Abstract: Allergen exposure chambers (AECs) can be used to produce controlled exposure to allergenic and non-allergenic airborne particles but at present cannot be used for double-blind, placebo-controlled, randomized clinical trials currently required by regulatory authorities. Accordingly, inventive naturalistic exposure chambers (NECs) designed to mimic the environment(s) within which a typical user/individual is exposed are outlined. Further, reproducible controlled allergen dispersal is achieved via robotic allergen aerosolization systems (AAS) which provide automated movement of the allergen source within the AEC as well as structure for acquiring and/or aerosolizing-distributing the allergen. Robotic AAS can be used to acquire only, distribute only, or acquire and distribute. Robotic AAS may also provide aerosolization of two or more allergens in defined manner.

Abstract: Allergen exposure chambers (AECs) can be used to produce controlled exposure to allergenic and non-allergenic airborne particles but at present cannot be used for double-blind, placebo-controlled, randomized clinical trials currently required by regulatory authorities. Accordingly, inventive naturalistic exposure chambers (NECs) designed to mimic the environment(s) within which a typical user/individual is exposed are outlined. Further, reproducible controlled allergen dispersal is achieved via robotic allergen aerosolization systems (AAS) which provide automated movement of the allergen source within the AEC as well as structure for acquiring and/or aerosolizing—distributing the allergen. Robotic AAS can be used to acquire only, distribute only, or acquire and distribute. Robotic AAS may also provide aerosolization of two or more allergens in defined manner.

Abstract: The present disclosure relates to systems, non-transitory computer-readable media, and methods for using artificial intelligence to facilitate electronic communication between participants. For example, in one or more embodiments, the disclosed systems use artificial intelligence models to generate and provide a communication summary describing the contents of a communication. To illustrate, the disclosed systems can generate a transcript for a communication and use various computer-implemented models, such as a large language model or a set of categorization models to generate a communication summary for the transcript. In some instances, the disclosed systems use a summary template with the categorization models to incorporate certain pre-configured types of information into the communication summary.

Abstract: The present disclosure relates to systems, non-transitory computer-readable media, and methods for using artificial intelligence to facilitate electronic communication between participants. For example, in one or more embodiments, the disclosed systems perform operations to generate and provide relevant notifications to a client device participating in a communication as the communication is ongoing. In particular, during the communication, the disclosed systems can utilize one or more artificial intelligence models to analyze a communication stream, generate a transcript, enrich the transcript with contextual information, and/or retrieve digital content for use in generating and providing notifications. The disclosed systems can provide the notifications to the participating client device during the communication to assist with the discussion.

Abstract: Allergen exposure chambers (AECs) can be used to produce controlled exposure to allergenic and non-allergenic airborne particles but at present cannot be used for double-blind, placebo-controlled, randomized clinical trials currently required by regulatory authorities. Accordingly, inventive naturalistic exposure chambers (NECs) designed to mimic the environment(s) within which a typical user/individual is exposed are outlined. Further, reproducible controlled allergen dispersal is achieved via robotic allergen aerosolization systems (AAS) which provide automated movement of the allergen source within the AEC as well as structure for acquiring and/or aerosolizing—distributing the allergen. Robotic AAS can be used to acquire only, distribute only, or acquire and distribute. Robotic AAS may also provide aerosolization of two or more allergens in defined manner.

Abstract: A single-cavity multi-runner applied to oriented arrangement extrusion molding equipment of graphene fibers includes a first extrusion cavity, the first extrusion cavity includes a first inlet and a first outlet arranged opposite to each other; a first molding cavity, the first molding cavity is arranged in an inclined manner, a second inlet is arranged at the high position end, a second outlet is arranged at the low position end of the first molding cavity, and the second inlet is connected to the first outlet; flow channels, the flow channels are formed by dividing the first molding cavity using baffle plates arranged horizontally and along the flowing direction of a heat-conducting mixture; a second molding cavity, the second molding cavity includes a third inlet and a third outlet arranged opposite to each other, the third inlet is connected to the outflow end of the flow channels.

