Patents by Inventor Wolfgang Reuter

Wolfgang Reuter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4401667
    Abstract: Compounds of the formula ##STR1## wherein A is phenyl, 4-hydroxy-phenyl, 2-thienyl, 3-thienyl or 3,4-dihydroxy-phenyl;Het is 4H-5,6-dioxo-1,2,4-triazin-3-yl, 4-methyl-5,6-dioxo-1,2,4-triazin-3-yl, 1-vinyl-tetrazol-5-yl, 1-allyl-tetrazol-5-yl or ##STR2## where n is an integer from 1 to 3, inclusive,R.sub.1 is hydroxyl, amino, dimethylamino, acetylamino, aminocarbonyl, aminocarbonylamino, aminosulfonyl, aminosulfonylamino, methylcarbonyl, methylsulfonylamino, cyano, hydroxysulfonylamino, methylsulfonyl, methylsulfinyl, a carboxylic acid group or a sulfonic acid group, or --(CH.sub.2).sub.n --R.sub.1 may also be alkyl of 2 to 4 carbon atoms or 2,3-dihydroxy-propyl;R.sub.
    Type: Grant
    Filed: November 20, 1981
    Date of Patent: August 30, 1983
    Assignee: Karl Thomae Gesellschaft mit beschrankter Haftung
    Inventors: Bernd Wetzel, Eberhard Woitun, Wolfgang Reuter, Roland Maier, Uwe Lechner, Hanns Goeth
  • Patent number: 4388315
    Abstract: Cephalosporins of the formula ##STR1## wherein A is phenyl, 4-hydroxyphenyl, cyclohexyl, cyclohexene-1-yl, cyclohexa-1,4-diene-1-yl, 2-thienyl, 3-thienyl, 2-furyl, 3-furyl or 3,4-disubstituted phenyl, where the substituents, which may be identical to or different from each other, are each chlorine, hydroxyl or methoxy;Y is hydrogen or methoxy;D is hydrogen, hydroxyl, acetoxy, aminocarbonyloxy, pyridinium, aminocarbonyl-pyridinium or the group S-Het, where Het is 1-methyl-tetrazol-5-yl, tetrazol-5-yl, 3-methyl-1,2,4-thiadiazol-5-yl,1,2,4-thiadiazol-5-yl, 1,3,4-thiadiazol-5-yl, 2-methyl-1,3,4-thiadiazol-5-yl, 2-methylamino-1,3,4-thiadiazol-5-yl, 2-dimethylamino-1,3,4-thiadiazol-5-yl, 2-formylamino-1,3,4-thiadiazol-5-yl , 2-acetylamino-1,3,4-thiadiazol-5-yl, 2-methyl-1,3,4-oxadiazol-5-yl, 1,2,3-triazol-4-yl or 1,2,4-triazol-3-yl;R is hydrogen, methyl, cyclopropyl, hydroxyl, methoxy, ethoxy, mercapto, morpholino, thiomorpholino, thiomorpholino-S-oxide, thiomorpholino-S,S-dioxide, ##STR2## E is hydrogen or a prote
    Type: Grant
    Filed: September 30, 1981
    Date of Patent: June 14, 1983
    Assignee: Boehringer Ingeleheim GmbH
    Inventors: Bernd Wetzel, Eberhard Woitun, Roland Maier, Wolfgang Reuter, Uwe Lechner, Hanns Goeth
  • Patent number: 4379784
    Abstract: Compounds of the formula ##STR1## wherein A is phenyl, 4-hydroxy-phenyl, 2-thienyl or 3,4-dihydroxy-phenyl; andR is ##STR2## where R.sub.1 and R.sub.2, which may be identical to or different from each other, are each methylmercapto or amino;Z' is oxygen, sulfur or .dbd.NR.sub.3 ;R.sub.3 is hydrogen, alkyl of 1 to 3 carbon atoms or hydroxy-(alkyl of 1 to 3 carbon atoms);R.sub.4 is hydrogen, hydroxyl, hydroxymethyl or methyl;n is 2, 3 or 4;Y is --SO.sub.2 NH--, --SO-- or --SO.sub.2 --;Z is straight or branched alkylene of 1 to 3 carbon atoms;X is hydroxyl, aminocarbonyl, aminosulfonyl, formylamino, acetylamino, amino, methylsulfinyl, methylsulfonyl or ##STR3## or --Y--Z--X is ##STR4## and non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases. The compounds as well as the salts are useful as antibiotics.
