Patents by Inventor Wolfgang Haap

Wolfgang Haap has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7078550
    Abstract: There are described silanyl phenols and naphthols of formula (1a) or (1b), wherein R1 is hydrogen; halogen; hydroxy; C1–C20alkyl; C3–C12cycloalkyl; C1–C20alkoxy; trifluoromethyl; pentafluoroethyl; mono- or di-C1–C5alkylamino; hydroxy-C1–C5alkyl; or phenyl, phenyl-C1–C20alkyl, phenoxy, phenyl-C1–C20alkoxy, naphthyl or naphthyl-C1–C20alkyl each unsubstituted or substituted by C1–C5alkyl, C3–C12cycloalkyl, C1–C5alkoxy, C3–C12cycloalkoxy, halogen, oxo, carboxy, carboxy-C1–C7alkyl ester, carboxy-C3–C12cycloalkyl ester, cyano, trifluoromethyl, pentafluoroethyl, amino, N,N-mono- or di-C1–C20alkylamino or by nitro; R2, R3 and R4 are each independently of the others hydrogen; C1–C20alkyl; or C3–C12-cycloalkyl; R5, R6 and R7 are each independently of the others C1–C20alkyl, C5–C10aryl, C1–C20alkoxy, phenyl-C1–C20alkyl, phenyl-C1–C20alkoxy, C2–C5alkenyl, —O—Si—(C1–C5alkyl)3; or O—Si—(C1–C5alkyl)2-O—Si(C1–C5alkyl)3 and n is 0 or 1.
    Type: Grant
    Filed: January 10, 2002
    Date of Patent: July 18, 2006
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Werner Hölzl, Wolfgang Haap, Jürgen Koppold
  • Publication number: 20060142362
    Abstract: The invention is concerned with novel heteroarylacetamides of formula (I) Rd—C(O)—N(Re)—Rc—CH2—C(O)—N(Ra)(Rb) ??(I) wherein Ra to Re are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the coagulation factor Xa and can be used as medicaments.
    Type: Application
    Filed: December 13, 2005
    Publication date: June 29, 2006
    Inventors: Markus Boehringer, Katrin Zbinden, Wolfgang Haap, Hans Hilpert, Narendra Panday, Fabienne Ricklin
  • Publication number: 20060106016
    Abstract: The invention is concerned with novel dicarboxamide derivatives of formula (I) wherein A, B, Rc, D and E are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the coagulation factor Xa and can be used as medicaments.
    Type: Application
    Filed: October 31, 2005
    Publication date: May 18, 2006
    Inventors: Markus Boehringer, Katrin Zbinden, Wolfgang Haap, Hans Hilpert, Jacques Himber, Roland Humm, Hans Iding, Dietmar Knopp, Narendra Panday, Fabienne Ricklin, Christoph Stahl
  • Patent number: 7015228
    Abstract: Compounds of formula wherein R1 and R2 are each independently of the other hydrogen; unsubstituted or mono- or poly-halo-substituted C1–C20alkyl, C1–C20alkoxy, C2–C20alkenyl, C2–C20alkynyl, C3–C18cycloalkyl, C3–C7cycloalkyl-C1–C20alkyl; hydroxy; C1–C6alkoxy-C1–C20alkyl; carboxy; C1–C6alkyloxycarbonyl; cyano; mono- or di-C1–C20alkylamino; C1–C6alkylamino-C1–C20alkyl; halogen; phenyl; unsubstituted or C1–C5alkyl-, halo- or hydroxy-substituted phenyl-C1–C20alkyl, phenoxy or phenyl-C1–C20alkoxy; or R1 and R2 form a polymethylene chain of formula —(CH2)m— wherein m=2–12; R3 is unsubstituted C7–C20alkyl; or amino-, hydroxy-, carboxy- or C1–C6alkyloxycarbonyl-substituted C2–C20alkyl; C8–C18cycloalkyl; C8–C20alkenyl; C8–C20alkynyl; C3–C7cycloalkyl-C8–C20alkyl; C1–C4alkoxy-C8–C20alkyl; R7R8N—C7–C20alkyl; phenyl; phenyl-C1–C4alkyl; or phenyl-C1–C4alkoxy; R4 is hydrogen; unsubstituted or C1–C5alkyl-, halo- or hydroxy-substituted C1–C20alkyl, C2–C20alkenyl, C2–C20alkynyl, C3–C20cycloalkyl, C3–C7cycloalkyl-C1–C20alky
    Type: Grant
    Filed: April 17, 2002
    Date of Patent: March 21, 2006
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Wolfgang Haap, Werner Hölzl, Karin Petzold
  • Patent number: 6967215
    Abstract: Tetrahydrocarbazoles of formula where Q is —SO2—; —O—; or —(CO)—; X is —(CH)—; or —N—; m is from 1 to 3; t is 0 or 1 and the remaining substituents are as defined herein, are useful as antimicrobial active ingredients.
