Patents by Inventor Wolfgang Petrich
Wolfgang Petrich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11224365Abstract: Disclosed is a fully implantable sensor for detecting at least one analyte in a sample of body fluid. The sensor has a measurement chamber plate that receives the sample of bodily fluid and a quantum cascade laser illumination source that generates an illumination light beam in the spectral range and transmits it to the measurement chamber plate. The illumination light beam at least partially illuminates the measurement chamber plate and the measurement chamber plate generates a reflection light beam in response to the illumination by the illumination light beam. The reflection light beam at least partially illuminates the sample of body fluid within the measurement chamber plate. An optical detector detects at least one property of the reflection light beam and generates a sensor signal dependent on the presence of the analyte. A controlled evaluates the sensor signal. A method using an inventive fully implantable sensor is also disclosed.Type: GrantFiled: July 18, 2019Date of Patent: January 18, 2022Assignee: Roche Diabetes Care, Inc.Inventors: Frank Deck, Hans List, Wolfgang Petrich, Niels Kroeger-Lui, Katharina Haase
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Patent number: 11060978Abstract: Methods are provided for deriving/determining an analyte concentration that include recording measurement values during a time development indicating a progress of a detection reaction of at least one test substance and a body fluid sample and providing at least one measurement curve F(t) containing the measurement values, where the detection reaction is known to be influenced by the analyte concentration and at least one disturbance variable Y. The methods also include deriving an end value of the measurement curve to form a first variable x1, and deriving at least one fit parameter by taking into account an exponential characteristic of the measurement curve, and where the fit parameter forms at least one second variable x2. The methods further include deriving/determining the analyte concentration by using at least one multivariate evaluation algorithm adapted to combine x1 and x2. Also provided are computer programs and devices that incorporate the same.Type: GrantFiled: June 19, 2015Date of Patent: July 13, 2021Assignee: Roche Diabetes Care, Inc.Inventors: Christian Ringemann, Markus Plum, Wolfgang Petrich, Timo Ottenstein
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Publication number: 20210118570Abstract: The disclosure relates to a method for screening a subject for the risk of chronic kidney disease (CKD), comprising: receiving marker data indicative for a plurality of marker parameters for a subject, such plurality of marker parameters indicating, for the subject for a measurement period, an age value, a sample level of creatinine, and a sample level of albumin; and determining a risk factor indicative of the risk of suffering CKD for the subject from the plurality of marker parameters, wherein the determining comprises: weighting the age value higher than the sample level of albumin, and weighting the sample level of creatinine higher than the sample level of albumin. Further, a computer-implemented method for screening a subject and a method for screening a subject for the risk of chronic kidney disease (CKD) are provided.Type: ApplicationFiled: March 22, 2019Publication date: April 22, 2021Applicant: Roche Diabetes Care, Inc.Inventors: Wolfgang Petrich, Tony Huschto, Bernd Schneidinger, Stefan Ravizza, Alexander Buesser
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Patent number: 10984892Abstract: Methods are provided for detecting an analyte concentration/presence in a body fluid sample that include providing a set of at least two different evaluation rules, each evaluation rule adapted to derive a set characteristic values from an optical measurement curve, where at least one first characteristic value is derived from at least one first evaluation rule and at least one second characteristic value is derived from at least one second evaluation rule. The methods also include performing at least one multivariate analysis of the at least one first and second characteristic values by using at least one predetermined multivariate evaluation algorithm to derive at least one estimate value for at least one target variable Y of the state variables. The methods also include determining at least one analyte concentration by using the at least one target variable Y. Also provided are computer programs and devices that incorporate the same.Type: GrantFiled: July 3, 2019Date of Patent: April 20, 2021Inventors: Simon Aigner, Gabriele Chemnitius, Carina Horn, Bernd Limburg, Timo Ottenstein, Wolfgang Petrich, Markus Plum, Christian Ringemann, Markus Serr
