Abstract: Disclosed is a shoe including an upper for receiving a foot and a sole unit with a heel region and forefoot region, wherein an additional weight is arranged in at least one of the forefoot region and the heel region of the sole unit to stabilize the foot against at least one torque acting on a wearer's foot.

Abstract: A highly efficient method for generating human antibodies using recall technology is provided. In one aspect, human antibodies which are specific to the anthrax toxin are provided. In one aspect, human peripheral blood cells that have been pre-exposed to anthrax toxin are used in the SCID mouse model. This method results in high human antibody titers which are primarily of the IgG isotype and which contain antibodies of high specificity and affinity to desired antigens. The antibodies generated by this method can be used therapeutically and prophylactically for preventing or treating mammals exposed to anthrax. Thus, in one embodiment, a prophylactic or therapeutic agent used to counter the effects of anthrax toxin, released as a mechanism of bioterrorism, is provided. In one embodiment, a formulation and method for preventing and/or treating anthrax infection comprising a binding agent that prevents the assembly of the PA63 heptamer is also provided.

Abstract: The disclosure relates to an actuating drive for control of an actuating element for automation in process installations. An exemplary actuating device drive for control of an actuating element comprising: a position detection device configured for detection of an actual position of the actuating element; a regulator unit configured for operational connection with the position detection device for comparison of an actual position with a predeterminable set position and for production of an actuating signal for driving the actuating drive, wherein the position detection device has a pattern support, at least part of whose surface is covered by a pattern which can be scanned optically; and a stationary optical scanning device, whose optical axis is aligned with the pattern.

Abstract: The disclosure relates to a differential pressure transducer unit comprising an over-load protection system which is used to measure low differential pressure in liquids and gases under high static pressure load which can be connected to flanges on the working pressure lines. The differential pressure transducer unit consists of a planar multi-layered arrangement comprising layers which are conductive, insulating and which are insulated from each other, whereby the insulating and conductive layers comprises recesses which at least partially cover each other, wherein the measuring mechanism and the measuring value processing means are accommodated. At least one of the layers is a functional component of the over-load protection system.

Abstract: A highly efficient method for generating human antibodies using recall technology is provided. In one aspect, human antibodies which are specific to the anthrax toxin are provided. In one aspect, human peripheral blood cells that have been pre-exposed to anthrax toxin are used in the SCID mouse model. This method results in high human antibody titers which are primarily of the IgG isotype and which contain antibodies of high specificity and affinity to desired antigens. The antibodies generated by this method can be used therapeutically and prophylactically for preventing or treating mammals exposed to anthrax. Thus, in one embodiment, a prophylactic or therapeutic agent used to counter the effects of anthrax toxin, released as a mechanism of bioterrorism, is provided. In one embodiment, a formulation and method for preventing and/or treating anthrax infection comprising a binding agent that prevents the assembly of the PA63 heptamer is also provided.

Abstract: A modular shoe includes an upper with an upper side and a lower side, a chassis releasably arranged in an interior of the upper, and a plurality of studs. Each stud is releasably attached to the chassis through the lower side of the upper. The lower side of the upper is clamped between the chassis and at least one of the attached studs. The invention also relates to the various components used in a modular shoe in accordance with the invention.

Abstract: The invention relates to a shoe, in particular a sprint shoe, including a plate arranged in a sole area of the shoe. The plate extends essentially over the complete length of the sole area and is substantially planar in a forefoot part and is constructed of a material and configured to allow for elastic bending of the plate in the longitudinal direction, and is configured to three-dimensionally encompasses a rearfoot part of the foot. Optionally, the plate includes a heel cup in the rearfoot part to cradle the foot. Further, a wedge- or rib-like raised part may be arranged below the heel cup.

Abstract: The disclosure relates to a control device for a pneumatically operated actuator in the field of process automation, in particular for continuous control of material flows in the industrial environment. The control device has a communications interface for receiving an electrical setpoint value, and an output for the output of a pneumatic fluid, whose pressure is varied as a function of a control deviation. The received electrical setpoint value is suitable as a process parameter. The control device is connected via a communications channel to an actual-value encoder, which is designed to output an electrical signal corresponding to the actual value of the same process parameter.

Abstract: A modular medical care system, housing a plurality of different modules providing different functions used in delivering healthcare to a patient, includes a plurality of different modules including: (a) a patient monitoring module for acquiring and processing signals derived from sensors suitable for attachment to a patient; and (b) a patient treatment module for delivering treatment to the patient. A processor processes signals derived from the plurality of different modules. A communication interface provides bidirectional communication between the processor and the plurality of different modules via a network.

Abstract: The diagnostic device for detecting a failure of a sensing means, which sensing means comprises a recording means for repeatedly recording pairs of two absolute pressure values, the absolute pressure values being related to absolute pressures in the first and the second impulse lines, respectively, a computation means for repeatedly computing, from a prescribable number of pairs of the two absolute pressure values, a correlation value representative of the correlation between the two absolute pressure value, a comparison means for comparing correlation values to at least one correlation threshold value, and an output means for outputting a diagnostic output depending on the result of the comparison. It is possible to derive the absolute pressure values from one differential pressure measurement an one absolute pressure measurement.

