Patents by Inventor Wolfgang Friess

Wolfgang Friess has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190219111
    Abstract: A method for the transmission and damping of a mean torque with a superposed alternating torque in an arrangement having an input and an output. The mean torque and superposed alternating torque are transmitted along a path from the input to the output. A slip arrangement is provided in the torque path between the input and the output for transmitting mean torque and superposed alternating torque and for generating a speed slip between an input speed and an output speed in the path. The slip arrangement provides a maximum of an external activation of the speed slip in the area of the maxima of at least one periodic oscillation component of the alternating component and provides a minimum of an external activation of the speed slip in the area of the minima of at least one periodic oscillation component of the alternating component.
    Type: Application
    Filed: May 29, 2017
    Publication date: July 18, 2019
    Inventors: Tobias HÖCHE, Tobias DIECKHOFF, Daniel LORENZ, Andreas ORLAMÜNDER, Ingrid HOFFELNER, Wolfgang GROSSPIETSCH, Steffen MATSCHAS, Johannes FRIESS, Christofer EBERT, Matthias KRAM, Dennis EGLER, Axel ROHM, Erwin WACK, Bernd UNSELD, Thomas Dögel, Matthias REISCH, Christoph SASSE, Mathais KOPP
  • Publication number: 20190195298
    Abstract: A method for transmission of and damping of a mean torque with a superposed alternating torque in a torque transmission arrangement for a powertrain of a motor vehicle having an input and an output. The mean torque with the superposed alternating torque is transmitted along a torque path from the input the output. The input rotates at an input speed and the output rotates at an output speed. A slip arrangement is provided in the torque path between the input and the output for generating a speed slip. The slip arrangement provides a maximum of an external activation of the speed slip in the area of a maxima of at least one periodic oscillation component of an alternating component and provides a minimum of an external activation of the speed slip in the area of a minima of at least one periodic oscillation component of the alternating component (new).
    Type: Application
    Filed: May 29, 2017
    Publication date: June 27, 2019
    Applicant: ZF FRIEDRICHSHAFEN AG
    Inventors: Tobias HÖCHE, Tobias DIECKHOFF, Daniel LORENZ, Andreas ORLAMÜNDER, Ingrid HOFFELNER, Wolfgang GROSSPIETSCH, Steffen MATSCHAS, Johannes FRIESS, Christofer EBERT, Matthias KRAM, Dennis EGLER, Axel ROHM, Erwin WACK, Bernd UNSELD, Thomas DÖGEL, Matthias REISCH, Lukas SPATH, Angelika EBERT
  • Publication number: 20190162255
    Abstract: A method for the transmission and damping of a mean torque with a superposed alternating torque having an input and an output. The mean and superposed alternating torque is transmitted along a torque path from the input to the output area. An input speed is a mean speed and a superposed alternating component. A slip arrangement is provided in the torque path between the input and the output for transmitting the mean and superposed alternating torque and generating a speed slip between an input speed and an output speed. The slip arrangement provides a maximum of an external activation of the speed slip in a area of the maxima of at least one periodic oscillation component of the alternating component and provides a minimum of an external activation of the speed slip in an area of the minima of at least one periodic oscillation component of the alternating component.