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Patent number: 10724943Abstract: A device is proposed for detecting at least one analyte in a bodily fluid. The device comprises at least one test element with at least one two-dimensional evaluation region. The device furthermore comprises at least one spatially resolving optical detector having a plurality of pixels. The detector is designed to image at least part of the test element onto an image region. In the process, at least part of the evaluation region is imaged onto an evaluation image region. The detector is matched to the test element such that a predetermined minimum number of pixels is provided for each dimension within the evaluation image region. The pixels are arranged in a two-dimensional matrix arrangement. The matrix arrangement has pixel rows and pixel columns, wherein the pixel rows are arranged substantially parallel to a longitudinal direction of the evaluation region and/or of the evaluation image region.Type: GrantFiled: July 5, 2018Date of Patent: July 28, 2020Assignee: Roche Diabetes Care, Inc.Inventors: Wolfgang Petrich, Frank Weidner
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Publication number: 20200158655Abstract: Methods are provided for deriving/determining an analyte concentration that include recording measurement values during a time development indicating a progress of a detection reaction of at least one test substance and a body fluid sample and providing at least one measurement curve F(t) containing the measurement values, where the detection reaction is known to be influenced by the analyte concentration and at least one disturbance variable Y. The methods also include deriving an end value of the measurement curve to form a first variable x1, and deriving at least one fit parameter by taking into account an exponential characteristic of the measurement curve, and where the fit parameter forms at least one second variable x2. The methods further include deriving/determining the analyte concentration by using at least one multivariate evaluation algorithm adapted to combine x1 and x2. Also provided are computer programs and devices that incorporate the same.Type: ApplicationFiled: December 20, 2019Publication date: May 21, 2020Inventors: Christian Ringemann, Markus Plum, Wolfgang Petrich, Timo Ottenstein
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Publication number: 20200054258Abstract: A medical system, an analyte measurement device, a medication device and a method for transcutaneously inserting an insertable element into a body tissue are disclosed. The medical system comprises: at least one electronics unit having at least one electronics component; at least one adhesive surface for attachment of the electronics unit to a skin site of a host; at least one first subsystem configured for being at least partially inserted into the host; at least one second subsystem, wherein the second subsystem comprises at least one secondary sensor, wherein the first subsystem and the second subsystem are operably connectable to the electronics unit, wherein the second subsystem is physically attachable to the medical system.Type: ApplicationFiled: October 10, 2019Publication date: February 20, 2020Applicant: Roche Diabetes Care, Inc.Inventors: Emily Elise Gill, Wolfgang Petrich, Valerie Winckler-Desprez, Uwe Hensel
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Publication number: 20190369017Abstract: A method of evaluating the quality state (such as a fixation status) of a cellular sample is provided. A MIR spectrum (220) of the sample is obtained, and a classification (211) or quantification (231) algorithm is applied to the MIR spectrum to identify features (221) indicative of the quality state and/or to classify the sample. The quality state may then be used to determine whether the sample is appropriate for an analytical method and/or whether remedial processing (such as further fixation) is appropriate.Type: ApplicationFiled: April 27, 2018Publication date: December 5, 2019Inventors: Daniel Bauer, David Chafin, Niels Kroeger-Lui, Michael Otter, Wolfgang Petrich
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Publication number: 20190336050Abstract: Disclosed is a fully implantable sensor for detecting at least one analyte in a sample of body fluid. The sensor has a measurement chamber plate that receives the sample of bodily fluid and a quantum cascade laser illumination source that generates an illumination light beam in the spectral range and transmits it to the measurement chamber plate. The illumination light beam at least partially illuminates the measurement chamber plate and the measurement chamber plate generates a reflection light beam in response to the illumination by the illumination light beam. The reflection light beam at least partially illuminates the sample of body fluid within the measurement chamber plate. An optical detector detects at least one property of the reflection light beam and generates a sensor signal dependent on the presence of the analyte. A controlled evaluates the sensor signal. A method using an inventive fully implantable sensor is also disclosed.Type: ApplicationFiled: July 18, 2019Publication date: November 7, 2019Inventors: Frank Deck, Hans List, Wolfgang Petrich, Niels Kroeger-Lui, Katharina Haase