    Type: Grant
    Filed: November 20, 1981
    Date of Patent: April 12, 1983
    Assignee: Dr. Karl Thomae Gesellschaft mit beschrankter Haftung
    Inventors: Roland Maier, Bernd Wetzel, Eberhard Woitun, Wolfgang Reuter, Uwe Lechner, Hanns Goeth
  • Patent number: 4370327
    Abstract: The invention is directed to cephalosporins of the formula ##STR1## and the tautomers thereof, and, when E is a hydrogen atom, the pharmacologically acceptable salts thereof with inorganic or organic bases.
    Type: Grant
    Filed: February 23, 1981
    Date of Patent: January 25, 1983
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Bernd Wetzel, Eberhard Woitun, Wolfgang Reuter, Roland Maier, Uwe Lechner, Hanns Goeth
  • Patent number: 4364944
    Abstract: Compounds of the formula ##STR1## wherein Y is hydrogen or methoxy;A is ##STR2## or, when Y is methoxy, also phenyl, 4-hydroxy-phenyl, 2-thienyl, 3-thienyl of 3,4-dihydroxy-phenyl;A' is hydrogen, --COCH.sub.2 Cl, --COCH.sub.2 Br, --COOCH.sub.2 CCL.sub.3, formyl or trityl;D is hydrogen, acetoxy, aminocarbonyloxy, pyridinium, 4-aminocarbonyl-pyridinium or -S-Het, where Het is 3-methyl-1,2,4-thiadiazol-5-yl, 1,2,4-thiadiazol-5-yl, 1,3,4-thiadiazol-5-yl, 2-methyl-1,3,4-thiadiazol-5-yl, 4H-5,6-dioxo-1,2,4-triazine-3-yl, 4-methyl-5,6-dioxo-1,2,4-triazin-3-yl, 1-vinyl-tetrazol-5-yl, 1-allyl-tetrazol-5-yl or ##STR3## n is 1, 2 or 3; R.sub.1 is hydroxyl, amino, dimethylamino, acetylamino, aminocarbonyl, aminocarbonylamino, aminosulfonyl, aminosulfonylamino, methylcarbonyl, methylsulfonylamino, cyano, hydroxysulfonylamino, methylsulfonyl, methylsulfinyl, a carboxylic acid group or a sulfonic acid group; or--(CH.sub.2).sub.n R.sub.1 is alkyl of 1 to 4 carbon atoms or 2,3-dihydroxy-propyl;R.sub.
    Type: Grant
    Filed: November 20, 1981
    Date of Patent: December 21, 1982
    Assignee: Dr. Karl Thomae Gesellschaft mit beschrankter Haftung
    Inventors: Bernd Wetzel, Eberhard Woitun, Wolfgang Reuter, Roland Maier, Uwe Lechner, Hanns Goeth
  • Patent number: 4362725
    Abstract: Compounds of the formula ##STR1## wherein A is phenyl, 4-hydroxy-phenyl, 2-thienyl, 2-furyl or 3,4-dihydroxy-phenyl;Y is hydrogen or methoxy;Het is 4H-5,6-dioxo-1,2,4-triazin-3-yl,4-methyl-5,6-dioxo-1,2,4-triazin-3-yl,2-methyl-5,6-dioxo-1,2,4-triazin-3-yl,1-vinyl-tetrazol-5-yl, 1-allyl-tetrazol-5-yl or ##STR2## where n is an integer from 1 to 3, inclusiveR.sub.1 is hydroxyl, amino, dimethylamino, acetylamino, aminocarbonyl, aminocarbonylamino, aminosulfonyl, aminosulfonylamino, methylcarbonyl, methylsulfonylamino, cyano, hydroxysulfonylamino, methylsulfonyl, methylsulfinyl, a carboxylic acid group or a sulfonic acid group, and--(CH.sub.2).sub.n --R.sub.1 may also be alkyl of 2 to 4 carbon atoms or 2,3-dihydroxy-propyl;R is cyclopropyl, 4'-hydroxycyclohexyl-amino ##STR3## where R.sub.