Abstract: A MCM system board uses a stiffener arrangement to enhance mechanical, thermo and electrical properties by incorporating an LGA compression connector in a computer system. The present designs of large scale computing systems (LSCS) in IBM use a MCM that is attached to a system board and held together by a stiffening frame. Due to the nature of the manufacturing of the system board, there can be significant gaps formed in the mounting area of the MCM between the board and the stiffener. A method is described that not only fills the void, it also, in addition promotes thermo conduction of excess heat away from the MCM and at the same time promotes enhanced electrical properties of the LGA connections of the MCM to the system board.

Abstract: A highly efficient method for generating human antibodies using recall technology is provided. In one aspect, human antibodies which are specific to the anthrax toxin are provided. In one aspect, human peripheral blood cells that have been pre-exposed to anthrax toxin are used in the SCID mouse model. This method results in high human antibody titers which are primarily of the IgG isotype and which contain antibodies of high specificity and affinity to desired antigens. The antibodies generated by this method can be used therapeutically and prophylactically for preventing or treating mammals exposed to anthrax. Thus, in one embodiment, a prophylactic or therapeutic agent used to counter the effects of anthrax toxin, released as a mechanism of bioterrorism, is provided. In one embodiment, a formulation and method for preventing and/or treating anthrax infection comprising a binding agent that prevents the assembly of the PA63 heptamer is also provided.

Abstract: A MCM system board uses a stiffener arrangement to enhance mechanical, thermo and electrical properties by incorporating an LGA compression connector in a computer system. The present designs of large scale computing systems (LSCS) in IBM use a MCM that is attached to a system board and held together by a stiffening frame. Due to the nature of the manufacturing of the system board, there can be significant gaps formed in the mounting area of the MCM between the board and the stiffener. A method is described that not only fills the void, it also, in addition promotes thermo conduction of excess heat away from the MCM and at the same time promotes enhanced electrical properties of the LGA connections of the MCM to the system board.

Abstract: A highly efficient method for generating human antibodies using recall technology is provided. In one aspect, human antibodies which are specific to the anthrax toxin are provided. In one aspect, human peripheral blood cells that have been pre-exposed to anthrax toxin are used in the SCID mouse model. This method results in high human antibody titers which are primarily of the IgG isotype and which contain antibodies of high specificity and affinity to desired antigens. The antibodies generated by this method can be used therapeutically and prophylactically for preventing or treating mammals exposed to anthrax. Thus, in one embodiment, a prophylactic or therapeutic agent used to counter the effects of anthrax toxin, released as a mechanism of bioterrorism, is provided. In one embodiment, a formulation and method for preventing and/or treating anthrax infection comprising a binding agent that prevents the assembly of the PA63 heptamer is also provided.

Abstract: A method for managing patient ventilator operation includes receiving data representing one or more hemodynamic parameters. In response to the received data representing the one or more hemodynamic parameters, one or more commands are provided for adaptively altering ventilator operation.

Abstract: The invention relates to a measurement transmitter for operation in a process plant. The enclosure of the measurement transmitter comprises two mutually separate containers (11, 12), where the transducer for converting the process-related, physical variable into an appropriate electrical variable is housed in the one container (11), and an electronic circuit (22) is arranged in the other container (12). The two containers (11, 12) have complimentary screw threads (51, 52) to each other, and are screwed together directly. The screw connection of the two containers (11, 12) comprises a transformer made up of two parts (31, 32), whose parts (31, 32) each comprise a winding (41, 42) connected to the circuitry (21, 22) of the respective container (11, 12).

Abstract: The invention relates to a shoe having a sole element. The sole element includes a sole area extending below a wearer's foot and a heel cup three-dimensionally encompassing a heel of the wearer's foot. The heel cup alone forms at least a portion of a sidewall of the shoe.

Abstract: The invention relates to a device and a method for the status monitoring of a pressure measuring unit in an absolute or differential or relative pressure transducer, a pressure-sensitive element installed in the pressure measuring unit being impinged with at least one pressure generated by at least one membrane. During a defined diagnosis time interval, a testing element integrated in the pressure measuring unit is induced to undergo a change in volume, preferably by electrical activation. The pressure difference caused as a result in the pressure measuring unit is registered by a pressure-sensitive element. The curve registered during a diagnosis time interval is compared with a reference curve recorded with the pressure measuring unit intact. A fault indication is given if the deviations between the registered curve and the reference curve exceed predetermined tolerance values.

Abstract: Exemplary embodiments are directed to processing a sensor signal using the correction parameters assigned to the sensor. A pressure transducer is disclosed for measuring and converting absolute pressure and/or differential pressure into an adequate electrical measurement signal with the aid of a processing unit having an associated read-only memory, in which is stored a set of correction parameters for correcting the measurement signal.

Abstract: A MCM system board uses a stiffener arrangement to enhance mechanical, thermo and electrical properties by incorporating an LGA compression connector in a computer system. The present designs of large scale computing systems (LSCS) in IBM use a MCM that is attached to a system board and held together by a stiffening frame. Due to the nature of the manufacturing of the system board, there can be significant gaps formed in the mounting area of the MCM between the board and the stiffener. A method is described that not only fills the void, it also, in addition promotes thermo conduction of excess heat away from the MCM and at the same time promotes enhanced electrical properties of the LGA connections of the MCM to the system board.