Patents by Inventor Wilson Or

Wilson Or has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heteroaryl-Pyrimidinone Compounds as PDE2 Inhibitors
    Publication number: 20180280390
    Abstract: The present invention is directed to substituted pyrimidinone compounds of formula (I) which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis, Parkinson's disease, Parkinson's disease dementia (PDD), or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.
    Type: Application
    Filed: May 2, 2016
    Publication date: October 4, 2018
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Dong-Ming Shen, Jonathan E. Wilson, Troy McCracken
  • POLYMER CONJUGATE VACCINES
    Publication number: 20180280524
    Abstract: Monomers and copolymers are provided that both target antigen presenting cells (APCs) and activate toll-like receptor (TLR) on the APCs. In some embodiments, compositions and methods involve a polymer that targets the mannose receptor on APCs, in addition to activating a TLR. These can then be conjugated to protein antigens to efficiently target antigens to DCs and simultaneously induce the up-regulation of co-stimulatory molecules that are essential for effective T cell activation. This copolymer is a more efficient activator of DCs, as measured by the surface expression of co-stimulatory molecules and the release of proinflammatory cytokines, than the monomeric form the TLR agonist used in the polymer formulation. Aspects of the disclosure relate to novel compounds, methods, and compositions for treating diseases using the compounds, copolymers, and compositions described herein.
    Type: Application
    Filed: September 29, 2016
    Publication date: October 4, 2018
    Inventors: Jeffrey A. Hubbell, David Scott Wilson, Sachiko Hirosue
  • DYNAMIC OVERRIDING OF CONTROL BEAM MONITORING CONFIGURATION
    Publication number: 20180287686
    Abstract: Methods, systems, and devices for wireless communication are described that support overriding a beam monitoring pattern for control channel transmissions based on channel conditions between a user equipment and a base station. A base station may select a beam monitoring pattern for transmitting control channel transmissions, which may include a pattern in which two or more beams are used for control channel transmissions. In the event that a first beam of the beams used in the beam monitoring pattern meets certain metrics, the use of one or more additional beams according to the beam monitoring pattern may be overridden and transmissions continued using the first beam. The metrics for continuing use of the first beam may include channel quality metrics, a number of consecutive successful transmissions using the first beam, one or more other metrics, or any combination thereof.
    Type: Application
    Filed: March 5, 2018
    Publication date: October 4, 2018
    Inventors: Makesh Pravin John Wilson, Tao Luo, Jing Sun, Andrei Dragos Radulescu, Aleksandar Damnjanovic, Arumugam Chendamarai Kannan
  • VIRTUAL OBJECT USER INTERFACE DISPLAY
    Publication number: 20180286126
    Abstract: Methods, computing devices and head-mounted display devices for displaying user interface elements with virtual objects are disclosed. In one example, a virtual object and one or more user interface elements are displayed within a physical environment. User input is received that moves one or more of the virtual object and the one or more user interface elements. One or more of the virtual object and the one or more user interface elements are determined to be within a predetermined distance of a physical surface. Based at least on this determination, the one or more user interface elements are displayed on the surface.
    Type: Application
    Filed: April 3, 2017
    Publication date: October 4, 2018
    Applicant: Microsoft Technology Licensing, LLC
    Inventors: Julia Schwarz, Bo Robert Xiao, Hrvoje Benko, Andrew Wilson
  • LASER REMELTING TO ENHANCE CYLINDER BORE MECHANICAL PROPERTIES
    Publication number: 20180283310
    Abstract: An engine block, an automotive structure, and a method of coating an inner surface of an engine cylinder bore of an engine cylinder are provided. The method includes providing an inner bore substrate defining an inner surface of the engine cylinder bore, the inner bore substrate being formed of a first material. The method further includes disposing a thermal spray coating onto the inner surface of the engine cylinder bore. The thermal spray coating is formed of a second material that is different than the first material. The method also includes melting at least a portion of the thermal spray coating with a laser after performing the step of disposing the thermal spray coating onto the inner surface of the engine cylinder bore. The automotive structure and the engine block have a substrate covered by a thermal spray coating and laser remelted sections anchoring the coating to the substrate.
    Type: Application
    Filed: April 4, 2017
    Publication date: October 4, 2018
    Inventors: Huaxin Li, Daniel J. Wilson, Martin S. Kramer, Dale A. Gerard
  • TIMER BASED UE SIDE BEAM SWEEPING FOR QUICK LINK BLOCKAGE RECOVERY
    Publication number: 20180288757
    Abstract: A base station may maintain multiple beam pair links, with one being actively used for communication. The active beam pair may become blocked. Accordingly, it may be necessary to switch to another beam pair. The apparatus may be an apparatus for wireless communication. The apparatus for wireless communication may include a memory and at least one processor coupled to the memory. The at least one processor is configured to determine a set of active beam pairs including at least a first beam pair and a second beam pair and select the first beam pair. The at least one processor is also configured to predict that the first beam pair is blocked, the prediction based on an expiration of a timer and sweep through the set of active beam pairs based on predicting that the first beam pair is blocked.