    Type: Application
    Filed: May 29, 2017
    Publication date: May 30, 2019
    Applicant: ZF FRIEDRICHSHAFEN AG
    Inventors: Tobias HÖCHE, Tobias DIECKHOFF, Daniel LORENZ, Andreas ORLAMÜNDER, Ingrid HOFFELNER, Wolfgang GROSSPIETSCH, Steffen MATSCHAS, Johannes FRIESS, Christofer EBERT, Matthias KRAM, Dennis EGLER, Axel ROHM, Erwin WACK, Bernd UNSELD, Thomas DÖGEL, Matthias REISCH, Lukas SPATH, Angelika EBERT
  • Patent number: 9956164
    Abstract: A veterinary pharmaceutical composition, including at least one active veterinary pharmaceutical substance which is selected among gonadorelin and gonadorelin analogs as well as salts of gonadorelin and of the gonadorelin analogs, is provided. The composition includes a liposome-free matrix which delays the release of the active veterinary pharmaceutical substance from the composition, which matrix includes a basic material which is selected from the group consisting of natural and synthetic triglycerides, vegetable oils, diacylpropanediols, diacylbutanediols and mixtures of these substances, the veterinary pharmaceutical composition including no biodegradable polymer.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: May 1, 2018
    Assignee: Veyx-Pharma GmbH
    Inventors: Wolfgang Zaremba, Johannes Kauffold, Wolfgang Friess, Kerstin Hoffmann, Yordanka Yordanova
  • Patent number: 9770420
    Abstract: A method for producing a polyglycerol nanogel is disclosed, the method comprising the following steps: Mixing an aqueous solution of first polyglycerol macromonomers, which are modified with a first reactive group, with an aqueous solution of second polyglycerol macromonomers, which are modified with a second reactive group, wherein the first reactive group and the second reactive group can react with each other forming a chemical bond; transferring the mixture into an organic non-solvent; and precipitation of a polyglycerol nanogel consisting of first polyglycerol macromonomers and second polyglycerol macromonomers which are covalently bound to each other. According to an aspect of the invention, the method is characterized in that the organic non-solvent is miscible with water and in that the method is carried out without adding surface-active substances.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: September 26, 2017
    Assignee: FREIE UNIVERSITÄT BERLIN
    Inventors: Rainer Haag, Dirk Steinhilber, Wolfgang Friess, Sarah Küchler, Madeleine Witting
  • Publication number: 20170189328
    Abstract: A veterinary pharmaceutical composition, including at least one active veterinary pharmaceutical substance which is selected among gonadorelin and gonadorelin analogs as well as salts of gonadorelin and of the gonadorelin analogs, is provided. The composition includes a liposome-free matrix which delays the release of the active veterinary pharmaceutical substance from the composition, which matrix includes a basic material which is selected from the group consisting of natural and synthetic triglycerides, vegetable oils, diacylpropanediols, diacylbutanediols and mixtures of these substances, the veterinary pharmaceutical composition including no biodegradable polymer.
    Type: Application
    Filed: April 16, 2015
    Publication date: July 6, 2017
    Inventors: Wolfgang ZAREMBA, Johannes KAUFFOLD, Wolfgang FRIESS, Kerstin HOFFMANN, Yordanka YORDANOVA
  • Patent number: 9500406
    Abstract: The invention provides a monitoring device (32) for a dryer (10) includes a means for sensing a physical parameter, such as temperature or strain, at a sensing locus within the dryer (10), for example at a vial (20). The sensing means comprises an optical sensing fiber (38) having at least one fiber Bragg grating (54). Moreover, the invention provides a dryer, in particular a freeze dryer (10), which is equipped with such monitoring device (32).
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: November 22, 2016
    Inventors: Wolfgang Friess, Manfred Resch, Michael Wiggenhorn
  • Publication number: 20150283094
    Abstract: A method for producing a polyglycerol nanogel is disclosed, the method comprising the following steps: Mixing an aqueous solution of first polyglycerol macromonomers, which are modified with a first reactive group, with an aqueous solution of second polyglycerol macromonomers, which are modified with a second reactive group, wherein the first reactive group and the second reactive group can react with each other forming a chemical bond; transferring the mixture into an organic non-solvent; and precipitation of a polyglycerol nanogel consisting of first polyglycerol macromonomers and second polyglycerol macromonomers which are covalently bound to each other. According to an aspect of the invention, the method is characterized in that the organic non-solvent is miscible with water and in that the method is carried out without adding surface-active substances.