    Type: Grant
    Filed: September 28, 1981
    Date of Patent: December 7, 1982
    Assignee: Dr. Karl Thomae Gesellschaft mit beschrankter Haftung
    Inventors: Bernd Wetzel, Eberhard Woitun, Wolfgang Reuter, Roland Maier, Uwe Lechner, Hanns Goeth
  • Patent number: 4289775
    Abstract: Compounds of the formula ##STR1## wherein A is phenyl, p-hydroxy-phenyl, 2-thienyl, 3-thienyl or 3,4-disubstituted phenyl, where the substituents, which may be identical to or different from each other, are each chlorine, hydroxyl or methoxy;R is --NH--Z--X;Z is straight or branched alkylene of 1 to 6 carbon atoms or cycloalkylene of 3 to 6 carbon atoms;X is cyano, hydroxyl, mercapto, aminocarbonyl, aminosulfonyl, ##STR2## R.sub.1 is straight or branched alkyl of 1 to 4 carbon atoms or phenyl; R.sub.2 is hydrogen or alkyl of 1 to 4 carbon atoms; andR.sub.1 and R.sub.2, together with an adjacent nitrogen atom to which they are attached, form a 3- to 6-membered heterocyclic ring;and non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases.
    Type: Grant
    Filed: May 14, 1980
    Date of Patent: September 15, 1981
    Assignee: Karl Thomae GmbH
    Inventors: Bernd Wetzel, Eberhard Woitun, Wolfgang Reuter, Roland Maier, Uwe Lechner, Hanns Goeth
  • Patent number: 4256738
    Abstract: Compounds of the formulaR--NH--(CH.sub.2).sub.n --NH--EwhereinR is a pyrimidinyl, a quinazolinyl, a 5,6,7,8-tetrahydro-quinazolinyl, a thieno[3,2,-d]pyrimidinyl, a thieno[2,3-d]pyrimidyl, a pyrido[3,2-d]primidinyl, a 5,6-dihydro-4-pyrido[3,4-d]pyrimidinyl, an isothiazola [5,4-d]pyrimidinyl or a pyrimido[4,5-d]-pyrimidinyl group;n is 2 or 3; andE is the 9-erythromycyl group;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antibacterials.
    Type: Grant
    Filed: November 3, 1978
    Date of Patent: March 17, 1981
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Eberhard Woitun, Bernd Wetzel, Roland Maier, Wolfgang Reuter, Uwe Lechner, Rolf G. Werner, Hanns Goeth
  • Patent number: 4241056
    Abstract: Compounds of the formula ##STR1## wherein A is phenyl; 4-hydroxy-phenyl; 2- or 3-thienyl; cyclohexyl; cyclohexen-1-yl; cyclohexa-1, 4-dien-1-yl; or 3,4-disubstituted phenyl, where the substituents may be identical to or different from each other and are selected from the group consisting of chlorine, hydroxyl or methoxy; andR is an aliphatic, cycloaliphatic; aromatic or heterocyclic group of diverse types;and non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases. The compounds as well as their salts are useful as antibiotics.
    Type: Grant
    Filed: February 21, 1979
    Date of Patent: December 23, 1980
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Bernd Wetzel, Wolfgang Reuter, Eberhard Woitun, Roland Maier, Uwe Lechner, Hanns Goeth, Rolf Werner
  • Patent number: 4173647
    Abstract: The compound of the formula ##STR1## and non-toxic, pharmacologically acceptable acid addition salts thereof. The compound as well as its salts are useful as antimicrobials.
    Type: Grant
    Filed: December 4, 1978
    Date of Patent: November 6, 1979
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Roland Maier, Eberhard Woitun, Wolfgang Reuter, Bernd Wetzel, Hanns Goeth, Uwe Lechner
  • Patent number: 4140058
    Abstract: A cartridge case and a process for the production thereof wherein the cartridge case includes an elongated tubular member and a separate bottom part. The separate bottom part is insertable in said elongated tubular member such that at least a portion of the wall surfaces of said bottom part and said tubular member contact one another and at least one of said separate bottom part and said elongated tubular member in the region of the wall surfaces to be contacted is provided with transfer elements. The transfer element means are responsive to ultrasonic energy for joining said bottom part and said elongated tubular member together such that a cartridge case is formed especially utilizable as a shot cartridge case.