    Type: Application
    Filed: March 21, 2018
    Publication date: October 4, 2018
    Inventors: Jing SUN, Tao LUO, Makesh Pravin JOHN WILSON, Xiao feng WANG
  • Method to provide meta-stable operation of a DC microgrid comprising a pulsed load
    Patent number: 10090764
    Abstract: A Hamiltonian surface shaping power flow control (HSSPFC) method is used to analyze the meta-stability and adjust pulsed power loads on a DC electric power distribution network. Pulsed power loads are nonlinear, time-variant systems that cause nonlinear limit-cycles. During the on periods of a pulsed load, the system can be in an unstable state and is damped back to stability during the off state of the load. Therefore, over the entire period of the pulse the system may only be assessed as meta-stable. As shown through simulation, HIL and hardware results, the HSSPFC method is more accurate than the other small-signal approaches, such as Eigenvalues, Nyquist, and Floquet theory, and can reveal important details about the transient responses and performance.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: October 2, 2018
    Assignees: National Technology & Engineering Solutions of Sandia, LLC, Michigan Technological University
    Inventors: David G. Wilson, Wayne W. Weaver, Rush D. Robinett, III, Ronald Matthews, Steven F. Glover
  • Object movement control apparatus and method
    Patent number: 10086297
    Abstract: Described herein is an apparatus and method to convey an object through the air in a controlled and repeatable manner. The apparatus may comprise an object attached to at least one resilient member, the resilient member or members constraining object movement in a substantially vertical y-axis direction. The apparatus may also comprise at least one support member coupled to the at least one resilient member, and the support member or members constrain object movement in a substantially horizontal x-axis direction. In use, the resilient member is energized, movement initiated, and object movement then occurs in both an x-axis and y-axis direction, the movement path substantially governed by the resilient member(s) and the support member(s). The apparatus and method may allow the object to experience a variety of movement sensations, one being the feeling of flight or gliding.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: October 2, 2018
    Assignee: Bungy New Zealand Limited
    Inventors: Henry Van Asch, David Mitchell, Tim Porter, Geoff Wilson, Kevin Andrew Wright
  • Asynchronous online viewing party
    Patent number: 10091460
    Abstract: Various embodiments of systems, methods, computer devices, and computer software for providing an asynchronous online viewing party are provided. One embodiment comprises a system for providing an online viewing party. One such system comprises: a server operatively coupled to a database for supporting the online viewing party, the database comprising: content to be asynchronously provided to participants of the online viewing party; and time-based events provided by one or more of the participants, the time-based events associated with the content and linked to corresponding locations in the content; and a user interface configured to interface with the server, the user interface comprising logic configured to display the content and the time-based events.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: October 2, 2018
    Assignee: Disney Enterprises, Inc.
    Inventors: Jonathan David Barsook, David Christian Ehlers, Jason Richard Grant, Khai Tuan Tran, David John Watson, Nicklas Lee Wilson
  • Polynucleotides encoding cyclohexanone monooxygenases
    Patent number: 10087426
    Abstract: The present invention relates to non-naturally occurring polypeptides useful for preparing armodafinil, polynucleotides encoding the polypeptides, and methods of using the polypeptides. The non-naturally occurring polypeptides of the present invention are effective in carrying out biocatalytic conversion of the (i) 2-(benzhydrylsulfinyl)acetamide to (?)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide (armodafinil), or (ii) benzhydryl-thioacetic acid to (R)-2-(benzhydrylsulfinyl)acetic acid, which is a pivotal intermediate in the synthesis of armodafinil, in enantiomeric excess.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: October 2, 2018
    Assignee: Codexis, Inc.
    Inventors: Ee Lui Ang, Oscar Alvizo, Behnaz Behrouzian, Michael D. Clay, Steven J. Collier, Ellen D. Eberhard, Fu Fan, Shiwei Song, Derek J. Smith, Magnus Widegren, Robert Wilson, Junye Xu, Jun Zhu
  • Piezoelectric jetting system and method
    Patent number: 10090453
    Abstract: A system and method for jetting a viscous material includes an electronic controller and a jetting dispenser operatively coupled with the electronic controller. The jetting dispenser includes an outlet orifice and a piezoelectric actuator operatively coupled with a movable shaft. The jetting dispenser is under control of the electronic controller for causing said piezoelectric actuator to move the shaft and jet an amount of the viscous material from the outlet orifice. The electronic controller sends a waveform to the piezoelectric actuator to optimize control of the jetting operation.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: October 2, 2018
    Assignee: Nordson Corporation
    Inventors: Scott A. Conner, John D. Jones, Bryan Teece, Wilson A. Villegas
  • Remote support of computing devices
    Patent number: 10089633
    Abstract: A customer support application provides screen sharing of the user's computing device with a remote customer support agent, thereby enabling the customer support agent to view the content displayed on the user's device. The customer support agent can provide guidance to the user by transmitting support content back to the user's computing device, where the support content is displayed as an overlay on top of the user's normal user interface content. The screen sharing and support content may be supplemented with live audio and video communications between the user and the remote customer support agent, and the multiple modes of communication may be prioritized to maintain quality in the preferred communication mode.
