Patents by Inventor Wolfgang Schaefer

Wolfgang Schaefer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTISPECIFIC ANTIBODIES
    Publication number: 20150166670
    Abstract: The present invention relates to bivalent, multispecific antibodies, especially bivalent, trispecific antibodies which bind to human HER1, human HER2, and human HER3, their manufacture and use.
    Type: Application
    Filed: November 24, 2014
    Publication date: June 18, 2015
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: RAFFAELLA CASTOLDI, ALEXANDER HAAS, CHRISTIAN KLEIN, WOLFGANG SCHAEFER, CLAUDIO SUSTMANN
  • BISPECIFIC, TETRAVALENT ANTIGEN BINDING PROTEINS
    Publication number: 20150044214
    Abstract: The present invention relates to bispecific, tetravalent antigen binding proteins, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: April 18, 2014
    Publication date: February 12, 2015
    Applicant: HOFFMANN-LA ROCHE, INC.
    Inventors: Sabine IMHOF-JUNG, Christian KLEIN, Joerg Thomas REGULA, Wolfgang SCHAEFER, Juergen Michael SCHANZER
  • Bispecific, bivalent anti-VEGF/anti-ANG-2 antibodies
    Patent number: 8945552
    Abstract: The present invention relates to bispecific, bivalent antibodies against human vascular endothelial growth factor (VEGF/VEGF-A) and against human angiopoietin-2 (ANG-2), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: February 3, 2015
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Monika Baehner, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas, Wolfgang Schaefer, Kay-Gunnar Stubenrauch, Markus Thomas
  • TRI- OR TETRASPECIFIC ANTIBODIES
    Publication number: 20150030598
    Abstract: The present invention relates to tri- or tetraspecific antibodies, their manufacture and use.
    Type: Application
    Filed: June 25, 2014
    Publication date: January 29, 2015
    Inventors: Rebecca CROASDALE, Christian KLEIN, Wolfgang SCHAEFER, Juergen Michael SCHANZER
  • BISPECIFIC ANTI-VEGF/ANTI-ANG-2 ANTIBODIES
    Publication number: 20150004166
    Abstract: The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: February 27, 2014
    Publication date: January 1, 2015
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Monika Baehner, Ulrich Brinkmann, Guy Georges, Remko Albert Griep, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Stefan Seeber, Markus Thomas
  • UV hardening glass printing ink and UV hardening glass printing lacquer and method for printing a glass substrate
    Patent number: 8916656
    Abstract: A glass printing ink and a glass printing lacquer comprising at least one pigment, at least one photoinitiator, at least two resins and radicial photoinitiators. One resin is an epoxy resin having an average molecular weight based on bisphenol A, diluted in a UV hardening monomer. The other resin is a resin which contains free functional amino, hydroxy, epoxy, acid, acid anhydride and/or acrylate groups. Also, the use of the glass printing ink and glass printing lacquer when printing a glass substrate and to a method for printing a glass substrate.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: December 23, 2014
    Assignee: Marabu GmbH & Co., KG
    Inventors: Saskia Lehmann, Wolfgang Schaefer
  • Method for producing a multilayer compound on a CIP-capable coating installation and use of the multilayer compound produced by said method for transdermal application or the application in body cavities
    Patent number: 8864047
    Abstract: Methods for producing a mono- or multilayer composite are provided in which one or several layers are applied onto a carrier material by coating, the coated mono- or multilayer composite is dried and rolled up, and the installation is subsequently cleaned. The air circuit in the drying oven is entirely set to fresh air supply, and the drying oven is configured to be cleaned in a controlled manner. All components of the drying oven that come into contact with the product do not have to be removed during cleaning, but can be cleaned-in-place using technology integrated into the drying oven. The drying oven Outer housing is designed so that it can be lifted upwardly. All assembly parts in the drying oven interior are designed to eliminate disassembling for cleaning purposes. Transport rollers within the drying oven are designed as hollow shafts and provided with spraying nozzles.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: October 21, 2014
    Assignee: LTS Lohmann Therapie-Systeme AG
    Inventors: Rudi Brathuhn, Peter Schwarz, Wolfgang Schaefer
  • Laminate coated with radiation-hardenable printing ink or printing lacquer and moulded piece
    Patent number: 8840986
    Abstract: The present invention relates to printing ink or printing lacquer containing non radiation-hardenable polycarbonate, preferably, aromatic, in particular as a binder and adhesion promoting components. According to the invention, the polycarbonate is present with radiation-hardening monomers, in particular dissolved therein.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: September 23, 2014
    Assignee: Bayer MaterialScience AG
    Inventors: Roland Künzel, Klaus Meyer, Norbert Kinzel, Wolfgang Schäfer, Martin Hauck
  • UV-curing glass printing ink and UV-curing glass printing lacquer and process for printing glass substrates
    Patent number: 8835530
    Abstract: A glass printing ink and glass printing lacquer are prepared, which contain at least one photoinitiator, at least one resin and at least one additional substance. The resin is an epoxy resin based on bisphenol A, diluted in a UV-curing monomer, or a resin with functional groups containing free functional amino, hydroxy, epoxy, acid, acid anhydride and/or acrylate groups, or a combination of the epoxy resin with the resin with functional groups. The at least one additional substance is a wax. The use of the glass printing ink and glass printing lacquer in printing a glass substrate and processes for the printing of a glass substrate are also described.