    Type: Grant
    Filed: September 11, 2001
    Date of Patent: November 22, 2005
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Wolfgang Haap, Andreas Mehlin, Karin Petzold, Dietmar Ochs, Werner Hölzl
  • Publication number: 20050215599
    Abstract: The invention is concerned with novel pyrrolidine-3,4-dicarboxamide derivatives of formula (I) wherein R1 to R9 and X are as defined in the description and in the claims, as well as physiologically acceptable salts thereof.
    Type: Application
    Filed: March 9, 2005
    Publication date: September 29, 2005
    Inventors: Lilli Anselm, Katrin Zbinden, Wolfgang Haap, Jacques Himber, Christoph Stahl, Stefan Thomi
  • Publication number: 20050143387
    Abstract: Use of 4-aminopyrimidines of formula (1), wherein R1, R2, R3, R4 and R5 are as described in the description in the antimicrobial treatment of surfaces.
    Type: Application
    Filed: March 10, 2003
    Publication date: June 30, 2005
    Inventors: Sophie Marquais-Bienewald, Werner Holzl, Wolfgang Haap, Andrea Preuss, Andreas Mehlin
  • Publication number: 20050143373
    Abstract: The present invention relates to compounds of the general formula and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases such as obesity by selective modulation of CB1 receptors.
    Type: Application
    Filed: February 22, 2005
    Publication date: June 30, 2005
    Inventors: Alexander Alanine, Konrad Bleicher, Wolfgang Guba, Wolfgang Haap, Dagmar Kube, Thomas Luebbers, Jean-Marc Plancher, Olivier Roche, Mark Rogers-Evans, Gisbert Schneider, Jochen Zuegge
  • Patent number: 6900227
    Abstract: The present invention relates to compounds of the general formula and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases such as obesity by selective modulation of CB1 receptors.
    Type: Grant
    Filed: July 24, 2003
    Date of Patent: May 31, 2005
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alexander Alanine, Konrad Bleicher, Wolfgang Guba, Wolfgang Haap, Dagmar Kube, Thomas Luebbers, Jean-Marc Plancher, Olivier Roche, Mark Rogers-Evans, Gisbert Schneider, Jochen Zuegge
  • Patent number: 6846492
    Abstract: The use of compounds of formula (1) is described, in which compounds R1, R2 and R3 are each independently of the others hydrogen; C1-C20alkyl; C3-C7cycloalkyl; C2-C20alkenyl; C4-C7cycloalkenyl; C2-C20alkynyl, C4-C7cycloalkynyl; or unsubstituted or C1-C5alkyl-, C3-C7cylcoalkyl-, C1-C5alkoxyl-, C3-C7cycloakoxy-, halo-, oxo-, carboxy-, carboxy-C1-C7alkyl ester-, carboxy-C3-C7cylcloalkyl ester-, cyano-, trifluoromethyl-, pentafluoroethyl-, amino-, N,N-mono- or di-C1-C20alkylamino- or nitro-substituted phenyl-C1-C5alkyl, naphthyl-C1-C5alkyl, phenylcarbonyl-C1-C5alkyl, naphthylcarbonyl-C1-C5alkyl, pyrrolylalkyl, furanylalkyl, thiophenylalkyl, pyrazolylalkyl, imidazolylalkyl, oxazolylalkyl, thiazolylalkyl, isoxazolylalkyl, isothiazolylalkyl, 1,2,3-triazolylalkyl, 1,2,4-triazolylalkyl, 1,2,3-oxadiazolylalkyl, 1,3,4-oxadiazolylalkyl, 1,2,3-thiadiazolylalkyl, 1,3,4-thiadiazolylalkyl, indolylalkyl, pyridylalkyl, pyridazinylalkyl, pyrimidinylalkyl, pyridazinylalkyl, quinolinylalkyl, isoquinolinylalkyl, pyrrolyl, furanyl,
    Type: Grant
    Filed: February 13, 2001
    Date of Patent: January 25, 2005
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Wolfgang Haap, Werner Hölzl, Dietmar Ochs, Karin Petzold, Marcel Schnyder