Abstract: A single-cavity multi-runner applied to oriented arrangement extrusion molding equipment of graphene fibers includes a first extrusion cavity, the first extrusion cavity includes a first inlet and a first outlet arranged opposite to each other; a first molding cavity, the first molding cavity is arranged in an inclined manner, a second inlet is arranged at the high position end, a second outlet is arranged at the low position end of the first molding cavity, and the second inlet is connected to the first outlet; flow channels, the flow channels are formed by dividing the first molding cavity using baffle plates arranged horizontally and along the flowing direction of a heat-conducting mixture; a second molding cavity, the second molding cavity includes a third inlet and a third outlet arranged opposite to each other, the third inlet is connected to the outflow end of the flow channels.

Abstract: The present invention pertains to methods of producing polypeptide of interest in cell cultures lacking glutamine. The present invention further pertains to a method of producing a protein of interest in a large scale cell culture, comprising supplementing the cell culture with nucleic acid synthesis precursors and/or corticosteroids.

Abstract: A device for preparing a thermally conductive sheet with graphene fibers in an oriented arrangement includes a first mold and a second mold. The first mold is configured to press a first cuboid block, and the second mold is configured to repeatedly press the first cuboid block. The first mold is provided with a first mold groove. A first mold cover covers an opening end of the first mold groove, and the first mold cover and the first mold are configured to press the first cuboid block. A second mold groove is arranged on one side of the second mold, and a second mold cover is arranged at an opening end of the second mold groove. A movable thickness limiting block is arranged at a side of the second mold cover adjacent to the second mold groove, and is configured to be clamped in the second mold groove.

Abstract: A device for preparing a thermally conductive sheet with graphene fibers in an oriented arrangement includes a first mold and a second mold. The first mold is configured to press a first cuboid block, and the second mold is configured to repeatedly press the first cuboid block. The first mold is provided with a first mold groove. A first mold cover covers an opening end of the first mold groove, and the first mold cover and the first mold are configured to press the first cuboid block. A second mold groove is arranged on one side of the second mold, and a second mold cover is arranged at an opening end of the second mold groove. A movable thickness limiting block is arranged at a side of the second mold cover adjacent to the second mold groove, and is configured to be clamped in the second mold groove.

Abstract: Systems and methods for time-resolved spectroscopy. Exemplary methods include: providing first, second, and third light using an excitation source; receiving first scattered light from a material responsive to the providing the first light; signaling the detector, after a delay, to provide a first spectrum of the received first scattered light; receiving second scattered light from the material responsive to the providing the second light; signaling the detector, after the delay, to provide a second spectrum of the received second scattered light; receiving third scattered light from the material responsive to the providing the third light; signaling the detector, after the delay, to provide a third spectrum of the received third scattered light; recovering a spectrum of the material using the first spectrum, second spectrum, and third spectrum; and identifying at least one molecule of the material using the recovered spectrum and a database of identified spectra.

Abstract: An apparatus for separating a ribbon of uncooked embossed dough into separated pieces patterned/shaped like the embossed pattern. The apparatus includes a pair of spaced apart rollers for receiving a ribbon of dough there between. One of rollers has a pattern embossed on its surface to emboss the ribbon of dough with the pattern. The surface embossing and the spacing between the rollers maintains the structural integrity of the embossed ribbon of dough. The apparatus has a two spaced apart rotating arms to receive the embossed dough ribbon there between. A plurality of spaced apart fingers extend outward along the length of each of the arms and are configured to tear the dough, without sticking, into dough pieces reflecting shapes embossed in the dough ribbon. The dough pieces can be dried, and patterned shaped pieces are separated out for expansion to three dimensions by cooking.

Abstract: A telescope includes a monocular assembly, an optical lens assembly, and a focus cover. The monocular assembly includes a monocular and a light-shielding tube movably sleeved at the monocular. The optical lens assembly is disposed in the light-shielding tube and is fixed on the monocular. The focus cover is detachably disposed on an end portion of the light-shielding tube and includes a tubular carrier, a focus sheet, and a covering body. The tubular carrier has a carrying portion formed on an inner side thereof, and includes a connecting portion and an accommodating portion respectively arranged at two opposite sides of the carrying portion. The connecting portion is detachably fastened to the end portion. The focus sheet is detachably positioned at the carrying portion and is arranged in the accommodating portion. The covering body is detachably fastened to the accommodating portion for shielding the focus sheet.