    Type: Grant
    Filed: January 4, 2007
    Date of Patent: September 16, 2014
    Assignee: Marabu GmbH & Co., KG
    Inventors: Wolfgang Schaefer, Dimitrios Triantafillidis
  • Tri- or tetraspecific antibodies
    Patent number: 8796424
    Abstract: The present invention relates to tri- or tetraspecific antibodies, their manufacture and use.
    Type: Grant
    Filed: May 27, 2010
    Date of Patent: August 5, 2014
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Rebecca Croasdale, Christian Klein, Wolfgang Schaefer, Juergen Michael Schanzer
  • BIVALENT, BISPECIFIC ANTIBODIES
    Publication number: 20140120613
    Abstract: The present invention relates to a host cell for use in the expression of a novel domain exchanged, bivalent, bispecific antibody.
    Type: Application
    Filed: August 30, 2013
    Publication date: May 1, 2014
    Applicant: Hoffman-La Roche Inc.
    Inventors: Christian KLEIN, Wolfgang SCHAEFER
  • Bispecific anti-VEGF/anti-ANG-2 antibodies
    Patent number: 8703130
    Abstract: The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: August 9, 2012
    Date of Patent: April 22, 2014
    Assignee: Hoffmann-La Roche, Inc.
    Inventors: Monika Baehner, Ulrich Brinkmann, Guy Georges, Remko Albert Griep, Sabine Imhof-Jung, Anita Kavlie, Hubert Kettenberger, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer, Werner Scheuer, Stefan Seeber, Markus Thomas
  • Bispecific, tetravalent antigen binding proteins
    Patent number: 8703132
    Abstract: The present invention relates to bispecific, tetravalent antigen binding proteins, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: April 22, 2014
    Assignee: Hoffmann-La Roche, Inc.
    Inventors: Sabine Imhof-Jung, Christian Klein, Joerg Thomas Regula, Wolfgang Schaefer, Juergen Michael Schanzer
  • UV HARDENING GLASS PRINTING INK AND UV HARDENING GLASS PRINTING LACQUER AND METHOD FOR PRINTING A GLASS SUBSTRATE
    Publication number: 20140031446
    Abstract: A glass printing ink and a glass printing lacquer comprising at least one pigment, at least one photoinitiator, at least two resins and radicial photoinitiators. One resin is an epoxy resin having an average molecular weight based on bisphenol A, diluted in a UV hardening monomer. The other resin is a resin which contains free functional amino, hydroxy, epoxy, acid, acid anhydride and/or acrylate groups. Also, the use of the glass printing ink and glass printing lacquer when printing a glass substrate and to a method for printing a glass substrate.
    Type: Application
    Filed: July 1, 2013
    Publication date: January 30, 2014
    Applicant: MARABUWERKE GMBH & CO. KG
    Inventors: Saskia Lehmann, Wolfgang Schaefer
  • POLYPEPTIDE-POLYNUCLEOTIDE-COMPLEX AND ITS USE IN TARGETED EFFECTOR MOIETY DELIVERY
    Publication number: 20130344094
    Abstract: Herein is reported a polypeptide-polynucleotide-complex as therapeutic agent and its use as tool for the targeted delivery of an effector moiety. The polynucleotide part of the complex is essentially resistant to proteolytic and enzymatic degradation in vivo. Additionally the polypeptide part specifically binds to a compound or structure such as a tissue or organ, a process or a disease. Thus, one aspect as reported herein is a polypeptide-polynucleotide-complex comprising a) a polypeptide specifically binding to a target and conjugated to a first member of a binding pair, b) a polynucleotide linker conjugated at its first terminus to the second member of the binding pair, and c) an effector moiety conjugated to a polynucleotide that is complementary to at least a part of the polynucleotide linker.