    Type: Grant
    Filed: August 13, 2013
    Date of Patent: October 2, 2018
    Assignee: AMAZON TECHNOLOGIES, INC.
    Inventors: Pirasenna Thiyagarajan, James Arthur Wilson, Jennifer Piksum Yick, Rexford Jay Tibbens
  • Selective blocking of background activity
    Patent number: 10088892
    Abstract: Controlling background activity in a computing device or system during a low-power mode is described. In some example techniques, when a computing device or system is in a low power mode, a determination is made whether to block one or more trigger events from causing an activation of one or more respective background task operations. Based at least in part on the determination, at least one trigger event may be allowed to cause an activation of a respective background task operation during the low power mode.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: October 2, 2018
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Hari Pulapaka, Alain Gefflaut, Jon Robert Berry, Emily Wilson, Qian Liu
  • Guard for mouth
    Patent number: 10085821
    Abstract: A mouthpiece includes first and second bodies over teeth of a user. The bodies comprise frames with a bite pad between upper and lower teeth. The bite pad is molded in the frames while in situ in the mouth. The frames, prior to having the bite pads in place are hollow spaces with spanning elements spaced from each other projecting into the hollow space between a top and a bottom of each of the frames. An upper wall of the frame includes an inwardly directed lip directed towards a space inside the frames. A lower wall of the frame is extended in height relatively longer than the upper wall. A shim or a clip is inserted between the incisor edges for facilitating alignment of the incisor edges. The connector includes a slot for accommodating an extension of the shim when the shim is located with the connector.
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: October 2, 2018
    Assignee: MDM
    Inventors: David Scott Frey, Scott Harold Wilson, Kyle Andrew Buzzard
  • Electronic devices with masking layers
    Patent number: 10090876
    Abstract: An electronic device may have transparent structures. The transparent structures may include a transparent member such as a transparent button member, a transparent member that serves as a display cover layer, a transparent member that covers a sensor such as a touch sensor, or other transparent member. The transparent member may have an inner surface that is covered with an opaque masking layer that is free of materials that discolor upon light exposure and that is formed from a layer of polymer and light-scattering inclusions such as solid particles, hollow microspheres, porous particles, and voids. A protective layer such as an inorganic layer may be formed over the polymer layer. A fingerprint sensor, touch sensor, or other structures may be attached to the opaque masking layer using a layer of adhesive.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: October 2, 2018
    Assignee: Apple Inc.
    Inventors: Naoto Matsuyuki, James R. Wilson, Matthew S. Rogers
  • Holder
    Patent number: D829466
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: October 2, 2018
    Assignee: Spectrum Diversified Designs, LLC
    Inventors: Aaron Goodman, Courtney Wilson
  • Display screen or a portion thereof with a graphical user interface
    Patent number: D829752
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: October 2, 2018
    Assignee: ADP, LLC
    Inventors: Ketan Chauhan, Eric Zitaner, Hafeez Raji, Justin Torrento, David Turetsky, Vikas Saini, Richard Wilson, Emily Scala, Philip Charron, Christopher Hungate
  • Display screen or a portion thereof with a graphical user interface
    Patent number: D829753
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: October 2, 2018
    Assignee: ADP, LLC
    Inventors: Ketan Chauhan, Eric Zitaner, Hafeez Raji, Justin Torrento, David Turetsky, Vikas Saini, Richard Wilson, Emily Scala, Philip Charron, Christopher Hungate
  • Display screen or a portion thereof with a graphical user interface
    Patent number: D829754
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: October 2, 2018
    Assignee: ADP, LLC
    Inventors: Ketan Chauhan, Eric Zitaner, Hafeez Raji, Justin Torrento, David Turetsky, Vikas Saini, Richard Wilson, Emily Scala, Philip Charron, Christopher Hungate
  • Modular housing unit
    Patent number: D829925
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: October 2, 2018
    Assignee: Kasita, LLC
    Inventors: Remy Labesque, Jeff Wilson, Taylor Wilson