Abstract: An apparatus for separating a ribbon of uncooked embossed dough into separated pieces patterned/shaped like the embossed pattern. The apparatus includes a pair of spaced apart rollers for receiving a ribbon of dough there between. One of rollers has a pattern embossed on its surface to emboss the ribbon of dough with the pattern. The surface embossing and the spacing between the rollers maintains the structural integrity of the embossed ribbon of dough. The apparatus has a two spaced apart rotating arms to receive the embossed dough ribbon there between. A plurality of spaced apart fingers extend outward along the length of each of the arms and are configured to tear the dough, without sticking, into dough pieces reflecting shapes embossed in the dough ribbon. The dough pieces can be dried, and patterned shaped pieces are separated out for expansion to three dimensions by cooking.

Abstract: A telescope includes a monocular assembly, an optical lens assembly, and a focus cover. The monocular assembly includes a monocular and a light-shielding tube movably sleeved at the monocular. The optical lens assembly is disposed in the light-shielding tube and is fixed on the monocular. The focus cover is detachably disposed on an end portion of the light-shielding tube and includes a tubular carrier, a focus sheet, and a covering body. The tubular carrier has a carrying portion formed on an inner side thereof, and includes a connecting portion and an accommodating portion respectively arranged at two opposite sides of the carrying portion. The connecting portion is detachably fastened to the end portion. The focus sheet is detachably positioned at the carrying portion and is arranged in the accommodating portion. The covering body is detachably fastened to the accommodating portion for shielding the focus sheet.

Abstract: Methods and media for compensating for irregular motion in three-dimensional spectroscopy are provided herein. Exemplary methods include: receiving a plurality of spectrographs for a series of respective locations and corresponding images of the respective locations, each spectrograph of the plurality of spectrographs being produced using a spectrographic data set of a plurality of spectrographic data sets, each of the plurality of spectrographic data sets being measured by a spectrometer and each of the corresponding images being captured by a camera at substantially the same time, the spectrometer being coupled to the camera such that the spectrometer and camera move in tandem and at least partially share the same point of view; generating a continuous image using the images; identifying a respective corresponding position in the continuous image for each spectrograph, such that each spectrograph is a measurement of the respective position; and associating each spectrograph with the respective position.

Abstract: Systems and methods for time-resolved spectroscopy. Exemplary methods include: providing first, second, and third light using an excitation source; receiving first scattered light from a material responsive to the providing the first light; signaling the detector, after a delay, to provide a first spectrum of the received first scattered light; receiving second scattered light from the material responsive to the providing the second light; signaling the detector, after the delay, to provide a second spectrum of the received second scattered light; receiving third scattered light from the material responsive to the providing the third light; signaling the detector, after the delay, to provide a third spectrum of the received third scattered light; recovering a spectrum of the material using the first spectrum, second spectrum, and third spectrum; and identifying at least one molecule of the material using the recovered spectrum and a database of identified spectra.

Abstract: Systems and methods for adjusting for non-invasive measurement of biological analytes. Exemplary methods include: illuminating an analyte using first light, the first light having a first excitation wavelength; detecting a first spectrum from the analyte illuminated by the first light, the first spectrum including a first Raman signal and fluorescence; illuminating the analyte using second light, the second light having a second excitation wavelength; detecting a second spectrum; illuminating the analyte using third light, the third light having a third excitation wavelength; detecting a third spectrum; recovering the first Raman signal using the first spectrum, the second spectrum, and the third spectrum using an inverse transform; and using the first Raman signal to identify and measure at least one molecule of the analyte using a database of identified Raman signals.

Abstract: Methods and media for compensating for irregular motion in three-dimensional spectroscopy are provided herein. Exemplary methods include: receiving a plurality of spectrographs for a series of respective locations and corresponding images of the respective locations, each spectrograph of the plurality of spectrographs being produced using a spectrographic data set of a plurality of spectrographic data sets, each of the plurality of spectrographic data sets being measured by a spectrograph and each of the corresponding images being captured by a camera at substantially the same time, the spectrograph being coupled to the camera such that the spectrograph and camera move in tandem and at least partially share the same point of view; generating a continuous image using the images; identifying a respective corresponding position in the continuous image for each spectrograph, such that each spectrograph is a measurement of the respective position; and associating each spectrograph with the respective position.

Abstract: The present invention pertains to a cell culture medium comprising media supplements that are shown to control recombinant protein glycosylation and/or cell culture in a controlled or modulated (shifted) temperature to control recombinant protein glycosylation and/or cell culture with controlled or modulated seed density to control recombinant protein glycosylation, and methods of using thereof. The present invention further pertains to a method of controlling or manipulating glycosylation of a recombinant protein of interest in a large scale cell culture.