  • Patent number: 6814960
    Abstract: The use of hydroxystilbene compounds of formula wherein A is a radical of formula  or a radical of formula  and R1, R2, R3, R4 and R5 are each independently of the others hydrogen, halogen, hydroxy, C1-C16alkyl, C1-C16alkoxy, phenyl; C1-C3phenylalkyl; C6-C10aryloxy, amino, mono-C1-C5alkylamino, di-C1-C5alkylamino, or —NO2; as microbicidal active ingredients is described. The compounds exhibit a pronounced action against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and moulds. They are therefore suitable for the antimicrobial treatment, especially the preservation and disinfection, of surfaces.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: November 9, 2004
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Werner Hölzl, Dietmar Ochs, Wolfgang Haap, Karin Puchtler, Marc I Schnyder
  • Publication number: 20040186174
    Abstract: The present invention relates to the use of hydroxydiphenyl ether compounds as antimicrobially active substances, to certain new compounds of this type and to processes for the preparation of these compounds.
    Type: Application
    Filed: April 2, 2004
    Publication date: September 23, 2004
    Inventors: Werner Holzl, Wolfgang Haap, Dietmar Ochs, Karin Puchtler, Marcel Schnyder, Surendra Umesh Kulkarni, Arakali Srinivasarao Radhakrishna, Mangesh Shivram Sawant, Asawari Bhikaji Mahtre
  • Publication number: 20040147572
    Abstract: The present invention relates to compounds of formula (I) 1
    Type: Application
    Filed: December 22, 2003
    Publication date: July 29, 2004
    Inventors: Wolfgang Guba, Wolfgang Haap, Hans Peter Marty, Robert Narquizian
  • Publication number: 20040142922
    Abstract: The present invention relates to compounds of the general formula 1
    Type: Application
    Filed: July 24, 2003
    Publication date: July 22, 2004
    Inventors: Alexander Alanine, Konrad Bleicher, Wolfgang Guba, Wolfgang Haap, Dagmar Kube, Thomas Luebbers, Jean-Marc Plancher, Olivier Roche, Mark Rogers-Evans, Gisbert Schneider, Jochen Zuegge
  • Patent number: 6759423
    Abstract: The present invention relates to the use of 4-hydroxyisothiazole compounds as antimicrobially active substances, certain new 4-hydroxyisothiazole compounds and a process for their preparation.
    Type: Grant
    Filed: October 3, 2001
    Date of Patent: July 6, 2004
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Werner Hölzl, Wolfgang Haap, Dietmar Ochs, Karin Puchtler, Marcel Schnyder, Dinesh Narendra Rele, Sitaram Pal, Asawari Bhikaji Mahtre, Surendra Umesh Kulkarni, Arakali Srinivasarao Radhakrishna
  • Patent number: 6743940
    Abstract: There are described 4-aminobut-2-ynecarboxylic acid derivatives of formula wherein R1 and R2 are each independently of the other hydrogen, C1-C20alkyl; C3-C12cycloalkyl; unsubstituted or C1-C5alkyl-, C3-C12cycloalkyl-, C1-C5alkoxy-, C3-C12cycloalkoxy-, halo-, oxo-, carboxy-, carboxy-C1-C7alkyl ester-, carboxy-C3-C12cycloalkyl ester-, cyano-, trifluoromethyl-, pentafluoroethyl-, amino-, N,N-mono- or di-C1-C20alkylamino- or nitro-substituted phenyl, phenyl-C1-C5alkyl, naphthyl and naphthyl-C1-C5alkyl; and R3 is C1-C20alkyl; C3-C12cycloalkyl. The compounds exhibit a pronounced activity against gram-positive and gram-negative bacteria, and also against yeasts and moulds.