    Type: Grant
    Filed: August 18, 1976
    Date of Patent: February 20, 1979
    Assignee: Dynamit Nobel Aktiengesellschaft
    Inventors: Kurt Ballreich, Hans Umbach, Jurgen Ahlborn, Wolfgang Reuter
  • Patent number: 4095759
    Abstract: This invention relates to an improvement in a device for the stabilization of a captive aircraft with a drive unit for rotor blades which produce lift with the aid of thrust, wherein a mooring line engages below the aircraft center of gravity, and wherein the device includes a control device intervening in the drive unit and the rotor blades for producing thrust,The improvement comprisingA position regulator and translation damper for the purpose of influencing controls for the rolling and pitching axes,An angular velocity regulator for the purpose of influencing yaw control, andA cable line traction regulator operating in dependence upon cable line traction in immediate proximity to the aircraft, and in dependence upon an output or power regulator for the drive unit, for the purpose of influencing output power regulation and the rotor blades for producing lift.
    Type: Grant
    Filed: May 6, 1976
    Date of Patent: June 20, 1978
    Assignee: Dornier GmbH
    Inventors: Heinz Woitschella, Wolfgang Reuter, Rolf Swik
  • Patent number: 4058277
    Abstract: An improvement is disclosed in a helicopter adapted to fly while moored to a ground station, being remote-controlled therefrom and having a device for automatic stabilization of the flight attitude, and in which the mooring cable is wound-on and wound-off of a cable drum by a drive device, the improvement comprising a stabilizer in the helicopter adapted to be switched to different operating ranges, and a switching device in the ground station coupled with the cable drum, the switching device being adapted to transmit signals for the stabilizer in dependence upon the wound-off length of the mooring cable.
    Type: Grant
    Filed: July 28, 1976
    Date of Patent: November 15, 1977
    Assignee: Dornier GmbH.
    Inventors: Hugo Kozakiewicz, Wolfgang Reuter
  • Patent number: 4048306
    Abstract: The invention relates to novel erythromycin derivatives, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as the salts are useful as antibacterials.
    Type: Grant
    Filed: March 29, 1976
    Date of Patent: September 13, 1977
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Roland Maier, Eberhard Woitun, Bernd Wetzel, Wolfgang Reuter, Hanns Goeth, Uwe Lechner
  • Patent number: 4016263
    Abstract: Compounds of the formula ##STR1## wherein E is ##STR2## R.sub.1 is hydrogen; straight or branched alkyl of 1 to 3 carbon atoms; (alkoxy of 1 to 5 carbon atoms)-(alkyl of 1 to 3 carbon atoms); phenyl; or benzyl;R.sub.2 is hydrogen; hydroxyl; straight or branched alkyl of 1 to 3 carbon atoms; or phenyl;R.sub.
    Type: Grant
    Filed: March 29, 1976
    Date of Patent: April 5, 1977
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Bernd Wetzel, Eberhard Woitun, Roland Maier, Wolfgang Reuter, Hanns Goeth, Uwe Lechner
  • Patent number: 3932642
    Abstract: Biocidal pharmaceutical compositions containing as an active ingredient a compound of the formula ##SPC1##WhereinR is free amino; lower aliphatic acylamino optionally mono- or di-chloro-substituted on the acyl moiety; (straight or branched monoalkyl of 1 to 5 carbon atoms)-amino; di(alkyl of 1 to 4 carbon atoms)amino, where the alkyl moieties may be identical to or different from each other; mono- or di-hydroxy (straight or branched alkyl of 1 to 5 carbon atoms) amino, where the amino nitrogen may have an alkyl of 1 to 4 carbon atoms substituent attached thereto; di-[hydroxy (straight or branched alkyl of 1 to 3 carbon atoms)]amino; alkoxy of 1 to 2 carbon atoms (alkyl of 1 to 3 carbon atoms)amino; free amino (alkyl of 1 to 3 carbon atoms)amino; N-acetyl-(alkylene of 1 to 3 carbon atoms)-diamino; piperidino; or hydroxy-piperidino; andR.sub.1 and R.sub.
    Type: Grant
    Filed: July 19, 1974
    Date of Patent: January 13, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Eberhard Woitun, Wolfgang Reuter