Abstract: A system for spraying a coating material to a substrate includes an optical sensor that monitors a thickness, a controller that generates a first signal corresponding to an amount of gas propellant to be heated, a second signal corresponding to a temperature to which the gas propellant is to be heated, a third signal corresponding to an amount of a solid powder composition to be mixed with the heated gas, and a fourth signal corresponding to a distance between the nozzle and the substrate, a first regulator that supplies an amount of gas propellant corresponding to the first signal, a heater that heats the gas propellant to the temperature corresponding to the second signal, a second regulator that supplies an amount of solid powder composition corresponding to the third signal, and an actuator that moves the nozzle corresponding to the fourth signal.

Abstract: User interface navigation on a personal electronics device based on movements of a crown is disclosed. The device can select an appropriate level of information arranged along a z-axis for display based on crown movement. The navigation can be based on an angular velocity of the crown.

Abstract: This disclosure relates to compounds according to Formula (I), salts, prodrugs and pharmaceutical formulation comprising the compound are provided herein for the treatment of CXCR4 and CCR5 related conditions. The conditions may include viral infections, abnormal cellular proliferation, retinal degeneration and inflammatory diseases, or the compounds may be used as immunostimulants or immunosuppressants. Furthermore, the compounds may be used in combination with another active ingredient selected from an antiviral agent or chemotherapeutic agent.

Abstract: The present disclosure relates to immunoassays for NF-L performed on liquid samples derived from physiological fluids such as venous blood to detect the presence or absence of a physiological condition by quantifying one or a combination of NF-L determinations at concentrations indicative of the condition.

Abstract: An exhaust gas heater system for an exhaust system of an internal combustion engine includes a housing and a heating element. The housing includes an outer peripheral wall disposed about a central axis and defining an interior hollow space configured to receive exhaust gas from an exhaust pipe of the exhaust system such that the exhaust gas flows through the interior hollow space. The heating element is positioned within the hollow space and including a first end and a second end. The heating element includes a first section proceeding in a first direction and a second section proceeding in a second direction. The support structure is configured to extend along a path conforming to a path of the first and second sections.

Abstract: A cable support includes a support body with a saddle configured to support one or more cables, and a stem and a leg that extend from opposite ends of the saddle. A securing member is coupled to the leg. The securing member is movable between a first configuration configured to secure one or more cables within the saddle and a second configuration configured to permit one or more cables to be moved into or out of the saddle. The leg including a retaining tab that releasably secures the securing member in the second configuration.

Abstract: A staple cartridge for a surgical instrument includes a cartridge body extending along a longitudinal axis and having an upper deck. Pockets extend through the upper deck for receiving respective staples. The staple cartridge also includes a pan coupled to the cartridge body. The pan includes a laterally-opposed pair of sidewalls spaced apart from each other to define a trough sized and configured to receive the cartridge body. The pan also includes a retention tab extending laterally outwardly from a sidewall and longitudinally between proximal and distal ends. The retention tab defines a recess extending laterally outwardly from the trough. The recess opens through the sidewall at at least one of the proximal or distal ends. The pan further includes a relief slot extending through the sidewall adjacent to the at least one of the proximal or distal ends such that the relief slot opens directly into the recess.

Abstract: An apparatus including a body, a shaft assembly extending distally from the body, and an end effector configured to grasp and transmit RF energy to the tissue. The end effector includes a first jaw having a first tissue grasping feature and a second jaw. The second jaw is pivotably coupled to the first jaw between an open position, a partially closed position, and a closed position. The second jaw includes a proximal taper having a proximal electrode surface, a distal taper including a distal electrode surface, and a juncture between the proximal and distal electrode surface. The juncture is spaced further from the first tissue grasping feature compared to the proximal and distal end while the second jaw is in the partially closed position. The proximal and distal electrode surface deform to define a gap with the first tissue grasping feature while in the closed position.

Abstract: Provided are multispecific antibodies or antigen binding fragments thereof comprising at least one first antigen-binding region capable of binding specifically to pyroglutamate amyloid-?, a second antigen-binding region capable of binding specifically to transferrin receptor (TfR), and a third antigen-binding region capable of binding specifically to paired helical filament (PHF)-tau. Also provided are methods of treating or detecting a neurological disorder and/or delivering a therapeutic or diagnostic agent across the blood-brain barrier. Also described are nucleic acids encoding the antibodies, vectors comprising the nucleic acids, recombinant host cells comprising the nucleic acids and/or vectors, and methods of producing the multispecific antibodies or antigen binding fragments thereof.

