Abstract: A system is proposed for detection of at least one analyte in a body fluid, in particular for detection of blood glucose. The system is designed to generate a sample of the body fluid and to transfer at least some of the sample to at least one test element, in particular a test panel. The system is designed such that a time period between the generation of the sample and the application to the test element is less than 1 second, preferably less than 500 ms.

Abstract: The invention relates to a test system for analyzing body fluids of the type comprising a test element tape carrying a plurality of test elements, a tape deflector for the test element tape for the selective application of body fluid, and a light source as well as a detector for optically analyzing test elements to which body fluid has been applied. The tape deflector has a rotatable optical element which acts as a deflection roller during transport of the test element tape. The optical element is positioned in the optical path between the light source and the detector.

Abstract: The invention relates to processes and devices for detecting an analyte in a sample by fluorescence measurement of a fluorophore, wherein the detection medium which contains a fluorophore or a precursor of the fluorophore is admixed with an absorber whose absorbance spectrum superimposes the fluorescence excitation range of the fluorophore. The system consisting of the fluorophore and the absorber, which is produced in the detection medium, has an altered effective fluorescence excitation range with an altered fluorescence excitation maximum. Illumination with fluorescence excitation light can take place within the range of this altered excitation maximum. The measured signal obtained from determining fluorescence emission exhibits only low dependence on the wavelength of the excitation light.

Abstract: A system for determining the concentration of an analyte in a liquid sample comprising a detection unit for detecting light intensities which are radiated from subareas of a detection area of a test element as well as an evaluation unit which determines a frequency distribution for the detected light intensities wherein the frequency distribution has at least one first maximum caused by unwetted subareas or at least one reference area and a second maximum caused by wetted subareas and selects at least one light intensity on the basis of the frequency distribution and determines the concentration of the analyte from the at least one selected light intensity.

Abstract: A test element analysis system for the analytical investigation of a liquid sample, comprising a test element including a carrier film having at least one flat side and a test field secured to the flat side and an evaluation instrument including a test element holder for positioning a test element in a measuring position, a measuring device for measuring the optically measurable change in the detection zone, and a housing within the measuring device is positioned. The test element is positioned in the measuring position in such a manner that a first partial section of the test element is located inside the housing and a second partial section is located outside of the housing to be easily accessible.

Abstract: A method is presented for determining the concentration of an analyte in a liquid sample using a reagent system. The reaction of the sample with the reagent system results in a change of the quantity of a fluorophore, the quantity of the fluorophore correlating with the concentration of the analyte, a characteristic measurement variable for the quantity of the fluorophore being measured, and the concentration of the analyte being determined using an evaluation algorithm on the basis of the measurement variable. The reagent system is integrated in an analysis system and the fluorescence lifetime of the fluorophore is used in the ascertainment of the concentration of the analyte.

Abstract: The invention relates to a test system for analyzing body fluids of the type comprising a test element tape carrying a plurality of test elements, a tape deflector for the test element tape for the selective application of body fluid, and a light source as well as a detector for optically analyzing test elements to which body fluid has been applied. The tape deflector has a rotatable optical element which acts as a deflection roller during transport of the test element tape. The optical element is positioned in the optical path between the light source and the detector.

Abstract: The invention relates to a test system for analyzing body fluids of the type comprising a test element tape carrying a plurality of test elements, a tape deflector for the test element tape for the selective application of body fluid, and a light source as well as a detector for optically analyzing test elements to which body fluid has been applied. The tape deflector has a rotatable optical element which acts as a deflection roller during transport of the test element tape. The optical element is positioned in the optical path between the light source and the detector.

Abstract: A system is described for determining the concentration of an analyte in a liquid by absorption measurement comprising a test element with a detection area which contains at least one reaction area with reagents for detecting the analyte which cause a change in the absorption behavior upon reaction with the analyte. The detection area contains at least one reference area in which the absorption behavior is substantially not changed when wetted by a sample having the analyte. Furthermore, the system contains a detection unit for the spatially resolved detection of light intensities which are received from the detection area and an evaluation unit for evaluating signals from the detection unit. Further embodiments of the system comprise reaction areas and reference areas arranged alternately in two dimensions.

Abstract: The invention relates to processes and devices for detecting an analyte in a sample by fluorescence measurement.

Abstract: A system for determining the concentration of an analyte in a liquid sample comprising a detection unit for detecting light intensities which are radiated from subareas of a detection area of a test element as well as an evaluation unit which determines a frequency distribution for the detected light intensities wherein the frequency distribution has at least one first maximum caused by unwetted subareas or at least one reference area and a second maximum caused by wetted subareas and selects at least one light intensity on the basis of the frequency distribution and determines the concentration of the analyte from the at least one selected light intensity.