    Type: Grant
    Filed: December 13, 2001
    Date of Patent: June 1, 2004
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Werner Hölzl, Wolfgang Haap, Jürgen Koppold, Dietmar Ochs, Karin Petzold, Marcel Schnyder
  • Publication number: 20040097535
    Abstract: There are described tetrahydrocarbazoles of formula (1) or (2). The compounds are suitable as antimicrobial active ingredients.
    Type: Application
    Filed: March 13, 2003
    Publication date: May 20, 2004
    Inventors: Wolfgang Haap, Andreas Mehlin, Karin Petzold, Dietmar Ochs, Werner Holzl
  • Publication number: 20040058891
    Abstract: There are described silanyl phenols and naphthols of formula (1a) or (1b), wherein R1 is hydrogen; halogen; hydroxy; C1-C20alkyl; C3-C12cycloalkyl; C1-C20alkoxy; trifluoromethyl; pentafluoroethyl; mono- or di-C1-C5alkylamino; hydroxy-C1-C5alkyl; or phenyl, phenyl-C1C20alkyl, phenoxy, phenyl-C1-C20alkoxy, naphthyl or naphthyl-C1-C20alkyl each unsubstituted or substituted by C1-C5alkyl, C3-C12cycloalkyl, C1-C5alkoxy, C3-C12cycloalkoxy, halogen, oxo, carboxy, carboxy-C1-C7alkyl ester, carboxy-C3-C12cycloalkyl ester, cyano, trifluoromethyl, pentafluoroethyl, amino, N,N-mono- or di-C1-C20alkylamino or by nitro; R2, R3 and R4 are each independently of the others hydrogen; C1-C20alkyl; or C3-C12-Cycloalkyl; R5, R6 and R7 are each independently of the others C1-C20alkyl, C5-C10aryl, C1-C20alkoxy, phenyl-C1-C20alkyl, phenyl-C1-C20alkoxy, C2-C5alkenyl, —O—Si—(C1-C5alkyl)3; or O—Si—(C1-C5alkyl)2-O—Si(C1-C5alkyl)3 and n is 0 or 1.
    Type: Application
    Filed: July 15, 2003
    Publication date: March 25, 2004
    Inventors: Werner Holzl, Wolfgang Haap, Jurgen Koppold
  • Publication number: 20040006061
    Abstract: There are described alkoxybenzylamines corresponding to formula 1
    Type: Application
    Filed: October 2, 2002
    Publication date: January 8, 2004
    Inventors: Wolfgang Haap, Werner Holzl, Karin Petzold
  • Publication number: 20030207884
    Abstract: The use of compounds of formula (1) is described, in which compounds R1, R2 and R3 are each independently of the others hydrogen; C1-C20alkyl; C3-C7cycloalkyl; C2-C20alkenyl; C4-C7cycloalkenyl; C2-C20alkynyl, C4-C7cycloalkynyl; or unsubstituted or C1-C5alkyl-, C3-C7cylcoalkyl-, C1-C5alkoxyl-, C3-C7cycloakoxy-, halo-, oxo-, carboxy-, carboxy-C1-C7alkyl ester-, carboxy-C3-C7cylcloalkyl ester-, cyano-, trifluoromethyl-, pentafluoroethyl-, amino-, N,N-mono- or di-C1-C20alkylamino- or nitro-substituted phenyl-C1-C5alkyl, naphthyl-C1-C5alkyl, phenylcarbonyl-C1-C5alkyl, naphthylcarbonyl-C1-C5alkyl, pyrrolylalkyl, furanylalkyl, thiophenylalkyl, pyrazolylalkyl, imidazolylalkyl, oxazolylalkyl, thiazolylalkyl, isoxazolylalkyl, isothiazolylalkyl, 1,2,3-triazolylalkyl, 1,2,4-triazolylalkyl, 1,2,3-oxadiazolylalkyl, 1,3,4-oxadiazolylalkyl, 1,2,3-thiadiazolylalkyl, 1,3,4-thiadiazolylalkyl, indolylalkyl, pyridylalkyl, pyridazinylalkyl, pyrimidinylalkyl, pyridazinylalkyl, quinolinylalkyl, isoquinolinylalkyl, pyrrolyl, furanyl,
    Type: Application
    Filed: August 21, 2002
    Publication date: November 6, 2003
    Inventors: Wolfgang Haap, Werner Holzl, Dietmar Ochs, Karin Petzold, Marcel Schnyder