cancer, or for inhibiting metastasis/recurrence of cancer in a patient using 1) a primary cancer treatment such as chemotherapy, and 2) within 12 to 120 hours post-primary treatment: a) a first therapeutic agent effective against cancer stem cells, such as a cytotoxic chemotherapy; and b) a second therapeutic agent that disrupts a downstream effect of a tissue repair signalling cascade induced by the primary treatment, including an inhibitor of neu-1 sialidase such as oseltamivir phosphate, or an inhibitor of at least one cytokine associated with stem cell enrichment such as HGF, IL-6, TGF-beta, PGE-2 or PDGF-BB. There is also provided a cancer treatment with chemotherapy agent, such as a checkpoint inhibitor, in combination with either a neuraminidase 1 inhibitor such as oseltamivir phosphate, or a COX-2 inhibitor such as celecoxib, or both.

Abstract: A mobile device having a position determination device and a mobile application configured, in response to the location of the mobile device determined by the position determination device, to: predict a transaction based at least in part on the location of the mobile device; select, based at least in part on the location of the mobile device, a first account for the transaction from a plurality of accounts identified by the identification information; and provide, via the user interface, an alert identifying the first account, before a user of the mobile device begins to make the transaction. The prediction can be made based on a location pattern relative to the location of a transaction terminal and/or the detection of short-range wireless signals of the transaction terminal.

Abstract: A mobile device having a position determination device and a mobile application configured, in response to the location of the mobile device determined by the position determination device, to: predict a transaction based at least in part on the location of the mobile device; select, based at least in part on the location of the mobile device, a first account for the transaction from a plurality of accounts identified by the identification information; and provide, via the user interface, an alert identifying the first account, before a user of the mobile device begins to make the transaction. The prediction can be made based on a location pattern relative to the location of a transaction terminal and/or the detection of short-range wireless signals of the transaction terminal.

Abstract: A structure including a barrier is described. In embodiments, a micro-electronic component may have a first face and a second face, wherein the second face includes interconnect structures and is opposite the first face. A fill material, such as a capillary underfill material (CUF), may fill a gap between the micro-electronic component and the substrate and substantially surround the interconnect structures. In embodiments, a barrier structure may be located on the surface of the substrate and along a perimeter or outside perimeter of the micro-electronic component, wherein a height of the barrier structure exceeds a height of the fill material in at least a portion of an open region of the substrate to confine the fill material to an area bordered by the barrier structure.

Abstract: There is provided methods and compositions for treating cancer or sensitizing cancer to chemotherapy in a patient by administering at least one cytokine prior to chemotherapy treatment.

Abstract: In vitro biomimetic models of the neonatal immune system are provided along with methods of using the models in pre-clinical assessment of infant immune cell-mediated and humoral responses to immunogenic stimulation, such as vaccination. The models include one comprising cord blood-derived T follicular helper cells and B cells, and one comprising cord blood-derived dendritic cells and CD4+ T cells. The models can be used, for example, to assess candidate vaccines via analysis of cellular responses to antigen and vaccine exposure.

Abstract: A mobile device having a position determination device and a mobile application configured, in response to the location of the mobile device determined by the position determination device, to: predict a transaction based at least in part on the location of the mobile device; select, based at least in part on the location of the mobile device, a first account for the transaction from a plurality of accounts identified by the identification information; and provide, via the user interface, an alert identifying the first account, before a user of the mobile device begins to make the transaction. The prediction can be made based on a location pattern relative to the location of a transaction terminal and/or the detection of short-range wireless signals of the transaction terminal.

Abstract: A mobile device having a position determination device and a mobile application configured, in response to the location of the mobile device determined by the position determination device, to: predict a transaction based at least in part on the location of the mobile device; select, based at least in part on the location of the mobile device, a first account for the transaction from a plurality of accounts identified by the identification information; and provide, via the user interface, an alert identifying the first account, before a user of the mobile device begins to make the transaction. The prediction can be made based on a location pattern relative to the location of a transaction terminal and/or the detection of short-range wireless signals of the transaction terminal.

Abstract: A wireless mobile training device has a microprocessor, a first switch, a microphone, and a speaker. The microprocessor generates a first control signal to induce the speaker to emit a first audible instruction requesting a training program identifier. The microphone generates a first input signal corresponding to a received audible training program identifier. The microprocessor generates a second control signal to induce the speaker to emit a second audible instruction associated with a predetermined training program name, if the received audible training program identifier corresponds to the predetermined training program identifier. The microprocessor determines a first time interval for completing a first user task associated with the second audible instruction based on second and third input signals from either the first switch or the microphone.

Abstract: There is provided methods for inhibiting metastasis or recurrence of a cancer in a patient after a primary treatment of the patient, and compositions for same. The method comprises administering a therapeutically effective amount of a composition for inhibiting cancer stem cell enrichment In other embodiments, the method comprises administering a therapeutically effective amount of a cancer therapy targeted towards a population of proliferating cancer stem cells in the patient.

Abstract: Some aspects include a virtual reality device configured to present to a user a virtual environment. The virtual reality device comprises a tracking device including at least one camera to acquire image data, the tracking device, when worn by the user, configured to determine a position associated with the user and a stereoscopic display device configured to display at least a portion of a representation of the virtual environment, wherein the representation of the virtual environment is based, at least in part, on the determined position associated with the user, wherein the display device and the tracking device are configured to be worn by the user.

Abstract: A cinema theater includes a seating area, a curved screen in front of the seating area and at least one projector. In one aspect, the seating area is preferably a stadium seating area and the at least one projector is positioned behind and above the stadium seating area. In another aspect, the curved screen has a center point and the at least one projector is mounted at an angle of incidence to the center point of the screen of between ±5° horizontal and ±5° vertical. In yet another aspect, the seating area that has an upper seating area and a lower seating area and the at least one projector is positioned at the front of the upper seating area.

Abstract: Some aspects include a virtual reality device configured to present to a user a virtual environment. The virtual reality device comprises a tracking device including at least one camera to acquire image data, the tracking device, when worn by the user, configured to determine a position associated with the user and a stereoscopic display device configured to display at least a portion of a representation of the virtual environment, wherein the representation of the virtual environment is based, at least in part, on the determined position associated with the user, wherein the display device and the tracking device are configured to be worn by the user.

Abstract: A wireless mobile training device has a microprocessor, a first switch, a microphone, and a speaker. The microprocessor generates a first control signal to induce the speaker to emit a first audible instruction requesting a training program identifier. The microphone generates a first input signal corresponding to a received audible training program identifier. The microprocessor generates a second control signal to induce the speaker to emit a second audible instruction associated with a predetermined training program name, if the received audible training program identifier corresponds to the predetermined training program identifier. The microprocessor determines a first time interval for completing a first user task associated with the second audible instruction based on second and third input signals from either the first switch or the microphone.