    Type: Application
    Filed: June 21, 2013
    Publication date: December 26, 2013
    Inventors: Michael Gerg, Dieter Heindl, Gerhard Niederfellner, Wolfgang Schaefer, Michael Schraeml, Michael Tacke
  • Method for Neutralizing or Recycling Carrier Materials for Film-like Coatings
    Publication number: 20130326901
    Abstract: The present invention relates to methods by which to produce sheet-like, wafer-like or film-like forms of drugs, confectionary, other food, cosmetics and the like for oral application or intake. The present invention is more particularly directed to the thermal treatment of carrier materials used in the production of such sheet-like, wafer-like or film-like forms. The thermal treatment removes contaminating or undesired substances from the carrier material.
    Type: Application
    Filed: August 16, 2013
    Publication date: December 12, 2013
    Applicant: LTS LOHMANN THERAPIE-SYSTEME AG
    Inventors: Detlev NEULAND, Wolfgang SCHAEFER, Peter SCHWARZ
  • Radiation-curable printing ink or printing varnish
    Patent number: 8580878
    Abstract: The invention relates to a printing ink or printing varnish containing non-radiation-curable, preferably aromatic polycarbonate, in particular as a binder and adhesive component. According to the invention, the polycarbonate is provided with radiation-curable monomers, in particular is dissolved therein.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: November 12, 2013
    Assignee: Marabu GmbH & Co. KG
    Inventors: Martin Hauck, Wolfgang Schaefer, Roland Kuenzel, Klaus Meyer, Norbert Kinzel
  • Rotor Blade Pitch Adjustment Device
    Publication number: 20130243624
    Abstract: A rotor blade pitch adjustment device for a wind power installation includes a motor/pump unit whose rotation speed and direction are variable and which is connected for fluid-flow purposes to a hydraulic actuator via a hydraulic open-loop/closed-loop control system. The actuator is mechanically coupled to at least one rotor blade of the wind power installation in order to rotate the rotor blade about its longitudinal axis. An electrical control circuit, which comprises an emergency power supply device, is provided for operation of the motor.
    Type: Application
    Filed: April 8, 2011
    Publication date: September 19, 2013
    Inventors: Wolfgang Schaefer, Martin Laube, Bastian Beckmann
  • Method for neutralizing or recycling carrier materials for film-like coatings
    Patent number: 8529807
    Abstract: The present invention relates to methods by which to produce sheet-like, wafer-like or film-like forms of drugs, confectionary, other food, cosmetics and the like for oral application or intake. The present invention is more particularly directed to the thermal treatment of carrier materials used in the production of such sheet-like, wafer-like or film-like forms. The thermal treatment removes contaminating or undesired substances from the carrier material.
    Type: Grant
    Filed: January 14, 2003
    Date of Patent: September 10, 2013
    Assignee: LTS Lohmann Therapie-Systeme AG
    Inventors: Detlev Neuland, Wolfgang Schaefer, Peter Schwarz
  • Glass printing ink or lacquer of epoxy resin, other resin and photoinitiator
    Patent number: 8501876
    Abstract: The invention relates to a glass printing ink and a glass printing lacquer comprising at least one pigment, at least one photoinitiator and at least two resins. One resin is an epoxy resin having an average molecular weight based on bisphenol A, diluted in a UV hardening monomer. Another resin is a resin which contains free functional amino, hydroxy, epoxy, acid, acid anhydride and/or acrylate groups. The invention also relates to the use of the glass printing ink and glass printing lacquer when printing a glass substrate and to a method for printing a glass substrate.
    Type: Grant
    Filed: October 20, 2004
    Date of Patent: August 6, 2013
    Assignee: Marabuwerke GmbH & Co. KG
    Inventors: Saskia Lehmann, Wolfgang Schaefer