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Publication number: 20190325992Abstract: Methods are provided for detecting an analyte concentration/presence in a body fluid sample that include providing a set of at least two different evaluation rules, each evaluation rule adapted to derive a set characteristic values from an optical measurement curve, where at least one first characteristic value is derived from at least one first evaluation rule and at least one second characteristic value is derived from at least one second evaluation rule. The methods also include performing at least one multivariate analysis of the at least one first and second characteristic values by using at least one predetermined multivariate evaluation algorithm to derive at least one estimate value for at least one target variable Y of the state variables. The methods also include determining at least one analyte concentration by using the at least one target variable Y. Also provided are computer programs and devices that incorporate the same.Type: ApplicationFiled: July 3, 2019Publication date: October 24, 2019Inventors: Simon Aigner, Gabriele Chemnitius, Carina Horn, Bernd Limburg, Timo Ottenstein, Wolfgang Petrich, Markus Plum, Christian Ringemann, Markus Serr
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Publication number: 20180313746Abstract: A device is proposed for detecting at least one analyte in a bodily fluid. The device comprises at least one test element with at least one two-dimensional evaluation region. The device furthermore comprises at least one spatially resolving optical detector having a plurality of pixels. The detector is designed to image at least part of the test element onto an image region. In the process, at least part of the evaluation region is imaged onto an evaluation image region. The detector is matched to the test element such that a predetermined minimum number of pixels is provided for each dimension within the evaluation image region. The pixels are arranged in a two-dimensional matrix arrangement. The matrix arrangement has pixel rows and pixel columns, wherein the pixel rows are arranged substantially parallel to a longitudinal direction of the evaluation region and/or of the evaluation image region.Type: ApplicationFiled: July 5, 2018Publication date: November 1, 2018Inventors: Wolfgang Petrich, Frank Weidner
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Patent number: 10031067Abstract: A device is proposed for detecting at least one analyte in a bodily fluid. The device comprises at least one test element with at least one two-dimensional evaluation region. The device furthermore comprises at least one spatially resolving optical detector having a plurality of pixels. The detector is designed to image at least part of the test element onto an image region. In the process, at least part of the evaluation region is imaged onto an evaluation image region. The detector is matched to the test element such that a predetermined minimum number of pixels is provided for each dimension within the evaluation image region. The pixels are arranged in a two-dimensional matrix arrangement. The matrix arrangement has pixel rows and pixel columns, wherein the pixel rows are arranged substantially parallel to a longitudinal direction of the evaluation region and/or of the evaluation image region.Type: GrantFiled: November 25, 2015Date of Patent: July 24, 2018Assignee: Roche Diabetes Care, Inc.Inventors: Wolfgang Petrich, Frank Weidner
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Patent number: 9796746Abstract: The invention also relates to compounds, which are useful for intra-molecular fluorescence resonance energy transfer (FRET), comprising the oxidized form of a carbaNADH-based first fluorophore and a second fluorophore that is excitable at a wave-length of between 445 to 540 nm and that has an emission maximum of greater than 560 nm, and methods, kits and compositions related thereto.Type: GrantFiled: December 4, 2015Date of Patent: October 24, 2017Assignee: Roche Diagnostics Operations, Inc.Inventors: Dieter Heindl, Joachim Hoenes, Carina Horn, Thomas Meier, Wolfgang Petrich
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Patent number: 9611504Abstract: An analytical apparatus is disclosed for detecting at least one analyte in a sample, where in an analyte measurement at least an electrical or optical property changeable by presence of the analyte at least one test chemical of a test element is recorded, and where the analytical apparatus also can perform at least one quality measurement on the at least one test chemical such as an intrinsic luminescence, which is recorded and from the intrinsic luminescence a conclusion is drawn on a quality of the test chemical and thus the test element. Methods also are disclosed for detecting at least one analyte in a sample that include a quality measurement of the at least one test chemical of the test strip.Type: GrantFiled: May 14, 2014Date of Patent: April 4, 2017Assignee: Roche Diabetes Care, Inc.Inventors: Wolfgang Petrich, Carina Horn, Nelli Steinke, Christian Ringemann, Alexa Freifrau von Ketteler