Abstract: The present disclosure relates to systems, devices, and methods for controlling fluid flow within a cell processing system. In an embodiment, the present disclosure relates to a device having a rotor comprising one or more rollers configured to compress a first fluid conduit, a first lever arm defining a proximal portion and a distal portion, where the first lever arm comprises a first hinge at the proximal portion, and a second hinge in between the proximal portion and the distal portion, a spring coupled to the distal portion, and a second lever arm, where the first and second lever arms are aligned with the rotor and are configured to receive the first fluid conduit.

Abstract: A pectus excavatum treating apparatus or assembly having two pectus bars joined by a connecting member.

Abstract: A method of viewing a live image from a microscope through a camera lens of a first personal electronic device is described. The method includes receiving one or more optic powers of a microscope taking the live image entered into a first graphical user interface displayed on a screen of the first personal electronic device, and projecting a measurement tool on a second graphical user interface displayed on the screen of the first personal electronic device with units of measurement based on the entered optic powers. One or more non-transitory, computer-readable storage media and a computer or computer system are also described. Hardware designed to connect a personal electronic device such as a smartphone to a microscope for viewing of a live microscope image through the camera lens of the personal electronic device is also described.

Abstract: A cyclonic particle separator (126) may include a housing (130) including a cylindrical sidewall (132) having a plurality of flow entry ports (134). A mounting member (140) having a flow exit opening (160) at a second end (142) of the sidewall (132). At least one particle exit passage (176) in the housing (130). Each of the flow entry ports (134) includes a flow directing surface angled to direct a gas flow from upstream of the housing (130) to enter the housing (130) in a tangential direction relative to the cylindrical sidewall (132), causing a cyclone vortex. The cyclone vortex separates particles from the gas flow. The cylindrical sidewall (132) may have a first diameter (Dsep), and the flow exit opening (160) may have a second diameter (Dcool), where a difference between the first diameter (Dsep) and the second diameter (Dcool) is greater than 12.5 millimeters.

Abstract: A control module for residential environments, commercial environments, manufacturing environments, public buildings, and retail environments. Currently, configuring or reconfiguring systems for these environments is time consuming. It would be beneficial to provide arbitrarily configurable sensor and control modules and more particularly to intelligent arbitrarily configurable sensor and control modules and arrays of sensor and control modules allowing increased functionality, connectivity, intelligence, decision making, and communications within these systems. Provided is a module including a casing; one or more interfaces, each interface disposed at a predetermined position within a surface of the casing and supporting at least one of data communications and power; and one or more circuits coupled to the one or more interfaces.

Abstract: The invention provides an apparatus and method for holding vials and other containers for use in medical and other applications wherein hands-free access to vials and other containers is desired. The apparatus includes a clamp-like vial receiving portion having a pair of opposing jaws, including a first jaw having a pair of planar surfaces arranged at an angle, and a second jaw having a pair of opposing curved surfaces each in the form of a portion of a conical frustum with the curved surfaces being arranged at an angle. The planar and curved surfaces of the opposing jaws cooperate to stably hold vials and other containers of various circumference sizes.

Abstract: A dynamic occupancy grid determination method includes: obtaining, at an apparatus, at least one radar-based occupancy grid based on radar sensor measurements, each of the at least one radar-based occupancy grid comprising a plurality of first cells, each cell of the plurality of first cells having a corresponding first occupancy probability and first velocity; obtaining, at the apparatus, at least one camera-based occupancy grid based on camera measurements, each of the at least one camera-based occupancy grid comprising a plurality of second cells, each cell of the plurality of second cells having a corresponding second occupancy probability and second velocity; and determining, at the apparatus, a dynamic occupancy grid by analyzing the at least one radar-based occupancy grid and the at least one camera-based occupancy grid.

Abstract: Techniques are provided for utilizing a dynamic occupancy grid (DoG) for tracking objects proximate to an autonomous or semi-autonomous vehicle. An example method for generating an object track list in a vehicle includes obtaining sensor information from one or more sensors on the vehicle, determining a first set of object data based at least in part on the sensor information and an object recognition process, generating a dynamic grid based on an environment proximate to the vehicle based at least in part on the sensor information, determining a second set of object data based at least in part on the dynamic grid, and outputting the object track list based on a fusion of the first set of object data and the second set of object data.

Abstract: A matching computer system for electronically generating, matching, and providing online user profiles, and determining a trust score for a user based upon at least social media data and insurance data is provided. The matching computer system may be configured to register users within the matching computer system, receive consent from the users to capture the social media data, and collect the social media data and the insurance data from each registered user. The matching computer system may also be configured to retrieve the social media data and the insurance data associated with each registered user. The matching computer system may be further configured to determine a trust score for each registered user based upon each respective social media data and each respective insurance data. Each trust score represents a level of trustworthiness of the user.