Abstract: The present invention relates to a monoclonal antibody or a fragment thereof that recognizes and binds specifically to the extracellular domain of endothelin receptor type A as an antigen. The monoclonal antibody of the present invention is suitable for use in a therapeutic agent for hypertension or cancer associated with endothelin receptor type A.

Abstract: Provided is a polypeptide having FGF2 activity and improved temperature stability and protease resistance. The polypeptide includes at least one substitution selected from a substitution of aspartic acid (D) with glutamic acid (E) at position 28, a substitution of cysteine (C) with isoleucine (I) or leucine (L) at position 78, or a substitution of cysteine (C) with isoleucine (I) or tryptophan (W) at position 96 in SEQ ID NO: 1.

Abstract: A method for determining heat and reflected heat in a thermal image, according to the present invention, comprises the steps of: a) photographing a subject through a thermal imaging camera so as to collect a thermal image of the subject; b) analyzing features according to the thermal image temperature distribution of the thermal image; c) detecting the heat and the reflected heat in the thermal image according to the analysis in step b); and d) displaying, as heat and reflected heat regions in the thermal image, the heat and the reflected heat in the thermal image detected in step c).

Abstract: A vibration measurement error determination method according to an embodiment of the present invention comprises: a vibration data acquisition step for acquiring vibration data by measuring a vibration generated in a structure; a first determination step for determining, on the basis of a preset error data selection rule, whether the vibration data is data generated by a measurement error; a second determination step for using a machine-learning algorithm to determine whether the vibration data is data generated by a measurement error; and a final determination step for determining, on the basis of the results determined in the first determination step and the second determination step, whether the vibration data is data generated by a measurement error.

Abstract: The present disclosure relates to a cell culture medium composition and a preparation method therefor. By replacing an animal serum with a Spirulina hydrolysate, cell growth can be induced and cell proliferation can be promoted to a level greater than or equal to that of a medium containing an animal serum, while significantly reducing the added amount of animal serum.

Abstract: The present disclosure provides a resource-circulation-type and eco-friendly livestock manure treatment method, and a system for producing algal biomass used therein, the method being capable of: preventing water pollution while allowing livestock liquid fertilizer to be treated on the basis of a biological process; producing algal biomass; and supplying the produced algal biomass to livestock feed and farms.

Abstract: A thermally stable polypeptide having FGF7 activity is provided. The polypeptide is a thermally stable polypeptide having FGF7 activity, wherein, in SEQ ID NO: 1, a 120th alanine (A) is substituted with cysteine (C), one including at least one substitution selected from substitution of a 126th lysine (K) with aspartic acid (D) and a 178th lysine (K) with glutamic acid (E) or aspartic acid (D) forms a salt bridge with a 175th arginine (R), and a 133rd cysteine (C) and a 137th cysteine (C) are disulfide bonded.

Abstract: Disclosed are an array substrate, a display panel and a method for repairing bad spots on the panel. The array substrate includes a substrate and a plurality of data lines and a plurality of scan lines provided on the substrate, the plurality of the data lines and a plurality of the scan lines are insulated and intersected mutually to define a plurality of sub-pixel areas provided in an array, each sub-pixel area is provided with a sub-pixel, the sub-pixel includes a plurality of pixel electrodes provided in a same layer and spaced to form a plurality of light-emitting areas, two adjacent pixel electrodes are electrically connected to each other via a connection electrode, and a pixel driving circuit is electrically connected to a corresponding data line, a corresponding scan line, and a corresponding pixel electrode.

Abstract: Provided is a polypeptide having FGF2 activity and improved temperature stability and protease resistance. The polypeptide includes at least one substitution selected from a substitution of aspartic acid (D) with glutamic acid (E) at position 28, a substitution of cysteine (C) with isoleucine (I) or leucine (L) at position 78, or a substitution of cysteine (C) with isoleucine (I) or tryptophan (VV) at position 96 in SEQ ID NO: 1.

Abstract: Disclosed are an array substrate, a display panel, a display device, and a manufacturing method of the array substrate. The array substrate includes a substrate layer, a passivation layer and a filter layer sequentially stacked. A side of the passivation layer facing the filter layer is provided with a concave-convex structure. By setting the concave-convex structure, when the light rays hit the uneven structure, the passivation layer region of the concave-convex structure can function as a lens. According to the principle of light scattering, light is scattered or diffused in the concave-convex structure to increase the propagation paths of light, more light can pass through the passivation layer and the light transmittance is improved. According to the principle of light diffraction, a new light source is formed at the position of the concave-convex structure to increase the light density and the light transmittance is improved.

Abstract: The present invention relates to an antibody or an antigen-binding fragment thereof that has improved binding affinity for endothelin receptor type A. The present invention also relates to an antibody or an antigen-binding fragment thereof that has improved productivity. The antibody developed in the present invention is suitable for use in the treatment and diagnosis of diseases associated with endothelin receptor type A due to its remarkably improved binding affinity for the antigen and high productivity compared to conventional antibodies.