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Publication number: 20170073728Abstract: Analytical apparatuses are disclosed for detecting at least one analyte in a sample, where in an analyte measurement at least an electrical or optical property changeable by presence of the analyte at least one test chemical of a test element is recorded, and where the analytical apparatus also can perform at least one quality measurement on the at least one test chemical such as an intrinsic luminescence, which is recorded and from the intrinsic luminescence a conclusion is drawn on a quality of the test chemical and thus the test element. Methods also are disclosed for detecting at least one analyte in a sample that include a quality measurement of the at least one test chemical of the test strip.Type: ApplicationFiled: November 22, 2016Publication date: March 16, 2017Inventors: Wolfgang Petrich, Carina Horn, Nelli Steinke, Christian Ringemann, Alexa Freifrau von Ketteler
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Patent number: 9326718Abstract: A system is proposed for detection of at least one analyte in a body fluid, in particular for detection of blood glucose. The system is designed to generate a sample of the body fluid and to transfer at least some of the sample to at least one test element, in particular a test panel. The system is designed such that a time period between the generation of the sample and the application to the test element is less than 1 second, preferably less than 500 ms.Type: GrantFiled: July 28, 2010Date of Patent: May 3, 2016Assignee: Roche Diabetes Care, Inc.Inventors: Wolfgang Petrich, Christian Vrancic, Daniel Wong, Paul Patel
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Patent number: 9329128Abstract: The invention relates to a test element for detecting at least one analyte in a sample, in particular for detecting at least one metabolite in a bodily fluid. The test element comprises at least one test field with a test field surface. The test field comprises at least one detection reagent that is adapted to undergo a detectable reaction in the presence of the analyte. The test element further comprises at least one distribution element that has at least one distribution surface facing the test field surface. Between the distribution surface and the test field surface is at least one capillary gap, wherein the capillary gap is adapted to allow a layer of the sample with a layer thickness of no more than 50 ?m to form within the capillary gap.Type: GrantFiled: October 15, 2013Date of Patent: May 3, 2016Assignee: Roche Diabetes Care, Inc.Inventors: Wolfgang Petrich, Luis David Bedon-Gomez
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Publication number: 20160090398Abstract: The invention also relates to compounds, which are useful for intra-molecular fluorescence resonance energy transfer (FRET), comprising the oxidized form of a carbaNADH-based first fluorophore and a second fluorophore that is excitable at a wave-length of between 445 to 540 nm and that has an emission maximum of greater than 560 nm, and methods, kits and compositions related thereto.Type: ApplicationFiled: December 4, 2015Publication date: March 31, 2016Inventors: Dieter Heindl, Joachim Hoenes, Carina Horn, Thomas Meier, Wolfgang Petrich
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Publication number: 20160076993Abstract: A device is proposed for detecting at least one analyte in a bodily fluid. The device comprises at least one test element with at least one two-dimensional evaluation region. The device furthermore comprises at least one spatially resolving optical detector having a plurality of pixels. The detector is designed to image at least part of the test element onto an image region. In the process, at least part of the evaluation region is imaged onto an evaluation image region. The detector is matched to the test element such that a predetermined minimum number of pixels is provided for each dimension within the evaluation image region. The pixels are arranged in a two-dimensional matrix arrangement. The matrix arrangement has pixel rows and pixel columns, wherein the pixel rows are arranged substantially parallel to a longitudinal direction of the evaluation region and/or of the evaluation image region.Type: ApplicationFiled: November 25, 2015Publication date: March 17, 2016Inventors: Wolfgang Petrich, Frank Weidner
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Publication number: 20160011120Abstract: Methods are provided for deriving/determining an analyte concentration that include recording measurement values during a time development indicating a progress of a detection reaction of at least one test substance and a body fluid sample and providing at least one measurement curve F(t) containing the measurement values, where the detection reaction is known to be influenced by the analyte concentration and at least one disturbance variable Y. The methods also include deriving an end value of the measurement curve to form a first variable x1, and deriving at least one fit parameter by taking into account an exponential characteristic of the measurement curve, and where the fit parameter forms at least one second variable x2. The methods further include deriving/determining the analyte concentration by using at least one multivariate evaluation algorithm adapted to combine x1 and x2. Also provided are computer programs and devices that incorporate the same.Type: ApplicationFiled: June 19, 2015Publication date: January 14, 2016Applicant: Roche Diabetes Care, Inc.Inventors: Christian Ringemann, Markus Plum, Wolfgang Petrich, Timo Ottenstein