    Type: Application
    Filed: September 5, 2013
    Publication date: October 8, 2015
    Applicant: FREIE UNIVERSITÄT BERLIN
    Inventors: Rainer Haag, Dirk Steinhilber, Wolfgang Friess, Sarah Hedtrich (Born Küchler), Madeleine Witting
  • Publication number: 20150101208
    Abstract: The invention provides a monitoring device (32) for a dryer (10) includes a means for sensing a physical parameter, such as temperature or strain, at a sensing locus within the dryer (10), for example at a vial (20). The sensing means comprises an optical sensing fiber (38) having at least one fiber Bragg grating (54). Moreover, the invention provides a dryer, in particular a freeze dryer (10), which is equipped with such monitoring device (32).
    Type: Application
    Filed: December 19, 2014
    Publication date: April 16, 2015
    Inventors: Wolfgang Friess, Manfred Resch, Michael Wiggenhorn
  • Patent number: 8919007
    Abstract: The invention provides a monitoring device (32) for a dryer (10) includes a means for sensing a physical parameter, such as temperature or strain, at a sensing locus within the dryer (10), for example at a vial (20). The sensing means comprises an optical sensing fiber (38) having at least one fiber Bragg grating (54). Moreover, the invention provides a dryer, in particular a freeze dryer (10), which is equipped with such monitoring device (32).
    Type: Grant
    Filed: December 29, 2009
    Date of Patent: December 30, 2014
    Inventors: Wolfgang Friess, Manfred Resch, Michael Wiggenhorn
  • Patent number: 8829072
    Abstract: The invention provides a polymer based material comprising a water binding agent present in an amount sufficient to chemically and/or physically absorb and/or adsorb water to prevent degradation of the polymer. The invention also provides a polymer based material comprising a plasticizer or organic solvent as well as a multi-component material or composite including materials encompassing a second polymer and/or an active agent. The invention further provides a pharmaceutical composition comprising the aforesaid polymer based material, which can be used for treatment of bone, cartilage and/or periodontal defects.
    Type: Grant
    Filed: January 11, 2013
    Date of Patent: September 9, 2014
    Assignee: Scil Technology GmbH
    Inventors: Wolfgang Friess, Klaus Hellerbrand, Samuel Herberg, Cornelius Pompe, Andreas Schuetz, Michael Siedler
  • Patent number: 8372895
    Abstract: The present invention relates to a polymer based material comprising a water binding agent, whereas the water binding agent is present in an amount sufficient to chemically and/or physically absorb and/or adsorb water to prevent degradation of the polymer. It also relates to a polymer based material which comprises a plasticizer or organic solvent as well as a multi-component material or composite including materials encompassing a second polymer and/or an active agent. Furthermore it relates to a method for manufacturing the polymer comprising material and use of the material for the preparation of a pharmaceutical composition to be used for treatment of bone, cartilage and/or periodontal defects. The invention also encompasses a kit using the polymeric material.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: February 12, 2013
    Assignee: Scil Technology GmbH
    Inventors: Wolfgang Friess, Klaus Hellerbrand, Samuel Herberg, Cornelius Pompe, Andreas Schuetz, Michael Siedler
  • Publication number: 20120004170
    Abstract: Disclosed are methods of making bioactive BMP-2 microparticles and methods of using the microparticles.
    Type: Application
    Filed: January 26, 2011
    Publication date: January 5, 2012
    Inventors: Susan J. Sofia, Daniel Schwartz, Wolfgang Friess
  • Publication number: 20110247234
    Abstract: The invention provides a monitoring device (32) for a dryer (10) includes a means for sensing a physical parameter, such as temperature or strain, at a sensing locus within the dryer (10), for example at a vial (20). The sensing means comprises an optical sensing fiber (38) having at least one fiber Bragg grating (54). Moreover, the invention provides a dryer, in particular a freeze dryer (10), which is equipped with such monitoring device (32).
    Type: Application
    Filed: December 29, 2009
    Publication date: October 13, 2011
    Inventors: Wolfgang Friess, Manfred Resch, Michael Wiggenhorn
  • Patent number: 7897174
    Abstract: Disclosed are methods of making BMP-2 microparticles and methods of using the microparticles. These microparticles are prepared, for example, by mixing a solution containing BMP-2 with a second solution whose ionic concentration and pH results in the precipitation of the BMP-2.