Abstract: An object of the present invention is to preserve the total content of chlorophyll in an extract while increasing the extraction yield of a Spirulina extract. Another object of the present invention is to provide a pharmaceutical composition and health functional food for prevention or treatment of degenerative cranial nerve diseases containing a Spirulina extract as an active ingredient, and to provide a method for treating degenerative cranial nerve diseases using a Spirulina extract. The present invention provides a method for producing a Spirulina extract including the steps of (a) preparing a Spirulina powder; (b) adding 50% to 80% of ethanol to the Spirulina powder and performing an ultrasonic pretreatment at 15° C. to 35° C.; (c) extracting a Spirulina extract at 50° C. to 80° C.; (d) vacuum-concentrating the Spirulina extract; and (e) freeze-drying the vacuum-concentrated Spirulina extract.

Abstract: The present invention relates to a monoclonal antibody or a fragment thereof that recognizes and binds specifically to the extracellular domain of endothelin receptor type A as an antigen. The monoclonal antibody of the present invention is suitable for use in a therapeutic agent for hypertension or cancer associated with endothelin receptor type A.

Abstract: Provided is a display apparatus including a substrate and a semiconductor layer including first and second semiconductor layers. A first gate insulating layer is formed on the semiconductor layer. A first gate wiring overlapping the first semiconductor layer is formed on the first gate insulating layer. A second gate insulating layer is formed on the first gate wiring. A second gate wiring overlapping the second semiconductor layer is formed on the second gate insulating layer. A third gate insulating layer covers the second gate wiring. A driving voltage line intersecting the first and second gate wirings is formed on the third gate insulating layer. A data line intersecting the first and second gate wirings is formed on the third gate insulating layer. A short circuit protection area is formed between the first gate wiring, the second gate wiring, the driving voltage line and the data line.

Abstract: Provided is a display apparatus including a substrate and a semiconductor layer including first and second semiconductor layers. A first gate insulating layer is formed on the semiconductor layer. A first gate wiring overlapping the first semiconductor layer is formed on the first gate insulating layer. A second gate insulating layer is formed on the first gate wiring. A second gate wiring overlapping the second semiconductor layer is formed on the second gate insulating layer. A third gate insulating layer covers the second gate wiring. A driving voltage line intersecting the first and second gate wirings is formed on the third gate insulating layer. A data line intersecting the first and second gate wirings is formed on the third gate insulating layer. A short circuit protection area is formed between the first gate wiring, the second gate wiring, the driving voltage line and the data line.

Abstract: Provided is a display apparatus including a substrate and a semiconductor layer including first and second semiconductor layers. A first gate insulating layer is formed on the semiconductor layer. A first gate wiring overlapping the first semiconductor layer is formed on the first gate insulating layer. A second gate insulating layer is formed on the first gate wiring. A second gate wiring overlapping the second semiconductor layer is formed on the second gate insulating layer. A third gate insulating layer covers the second gate wiring. A driving voltage line intersecting the first and second gate wirings is formed on the third gate insulating layer. A data line intersecting the first and second gate wirings is formed on the third gate insulating layer. A short circuit protection area is formed between the first gate wiring, the second gate wiring, the driving voltage line and the data line.

Abstract: Provided is a display apparatus including a substrate and a semiconductor layer including first and second semiconductor layers. A first gate insulating layer is formed on the semiconductor layer. A first gate wiring overlapping the first semiconductor layer is formed on the first gate insulating layer. A second gate insulating layer is formed on the first gate wiring. A second gate wiring overlapping the second semiconductor layer is formed on the second gate insulating layer. A third gate insulating layer covers the second gate wiring. A driving voltage line intersecting the first and second gate wirings is formed on the third gate insulating layer. A data line intersecting the first and second gate wirings is formed on the third gate insulating layer. A short circuit protection area is formed between the first gate wiring, the second gate wiring, the driving voltage line and the data line.

Abstract: An organic light emitting diode (OLED) display device and a method of manufacturing the same. The device includes a substrate, a thin film transistor (TFT) on the substrate and including an active layer, a gate electrode, a source electrode, and a drain electrode, a first pixel electrode coupled to one of the source and drain electrodes, a rough portion on the first pixel electrode, a second pixel electrode on the rough portion and having a rough pattern, an intermediate layer on the second pixel electrode including an organic emission layer (EML), and an opposing electrode on the intermediate layer.

Abstract: Provided is a display apparatus including a substrate and a semiconductor layer including first and second semiconductor layers. A first gate insulating layer is formed on the semiconductor layer. A first gate wiring overlapping the first semiconductor layer is formed on the first gate insulating layer. A second gate insulating layer is formed on the first gate wiring. A second gate wiring overlapping the second semiconductor layer is formed on the second gate insulating layer. A third gate insulating layer covers the second gate wiring. A driving voltage line intersecting the first and second gate wirings is formed on the third gate insulating layer. A data line intersecting the first and second gate wirings is formed on the third gate insulating layer. A short circuit protection area is formed between the first gate wiring, the second gate wiring, the driving voltage line and the data line.

Abstract: An organic light emitting diode (OLED) display device and a method of manufacturing the same. The device includes a substrate, a thin film transistor (TFT) on the substrate and including an active layer, a gate electrode, a source electrode, and a drain electrode, a first pixel electrode coupled to one of the source and drain electrodes, a rough portion on the first pixel electrode, a second pixel electrode on the rough portion and having a rough pattern, an intermediate layer on the second pixel electrode including an organic emission layer (EML), and an opposing electrode on the intermediate layer.