Abstract: Assembly and method for measuring the concentration of an analyte in a biological matrix. The assembly includes an implantable optical-sensing element that comprises a body, and a membrane mounted on the body in a manner such that the membrane and the body define a cavity. The membrane is permeable to the analyte, but is impermeable to background species in the biological matrix. A refractive element is positioned in the cavity. A light source transmits light of a first intensity onto the refractive element, and a light detector receives light of a second intensity that is reflected from the cavity. A controller device optically coupled to the detector compares the first and second light intensities, and relates the intensities to analyte concentration.

Abstract: Test element analysis system for the analytical investigation of a sample, in particular of a body liquid of human beings or animals, comprising test elements (2) with a carrier film (5) and a test field (7) fixed to the flat side (6) of the carrier film (5), the test field (7) containing a reagent system the reaction of which with the sample (21) leads to an optically measurable change in the detection zone (24) which is characteristic for the analysis, and an evaluation instrument with a measuring device for measuring the optically measurable change.

Abstract: The invention relates to analysis methods for diagnosing diseases on human and animal samples. Said invention also relates to an evaluation method for diagnosing the individual stages of a disease in such a way that it is possible to display the progression thereof. Said invention also makes it possible to identify diseases in an early manner and to carry out therapeutic controls. The inventive method consists in carrying out actually known multivariable evaluation methods for classifying samples. Nevertheless, the invention is characterised in that no sample is allocated to a certain class, but it is classified in a data record based on the interpolation between different classes.

Abstract: A method is described for the spectroscopic examination of samples which are taken from human tissue or body fluids, in particular blood, comprising the following steps: measuring an infrared spectrum of a sample to be examined; analysing the measured infrared spectrum in order to determine at least one sample parameter that characterizes the infrared spectrum in at least one of the following wavenumber ranges 2850 cm?1 to 2886 cm?1, 2798 cm?1 to 2835 cm?1, 1723 cm?1 to 1733 cm?1, 1429 cm?1 to 1465 cm?1, 1338 cm?1 to 1364 cm?1, 1089 cm?1 to 1123 cm?1, 1034 cm?1 to 1074 cm?1, comparing the at least one sample parameter with at least one reference parameter that was obtained by analysing at least one reference spectrum that was measured on at least one sample of body fluid from patients afflicted by Alzheimer's, and assigning the sample to a class with an increased suspicion of Alzheimer's disease if the deviation of the at least one sample parameter from the at least one reference parameter does not exceed a p

Abstract: The present invention is generally directed towards a system for reagent-free determination of the concentration of an analyte in vivo. The system comprises a light transmitter for generating monochromatic primary light, a scattered-light percutaneous sensor which includes an inbound light guide and a detection light guide, a wavelength-selective detection device that is connected to the detection light guide for detection of Raman-scattered components of the secondary light and an evaluation device for determining the concentration of the analyte from the Raman-scattered components of the secondary light.

Abstract: Test element analysis system for the analytical investigation of a sample, in particular of a body liquid of human beings or animals, comprising test elements (2) with a carrier film (5) and a test field (7) fixed to the flat side (6) of the carrier film (5), the test field (7) containing a reagent system the reaction of which with the sample (21) leads to an optically measurable change in the detection zone (24) which is characteristic for the analysis, and an evaluation instrument with a measuring device for measuring the optically measurable change.

Abstract: The invention relates to a test system for analyzing body fluids of the type comprising a test element tape carrying a plurality of test elements, a tape deflector for the test element tape for the selective application of body fluid, and a light source as well as a detector for optically analyzing test elements to which body fluid has been applied. The tape deflector has a rotatable optical element which acts as a deflection roller during transport of the test element tape. The optical element is positioned in the optical path between the light source and the detector.

Abstract: The invention relates to processes and devices for detecting an analyte in a sample by fluorescence measurement.

Abstract: The invention relates to analysis methods for diagnosing diseases on human and animal samples. Said invention also relates to an evaluation method for diagnosing the individual stages of a disease in such a way that it is possible to display the progression thereof. Said invention also makes it possible to identify diseases in an early manner and to carry out therapeutic controls. The inventive method consists in carrying out actually known multivariable evaluation methods for classifying samples. Nevertheless, the invention is characterised in that no sample is allocated to a certain class, but it is classified in a data record based on the interpolation between different classes.