    Type: Grant
    Filed: February 10, 2003
    Date of Patent: March 1, 2011
    Assignees: University of Erlangen-Nurnberg, Wyeth Inc.
    Inventors: Susan J. Sofia, Daniel Schwartz, Wolfgang Friess
  • Patent number: 7879976
    Abstract: The invention relates to a method for stabilizing an aqueous protein solution against exogenous stress and to the use of a container for stabilizing an aqueous protein solution.
    Type: Grant
    Filed: April 25, 2008
    Date of Patent: February 1, 2011
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Wolfgang Friess, Sylvia Kiese, Hanns-Christian Mahler, Astrid Pappenberger
  • Patent number: 7727962
    Abstract: The present invention concerns powders containing a pharmaceutical active substance and a combination of excipients comprising at least one 1,4 O-linked saccharose derivative selected from the compounds: 1,4 O-linked D-Gal-saccharose (lactosucrose), 1,4 O-linked D-Glu-saccharose (glucosyl sucrose), or 1,4 O-linked Glu-Glu-saccharose (maltosyl sucrose) in combination with at least one further excipient. The other excipient is preferably an amino acid, a peptide and/or a mono-, di- and/or oligosaccharide, wherein the oligosaccharide may be a second 1,4 O-linked saccharose derivative, provided that this is different from the first.
    Type: Grant
    Filed: May 2, 2005
    Date of Patent: June 1, 2010
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Stefan Bassarab, Karoline Bechtold-Peters, Richard Fuhrherr, Wolfgang Friess, Patrick Garidel, Torsten Schultz-Fademrecht
  • Patent number: 7723306
    Abstract: The present invention relates to a spray-dried powder and method for its manufacture. A spray dried powder containing a pharmaceutical active substance and one or more 1,4 O-linked saccharose derivatives chosen from the compounds: 1,4 O-linked D-gal-saccharose (lactosucrose), 1,4 O-linked D-glu-saccharose (glucosyl sucrose) or 1,4 O-linked glu-glu-saccharose (maltosyl sucrose). Preferred combinations are such that they contain glucosyl and maltosyl sucrose.
    Type: Grant
    Filed: May 2, 2005
    Date of Patent: May 25, 2010
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Stefan Bassarab, Karoline Bechtold-Peters, Richard Fuhrherr, Wolfgang Friess, Patrick Garidel, Torsten Schultz-Fademrecht
  • Patent number: 7611709
    Abstract: Disclosed are applications of oligosaccharides/oligosaccharide mixtures for the production and stabilization of pharmaceutical compositions, chiefly powders, that contain antibodies or antibody derivatives as pharmaceutical active substance. The production of powders is accomplished through spray drying or freeze drying. Also disclosed are the corresponding antibody-containing powders as well as processes for their production.
    Type: Grant
    Filed: May 2, 2005
    Date of Patent: November 3, 2009
    Assignee: Boehringer Ingelheim Pharma GmbH and Co. KG
    Inventors: Stefan Bassarab, Karoline Bechtold-Peters, Richard Fuhrherr, Wolfgang Friess, Patrick Garidel, Torsten Schultz-Fademrecht
  • Publication number: 20090209660
    Abstract: The present invention relates to a polymer based material comprising a water binding agent, whereas the water binding agent is present in an amount sufficient to chemically and/or physically absorb and/or adsorb water to prevent degradation of the polymer. It also relates to a polymer based material which comprises a plasticizer or organic solvent as well as a multi-component material or composite including materials encompassing a second polymer and/or an active agent. Furthermore it relates to a method for manufacturing the polymer comprising material and use of the material for the preparation of a pharmaceutical composition to be used for treatment of bone, cartilage and/or periodontal defects. The invention also encompasses a kit using the polymeric material.
    Type: Application
    Filed: June 28, 2007
    Publication date: August 20, 2009
    Applicant: Scil Technology GmbH
    Inventors: Wolfgang Friess, Klaus Hellerbrand, Samuel Herberg, Cornelius Pompe, Andreas Schuetz, Michael Siedler